[Hub]/) : Traits : Height :

chr3:145,086,742-146,574,438

Best TWAS P=9.69e-18 · Best GWAS P=1.62e-16 conditioned to 0.01

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Colon Transverse RP11-274H2.5 0.20 0.11 lasso 8 0.11 7.1e-06 -6.5 6.6 3.0e-11 0.84 0.05 0.92 FALSE
2 GTEx Esophagus Gastroesophageal Junction PLOD2 0.18 0.07 enet 30 0.10 2.3e-04 -6.6 -6.3 2.8e-10 -0.80 0.03 0.94 FALSE
3 GTEx Esophagus Mucosa RP11-274H2.5 0.16 0.03 lasso 4 0.04 1.1e-03 6.1 7.2 4.2e-13 0.96 0.01 0.99 FALSE
4 GTEx Esophagus Muscularis PLOD2 0.08 0.08 enet 12 0.04 1.1e-03 5.9 -7.1 1.2e-12 -0.94 0.04 0.95 FALSE
5 GTEx Lung RP11-274H2.5 0.07 0.03 enet 9 0.00 3.6e-01 -4.8 6.4 1.3e-10 0.85 0.05 0.90 FALSE
6 GTEx Muscle Skeletal PLOD2 0.13 0.08 lasso 5 0.10 1.7e-10 -5.9 -8.6 9.7e-18 -0.77 0.03 0.97 TRUE
7 GTEx Nerve Tibial RP11-274H2.5 0.09 0.09 enet 11 0.04 5.5e-04 7.6 8.0 1.0e-15 0.98 0.01 0.99 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic PLOD2 0.11 0.02 enet 15 0.04 2.1e-03 -6.5 -5.3 1.5e-07 -0.70 0.08 0.78 FALSE
9 GTEx Skin Sun Exposed Lower leg PLOD2 0.09 0.07 lasso 3 0.04 3.1e-04 -4.8 -5.3 1.2e-07 -0.76 0.65 0.33 FALSE
10 GTEx Testis RP11-274H2.5 0.29 0.34 enet 21 0.27 2.2e-12 -6.5 6.6 4.6e-11 0.92 0.38 0.62 FALSE
11 GTEx Thyroid RP11-274H2.5 0.08 0.08 lasso 4 0.06 2.5e-05 5.9 5.9 3.9e-09 0.90 0.10 0.90 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma PLOD2 0.03 0.01 lasso 5 0.02 2.6e-05 -5.9 -7.2 7.0e-13 -0.72 0.19 0.80 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma PLOD2 0.03 0.02 blup 77 0.02 3.6e-03 -4.8 -7.9 3.9e-15 -0.84 0.03 0.32 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma PLOD2 0.19 0.16 lasso 7 0.20 3.2e-20 -4.8 -6.9 4.6e-12 -0.76 0.90 0.10 FALSE