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Traits
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Neuroticism
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chr3:16,154,636-17,814,553
Best TWAS P=8.15e-10 · Best GWAS P=1.16e-10 conditioned to 1
16.2M
16.4M
16.6M
16.8M
17M
17.2M
17.4M
17.6M
17.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
PLCL2
0.10
0.06
lasso
5
0.09
4.5e-07
6.4
6.1
8.1e-10
0.95
0.00
1.00
TRUE
2
METSIM
Adipose
PLCL2
0.08
0.03
lasso
6
0.04
2.3e-06
5.8
5.9
4.5e-09
0.63
0.13
0.87
FALSE
4
YFS
Blood
PLCL2
0.10
0.10
lasso
7
0.11
3.7e-34
6.4
5.5
4.2e-08
0.93
0.00
1.00
FALSE
3
NTR
Blood
PLCL2
0.05
0.02
lasso
5
0.03
1.1e-09
6.4
5.4
6.3e-08
0.92
0.00
1.00
FALSE