Best TWAS P=8.15e-10 · Best GWAS P=1.16e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PLCL2 | 0.10 | 0.06 | lasso | 5 | 0.09 | 4.5e-07 | 6.4 | 6.1 | 8.1e-10 | 0.95 | 0.00 | 1.00 | TRUE |
| 2 | METSIM | Adipose | PLCL2 | 0.08 | 0.03 | lasso | 6 | 0.04 | 2.3e-06 | 5.8 | 5.9 | 4.5e-09 | 0.63 | 0.13 | 0.87 | FALSE |
| 3 | NTR | Blood | PLCL2 | 0.05 | 0.02 | lasso | 5 | 0.03 | 1.1e-09 | 6.4 | 5.4 | 6.3e-08 | 0.92 | 0.00 | 1.00 | FALSE |
| 4 | YFS | Blood | PLCL2 | 0.10 | 0.10 | lasso | 7 | 0.11 | 3.7e-34 | 6.4 | 5.5 | 4.2e-08 | 0.93 | 0.00 | 1.00 | FALSE |