Best TWAS P=9.31e-08 · Best GWAS P=6.91e-07 conditioned to 0.871
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Colon Sigmoid | C1GALT1 | 0.52 | 0.25 | enet | 38 | 0.31 | 1.0e-11 | 4.2 | 5.1 | 2.9e-07 | 0.81 | 0.01 | 0.98 | FALSE |
2 | GTEx | Esophagus Muscularis | C1GALT1 | 0.36 | 0.16 | lasso | 8 | 0.27 | 1.9e-16 | 4.1 | 5.2 | 1.6e-07 | 0.86 | 0.00 | 0.99 | FALSE |
3 | GTEx | Nerve Tibial | C1GALT1 | 0.44 | 0.28 | lasso | 12 | 0.40 | 2.0e-30 | 3.9 | 5.2 | 1.7e-07 | 0.82 | 0.10 | 0.72 | FALSE |
4 | GTEx | Pancreas | C1GALT1 | 0.44 | 0.11 | enet | 24 | 0.22 | 8.8e-10 | 3.9 | 5.2 | 2.2e-07 | 0.84 | 0.01 | 0.97 | FALSE |
5 | GTEx | Skin Sun Exposed Lower leg | C1GALT1 | 0.22 | 0.04 | lasso | 9 | 0.10 | 4.8e-09 | 3.9 | 5.3 | 1.5e-07 | 0.81 | 0.02 | 0.93 | FALSE |
6 | GTEx | Stomach | C1GALT1 | 0.24 | 0.07 | enet | 17 | 0.12 | 1.9e-06 | 5.0 | 5.3 | 1.4e-07 | 0.88 | 0.00 | 0.99 | FALSE |
7 | GTEx | Uterus | C1GALT1 | 0.38 | 0.28 | enet | 8 | 0.32 | 2.0e-07 | 4.8 | 5.3 | 9.3e-08 | 0.94 | 0.01 | 0.96 | TRUE |
8 | METSIM | Adipose | C1GALT1 | 0.22 | 0.16 | lasso | 9 | 0.23 | 5.1e-34 | 4.2 | 5.2 | 2.3e-07 | 0.82 | 0.01 | 0.97 | FALSE |