[Hub]/) : Traits : Type 2 Diabetes (T2D) (2018) :

chr7:6,502,367-7,988,091

Best TWAS P=9.31e-08 · Best GWAS P=6.91e-07 conditioned to 0.871

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Colon Sigmoid C1GALT1 0.52 0.25 enet 38 0.31 1.0e-11 4.2 5.1 2.9e-07 0.81 0.01 0.98 FALSE
2 GTEx Esophagus Muscularis C1GALT1 0.36 0.16 lasso 8 0.27 1.9e-16 4.1 5.2 1.6e-07 0.86 0.00 0.99 FALSE
3 GTEx Nerve Tibial C1GALT1 0.44 0.28 lasso 12 0.40 2.0e-30 3.9 5.2 1.7e-07 0.82 0.10 0.72 FALSE
4 GTEx Pancreas C1GALT1 0.44 0.11 enet 24 0.22 8.8e-10 3.9 5.2 2.2e-07 0.84 0.01 0.97 FALSE
5 GTEx Skin Sun Exposed Lower leg C1GALT1 0.22 0.04 lasso 9 0.10 4.8e-09 3.9 5.3 1.5e-07 0.81 0.02 0.93 FALSE
6 GTEx Stomach C1GALT1 0.24 0.07 enet 17 0.12 1.9e-06 5.0 5.3 1.4e-07 0.88 0.00 0.99 FALSE
7 GTEx Uterus C1GALT1 0.38 0.28 enet 8 0.32 2.0e-07 4.8 5.3 9.3e-08 0.94 0.01 0.96 TRUE
8 METSIM Adipose C1GALT1 0.22 0.16 lasso 9 0.23 5.1e-34 4.2 5.2 2.3e-07 0.82 0.01 0.97 FALSE