Best TWAS P=4.57e-11 · Best GWAS P=1.04e-31 conditioned to 1.46e-20
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | E2F3 | 0.05 | 0.00 | bslmm | 538 | 0.01 | 3.0e-02 | -5.1 | -6.1 | 1.3e-09 | -0.40 | 0.18 | 0.04 | FALSE |
| 2 | GTEx | Brain Nucleus accumbens basal ganglia | E2F3 | 0.30 | 0.04 | lasso | 12 | 0.06 | 1.2e-02 | 4.5 | -6.6 | 4.6e-11 | -0.43 | 0.14 | 0.22 | TRUE |
| 3 | GTEx | Thyroid | CDKAL1 | 0.10 | 0.07 | lasso | 4 | 0.08 | 1.9e-06 | -6.4 | 6.6 | 4.6e-11 | 0.46 | 0.90 | 0.00 | TRUE |