[Hub]/) : Traits : Type 2 Diabetes (T2D) (2018) :

chr10:101,291,593-102,725,979

Best TWAS P=1.51e-08 · Best GWAS P=5.81e-08 conditioned to 0.724

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CWF19L1 0.28 0.22 enet 24 0.25 3.8e-20 -5.4 -5.5 3.7e-08 0.93 0.00 1.00 FALSE
2 GTEx Adipose Visceral Omentum CWF19L1 0.32 0.31 lasso 2 0.29 1.7e-15 -5.4 -5.5 4.6e-08 1.00 0.00 1.00 FALSE
3 GTEx Adrenal Gland CWF19L1 0.23 0.27 lasso 4 0.25 1.4e-09 -5.4 -5.3 9.8e-08 1.00 0.00 1.00 FALSE
4 GTEx Artery Aorta CWF19L1 0.34 0.34 lasso 9 0.31 1.9e-17 -5.4 -5.4 6.2e-08 1.00 0.00 1.00 FALSE
5 GTEx Artery Coronary CWF19L1 0.36 0.24 lasso 4 0.23 3.3e-08 -5.4 -5.2 2.1e-07 0.96 0.01 0.99 FALSE
6 GTEx Artery Tibial CWF19L1 0.24 0.29 lasso 7 0.29 8.2e-23 -5.4 -5.3 1.2e-07 0.99 0.00 1.00 FALSE
7 GTEx Breast Mammary Tissue CWF19L1 0.36 0.21 lasso 8 0.19 3.7e-10 -5.4 -5.2 1.5e-07 0.98 0.00 1.00 FALSE
8 GTEx Cells Transformed fibroblasts CWF19L1 0.46 0.48 lasso 5 0.49 2.3e-41 -5.4 -5.1 2.7e-07 0.99 0.00 1.00 FALSE
9 GTEx Esophagus Gastroesophageal Junction CWF19L1 0.26 0.25 lasso 6 0.25 1.2e-09 -5.4 -5.4 7.4e-08 0.99 0.00 1.00 FALSE
10 GTEx Esophagus Mucosa CWF19L1 0.49 0.46 lasso 14 0.46 6.7e-34 -5.4 -5.3 1.4e-07 0.99 0.00 1.00 FALSE
11 GTEx Esophagus Muscularis CWF19L1 0.40 0.35 lasso 4 0.34 5.4e-21 -5.4 -5.5 4.2e-08 1.00 0.00 1.00 FALSE
12 GTEx Lung CWF19L1 0.29 0.26 enet 12 0.26 1.3e-19 -5.4 -5.4 7.6e-08 0.98 0.00 1.00 FALSE
13 GTEx Nerve Tibial CWF19L1 0.44 0.35 enet 16 0.38 1.5e-28 -5.4 -5.3 1.1e-07 0.97 0.00 1.00 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic CWF19L1 0.38 0.36 enet 12 0.38 4.4e-22 -5.4 -5.3 1.0e-07 0.98 0.00 1.00 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic RP11-316M21.6 0.30 0.14 lasso 5 0.15 1.6e-08 -5.4 -5.7 1.5e-08 0.94 0.00 1.00 TRUE
16 GTEx Skin Sun Exposed Lower leg CWF19L1 0.32 0.32 lasso 4 0.36 1.6e-31 -5.4 -5.4 5.9e-08 0.98 0.00 1.00 FALSE
17 GTEx Stomach CWF19L1 0.26 0.21 lasso 4 0.19 2.5e-09 -5.4 -5.3 8.6e-08 1.00 0.00 1.00 FALSE
18 GTEx Thyroid CWF19L1 0.24 0.26 lasso 4 0.26 7.9e-20 -5.4 -5.2 2.1e-07 0.99 0.00 1.00 FALSE
19 GTEx Thyroid RP11-316M21.6 0.08 0.06 enet 12 0.07 9.3e-06 -4.7 -5.2 2.3e-07 0.96 0.01 0.99 FALSE
20 METSIM Adipose CWF19L1 0.18 0.18 lasso 2 0.18 1.1e-25 -5.4 -5.4 6.8e-08 1.00 0.00 1.00 FALSE
21 YFS Blood CWF19L1 0.23 0.28 lasso 4 0.28 8.6e-93 -5.4 -5.4 6.6e-08 1.00 0.00 1.00 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CWF19L1 0.23 0.20 lasso 3 0.20 5.3e-22 -5.4 -5.2 1.5e-07 0.98 0.00 1.00 FALSE
23 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CWF19L1 0.27 0.22 lasso 7 0.22 5.8e-13 -5.4 -5.3 1.4e-07 0.99 0.00 1.00 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma CWF19L1 0.32 0.28 lasso 2 0.27 4.6e-31 -5.4 -5.4 5.9e-08 1.00 0.00 1.00 FALSE
25 The Cancer Genome Atlas Liver Hepatocellular Carcinoma CWF19L1 0.19 0.13 lasso 3 0.11 5.4e-06 -5.4 -5.5 4.4e-08 1.00 0.00 1.00 FALSE
26 The Cancer Genome Atlas Lung Adenocarcinoma CWF19L1 0.13 0.12 lasso 3 0.11 5.6e-13 -5.4 -5.3 9.2e-08 1.00 0.00 1.00 FALSE
27 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CWF19L1 0.34 0.29 lasso 7 0.26 6.5e-11 -5.4 -5.3 9.6e-08 0.99 0.00 1.00 FALSE
28 The Cancer Genome Atlas Prostate Adenocarcinoma CWF19L1 0.29 0.32 lasso 2 0.32 1.0e-34 -5.4 -5.4 5.7e-08 1.00 0.00 1.00 FALSE
29 The Cancer Genome Atlas Skin Cutaneous Melanoma CWF19L1 0.20 0.13 enet 9 0.08 4.4e-03 -5.4 -5.2 2.5e-07 0.97 0.00 0.89 FALSE
30 The Cancer Genome Atlas Thyroid Carcinoma CWF19L1 0.34 0.33 lasso 4 0.33 2.6e-33 -5.4 -5.3 9.7e-08 0.99 0.00 1.00 FALSE