[Hub]/) : Traits : Type 2 Diabetes (T2D) (2018) : ← →

chr10:92,860,281-95,151,622

Best TWAS P=4.35e-28 · Best GWAS P=7.96e-27 conditioned to 0.00179

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts BTAF1 0.20 0.09 enet 39 0.18 2.9e-13 -4.2 -5.6 2.2e-08 0.32 1.00 0.00 FALSE
2 GTEx Esophagus Muscularis EIF2S2P3 0.09 0.04 lasso 6 0.04 1.1e-03 -10.5 -11.0 4.4e-28 0.81 0.02 0.92 TRUE
3 GTEx Lung TNKS2 0.12 0.10 lasso 4 0.11 1.8e-08 4.7 5.1 2.8e-07 -0.05 0.64 0.31 FALSE
4 GTEx Prostate EIF2S2P3 0.21 0.05 lasso 4 0.11 1.1e-03 -10.5 -9.2 2.7e-20 0.78 0.03 0.63 FALSE
5 GTEx Spleen EIF2S2P3 0.32 0.04 enet 15 0.11 1.2e-03 -5.7 -8.3 8.8e-17 0.82 0.03 0.70 FALSE
6 GTEx Testis HHEX 0.11 0.02 enet 8 0.00 4.2e-01 -7.8 -7.1 1.6e-12 0.70 0.09 0.24 FALSE
7 GTEx Thyroid EIF2S2P3 0.15 0.14 lasso 2 0.14 6.2e-11 -10.5 -10.5 1.3e-25 0.88 0.02 0.98 FALSE
8 GTEx Whole Blood EIF2S2P3 0.10 0.02 lasso 6 0.05 2.2e-05 -10.7 -8.8 2.0e-18 0.76 0.00 1.00 FALSE
9 NTR Blood KIF11 0.11 0.10 lasso 8 0.10 3.0e-29 7.2 -7.4 1.2e-13 0.68 1.00 0.00 FALSE
10 YFS Blood HHEX 0.09 0.04 lasso 9 0.08 2.3e-25 -7.8 -5.3 9.8e-08 0.50 1.00 0.00 FALSE
11 YFS Blood MARCH5 0.05 0.06 enet 20 0.08 2.0e-25 -5.8 5.2 1.9e-07 -0.13 1.00 0.00 FALSE
12 The Cancer Genome Atlas Lung Squamous Cell Carcinoma HHEX 0.03 0.00 blup 28 0.02 1.4e-03 -3.5 -6.1 9.3e-10 0.66 0.01 0.31 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma MARCH5 0.07 0.08 enet 15 0.09 7.4e-09 5.5 -5.3 8.8e-08 0.17 0.02 0.98 FALSE
14 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma MARCH5 0.31 0.23 lasso 10 0.21 2.0e-06 -5.4 -5.3 1.3e-07 0.14 0.02 0.98 FALSE