Best TWAS P=3.91e-15 · Best GWAS P=1.02e-16 conditioned to 0.00681
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | ZFP36L2 | 0.06 | 0.00 | lasso | 8 | 0.01 | 3.5e-02 | -7.4 | 5.8 | 7.5e-09 | -0.70 | 0.20 | 0.26 | FALSE |
| 2 | GTEx | Thyroid | AC010883.5 | 0.11 | 0.09 | lasso | 2 | 0.08 | 1.5e-06 | -7.8 | -7.9 | 3.9e-15 | 0.93 | 0.08 | 0.92 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZFP36L2 | 0.03 | 0.01 | blup | 38 | 0.01 | 1.1e-02 | -3.1 | 6.1 | 1.3e-09 | -0.74 | 0.02 | 0.48 | FALSE |