[Hub]/) : Traits : Type 2 Diabetes (T2D) (2018) : ← →

chr2:26,655,745-28,607,344

Best TWAS P=4.35e-15 · Best GWAS P=3.4e-15 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	GTF3C2	0.06	0.09	lasso	8	0.08	7.2e-10	4.9	-5.8	7.5e-09	0.72	0.36	0.64	FALSE
2	CommonMind	Brain Pre-frontal Cortex	IFT172	0.06	0.09	enet	16	0.09	3.9e-11	4.8	6.1	1.3e-09	-0.75	0.44	0.56	FALSE
3	GTEx	Adipose Subcutaneous	AC074117.10	0.06	0.04	lasso	5	0.02	4.8e-03	5.6	-5.8	5.3e-09	0.65	0.50	0.20	FALSE
4	GTEx	Adipose Visceral Omentum	PPM1G	0.06	0.01	lasso	5	0.01	1.1e-01	4.9	-5.2	2.0e-07	0.64	0.11	0.28	FALSE
5	GTEx	Adipose Visceral Omentum	AC074117.10	0.14	0.09	lasso	3	0.08	5.0e-05	5.2	-5.2	2.2e-07	0.60	0.86	0.06	FALSE
6	GTEx	Artery Aorta	AC074117.10	0.06	0.04	lasso	3	0.03	6.8e-03	5.2	-5.2	1.6e-07	0.58	0.25	0.10	FALSE
7	GTEx	Artery Tibial	PPM1G	0.06	0.02	lasso	4	0.03	2.3e-03	5.0	-5.2	1.8e-07	0.66	0.28	0.14	FALSE
8	GTEx	Artery Tibial	AC074117.10	0.13	0.14	lasso	5	0.13	1.1e-10	5.2	-5.4	7.2e-08	0.62	1.00	0.00	FALSE
9	GTEx	Cells Transformed fibroblasts	NRBP1	0.09	0.08	lasso	3	0.08	7.8e-07	5.2	-5.5	3.1e-08	0.61	0.96	0.03	FALSE
10	GTEx	Cells Transformed fibroblasts	AC074117.10	0.21	0.19	enet	23	0.18	1.6e-13	5.6	-5.9	4.6e-09	0.66	0.92	0.08	FALSE
11	GTEx	Colon Sigmoid	AC074117.10	0.13	0.18	lasso	3	0.14	1.1e-05	5.2	-5.2	1.8e-07	0.60	0.87	0.06	FALSE
12	GTEx	Esophagus Gastroesophageal Junction	AC074117.10	0.12	0.13	enet	9	0.09	4.9e-04	4.7	-5.7	1.6e-08	0.64	0.46	0.25	FALSE
13	GTEx	Esophagus Mucosa	AC074117.10	0.12	0.14	lasso	8	0.14	2.1e-09	5.6	-6.2	5.8e-10	0.74	0.93	0.07	FALSE
14	GTEx	Esophagus Muscularis	NRBP1	0.07	0.04	lasso	6	0.04	1.3e-03	5.6	-6.0	2.1e-09	0.82	0.02	0.96	FALSE
15	GTEx	Esophagus Muscularis	AC074117.10	0.17	0.14	enet	5	0.09	6.6e-06	5.6	-5.7	1.3e-08	0.65	0.79	0.19	FALSE
16	GTEx	Lung	NRBP1	0.05	0.05	enet	9	0.05	1.7e-04	5.0	-5.2	2.2e-07	0.61	0.75	0.15	FALSE
17	GTEx	Nerve Tibial	NRBP1	0.06	0.00	enet	9	0.02	2.0e-02	5.6	-5.8	7.5e-09	0.61	0.35	0.52	FALSE
18	GTEx	Ovary	AC074117.10	0.16	0.04	enet	9	0.05	2.0e-02	4.9	-5.8	5.9e-09	0.77	0.05	0.76	FALSE
19	GTEx	Skin Sun Exposed Lower leg	SLC4A1AP	0.04	0.01	lasso	3	0.02	1.7e-02	4.8	5.2	1.8e-07	-0.60	0.21	0.11	FALSE
20	GTEx	Testis	NRBP1	0.16	0.09	lasso	3	0.06	1.8e-03	5.6	-6.5	7.1e-11	0.80	0.03	0.96	FALSE
21	GTEx	Testis	AC074117.10	0.14	0.08	lasso	6	0.12	4.5e-06	4.7	-6.8	1.0e-11	0.85	0.04	0.96	FALSE
22	GTEx	Vagina	AC074117.10	0.14	0.04	enet	13	0.06	1.4e-02	4.5	-5.3	1.3e-07	0.72	0.09	0.50	FALSE
23	METSIM	Adipose	NRBP1	0.06	0.09	lasso	3	0.08	1.6e-12	5.6	-5.8	9.0e-09	0.67	1.00	0.00	FALSE
24	METSIM	Adipose	PREB	0.04	0.01	bslmm	302	0.02	5.6e-04	2.2	5.2	2.2e-07	-0.36	0.08	0.28	FALSE
25	ROSMAP	Brain Pre-frontal Cortex	IFT172	0.07	0.02	blup	287	0.03	5.8e-05	5.2	5.5	4.2e-08	-0.63	0.43	0.49	FALSE
26	YFS	Blood	NRBP1	0.01	0.01	lasso	6	0.01	9.1e-06	4.7	-5.2	2.2e-07	0.61	0.99	0.01	FALSE
27	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PPM1G	0.03	0.02	blup	31	0.02	8.8e-03	4.8	-5.3	1.1e-07	0.66	0.02	0.69	FALSE
28	The Cancer Genome Atlas	Glioblastoma Multiforme	NRBP1	0.15	0.10	lasso	2	0.10	5.8e-04	5.6	-5.6	2.1e-08	0.67	0.00	0.72	FALSE
29	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FNDC4	0.13	0.06	lasso	2	0.05	1.1e-03	-7.9	7.8	4.4e-15	-0.99	0.00	0.94	TRUE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	NRBP1	0.03	0.03	blup	30	0.03	2.2e-04	4.5	-5.3	1.3e-07	0.64	0.03	0.95	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	NRBP1	0.03	0.01	blup	30	0.02	5.3e-03	5.6	-5.2	2.2e-07	0.62	0.02	0.95	FALSE