[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr1:85,416,796-86,865,383

Best TWAS P=9.05e-16 · Best GWAS P=2.95e-14 conditioned to 0.466

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ZNHIT6	0.13	0.08	lasso	8	0.09	5.5e-08	6.0	-6.0	1.5e-09	-0.37	0.99	0.01	FALSE
2	GTEx	Artery Aorta	ZNHIT6	0.25	0.24	enet	20	0.28	1.3e-15	6.0	-5.5	3.4e-08	-0.32	0.99	0.01	FALSE
3	GTEx	Artery Coronary	ZNHIT6	0.14	0.06	lasso	5	0.06	4.2e-03	5.5	-5.3	1.3e-07	-0.32	0.19	0.04	FALSE
4	GTEx	Artery Tibial	ZNHIT6	0.20	0.17	lasso	4	0.18	6.6e-14	5.5	-5.5	3.1e-08	-0.33	1.00	0.00	FALSE
5	GTEx	Breast Mammary Tissue (Female)	ZNHIT6	0.09	0.09	lasso	2	0.04	3.3e-02	3.9	-5.2	2.2e-07	-0.41	0.09	0.06	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	ZNHIT6	0.41	0.41	enet	9	0.23	4.3e-08	5.5	-5.6	2.5e-08	-0.34	1.00	0.00	FALSE
7	GTEx	Cells Transformed fibroblasts	ZNHIT6	0.14	0.08	enet	10	0.08	1.7e-06	6.0	-5.6	2.0e-08	-0.28	0.98	0.01	FALSE
8	GTEx	Colon Sigmoid	ZNHIT6	0.19	0.14	enet	16	0.09	3.2e-04	6.0	-5.6	2.1e-08	-0.30	0.70	0.06	FALSE
9	GTEx	Colon Transverse	ZNHIT6	0.33	0.27	lasso	6	0.30	6.3e-15	-5.9	-6.2	6.3e-10	-0.35	0.99	0.01	FALSE
10	GTEx	Esophagus Mucosa	ZNHIT6	0.17	0.13	lasso	4	0.13	5.7e-09	6.0	-6.0	2.1e-09	-0.38	0.99	0.01	FALSE
11	GTEx	Esophagus Muscularis	ZNHIT6	0.31	0.26	lasso	6	0.28	3.3e-17	5.5	-6.1	9.0e-10	-0.36	1.00	0.00	FALSE
12	GTEx	Lung	ZNHIT6	0.22	0.12	lasso	12	0.11	6.3e-09	-5.9	-6.1	1.2e-09	-0.35	1.00	0.00	FALSE
13	GTEx	Nerve Tibial	ZNHIT6	0.17	0.08	lasso	6	0.09	7.1e-07	5.8	-6.2	4.5e-10	-0.34	0.95	0.04	FALSE
14	GTEx	Prostate	ZNHIT6	0.26	0.25	enet	13	0.18	2.1e-05	6.0	-6.1	8.0e-10	-0.37	0.77	0.06	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	ZNHIT6	0.20	0.18	enet	15	0.19	1.6e-10	6.0	-6.0	2.0e-09	-0.38	0.99	0.01	FALSE
16	GTEx	Skin Sun Exposed Lower leg	ZNHIT6	0.11	0.16	enet	12	0.13	5.7e-11	5.5	-5.9	3.3e-09	-0.35	0.99	0.01	FALSE
17	GTEx	Spleen	ZNHIT6	0.40	0.25	lasso	6	0.30	2.7e-08	-5.9	-5.2	1.7e-07	-0.32	0.72	0.04	FALSE
18	GTEx	Stomach	ZNHIT6	0.22	0.17	enet	28	0.15	9.6e-08	-5.9	-6.7	1.7e-11	-0.44	0.95	0.03	FALSE
19	GTEx	Testis	ZNHIT6	0.22	0.23	lasso	4	0.22	6.4e-10	5.5	-5.5	3.9e-08	-0.34	1.00	0.00	FALSE
20	GTEx	Thyroid	ZNHIT6	0.18	0.12	enet	31	0.16	2.8e-12	5.5	-7.2	8.6e-13	-0.54	0.97	0.03	FALSE
21	GTEx	Uterus	ZNHIT6	0.27	0.20	lasso	4	0.16	3.2e-04	5.5	-5.3	1.4e-07	-0.33	0.18	0.05	FALSE
22	ROSMAP	Brain Pre-frontal Cortex	ZNHIT6	0.11	0.12	enet	15	0.14	1.5e-17	7.5	-8.0	9.0e-16	-0.91	0.00	1.00	TRUE
23	YFS	Blood	ZNHIT6	0.10	0.07	lasso	10	0.12	9.1e-38	-5.9	-5.5	3.2e-08	-0.32	1.00	0.00	FALSE
24	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	ZNHIT6	0.07	0.08	lasso	3	0.05	2.4e-03	6.1	-6.1	9.9e-10	-0.37	0.03	0.92	FALSE
25	The Cancer Genome Atlas	Colon Adenocarcinoma	ZNHIT6	0.07	0.04	blup	70	0.05	1.3e-03	6.0	-5.7	1.2e-08	-0.32	0.03	0.86	FALSE
26	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZNHIT6	0.05	0.05	lasso	5	0.05	2.0e-06	6.3	-6.6	4.3e-11	-0.34	0.02	0.98	FALSE
27	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ZNHIT6	0.05	0.03	blup	70	0.03	9.5e-03	6.0	-5.8	6.5e-09	-0.33	0.04	0.71	FALSE
28	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNHIT6	0.04	0.02	blup	70	0.02	1.0e-03	6.1	-5.3	9.7e-08	-0.27	0.06	0.90	FALSE
29	The Cancer Genome Atlas	Lung Adenocarcinoma	ZNHIT6	0.02	0.03	lasso	4	0.02	9.5e-04	5.5	-5.5	3.2e-08	-0.33	0.08	0.65	FALSE
30	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ZNHIT6	0.03	0.01	enet	8	0.02	1.3e-03	-5.2	-5.2	2.0e-07	-0.30	0.01	0.83	FALSE
31	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ZNHIT6	0.15	0.12	enet	9	0.10	7.7e-05	-5.9	-5.2	1.5e-07	-0.26	0.05	0.84	FALSE
32	The Cancer Genome Atlas	Rectum Adenocarcinoma	ZNHIT6	0.29	0.18	lasso	4	0.11	1.8e-03	-5.9	-5.9	2.9e-09	-0.32	0.07	0.66	FALSE