[Hub]/) : Traits : Waist Hip Ratio (WHR) :

chr1:85,416,796-86,865,383

Best TWAS P=9.05e-16 · Best GWAS P=2.95e-14 conditioned to 0.466

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous ZNHIT6 0.13 0.08 lasso 8 0.09 5.5e-08 6.0 -6.0 1.5e-09 -0.37 0.99 0.01 FALSE
2 GTEx Artery Aorta ZNHIT6 0.25 0.24 enet 20 0.28 1.3e-15 6.0 -5.5 3.4e-08 -0.32 0.99 0.01 FALSE
3 GTEx Artery Coronary ZNHIT6 0.14 0.06 lasso 5 0.06 4.2e-03 5.5 -5.3 1.3e-07 -0.32 0.19 0.04 FALSE
4 GTEx Artery Tibial ZNHIT6 0.20 0.17 lasso 4 0.18 6.6e-14 5.5 -5.5 3.1e-08 -0.33 1.00 0.00 FALSE
5 GTEx Breast Mammary Tissue (Female) ZNHIT6 0.09 0.09 lasso 2 0.04 3.3e-02 3.9 -5.2 2.2e-07 -0.41 0.09 0.06 FALSE
6 GTEx Cells EBV-transformed lymphocytes ZNHIT6 0.41 0.41 enet 9 0.23 4.3e-08 5.5 -5.6 2.5e-08 -0.34 1.00 0.00 FALSE
7 GTEx Cells Transformed fibroblasts ZNHIT6 0.14 0.08 enet 10 0.08 1.7e-06 6.0 -5.6 2.0e-08 -0.28 0.98 0.01 FALSE
8 GTEx Colon Sigmoid ZNHIT6 0.19 0.14 enet 16 0.09 3.2e-04 6.0 -5.6 2.1e-08 -0.30 0.70 0.06 FALSE
9 GTEx Colon Transverse ZNHIT6 0.33 0.27 lasso 6 0.30 6.3e-15 -5.9 -6.2 6.3e-10 -0.35 0.99 0.01 FALSE
10 GTEx Esophagus Mucosa ZNHIT6 0.17 0.13 lasso 4 0.13 5.7e-09 6.0 -6.0 2.1e-09 -0.38 0.99 0.01 FALSE
11 GTEx Esophagus Muscularis ZNHIT6 0.31 0.26 lasso 6 0.28 3.3e-17 5.5 -6.1 9.0e-10 -0.36 1.00 0.00 FALSE
12 GTEx Lung ZNHIT6 0.22 0.12 lasso 12 0.11 6.3e-09 -5.9 -6.1 1.2e-09 -0.35 1.00 0.00 FALSE
13 GTEx Nerve Tibial ZNHIT6 0.17 0.08 lasso 6 0.09 7.1e-07 5.8 -6.2 4.5e-10 -0.34 0.95 0.04 FALSE
14 GTEx Prostate ZNHIT6 0.26 0.25 enet 13 0.18 2.1e-05 6.0 -6.1 8.0e-10 -0.37 0.77 0.06 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic ZNHIT6 0.20 0.18 enet 15 0.19 1.6e-10 6.0 -6.0 2.0e-09 -0.38 0.99 0.01 FALSE
16 GTEx Skin Sun Exposed Lower leg ZNHIT6 0.11 0.16 enet 12 0.13 5.7e-11 5.5 -5.9 3.3e-09 -0.35 0.99 0.01 FALSE
17 GTEx Spleen ZNHIT6 0.40 0.25 lasso 6 0.30 2.7e-08 -5.9 -5.2 1.7e-07 -0.32 0.72 0.04 FALSE
18 GTEx Stomach ZNHIT6 0.22 0.17 enet 28 0.15 9.6e-08 -5.9 -6.7 1.7e-11 -0.44 0.95 0.03 FALSE
19 GTEx Testis ZNHIT6 0.22 0.23 lasso 4 0.22 6.4e-10 5.5 -5.5 3.9e-08 -0.34 1.00 0.00 FALSE
20 GTEx Thyroid ZNHIT6 0.18 0.12 enet 31 0.16 2.8e-12 5.5 -7.2 8.6e-13 -0.54 0.97 0.03 FALSE
21 GTEx Uterus ZNHIT6 0.27 0.20 lasso 4 0.16 3.2e-04 5.5 -5.3 1.4e-07 -0.33 0.18 0.05 FALSE
22 ROSMAP Brain Pre-frontal Cortex ZNHIT6 0.11 0.12 enet 15 0.14 1.5e-17 7.5 -8.0 9.0e-16 -0.91 0.00 1.00 TRUE
23 YFS Blood ZNHIT6 0.10 0.07 lasso 10 0.12 9.1e-38 -5.9 -5.5 3.2e-08 -0.32 1.00 0.00 FALSE
24 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma ZNHIT6 0.07 0.08 lasso 3 0.05 2.4e-03 6.1 -6.1 9.9e-10 -0.37 0.03 0.92 FALSE
25 The Cancer Genome Atlas Colon Adenocarcinoma ZNHIT6 0.07 0.04 blup 70 0.05 1.3e-03 6.0 -5.7 1.2e-08 -0.32 0.03 0.86 FALSE
26 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ZNHIT6 0.05 0.05 lasso 5 0.05 2.0e-06 6.3 -6.6 4.3e-11 -0.34 0.02 0.98 FALSE
27 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ZNHIT6 0.05 0.03 blup 70 0.03 9.5e-03 6.0 -5.8 6.5e-09 -0.33 0.04 0.71 FALSE
28 The Cancer Genome Atlas Brain Lower Grade Glioma ZNHIT6 0.04 0.02 blup 70 0.02 1.0e-03 6.1 -5.3 9.7e-08 -0.27 0.06 0.90 FALSE
29 The Cancer Genome Atlas Lung Adenocarcinoma ZNHIT6 0.02 0.03 lasso 4 0.02 9.5e-04 5.5 -5.5 3.2e-08 -0.33 0.08 0.65 FALSE
30 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ZNHIT6 0.03 0.01 enet 8 0.02 1.3e-03 -5.2 -5.2 2.0e-07 -0.30 0.01 0.83 FALSE
31 The Cancer Genome Atlas Pancreatic Adenocarcinoma ZNHIT6 0.15 0.12 enet 9 0.10 7.7e-05 -5.9 -5.2 1.5e-07 -0.26 0.05 0.84 FALSE
32 The Cancer Genome Atlas Rectum Adenocarcinoma ZNHIT6 0.29 0.18 lasso 4 0.11 1.8e-03 -5.9 -5.9 2.9e-09 -0.32 0.07 0.66 FALSE