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Traits
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Traits
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Verbal and Numeric Reasoning (VNR)
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chr6:24,382,897-26,689,223
Best TWAS P=4.38e-08 · Best GWAS P=6.39e-15 conditioned to 8.38e-06
24.5M
25M
25.5M
26M
26.5M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
NTR
Blood
CMAH
0.08
0.04
enet
20
0.07
2.4e-20
3.56
5.5
4.4e-08
0.30
0.88
0.08
TRUE
2
GTEx
Brain Cortex
CMAHP
0.30
0.05
lasso
5
0.10
1.2e-03
2.26
5.4
7.8e-08
0.24
0.09
0.20
TRUE
1
GTEx
Artery Tibial
U91328.21
0.09
0.01
lasso
8
0.01
3.0e-02
-0.06
-5.4
8.4e-08
-0.53
0.04
0.87
TRUE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
CMAH
0.13
0.12
blup
112
0.11
1.1e-12
3.31
5.2
1.7e-07
0.28
0.70
0.10
FALSE