Best TWAS P=4.38e-08 · Best GWAS P=6.39e-15 conditioned to 8.38e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | U91328.21 | 0.09 | 0.01 | lasso | 8 | 0.01 | 3.0e-02 | -0.06 | -5.4 | 8.4e-08 | -0.53 | 0.04 | 0.87 | TRUE |
| 2 | GTEx | Brain Cortex | CMAHP | 0.30 | 0.05 | lasso | 5 | 0.10 | 1.2e-03 | 2.26 | 5.4 | 7.8e-08 | 0.24 | 0.09 | 0.20 | TRUE |
| 3 | NTR | Blood | CMAH | 0.08 | 0.04 | enet | 20 | 0.07 | 2.4e-20 | 3.56 | 5.5 | 4.4e-08 | 0.30 | 0.88 | 0.08 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CMAH | 0.13 | 0.12 | blup | 112 | 0.11 | 1.1e-12 | 3.31 | 5.2 | 1.7e-07 | 0.28 | 0.70 | 0.10 | FALSE |