Best TWAS P=2.58e-09 · Best GWAS P=3.4e-11 conditioned to 0.00346
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | LMBR1L | 0.07 | 0.03 | lasso | 5 | 0.04 | 1.8e-03 | 5.1 | -5.2 | 1.8e-07 | -0.84 | 0.02 | 0.96 | FALSE |
| 2 | GTEx | Muscle Skeletal | RP11-386G11.5 | 0.09 | 0.07 | enet | 17 | 0.08 | 7.4e-08 | 6.3 | -5.8 | 7.7e-09 | -0.93 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Nerve Tibial | LMBR1L | 0.08 | 0.04 | lasso | 4 | 0.06 | 3.1e-05 | 6.1 | -5.1 | 2.7e-07 | -0.84 | 0.03 | 0.96 | FALSE |
| 4 | GTEx | Testis | PRKAG1 | 0.17 | 0.11 | lasso | 5 | 0.09 | 1.2e-04 | 5.1 | -6.0 | 2.6e-09 | -0.92 | 0.01 | 0.99 | TRUE |