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Verbal and Numeric Reasoning (VNR)
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chr12:48,698,518-50,199,949
Best TWAS P=2.58e-09 · Best GWAS P=3.4e-11 conditioned to 0.00346
48.8M
49M
49.2M
49.4M
49.6M
49.8M
50M
50.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
GTEx
Testis
PRKAG1
0.17
0.11
lasso
5
0.09
1.2e-04
5.1
-6.0
2.6e-09
-0.92
0.01
0.99
TRUE
2
GTEx
Muscle Skeletal
RP11-386G11.5
0.09
0.07
enet
17
0.08
7.4e-08
6.3
-5.8
7.7e-09
-0.93
0.00
1.00
FALSE
1
GTEx
Esophagus Mucosa
LMBR1L
0.07
0.03
lasso
5
0.04
1.8e-03
5.1
-5.2
1.8e-07
-0.84
0.02
0.96
FALSE
3
GTEx
Nerve Tibial
LMBR1L
0.08
0.04
lasso
4
0.06
3.1e-05
6.1
-5.1
2.7e-07
-0.84
0.03
0.96
FALSE