Best TWAS P=1.2e-08 · Best GWAS P=7.61e-07 conditioned to 0.605
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | ARL6IP4 | 0.08 | 0.02 | lasso | 5 | 0.06 | 3.7e-04 | -4.7 | -5.3 | 1.4e-07 | 0.87 | 0.04 | 0.78 | FALSE |
2 | GTEx | Cells Transformed fibroblasts | ARL6IP4 | 0.12 | 0.13 | lasso | 2 | 0.12 | 4.0e-09 | 4.6 | -5.1 | 2.8e-07 | 0.76 | 0.04 | 0.94 | FALSE |
3 | GTEx | Pancreas | ABCB9 | 0.12 | 0.00 | lasso | 12 | -0.01 | 6.3e-01 | -4.7 | 5.2 | 1.6e-07 | -0.87 | 0.03 | 0.51 | FALSE |
4 | NTR | Blood | ARL6IP4 | 0.01 | 0.02 | enet | 9 | 0.01 | 9.8e-06 | -4.7 | -5.7 | 1.2e-08 | 0.91 | 0.02 | 0.96 | TRUE |