[Hub]/) : Traits : Blood White Count : ← →

chr6:108,994,161-110,710,018

Best TWAS P=2.38e-16 · Best GWAS P=1.31e-22 conditioned to 0.000134

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SMPD2 0.14 0.10 lasso 10 0.12 2.3e-10 4.6 7.0 3.0e-12 0.46 0.97 0.03 FALSE
2 GTEx Artery Coronary SMPD2 0.11 0.09 lasso 4 0.07 1.9e-03 5.3 5.3 1.1e-07 0.24 0.36 0.04 FALSE
3 GTEx Brain Cortex AK9 0.21 0.03 enet 29 0.16 3.2e-05 3.8 -5.2 1.8e-07 -0.32 0.56 0.10 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia AK9 0.28 0.02 enet 22 0.09 1.8e-03 3.8 -5.4 7.2e-08 -0.18 0.23 0.09 TRUE
5 GTEx Cells Transformed fibroblasts CD164 0.14 0.07 lasso 6 0.05 1.9e-04 8.2 8.2 2.4e-16 0.83 0.90 0.03 TRUE
6 GTEx Esophagus Gastroesophageal Junction SMPD2 0.11 0.06 lasso 6 0.06 4.1e-03 5.3 5.2 2.0e-07 0.25 0.36 0.04 FALSE
7 GTEx Muscle Skeletal CD164 0.07 0.07 enet 15 0.06 3.7e-06 -5.5 -6.5 9.8e-11 -0.67 0.98 0.02 FALSE
8 GTEx Stomach SMPD2 0.14 -0.01 lasso 5 -0.01 8.6e-01 4.1 6.0 1.7e-09 0.46 0.06 0.21 FALSE
9 ROSMAP Brain Pre-frontal Cortex CD164 0.07 0.01 enet 16 0.05 1.6e-07 4.4 -6.4 1.6e-10 -0.45 0.59 0.30 FALSE
10 YFS Blood CD164 0.03 0.01 blup 382 0.02 1.9e-07 -5.5 5.3 9.0e-08 0.57 0.80 0.20 FALSE
11 The Cancer Genome Atlas Esophageal Carcinoma C6orf182 0.10 -0.01 blup 40 0.03 4.2e-02 7.6 5.9 3.7e-09 0.58 0.02 0.45 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma CD164 0.03 0.01 blup 49 0.01 2.1e-02 4.6 7.1 1.3e-12 0.44 0.08 0.15 FALSE