Hub : Genes

CD164

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1130	0.0320	1.4e-10	0.072	0.103	0.095	0.102	0.098	4.0e-09	1.5e-12	1.2e-11	2.0e-12	6.5e-12
2	GTEx	Cells Transformed fibroblasts	0.1450	0.0510	3.0e-05	0.067	NA	0.014	NA	0.047	9.3e-06	NA	3.0e-02	NA	1.9e-04
3	GTEx	Esophagus Muscularis	0.0420	0.0210	9.3e-03	0.016	NA	0.008	NA	0.007	3.3e-02	NA	1.0e-01	NA	1.2e-01
4	GTEx	Muscle Skeletal	0.0747	0.0279	9.1e-05	0.068	NA	0.055	NA	0.054	3.0e-07	NA	3.7e-06	NA	5.4e-06
5	NTR	Blood	0.0130	0.0072	2.0e-03	0.000	0.003	0.003	0.004	0.002	3.4e-01	2.2e-02	4.0e-02	2.0e-02	5.5e-02
6	ROSMAP	Brain Pre-frontal Cortex	0.0700	0.0279	5.2e-06	0.006	0.039	0.054	0.041	0.038	5.0e-02	8.7e-06	1.6e-07	4.2e-06	1.0e-05
7	YFS	Blood	0.0259	0.0097	7.8e-07	0.011	0.021	0.018	0.020	0.018	1.3e-04	1.9e-07	9.0e-07	2.7e-07	1.2e-06
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0631	0.0328	9.2e-04	0.001	0.018	0.021	NA	0.012	2.3e-01	3.5e-03	2.0e-03	NA	1.4e-02
9	TCGA	Thyroid Carcinoma	0.0350	0.0210	2.5e-03	0.011	0.012	-0.003	NA	0.002	2.5e-02	2.1e-02	8.2e-01	NA	2.1e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.4	0.6	1.7	-1.3	-0.3	0.9	0.1	0.7	-0.4	1.0	0.9	0.2
Bipolar Disorder or Schizophrenia	0.4	1.0	3.4	-1.8	0.1	1.2	-0.3	0.5	-1.3	1.0	0.2	1.0
Depressed Affect (Nagel 2018)	0.4	0.7	2.1	-0.4	-0.6	1.4	0.0	-1.4	-0.1	-0.3	1.3	0.6
Depression (Nagel 2018)	0.4	0.6	1.4	-1.0	-0.5	1.2	0.7	-0.9	-0.1	-0.4	0.9	0.6
Intelligence (Savage-Jansen 2018)	0.3	0.8	2.7	-0.5	0.8	0.7	0.3	-0.2	-0.6	-0.0	1.6	1.7
Neuroticism (Nagel 2018)	0.6	1.4	4.2	-1.2	-0.0	2.0	-0.4	-1.1	-1.1	0.2	1.5	1.5
Schizophrenia (2018)	0.3	0.7	1.9	-1.3	0.4	0.8	-0.5	0.1	-1.4	0.4	-0.3	1.2
Schizophrenia vs Biploar Disorder	0.7	0.9	1.6	1.3	0.6	-1.3	-0.1	1.0	0.9	0.3	-1.2	-1.1
Worry (Nagel 2018)	0.2	0.3	1.4	0.0	-0.3	0.6	0.1	-1.1	0.4	-0.1	1.2	0.0
Alzheimer’s Disease (in mother)	0.9	1.0	5.2	-1.0	-2.3	0.9	0.7	-0.8	-0.7	-0.3	-0.3	0.1
Alzheimer’s Disease (in father)	1.1	1.2	2.6	-1.6	1.0	-0.2	-1.4	0.5	-1.1	0.8	-1.6	0.6
Alzheimer’s Disease (including proxy)	1.9	2.8	8.1	-2.9	-0.4	1.5	-1.1	-0.3	-2.7	0.6	-1.8	1.5
Crohns Disease (2017)	0.6	1.4	3.7	1.7	0.2	-1.0	0.7	1.0	1.7	0.6	-0.2	-1.9
Irritable Bowel Disease (IBD)	0.7	1.7	4.2	0.3	0.5	-1.3	-0.5	1.9	1.2	1.4	-1.2	-2.1
Ulcerative Colitis (UC)	0.7	1.3	3.2	-0.9	0.4	-0.9	-1.1	1.8	0.3	1.3	-1.4	-1.4
Major Depression (MDD)	2.1	2.5	10.6	-0.7	-0.8	2.1	1.6	-1.2	-0.7	-0.3	3.3	1.4
Reaction Time	0.7	1.4	3.0	-1.6	-0.8	1.6	0.6	-0.0	-1.7	0.7	1.4	0.7
Verbal and Numeric Reasoning (VNR)	0.4	0.9	3.7	-0.7	0.7	0.9	0.4	0.4	-1.2	0.3	1.9	1.1
Breast Cancer	0.5	1.1	4.9	0.1	1.2	1.5	-0.5	-0.1	-0.9	0.7	0.1	2.2
Ovarian Cancer	0.3	0.4	1.0	-0.1	0.7	-0.9	0.5	-1.0	-0.6	-0.9	0.0	0.6
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	1.1	1.7	5.5	-1.3	-1.1	2.3	0.2	-0.9	-1.4	-0.0	1.0	1.7
Bipolar Disorder (2011)	4.6	4.4	12.7	-3.6	-0.1	2.5	-0.6	0.4	-3.0	1.8	1.6	2.4
Body Mass Index (BMI) (2010)	3.8	5.2	14.3	3.0	-1.5	-2.3	1.7	-0.1	2.8	-1.5	-1.8	-3.8
Coronary Artery Disease (CAD)	0.2	0.2	0.9	-0.0	1.0	-0.3	-0.0	-0.1	-0.5	-0.6	0.4	0.0
Crohns Disease (2012)	0.6	1.0	3.6	1.5	-0.7	-0.3	1.9	0.1	1.2	-0.0	0.4	-1.1
Mean Putamen Volume	1.4	1.6	4.9	-0.5	-1.3	1.0	1.9	-2.2	0.0	-1.2	1.2	0.4
Fasting Glucose	0.9	1.1	5.2	2.3	-0.1	-0.5	0.5	-0.3	1.1	-1.1	-0.9	-0.9
HbA1C	6.5	7.2	14.9	3.6	-3.9	-0.5	3.5	-1.9	3.4	-1.9	0.1	-2.4
HDL Cholesterol	3.1	5.1	15.3	-1.8	3.2	-0.3	-3.9	2.6	-1.7	2.5	-1.1	0.7
LDL Cholesterol	2.1	3.4	9.6	-2.5	-0.9	3.1	-0.9	-0.8	-1.8	1.2	1.3	2.5
Lupus	0.1	0.1	0.6	-0.0	-0.2	0.4	-0.1	0.7	-0.2	0.7	-0.2	0.3
Neuroticism (2016)	0.8	1.2	2.8	0.3	0.4	1.7	1.2	-0.4	-0.9	-0.7	1.7	1.4
Primary Biliary Cirrhosis	1.6	2.3	5.5	-1.5	1.0	1.6	-2.0	-0.3	-1.7	1.5	-0.2	2.3
Rheumatoid Arthritis	1.5	2.0	5.6	0.4	-1.3	-2.2	-0.3	0.3	1.3	-0.0	-2.0	-2.4
Schizophrenia (2014)	1.0	2.1	5.2	-1.9	1.0	1.4	-1.1	0.9	-2.3	1.6	-0.4	1.7
Triglycerides	1.1	1.8	5.5	-0.6	0.9	1.5	-1.7	-0.1	-1.7	1.1	0.0	2.3
Type 2 Diabetes (T2D) (2012)	1.0	1.2	3.6	1.9	0.5	0.3	1.9	-0.5	0.9	-0.8	0.8	-0.8
Ulcerative Colitis	0.3	0.4	0.9	-0.8	-0.5	-0.3	0.5	0.9	0.1	0.7	-0.5	-0.9
Blood Eosinophil Count	4.3	32.9	59.1	-7.4	3.3	6.3	-6.1	3.3	-7.0	5.7	1.7	7.7
Blood Platelet Count	5.5	63.4	85.7	-7.6	9.3	6.9	-8.0	8.1	-9.2	9.0	2.0	9.0
Blood Red Count	29.4	283.5	615.0	16.8	-24.8	-2.2	20.9	-20.1	17.7	-17.6	1.9	-13.5
Blood White Count	4.4	32.8	67.3	-5.0	8.2	3.5	-6.5	5.1	-6.4	5.3	1.6	7.1
Heel T-Score	2.8	22.0	43.4	4.5	-5.6	-1.0	5.8	-5.7	4.5	-6.6	2.8	-3.0
BMI	1.4	8.3	16.8	2.4	-2.4	-1.2	4.1	-2.0	3.6	-3.2	2.5	-3.3
Height	4.3	83.2	204.5	11.7	1.6	-14.3	5.0	-3.4	10.4	-8.5	-6.2	-12.2
Waist Hip Ratio (WHR)	1.1	4.9	15.7	0.4	-3.5	1.5	2.0	-4.0	0.5	-2.9	0.9	0.5
Systolic Blood Pressure	1.0	5.2	12.7	3.6	-1.7	-2.1	1.6	-2.3	2.9	-1.6	-0.4	-2.9
Smoking Status	1.1	2.6	5.1	-2.3	0.9	1.5	-1.2	1.1	-2.1	1.9	0.3	2.0
Allergy or Eczema	0.4	1.2	7.3	-0.2	-2.7	0.2	1.1	-0.1	0.7	-0.1	-0.5	-1.1
Cardiovascular Disease	2.3	7.5	14.2	3.1	-1.6	-2.3	2.5	-3.5	3.8	-3.4	-0.2	-2.4
Hypothyroidism (self reported)	1.3	3.0	8.3	1.1	-0.4	2.9	2.4	-2.0	0.0	-0.7	2.2	1.6
Respiratory disease	2.4	5.3	12.7	-3.6	-0.9	3.5	-1.3	0.7	-2.1	2.9	1.2	2.2
Type 2 Diabetes (T2D) (2018)	0.0	0.1	0.2	0.3	0.0	-0.3	0.1	-0.4	-0.2	-0.0	0.3	-0.2
Lung FEV1/FVC ratio	2.4	12.1	28.9	4.5	-1.6	-3.4	3.1	-4.1	3.2	-5.4	-0.9	-2.9
Lung FVC	1.7	8.8	19.7	0.5	2.2	-4.4	-3.1	3.1	2.1	1.6	-3.7	-3.9
Neuroticism	0.6	1.5	4.3	-1.3	0.5	1.5	-0.8	-0.8	-2.1	0.4	0.6	1.8
Chronotype (morning person)	4.2	9.7	16.6	3.9	-3.3	-2.2	3.5	-2.0	4.1	-2.9	-0.3	-3.9
Hair Pigment	0.1	1.9	6.6	0.4	-1.7	-0.8	1.2	-2.6	0.2	-2.2	0.2	0.5
Tanning	0.0	0.4	1.0	0.6	0.4	-0.8	-0.3	1.0	0.8	0.4	-0.2	-0.7
Hand grip strength (left)	1.5	4.0	10.7	1.4	-1.3	-2.2	2.1	-2.1	2.0	-3.3	-0.4	-2.0
Number of treatments/medications taken	0.7	1.2	3.1	-0.1	-0.8	-0.5	1.8	-1.5	0.8	-1.4	1.4	-0.1
Average weekly spirits intake	0.8	1.0	3.3	0.6	-1.0	0.3	1.1	-1.8	0.2	-1.6	-0.1	0.0
Sensitivity / hurt feelings	1.4	2.4	7.1	-1.5	-0.9	2.7	0.5	-0.5	-1.9	-0.0	1.5	2.2
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.8	-0.7	-0.9	1.3	-0.3	-1.2	-0.1	-0.2	-0.4	0.8
Hearing difficulty/problems: Yes	1.0	1.6	5.4	-0.1	0.8	2.3	0.8	-1.3	-0.5	-0.2	1.1	2.0
Relative age of first facial hair	0.4	0.9	2.0	-1.4	-0.5	0.3	0.2	-1.4	-0.7	-1.1	0.4	1.3
Other serious medical condition/disability diagnosed by doctor	1.9	2.5	7.5	-1.6	0.8	2.4	0.1	-0.2	-1.2	0.3	2.0	2.7
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.4	0.2	0.6	0.1	-0.2	-0.4	-0.0	-0.4	-0.5	0.5
Ever had hysterectomy (womb removed)	0.6	0.6	2.9	-0.3	-0.3	-0.4	-0.9	1.7	-0.3	1.2	-0.2	-0.0
Systolic blood pressure, automated reading	2.4	6.9	19.4	4.4	-1.3	-1.9	2.0	-2.7	3.5	-2.3	0.6	-2.8
Eye problems/disorders: Diabetes related eye disease	0.8	0.8	1.7	-0.5	1.1	-1.1	-0.7	1.2	0.1	1.3	-0.7	-1.0
Angina	0.6	0.8	1.6	-0.4	1.3	0.8	-0.9	1.3	-0.2	0.6	1.2	0.8
Medication for hormone replacement therapy	4.0	4.5	8.7	-2.7	1.3	1.9	-2.2	1.3	-3.0	2.3	-0.1	2.7
Vitamin and mineral supplements	0.6	0.8	2.1	0.4	1.0	-1.4	-1.0	1.4	0.0	-0.3	-1.0	-0.8
Supplements: Zinc	0.7	0.8	2.9	-1.1	-0.1	1.1	-0.5	-0.7	-0.8	0.4	0.6	1.7
Medication: Co-codamol	0.4	0.4	1.3	1.1	0.6	-0.1	0.4	-0.1	0.3	-1.0	1.0	-0.1
Medication: Metformin	0.5	0.7	2.2	-1.0	0.5	0.2	-1.1	0.4	-1.5	1.2	0.3	0.4
Diabetes (father)	0.1	0.2	0.5	0.3	-0.2	-0.6	-0.3	-0.3	0.6	-0.7	0.2	-0.1
Diabetes (mother)	2.2	2.9	8.8	3.0	1.0	-2.2	0.5	0.7	2.1	-0.5	-1.0	-2.2
Severe depression (siblings)	1.2	1.4	3.1	-1.7	0.2	1.1	-1.0	-0.9	-1.7	-0.4	-0.4	1.7
Pack years adult smoking proportion	1.9	2.9	6.3	2.5	-0.9	-0.5	2.4	-0.8	2.5	-1.0	-0.1	-2.2
Impedance of leg (right)	1.5	7.1	19.9	-2.1	0.3	4.5	-0.0	-0.5	-3.7	1.7	2.8	3.9
Leg fat-free mass (left)	5.8	30.6	63.0	6.2	-1.6	-7.9	3.1	-2.3	7.3	-5.5	-3.3	-7.9
Trunk fat percentage	1.7	6.9	14.1	1.9	-2.6	-1.2	3.8	-2.0	2.9	-2.9	2.0	-3.4
Hand grip strength (right)	2.1	5.6	14.3	1.8	-1.0	-3.8	1.5	-1.5	2.6	-3.0	-1.7	-3.0
Townsend deprivation index at recruitment	1.9	2.7	5.6	2.2	-1.6	-1.2	0.7	-0.7	2.3	-0.6	-1.8	-2.4
Current tobacco smoking	0.3	0.5	1.6	-0.9	-0.8	0.7	0.1	0.3	-0.3	1.3	-0.7	-0.2
Average weekly fortified wine intake	2.5	3.0	6.6	-1.0	-0.5	2.6	0.8	-2.2	-1.8	-1.2	2.2	1.9
Maternal smoking around birth	0.8	1.2	4.3	-0.1	-1.6	0.2	0.6	-2.1	0.2	-1.6	-0.9	-0.1
Fed-up feelings	0.1	0.3	1.3	-0.2	-0.6	0.7	0.0	-1.1	0.4	-0.2	-0.2	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.8	-1.3	-0.6	-0.0	-0.0	-0.1	-0.2	-0.5	-0.7	0.1
Relative age voice broke	1.0	1.6	3.4	-1.8	-0.3	1.1	-0.4	-1.7	-1.9	-0.6	-0.1	1.7
Taking other prescription medications	0.8	1.2	3.2	-0.4	-1.1	0.7	1.8	-1.3	0.3	-0.7	1.8	0.4
Age when periods started (menarche)	3.4	8.1	16.9	3.3	-1.6	-4.1	2.1	-1.1	3.0	-2.9	-1.8	-4.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.4	0.2	-0.2	-0.9	-1.2	1.1	0.3	0.6	-0.6	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	4.4	0.1	-1.8	0.4	1.3	-2.1	-0.4	-1.9	1.8	0.2
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	4.2	-1.2	-1.0	2.1	0.4	-1.3	-1.0	-0.3	1.4	1.2
Qualifications: CSEs or equivalent	1.7	2.3	5.1	1.8	-1.6	-1.1	0.9	-0.4	2.2	-0.5	-1.5	-2.2
Serious illness, injury or assault to yourself	0.3	0.3	0.9	-0.8	-1.0	0.6	-0.8	0.0	0.1	0.3	-0.6	-0.2
High blood pressure	3.3	9.2	16.3	3.5	-2.4	-2.5	3.2	-3.9	3.2	-4.0	0.5	-2.5
Hayfever, allergic rhinitis or eczema	0.3	0.7	3.3	-0.5	-1.8	0.0	0.6	0.8	0.8	0.7	-0.3	-0.9
Multivitamins +/- minerals	0.4	0.5	1.5	-0.5	-1.0	1.2	0.8	-0.7	0.3	0.6	0.5	0.3
Stomach or abdominal pain in last month	0.8	0.9	1.6	-1.3	0.6	1.1	-1.0	1.0	-1.0	1.2	-0.1	1.0
Supplements: Glucosamine	2.1	2.8	6.3	-1.0	-2.5	2.3	1.1	-2.2	-0.3	-1.4	1.0	1.9
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	2.1	-1.1	0.9	1.0	-1.3	0.5	-0.6	1.5	0.3	0.8
Medication: Atenolol	2.1	2.7	6.8	2.6	0.5	-2.4	0.6	-0.5	1.9	-1.8	-0.1	-2.0
Medication: Levothyroxine sodium	1.9	3.2	10.5	1.7	-0.8	1.7	3.2	-2.3	1.0	-1.3	1.9	0.3
Sitting height	5.3	37.5	130.0	6.0	4.0	-11.4	-0.9	0.5	5.4	-3.8	-7.5	-7.4
Chronic bronchitis/emphysema (father)	0.3	0.4	1.2	-1.1	-0.7	0.4	0.6	0.5	0.3	0.7	0.7	-0.0
High blood pressure (mother)	0.9	1.3	6.1	-0.5	-0.0	0.8	-0.8	2.0	-0.4	2.5	-0.3	-0.2
Body mass index (BMI)	2.2	9.4	18.1	2.4	-3.1	-2.3	3.7	-2.0	4.1	-3.3	1.1	-4.2
Impedance of leg (left)	1.7	8.5	21.4	-2.7	0.7	4.6	-0.5	-0.3	-4.0	1.8	2.9	4.4
Leg predicted mass (left)	5.7	30.2	61.7	6.1	-1.6	-7.8	3.2	-2.4	7.2	-5.6	-3.2	-7.9
Trunk fat mass	3.2	13.5	27.1	3.5	-2.7	-3.4	4.3	-2.5	4.5	-4.2	0.9	-5.2
Waist circumference	3.0	11.1	20.0	3.3	-2.8	-2.8	3.8	-2.4	4.2	-3.9	0.3	-4.5
Number of incorrect matches in round	0.4	0.7	1.7	-1.0	-0.5	0.7	0.6	-1.3	-0.5	-1.1	0.7	0.5
Past tobacco smoking	0.9	1.6	7.2	1.4	-0.1	-1.3	0.1	0.5	1.7	0.1	-0.9	-2.7
Alcohol usually taken with meals	1.4	2.3	7.0	-0.9	0.2	2.0	-0.7	-0.1	-2.1	0.6	1.9	2.6
Nervous feelings	0.1	0.2	1.2	-0.3	-0.3	1.1	-0.4	-0.4	0.3	0.7	0.0	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	3.4	-1.6	-0.8	1.8	0.3	-0.6	-0.6	-0.2	1.2	1.7
Hearing difficulty/problems with background noise	1.7	2.7	8.4	-1.7	1.2	2.3	-1.4	-0.2	-1.9	1.0	0.2	2.9
Hair/balding pattern: Pattern 2	0.4	0.5	1.9	1.4	1.1	-0.4	-0.3	-0.3	0.6	0.2	0.5	-0.5
Had menopause	0.8	1.0	3.0	0.6	0.6	-1.7	0.7	-0.5	1.2	-0.8	-0.6	-1.5
Had other major operations	1.5	1.9	5.0	-0.9	0.9	2.1	0.0	-0.4	-0.6	0.7	2.1	2.2
Forced vital capacity (FVC)	3.9	15.1	42.8	3.9	2.4	-6.5	-1.3	1.1	4.1	-1.2	-4.5	-5.5
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.6	6.1	0.5	-2.5	-0.0	1.9	-2.2	0.7	-2.3	1.8	-0.4
Ever unenthusiastic/disinterested for a whole week	0.8	0.9	3.3	-1.8	-0.5	0.6	-0.8	-0.0	-1.0	1.1	-1.2	0.4
Qualifications: None of the above	1.6	3.5	7.4	2.1	-1.2	-2.1	1.1	-1.2	2.4	-1.6	-1.7	-2.7
Financial difficulties in last 2 years	0.5	0.6	2.3	0.2	-1.2	-0.8	-0.5	0.0	0.1	0.1	-1.5	-1.1
Mouth/teeth dental problems	1.6	2.5	8.1	0.1	-0.2	-1.9	-1.8	1.4	0.2	1.9	-2.8	-1.4
Heart attack	0.6	0.8	1.5	-1.2	-0.7	1.2	0.1	-1.0	-0.4	-0.0	1.1	1.2
Allergy	0.8	1.8	5.4	2.3	1.5	-1.2	-0.1	-1.1	-0.2	-2.3	-0.2	0.1
Pain all over the body in last month	0.5	0.5	1.3	0.0	0.3	-0.8	1.0	-0.6	1.2	-0.7	-0.3	-0.6
Diabetes (self-reported)	0.1	0.1	0.6	-0.4	0.3	-0.5	-0.0	-0.0	-0.8	0.0	0.2	0.1
Hayfever/allergic rhinitis (self-reported)	1.7	2.3	7.0	0.8	-1.4	0.5	2.6	-1.0	1.7	-1.5	1.8	-1.0
Medication: Ramipril	0.6	0.7	1.6	1.3	0.3	-0.5	0.4	-1.0	1.1	-1.1	0.7	-0.7
Medication: Simvastatin	1.3	1.9	5.2	-0.6	-1.2	1.4	1.5	-1.6	-0.3	-1.4	2.3	1.2
Fluid intelligence score	0.4	0.8	2.0	-1.3	-0.1	0.5	0.8	0.3	-1.4	0.3	1.3	0.9
Illnesses of siblings	0.1	0.2	0.4	0.0	-0.5	0.6	0.6	0.2	0.2	0.5	0.6	0.0
Neuroticism score	0.8	1.7	4.9	-1.1	-0.2	2.2	-0.3	-1.4	-1.7	-0.2	1.2	1.8
Weight	5.1	24.9	51.6	5.3	-2.4	-6.2	4.2	-2.9	6.5	-5.5	-1.4	-7.2
Impedance of arm (right)	1.9	8.7	17.4	-3.1	1.8	3.3	-2.1	2.6	-4.2	3.7	1.3	3.3
Arm fat percentage (right)	1.1	4.3	9.2	0.9	-2.5	-0.3	3.0	-0.8	2.2	-1.5	2.7	-2.7
Trunk fat-free mass	5.5	31.6	69.7	6.4	-1.0	-8.3	2.5	-2.4	7.3	-5.7	-3.9	-7.7
Hip circumference	2.2	9.6	25.0	3.7	-0.4	-4.5	2.1	-0.5	4.0	-2.6	-0.9	-5.0
Time employed in main current job	1.3	1.5	6.3	2.5	-0.3	-1.1	0.1	-1.0	1.5	-0.9	-0.4	-1.4
Alcohol intake versus 10 years previously	2.9	4.3	6.5	1.7	-1.8	-2.4	1.8	-2.2	2.0	-2.5	-1.3	-2.5
Father’s age at death	0.6	0.7	1.4	0.7	1.2	1.1	1.1	-0.4	0.3	-0.7	0.9	0.9
Worrier / anxious feelings	0.2	0.5	1.6	-0.2	0.5	1.2	-0.7	-0.5	-0.6	0.4	0.2	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	5.4	-1.3	-0.1	2.3	0.8	-0.7	-0.2	0.4	0.5	1.5
Falls in the last year	1.4	1.8	5.4	-2.0	-0.1	1.1	-1.5	1.0	-1.2	2.3	-0.6	1.1
Hair/balding pattern: Pattern 3	0.3	0.5	1.7	0.3	0.7	0.9	0.4	1.3	-0.1	0.9	-0.4	0.6
Number of live births	1.0	1.4	4.7	0.6	-1.1	0.4	1.4	-1.4	0.5	-1.5	2.2	0.3
Forced expiratory volume in 1-second (FEV1)	4.8	16.1	45.7	4.3	1.5	-6.8	-0.6	0.4	4.5	-1.9	-4.4	-6.0
Pulse rate	1.1	1.9	3.9	1.4	-1.2	-0.9	1.7	-2.0	1.2	-1.7	-0.7	-1.2
Happiness	2.9	3.5	9.1	-2.3	1.1	2.7	-0.6	-1.0	-2.3	-0.4	1.4	3.0
Noisy workplace	0.8	0.9	1.2	1.1	-0.8	-1.0	0.8	-1.0	1.0	-0.8	-1.0	-1.1
Qualifications: A levels/AS levels or equivalent	1.7	3.8	9.7	-1.8	1.8	0.6	-2.1	2.9	-1.8	3.1	-0.2	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.5	-0.3	-0.1	0.1	-0.7	1.2	0.4	1.2	-1.2	-0.6
Mouth/teeth dental problems: Dentures	1.0	1.8	6.2	0.9	-1.0	1.0	2.5	-1.0	1.3	-1.5	1.3	-0.6
Asthma	1.2	2.3	7.5	-2.7	-1.2	2.3	-0.4	0.1	-0.8	1.9	0.7	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.1	-1.5	-0.7	0.5	0.0	-0.6	-0.6	-0.4	-0.3	0.6
Medication: Cholesterol lowering	0.2	0.4	0.9	-0.3	0.9	-0.3	-1.0	0.5	-0.6	0.1	0.0	0.7
Depression (self-reported)	0.2	0.3	0.6	-0.0	-0.7	-0.4	0.2	-0.4	0.7	-0.3	-0.8	-0.5
Medication: Lansoprazole	1.1	1.3	2.6	0.9	-1.6	-0.7	1.1	-1.5	1.4	-1.2	0.2	-0.8
Prospective memory result	1.4	1.7	5.2	2.3	0.6	-0.8	0.7	-0.9	1.8	-1.6	0.2	-1.3
Lung cancer (father)	0.8	0.9	3.6	-0.1	-1.9	0.6	0.7	-1.5	0.2	-1.1	-0.5	-0.2
Illnesses of mother	1.2	1.5	4.3	1.9	-0.4	-0.8	0.4	-1.2	2.1	-1.7	-0.6	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	4.5	14.2	40.3	3.8	1.3	-6.3	-0.5	1.0	4.3	-1.6	-4.0	-5.7
Pulse wave Arterial Stiffness index	1.5	1.8	4.5	2.1	-0.8	-0.6	1.2	-1.6	1.5	-1.4	-1.2	-0.9
Impedance of arm (left)	2.0	9.1	19.1	-3.3	1.6	3.5	-2.1	2.3	-4.4	3.9	0.9	3.4
Arm fat mass (right)	2.6	10.9	25.2	3.1	-2.6	-3.0	3.7	-1.5	4.5	-3.2	1.0	-5.0
Trunk predicted mass	5.5	31.3	69.1	6.3	-1.1	-8.3	2.5	-2.5	7.3	-5.7	-3.9	-7.6
Standing height	3.5	34.7	92.4	7.2	1.2	-9.6	1.6	-2.4	6.4	-5.5	-5.6	-7.5
Length of working week for main job	3.2	3.5	9.9	-0.8	2.5	-1.8	-2.3	3.1	0.4	2.3	-0.8	-0.6
Exposure to tobacco smoke at home	0.6	0.7	2.4	-0.7	-0.5	-0.3	-1.2	-1.0	-0.4	-0.3	-1.5	0.2
Breastfed as a baby	0.8	1.0	4.3	-0.6	0.7	-1.6	-1.1	-0.1	-0.2	-0.4	-2.1	0.2
Tense / ‘highly strung’	1.6	2.6	7.1	-0.2	-1.0	1.6	1.5	-2.7	0.3	-1.6	2.5	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	1.9	-1.4	0.0	1.3	-0.5	-0.5	-1.3	0.2	-0.3	1.2
Hair/balding pattern: Pattern 4	0.6	1.4	5.2	-0.8	-0.9	0.9	0.5	-2.3	-0.7	-1.4	1.0	1.1
Birth weight of first child	2.6	4.8	15.5	1.8	-1.5	-1.6	3.9	-2.2	1.3	-2.7	0.4	-2.3
Peak expiratory flow (PEF)	4.2	9.9	32.3	3.0	2.7	-5.7	-2.0	1.4	2.6	-0.1	-3.7	-3.7
Pulse wave reflection index	0.2	0.2	0.8	-0.1	-0.3	-0.1	-0.7	0.3	-0.5	0.4	-0.9	-0.1
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.8	-1.4	0.7	0.3	-0.4	-0.5	-0.6	-0.0	-0.5	0.3
Loud music exposure frequency	0.1	0.1	0.5	-0.1	0.7	-0.5	-0.0	0.1	0.0	-0.4	-0.6	0.3
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.5	1.6	-0.8	-0.3	1.1	-0.3	0.8	-0.5	0.6	-0.6
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	5.6	-1.3	0.8	1.4	-0.5	-0.5	-1.9	-0.7	0.8	2.4
Blood clot in the leg (DVT)	0.8	1.0	1.5	-1.2	1.2	0.7	-0.8	0.9	-0.1	1.2	1.0	1.2
Medication: Paracetamol	1.3	2.2	5.1	1.0	-1.3	-0.7	2.1	-0.7	2.3	-1.2	0.9	-2.2
Headache pain in last month	0.2	0.4	1.3	-1.1	0.3	-0.0	-0.4	0.7	-0.3	0.9	-0.3	0.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	3.3	-1.1	-0.8	1.0	-0.5	1.2	-0.5	1.8	-0.1	-0.1
Glaucoma (self-reported)	1.2	1.4	5.7	-1.0	1.1	-0.7	-2.4	0.2	-1.0	0.5	-1.4	0.7
Gout (self-reported)	0.1	0.2	0.9	0.2	0.2	-0.3	-0.4	-0.1	0.0	0.2	-0.3	-0.9
Hypothyroidism/myxoedema (self-reported)	2.1	4.1	9.7	0.9	-1.5	2.5	3.0	-3.1	0.2	-1.6	2.2	1.0
Medication: Amlodipine	0.9	1.3	2.3	0.8	-0.2	-1.3	1.5	-0.7	1.4	-1.5	0.1	-1.3
Medication: Ventolin 100micrograms inhaler	1.1	1.4	4.4	-1.4	-1.2	2.1	-0.0	1.1	-0.7	1.6	0.1	0.5
Birth weight	4.4	9.6	17.2	4.1	1.1	-4.1	3.2	-2.3	3.3	-3.7	-1.5	-3.0
Chronic bronchitis/emphysema (mother)	1.4	1.6	3.5	-1.9	0.0	-1.6	-1.1	1.6	-1.2	1.6	-0.8	-0.3
High blood pressure (siblings)	0.4	0.6	1.8	0.8	0.8	-1.3	-0.8	0.2	0.2	-0.3	-1.2	-0.5
Forced vital capacity (FVC), Best measure	3.4	12.3	35.4	3.4	1.9	-6.0	-0.9	1.4	3.8	-0.9	-3.7	-5.3
Body fat percentage	1.6	6.5	14.4	1.5	-2.8	-0.6	3.8	-2.2	2.6	-2.7	2.5	-2.9
Leg fat percentage (right)	2.3	8.2	19.1	1.7	-3.3	-0.1	4.4	-2.9	2.9	-3.0	2.9	-2.6
Arm fat-free mass (right)	6.2	31.5	59.8	6.2	-1.7	-7.7	3.2	-3.4	7.4	-6.1	-3.4	-7.6
Exposure to tobacco smoke outside home	0.8	1.1	4.3	0.3	-1.8	0.4	-0.3	-2.1	-0.4	-0.7	-1.0	0.1
Comparative body size at age 10	0.2	0.4	1.3	-0.7	-1.1	-0.3	0.4	0.6	0.8	0.1	-0.4	-0.9
Number of full brothers	0.2	0.3	0.8	-0.9	-0.7	0.1	0.2	-0.3	0.3	-0.2	-0.9	0.3
Worry too long after embarrassment	2.6	4.3	13.2	-2.2	0.8	1.8	-2.0	1.0	-3.6	2.4	-0.7	2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	2.2	-1.5	-0.4	0.1	-0.4	-0.3	-0.3	0.0	0.4	0.5
Wheeze or whistling in the chest in last year	2.3	4.2	11.1	-3.3	-1.9	3.3	0.1	0.4	-1.6	2.0	1.8	1.3
Number of children fathered	0.8	0.9	3.8	0.3	-0.3	-2.0	-0.3	-0.4	-0.1	-1.3	-1.3	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.3	-0.5	0.2	0.3	-0.3	-0.4	-0.9	-0.7	-0.4	1.1
Age at first live birth	3.4	6.1	13.4	-3.0	1.6	2.9	-0.8	0.8	-3.7	1.1	2.4	3.6
Pulse wave peak to peak time	0.9	1.1	2.7	-1.6	0.8	-0.0	-1.0	1.5	-1.0	1.0	0.9	0.4
Health satisfaction	1.3	1.7	4.1	-2.0	-1.1	2.0	-0.1	-0.5	-1.6	0.6	0.8	1.3
Shortness of breath walking on level ground	1.4	1.7	5.8	-1.8	-0.3	1.1	-1.2	1.3	-0.7	2.4	-1.0	-0.5
Qualifications: College or University degree	2.9	9.3	16.3	-3.1	4.0	1.6	-2.9	2.9	-4.0	2.8	0.8	3.6
Eye problems/disorders: None of the above	0.7	0.8	2.4	0.1	-1.6	1.1	1.1	-0.7	0.3	-0.9	0.1	0.8
Mouth/teeth dental problems: Loose teeth	1.0	1.2	4.3	-0.3	0.7	2.1	0.9	-0.3	-1.0	-0.3	1.5	1.3
Emphysema/chronic bronchitis	0.1	0.1	0.4	-0.6	-0.2	-0.3	0.5	-0.6	0.2	0.0	0.1	-0.3
Medication for pain relief, constipation, heartburn	0.6	1.0	2.8	-0.5	0.9	0.8	-1.7	0.4	-1.2	1.2	-0.5	1.2
Neck or shoulder pain in last month	0.4	0.6	2.5	-0.8	-0.4	0.5	0.3	-1.6	-0.5	-0.7	-0.3	0.8
Medication: Blood pressure	1.0	1.8	5.3	1.7	0.6	-1.5	1.3	-1.4	0.9	-2.3	0.6	-0.6
Angina (self-reported)	0.6	0.7	1.9	-0.4	1.3	0.5	-1.0	1.4	-0.1	0.5	1.1	0.6
Migraine (self-reported)	0.3	0.3	1.3	-0.5	1.1	-0.4	-0.3	0.2	-0.7	-0.1	0.7	0.4
Medication: Ibuprofen	0.3	0.4	1.5	-1.2	-0.7	0.4	0.4	-0.6	-0.4	-0.5	0.0	0.6
Medication: Allopurinol	0.2	0.3	0.8	-0.1	-0.0	-0.5	-0.9	-0.1	-0.4	0.3	-0.6	-0.9
Medication: Omeprazole	1.7	2.0	4.9	1.0	-2.2	-0.1	1.9	-1.0	1.7	-1.8	0.2	-1.1
Medication: Seretide 50 evohaler	0.6	0.7	1.7	-0.3	-0.4	-1.1	-0.2	1.2	0.5	1.1	-0.5	-1.3
Mean time to correctly identify matches	0.5	1.0	3.0	-1.7	-0.4	1.3	0.0	0.2	-1.7	0.6	0.8	0.5
Heart disease (mother)	1.0	1.2	2.5	-1.6	-0.1	1.2	0.4	-1.1	-1.4	-0.6	0.9	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.3	2.7	6.7	-2.6	-0.5	2.1	-0.9	0.5	-2.3	1.2	-0.1	2.2
Whole body fat mass	3.0	12.6	23.6	3.3	-2.6	-3.0	4.3	-2.6	4.4	-4.1	1.1	-4.9
Leg fat mass (right)	3.7	14.4	23.0	3.6	-3.0	-2.8	4.7	-3.1	4.7	-4.5	1.4	-4.8
Arm predicted mass (right)	6.2	31.6	59.0	6.3	-1.7	-7.7	3.2	-3.3	7.5	-6.0	-3.3	-7.6
Pulse rate, automated reading	0.6	2.0	4.5	1.4	-1.2	-0.2	2.1	-1.9	1.3	-1.6	1.0	-0.9
Alcohol intake frequency.	3.2	7.3	19.5	2.2	-2.3	-4.0	0.8	0.1	3.8	-1.2	-2.1	-4.4
Comparative height size at age 10	2.1	11.5	27.9	4.2	0.5	-5.3	0.8	-1.2	4.0	-3.1	-3.3	-4.3
Number of full sisters	0.7	0.9	3.3	-0.5	0.2	-0.6	-0.9	1.8	-1.2	0.8	-1.0	-0.3
Suffer from ‘nerves’	0.3	0.5	1.6	0.2	-0.5	-0.4	-0.2	-0.8	0.9	-0.6	-1.3	-0.9
Overall health rating	0.3	0.7	2.7	-1.6	-0.9	0.3	-0.1	0.5	-1.0	0.9	-0.7	-0.2
Chest pain or discomfort	1.9	2.8	9.5	-3.1	-0.6	2.1	-0.6	0.6	-1.9	1.2	1.1	1.9
Had major operations	1.6	1.8	4.5	1.3	1.3	-2.1	-0.2	1.6	0.8	0.1	-1.9	-1.4
Age at last live birth	2.6	3.7	7.5	-2.4	1.2	2.4	-0.9	0.9	-2.7	1.4	1.4	2.7
Family relationship satisfaction	3.6	4.5	10.8	-3.0	0.8	3.1	-0.5	-0.1	-2.5	0.9	1.7	3.3
Leg pain on walking	0.6	0.7	2.4	-1.3	-0.7	0.8	-0.4	0.9	-0.2	1.6	-0.3	-0.5
Qualifications: NVQ or HND or HNC or equivalent	2.8	3.3	7.7	2.8	-1.3	-0.7	2.7	-1.0	1.9	-2.1	1.0	-1.7
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.6	0.8	0.0	-0.5	0.7	-0.2	0.0	-1.3	1.9	-0.0
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	2.7	1.0	0.8	-0.4	1.1	-1.6	0.5	-1.6	1.5	0.4
Medication: Aspirin	0.6	0.7	1.8	0.7	-0.2	-0.2	1.2	-0.9	0.7	-1.4	1.2	-0.2
Supplements: Vitamin C	1.2	1.5	4.1	1.7	-0.1	-1.1	0.7	-2.0	0.8	-1.8	0.6	-0.3
Knee pain experienced in last month	1.2	1.8	3.8	0.9	-1.7	-1.1	1.7	-1.5	0.6	-2.0	-0.9	-1.1
Hypertension (Self-reported)	3.7	10.2	18.6	3.8	-2.2	-2.8	3.3	-3.9	3.6	-4.3	0.7	-2.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	4.1	0.0	-2.0	-0.3	1.6	-0.4	0.5	-0.9	-0.7	-0.8
Illnesses of father: Heart disease	1.0	1.4	2.8	-0.9	1.0	1.6	-0.6	0.5	-1.7	1.1	0.9	1.5
Illnesses of siblings: Diabetes	0.9	1.1	3.7	0.3	0.8	-1.9	-0.1	0.9	0.7	0.1	-1.3	-1.7
Smoking status: Previous	0.8	1.2	4.2	-1.0	-0.3	1.1	0.2	-0.5	-1.4	-0.3	1.3	2.1
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.6	9.8	1.2	0.8	-3.1	0.2	-0.9	1.3	-1.7	-1.8	-1.7
Whole body fat-free mass	5.7	32.5	69.6	6.4	-1.3	-8.3	2.7	-2.5	7.5	-5.8	-3.8	-8.0
Leg fat-free mass (right)	5.6	29.8	65.9	6.0	-1.1	-8.1	2.6	-2.0	7.2	-5.3	-3.6	-7.9
Arm fat percentage (left)	1.0	4.1	8.8	0.9	-2.5	-0.4	3.0	-0.9	2.2	-1.4	2.3	-2.8
Average weekly red wine intake	0.4	0.6	1.8	-0.2	1.1	0.6	0.1	0.0	-0.6	-0.4	1.3	1.4
Handedness (chirality/laterality): Left-handed	1.7	2.1	5.7	1.7	-0.6	-2.1	0.8	0.4	1.6	-0.7	-1.2	-2.4
Mood swings	0.7	1.3	3.0	-1.5	-0.1	1.7	-0.9	0.2	-1.7	1.3	-0.1	0.9
Loneliness, isolation	0.4	0.5	1.3	-0.9	0.1	0.7	-0.9	-1.2	-0.6	-0.7	-0.1	0.4
Long-standing illness, disability or infirmity	0.6	0.9	3.6	-1.9	-1.1	0.9	-0.1	-0.9	-0.3	0.5	0.7	0.8
Ever had bowel cancer screening	2.5	3.0	6.5	-2.5	-1.4	2.4	-0.5	-0.9	-2.1	0.2	1.5	2.2
Diabetes diagnosed by doctor	0.2	0.3	1.0	-0.7	0.3	-1.0	-0.7	0.2	-0.7	0.3	-0.4	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.6	0.1	-0.5	0.7	0.3	0.4	0.4	0.7	0.2	-0.1
Friendships satisfaction	6.8	8.4	17.2	-4.2	2.8	2.8	-1.6	1.5	-3.9	1.9	1.6	4.0
Qualifications: nursing, teaching	4.8	7.4	16.0	-3.3	2.8	1.0	-3.0	2.5	-4.0	2.7	0.3	2.9
Commuting to job workplace: Walk	0.6	0.6	3.1	0.2	1.8	-0.1	-0.6	0.7	-0.4	0.7	-0.9	0.3
Eye problems/disorders: Cataract	0.2	0.2	0.8	-0.4	0.9	0.4	-0.5	-0.1	-0.4	0.4	0.6	0.4
Mouth/teeth dental problems: Mouth ulcers	2.0	3.1	5.3	2.0	-1.0	-0.7	2.3	-1.4	2.1	-2.2	2.1	-1.3
Medication for cholesterol	0.9	1.4	2.7	0.4	1.5	-0.4	-1.5	1.6	-0.9	1.3	-1.6	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	3.3	-1.7	-1.6	1.8	-0.0	-0.1	-1.3	1.1	0.5	1.1
Back pain experienced in last month	1.5	2.2	6.4	-1.5	-2.5	2.0	1.3	-0.4	-1.1	-1.0	1.3	1.1
Mineral and other dietary supplements	2.0	2.8	7.4	-0.8	2.1	-1.5	-1.8	2.7	-1.1	1.8	-1.2	-0.9
Breast cancer (self-reported)	0.4	0.5	1.9	-0.1	-1.4	-0.4	1.2	-0.2	0.6	-0.0	0.5	-0.8
Asthma (self-reported)	1.0	2.0	6.7	-2.6	-1.6	2.0	-0.1	-0.0	-0.5	1.8	0.6	0.8
Osteoporosis (self-reported)	1.4	1.7	5.1	2.2	0.1	0.0	1.6	-1.1	1.4	-1.1	1.7	-0.6
Osteoarthritis (self-reported)	0.8	1.1	2.4	-1.3	-1.3	0.8	0.4	-1.2	-0.1	-1.0	1.5	0.7
Medication: Aspirin	0.7	0.9	2.5	0.5	-0.2	-0.2	1.2	-1.0	0.6	-1.5	1.6	-0.2
Medication: Gliclazide	0.8	0.9	3.1	0.1	0.4	-1.6	-0.7	0.4	-0.3	0.8	-1.8	-0.9
Illnesses of father: None of the above (group 1)	0.5	0.6	1.8	0.4	-1.1	-0.1	0.2	-1.3	-0.1	-1.0	-0.7	-0.3
Smoking status: Current	0.3	0.4	1.7	-0.8	-0.3	0.2	-0.2	0.6	-0.1	1.3	-1.0	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.2	9.6	1.9	1.7	-3.1	-0.7	1.8	2.3	-0.0	-1.8	-3.1
Whole body water mass	5.7	32.5	69.9	6.4	-1.4	-8.4	2.7	-2.4	7.5	-5.7	-3.8	-8.0
Leg predicted mass (right)	5.5	29.3	64.7	5.9	-1.2	-8.0	2.6	-1.9	7.1	-5.3	-3.6	-7.8
Arm fat mass (left)	2.6	10.5	23.8	3.0	-2.6	-3.0	3.6	-1.8	4.3	-3.2	0.8	-4.9
Number of self-reported non-cancer illnesses	1.6	2.7	10.9	-0.7	-1.6	1.2	0.9	-3.3	0.6	-1.9	1.7	1.3
Average weekly champagne plus white wine intake	0.6	0.9	2.8	-0.7	-0.1	-0.1	0.4	-0.3	-1.0	-1.3	1.2	1.7
Miserableness	0.4	0.7	1.4	-1.0	-0.6	0.8	-0.9	-0.4	-1.2	0.7	-0.8	0.6
Guilty feelings	2.2	3.2	9.6	-1.7	-0.1	2.9	-1.2	-0.0	-2.2	0.5	1.4	3.1
Wears glasses or contact lenses	0.2	0.2	1.3	0.4	-0.0	-0.0	0.2	0.0	0.7	-0.3	-1.1	-0.3
Ever taken oral contraceptive pill	1.3	1.4	5.8	-0.8	-0.6	2.4	0.2	-0.0	-1.4	1.0	1.1	1.3
Hearing aid user	1.5	1.7	3.9	-0.0	-0.8	1.7	1.6	-2.0	-0.6	-1.0	1.4	1.5
Mother’s age at death	0.7	0.9	2.4	-1.1	0.8	0.9	-0.6	0.2	-1.1	0.3	1.2	1.6
Financial situation satisfaction	0.1	0.2	0.4	-0.2	0.6	0.5	-0.2	-0.4	-0.2	-0.6	-0.0	0.3
Tinnitus: Yes, now most or all of the time	1.2	1.4	2.6	-1.2	1.0	0.4	-1.6	0.4	-1.5	1.0	-1.6	1.4
Commuting to job workplace: Public transport	0.3	0.3	1.1	-1.0	-0.2	0.8	-0.0	-0.0	-0.6	0.3	0.6	0.4
Eye problems/disorders: Glaucoma	1.1	1.2	4.2	-0.9	1.1	-0.3	-2.1	0.6	-1.5	1.0	-0.9	0.5
Medication: Blood pressure	1.6	3.1	6.6	1.4	-1.8	-1.7	1.7	-1.5	2.6	-1.9	0.9	-2.0
Pain type(s) experienced in last month: Hip pain	1.3	1.7	4.4	-1.9	-0.6	2.1	0.5	0.2	-1.5	0.8	1.7	1.0
Supplements: Fish oil (including cod liver oil)	2.0	2.6	6.2	1.8	-1.0	0.9	2.0	-2.5	1.8	-2.1	1.1	0.0
High cholesterol (Self-reported)	1.0	1.9	7.1	0.3	-1.6	0.6	1.0	-2.7	0.9	-1.6	1.4	0.3
Medication: Bendroflumethiazide	1.1	1.6	4.2	1.2	0.5	-1.9	1.1	-0.7	1.4	-1.3	-0.3	-2.0
Medication: Paracetamol	0.9	1.4	4.6	0.8	-0.5	-0.7	1.6	0.2	1.7	-0.5	1.1	-2.2
Medication: Lisinopril	0.2	0.3	0.8	-0.9	-0.7	0.5	0.3	0.0	-0.8	0.1	0.1	0.7
Medication: Atorvastatin	1.2	1.5	5.6	-1.1	0.3	-1.2	-2.4	0.8	-0.2	1.2	-1.6	-0.7
Illnesses of father: High blood pressure	0.8	1.0	2.3	1.1	-1.4	0.4	0.8	-1.5	1.3	-0.8	-0.1	-0.1
Alcohol drinker status: Never	1.4	1.7	3.3	1.4	-1.8	-1.0	0.9	-0.3	1.7	-1.6	0.9	-1.4
Ever smoked	0.3	0.5	2.5	-0.3	0.4	0.4	-0.1	-0.5	-0.8	-0.3	0.5	1.6
Basal metabolic rate	5.8	32.0	63.8	6.4	-1.8	-8.0	3.3	-2.7	7.5	-5.8	-3.1	-8.0
Leg fat percentage (left)	2.0	7.1	16.3	1.4	-3.0	-0.2	4.0	-2.8	2.7	-3.0	2.7	-2.4
Arm fat-free mass (left)	5.9	29.7	56.4	6.1	-1.8	-7.5	3.2	-3.1	7.2	-6.0	-2.9	-7.4
Number of operations (self-reported)	0.1	0.2	0.6	0.0	-0.1	0.8	0.7	-0.7	-0.1	-0.4	-0.1	0.5
Average weekly beer plus cider intake	0.5	0.8	2.3	1.5	0.9	-0.8	1.0	0.3	0.7	-0.3	0.1	-1.2
Irritability	1.6	2.8	6.5	-1.2	0.8	2.1	0.4	-1.0	-2.0	-0.6	2.5	2.5
Risk taking	0.2	0.3	1.0	-0.7	-0.0	-0.5	-0.2	0.3	-1.0	-0.8	0.8	0.2
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.3	-0.5	-0.3	-0.4	0.2	-0.2	-0.5	-0.4	-0.0	-0.1
Fractured/broken bones in last 5 years	1.8	2.3	7.1	-2.2	-0.4	1.3	-1.5	1.9	-0.8	2.7	0.3	0.4
Age started oral contraceptive pill	0.3	0.4	1.0	-0.4	1.0	0.5	-0.4	-0.4	-1.0	0.5	0.2	0.6
Diastolic blood pressure, automated reading	4.2	12.9	26.8	5.2	-2.6	-2.0	3.4	-4.0	4.7	-3.8	0.7	-3.8
Ever depressed for a whole week	1.0	1.3	3.0	-1.7	-0.7	1.0	-1.2	-0.9	-1.5	0.4	-1.2	1.0
Unable to work because of sickness or disability	1.5	2.0	6.6	-1.9	0.9	0.7	-1.7	1.3	-1.0	2.6	-0.3	0.6
Commuting to job workplace: Cycle	0.3	0.4	2.0	-0.6	-0.3	1.4	-0.2	-0.4	-0.1	0.7	-0.2	0.3
Myopia	1.7	2.4	5.0	1.8	-1.8	-1.3	1.8	-0.6	2.2	-1.4	0.2	-1.9
Vascular/heart problems diagnosed by doctor	2.7	7.2	12.2	-3.2	2.2	2.0	-3.0	3.5	-2.9	3.3	-0.7	2.3
Cholesterol lowering medication	2.8	4.2	10.2	0.7	-2.4	0.3	2.5	-3.2	1.9	-2.6	2.0	-0.8
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	3.7	1.2	-1.8	-0.1	1.9	-0.4	1.5	-1.5	0.0	-1.4
Pain experienced in last month	0.6	0.9	2.5	-0.0	1.6	-0.4	-1.5	1.4	-0.1	1.3	0.2	-0.1
Supplements: Calcium	0.5	0.6	1.4	-0.9	-1.1	-0.2	-0.2	-1.0	-1.2	-0.2	-0.5	0.7
Basal cell carcinoma (self-reported)	0.8	0.9	2.1	0.2	0.4	-1.4	-0.6	0.7	1.3	0.3	-1.4	-1.2
Heart attack/myocardial infarction (self-reported)	0.4	0.6	1.2	-1.1	-0.7	1.0	0.1	-0.9	-0.3	0.1	0.9	0.9
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	1.5	-0.8	1.2	0.5	-0.6	0.6	0.3	0.8	1.1	1.0
Heart disease (siblings)	1.7	2.1	6.0	0.0	-1.5	1.2	1.5	-2.4	0.7	-2.5	0.8	0.6
Alcohol drinker status: Previous	1.1	1.3	3.0	-1.7	0.9	-0.5	-1.7	0.3	-0.7	1.0	-1.0	1.3
Pack years of smoking	2.2	3.2	6.9	2.5	-1.2	-0.3	2.6	-0.9	2.6	-1.1	0.1	-2.3
Impedance of whole body	2.1	10.5	22.3	-3.4	1.3	4.5	-1.7	1.3	-4.7	3.5	1.8	4.3
Leg fat mass (left)	3.6	14.1	23.1	3.5	-2.9	-2.9	4.6	-3.0	4.7	-4.5	1.3	-4.8
Arm predicted mass (left)	5.9	29.8	54.2	6.0	-2.1	-7.4	3.3	-3.2	7.3	-6.1	-2.8	-7.3