[Hub]/) : Traits : Blood White Count : ← →

chr6:129,638,583-131,163,098

Best TWAS P=9.09e-13 · Best GWAS P=2.48e-11 conditioned to 0.232

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	L3MBTL3	0.20	0.08	lasso	4	0.09	1.1e-07	-6.5	-6.5	9.4e-11	0.67	0.01	0.99	FALSE
2	GTEx	Adipose Visceral Omentum	L3MBTL3	0.14	0.12	lasso	2	0.15	2.8e-08	-6.5	-6.8	1.0e-11	0.68	0.01	0.99	FALSE
3	GTEx	Breast Mammary Tissue	L3MBTL3	0.31	0.25	lasso	7	0.23	2.8e-12	-6.5	-6.7	1.7e-11	0.69	0.01	0.99	FALSE
4	GTEx	Breast Mammary Tissue	RP11-73O6.3	0.27	0.22	lasso	9	0.22	1.5e-11	-6.5	-7.0	3.2e-12	0.76	0.00	1.00	FALSE
5	GTEx	Breast Mammary Tissue (Male)	L3MBTL3	0.31	0.24	lasso	6	0.23	5.5e-06	-6.5	-6.3	2.5e-10	0.66	0.02	0.93	FALSE
6	GTEx	Breast Mammary Tissue (Male)	RP11-73O6.3	0.33	0.17	lasso	4	0.12	1.3e-03	-6.5	-7.1	1.7e-12	0.65	0.02	0.89	FALSE
7	GTEx	Breast Mammary Tissue (Female)	L3MBTL3	0.30	0.13	lasso	5	0.14	4.5e-05	-5.2	-6.9	7.0e-12	0.73	0.02	0.96	FALSE
8	GTEx	Breast Mammary Tissue (Female)	RP11-73O6.3	0.29	0.08	lasso	5	0.10	5.7e-04	-6.6	-7.1	9.1e-13	0.84	0.01	0.97	TRUE
9	GTEx	Cells EBV-transformed lymphocytes	L3MBTL3	0.28	0.08	lasso	10	0.03	4.4e-02	-6.5	-6.8	8.6e-12	0.73	0.02	0.92	FALSE
10	GTEx	Colon Transverse	L3MBTL3	0.27	0.13	lasso	8	0.20	8.0e-10	-6.5	-6.9	5.3e-12	0.83	0.01	0.99	FALSE
11	GTEx	Colon Transverse	RP11-73O6.3	0.19	0.09	lasso	2	0.06	1.2e-03	-6.5	-6.6	3.4e-11	0.65	0.01	0.98	FALSE
12	GTEx	Esophagus Mucosa	L3MBTL3	0.26	0.18	lasso	2	0.23	2.7e-15	-6.6	-7.1	1.5e-12	0.83	0.00	1.00	FALSE
13	GTEx	Lung	L3MBTL3	0.37	0.34	lasso	4	0.38	4.1e-30	-6.5	-6.8	1.3e-11	0.70	0.00	1.00	FALSE
14	GTEx	Lung	RP11-73O6.3	0.15	0.08	lasso	5	0.12	2.2e-09	-6.5	-6.7	2.3e-11	0.69	0.02	0.98	FALSE
15	GTEx	Nerve Tibial	L3MBTL3	0.30	0.23	lasso	4	0.22	2.3e-15	-6.5	-6.8	1.3e-11	0.69	0.00	1.00	FALSE
16	GTEx	Pancreas	L3MBTL3	0.32	0.17	lasso	4	0.23	4.4e-10	-6.5	-6.8	1.1e-11	0.68	0.00	1.00	FALSE
17	GTEx	Pituitary	L3MBTL3	0.45	0.31	lasso	8	0.29	5.1e-08	-5.2	-6.2	4.7e-10	0.70	0.02	0.98	FALSE
18	GTEx	Pituitary	RP11-73O6.3	0.48	0.07	lasso	7	0.16	8.2e-05	-5.2	-5.3	9.2e-08	0.49	0.03	0.93	FALSE
19	GTEx	Prostate	L3MBTL3	0.35	0.27	lasso	5	0.17	5.9e-05	-6.5	-6.5	8.5e-11	0.65	0.01	0.96	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	L3MBTL3	0.26	0.12	lasso	4	0.12	4.0e-07	-6.5	-7.1	1.1e-12	0.87	0.01	0.99	FALSE
21	GTEx	Skin Sun Exposed Lower leg	L3MBTL3	0.25	0.25	lasso	9	0.24	1.4e-19	-6.5	-6.5	5.9e-11	0.71	0.00	1.00	FALSE
22	GTEx	Small Intestine Terminal Ileum	L3MBTL3	0.37	0.20	lasso	4	0.17	1.3e-04	-6.5	-6.8	1.2e-11	0.70	0.01	0.93	FALSE
23	GTEx	Spleen	L3MBTL3	0.64	0.34	enet	14	0.48	6.4e-14	-6.6	-7.0	3.0e-12	0.82	0.00	1.00	FALSE
24	GTEx	Spleen	RP11-73O6.3	0.45	0.43	enet	21	0.42	7.7e-12	-6.6	-6.7	2.3e-11	0.82	0.00	1.00	FALSE
25	GTEx	Stomach	L3MBTL3	0.36	0.18	enet	27	0.20	1.1e-09	-6.2	-6.7	2.5e-11	0.70	0.04	0.96	FALSE
26	GTEx	Stomach	RP11-73O6.3	0.21	0.12	lasso	6	0.06	5.9e-04	-6.2	-5.5	3.1e-08	0.65	0.06	0.79	FALSE
27	GTEx	Testis	L3MBTL3	0.41	0.22	lasso	8	0.30	9.2e-14	-6.5	-6.7	2.2e-11	0.62	0.00	1.00	FALSE
28	GTEx	Thyroid	L3MBTL3	0.40	0.39	enet	9	0.43	2.8e-35	-6.5	-7.1	1.4e-12	0.77	0.00	1.00	FALSE
29	GTEx	Thyroid	RP11-73O6.3	0.18	0.15	lasso	3	0.20	2.3e-15	-5.6	-6.7	2.0e-11	0.68	0.02	0.98	FALSE
30	GTEx	Whole Blood	L3MBTL3	0.22	0.20	lasso	9	0.20	5.1e-18	-6.5	-7.0	3.2e-12	0.70	0.00	1.00	FALSE
31	GTEx	Whole Blood	RP11-73O6.3	0.15	0.06	lasso	8	0.04	1.1e-04	-6.5	-7.1	1.5e-12	0.65	0.01	0.98	FALSE
32	METSIM	Adipose	L3MBTL3	0.13	0.12	enet	22	0.12	4.8e-18	-6.6	-5.7	1.4e-08	0.82	0.00	1.00	FALSE
33	ROSMAP	Brain Pre-frontal Cortex	L3MBTL3	0.14	0.07	blup	609	0.08	3.8e-10	-6.5	-5.7	1.2e-08	0.64	0.01	0.99	FALSE