Best TWAS P=1.32e-18 · Best GWAS P=1.51e-19 conditioned to 0.0207
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CENPW | 0.04 | 0.06 | lasso | 10 | 0.06 | 2.4e-07 | -8.7 | 8.8 | 1.3e-18 | -0.93 | 0.06 | 0.94 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | CENPW | 0.17 | 0.01 | enet | 15 | 0.06 | 1.8e-03 | -8.5 | 7.0 | 2.1e-12 | -0.67 | 0.04 | 0.37 | FALSE |
| 3 | METSIM | Adipose | CENPW | 0.02 | 0.02 | blup | 189 | 0.01 | 8.3e-03 | -8.5 | 6.0 | 1.8e-09 | -0.71 | 0.04 | 0.54 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CENPW | 0.04 | 0.05 | lasso | 5 | 0.05 | 2.6e-06 | -8.7 | 8.3 | 7.3e-17 | -0.90 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CENPW | 0.04 | 0.06 | blup | 35 | 0.05 | 9.2e-07 | -8.6 | 8.3 | 1.4e-16 | -0.90 | 0.02 | 0.98 | FALSE |