TWAS
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About
Usage
Models
Genes
Traits
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Traits
:
Blood White Count
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chr7:128,773,770-131,315,092
Best TWAS P=3.26e-11 · Best GWAS P=2.4e-27 conditioned to 2.33e-15
129M
129.5M
130M
130.5M
131M
0
5
10
15
20
25
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Glioblastoma Multiforme
FLJ43663
0.25
0.00
blup
55
0.03
3.4e-02
-0.39
-6.6
3.3e-11
-0.65
0.01
0.26
TRUE
2
METSIM
Adipose
RP11-138A9.1
0.07
0.01
bslmm
394
0.02
8.1e-04
-1.23
-5.8
8.9e-09
-0.25
0.35
0.08
TRUE
1
GTEx
Whole Blood
UBE2H
0.08
0.04
enet
10
0.04
1.5e-04
5.68
5.6
2.5e-08
0.05
0.00
0.99
TRUE
3
YFS
Blood
UBE2H
0.03
0.02
lasso
6
0.02
3.6e-07
5.19
5.2
1.7e-07
0.06
0.01
0.99
FALSE