Best TWAS P=3.26e-11 · Best GWAS P=2.4e-27 conditioned to 2.33e-15
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | UBE2H | 0.08 | 0.04 | enet | 10 | 0.04 | 1.5e-04 | 5.68 | 5.6 | 2.5e-08 | 0.05 | 0.00 | 0.99 | TRUE |
| 2 | METSIM | Adipose | RP11-138A9.1 | 0.07 | 0.01 | bslmm | 394 | 0.02 | 8.1e-04 | -1.23 | -5.8 | 8.9e-09 | -0.25 | 0.35 | 0.08 | TRUE |
| 3 | YFS | Blood | UBE2H | 0.03 | 0.02 | lasso | 6 | 0.02 | 3.6e-07 | 5.19 | 5.2 | 1.7e-07 | 0.06 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | FLJ43663 | 0.25 | 0.00 | blup | 55 | 0.03 | 3.4e-02 | -0.39 | -6.6 | 3.3e-11 | -0.65 | 0.01 | 0.26 | TRUE |