Best TWAS P=5.08e-14 · Best GWAS P=9.78e-22 conditioned to 1.26e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TGS1 | 0.05 | 0.01 | bslmm | 421 | 0.01 | 5.7e-02 | 5.3 | 5.9 | 3.2e-09 | 0.16 | 0.06 | 0.13 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TMEM68 | 0.10 | 0.09 | lasso | 3 | 0.09 | 2.4e-10 | 6.5 | 7.1 | 1.1e-12 | 0.67 | 0.13 | 0.87 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TMEM68 | 0.08 | 0.03 | blup | 40 | 0.02 | 7.2e-04 | 7.5 | 5.2 | 1.7e-07 | 0.52 | 0.00 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | TMEM68 | 0.12 | 0.05 | lasso | 3 | 0.05 | 2.3e-06 | 7.5 | 7.2 | 7.4e-13 | 0.57 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | TMEM68 | 0.08 | 0.02 | enet | 9 | 0.03 | 1.2e-04 | 7.5 | 6.6 | 3.1e-11 | 0.46 | 0.00 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | TMEM68 | 0.09 | 0.06 | lasso | 3 | 0.06 | 5.7e-05 | 7.5 | 7.0 | 2.0e-12 | 0.47 | 0.00 | 1.00 | FALSE |
| 7 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | TMEM68 | 0.18 | 0.10 | lasso | 1 | 0.08 | 3.0e-04 | 7.5 | 7.5 | 5.1e-14 | 0.57 | 0.00 | 0.99 | TRUE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | TMEM68 | 0.24 | 0.16 | enet | 9 | 0.20 | 1.3e-19 | 7.5 | 6.2 | 4.5e-10 | 0.40 | 0.00 | 1.00 | FALSE |