[Hub]/) : Traits : Blood White Count :

chr8:60,413,073-62,477,554

Best TWAS P=6.76e-41 · Best GWAS P=3.03e-53 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RAB2A 0.05 0.02 bslmm 454 0.02 1.7e-03 8.9 7.2 6.3e-13 -0.02 0.88 0.00 FALSE
2 GTEx Artery Aorta RAB2A 0.13 0.19 lasso 3 0.19 1.7e-10 9.0 9.0 2.7e-19 0.19 1.00 0.00 FALSE
3 GTEx Artery Tibial RAB2A 0.10 0.14 lasso 6 0.12 2.9e-09 8.9 8.8 9.4e-19 0.20 1.00 0.00 FALSE
4 GTEx Cells EBV-transformed lymphocytes RAB2A 0.26 0.15 enet 22 0.14 2.7e-05 8.9 8.8 1.3e-18 0.17 0.92 0.00 FALSE
5 GTEx Cells Transformed fibroblasts RAB2A 0.35 0.21 lasso 9 0.24 2.5e-18 8.9 9.2 2.8e-20 0.17 1.00 0.00 FALSE
6 GTEx Cells Transformed fibroblasts CHD7 0.07 0.00 lasso 8 0.01 3.7e-02 6.6 -7.2 4.6e-13 -0.39 0.06 0.43 TRUE
7 GTEx Colon Transverse RAB2A 0.14 0.05 enet 11 0.08 1.7e-04 4.6 6.5 7.0e-11 0.14 0.52 0.02 FALSE
8 GTEx Esophagus Muscularis RAB2A 0.21 0.16 lasso 5 0.12 1.2e-07 9.2 8.9 4.9e-19 0.20 1.00 0.00 FALSE
9 GTEx Heart Left Ventricle RAB2A 0.25 0.14 lasso 7 0.10 3.1e-06 6.8 5.3 1.0e-07 0.17 0.83 0.01 FALSE
10 GTEx Lung RAB2A 0.06 0.03 lasso 6 0.02 9.1e-03 8.9 9.2 2.2e-20 0.16 0.51 0.03 FALSE
11 GTEx Muscle Skeletal RAB2A 0.11 0.06 enet 29 0.07 1.4e-07 4.3 9.2 5.6e-20 0.35 0.98 0.00 TRUE
12 GTEx Nerve Tibial RAB2A 0.10 0.02 lasso 6 0.02 1.4e-02 8.8 9.1 1.2e-19 0.20 0.52 0.10 FALSE
13 GTEx Skin Sun Exposed Lower leg RAB2A 0.08 0.09 lasso 2 0.06 1.0e-05 9.0 9.0 2.5e-19 0.19 0.99 0.00 FALSE
14 GTEx Small Intestine Terminal Ileum RAB2A 0.32 0.10 lasso 10 0.04 4.5e-02 9.2 -8.3 8.2e-17 -0.22 0.14 0.05 FALSE
15 GTEx Spleen RAB2A 0.32 0.19 lasso 4 0.16 7.9e-05 9.2 9.2 3.7e-20 0.20 0.46 0.03 FALSE
16 GTEx Thyroid RAB2A 0.06 0.04 enet 8 0.04 9.5e-04 9.2 9.2 4.9e-20 0.16 0.67 0.04 FALSE
17 GTEx Whole Blood CHD7 0.07 0.02 enet 18 0.01 6.4e-02 -8.6 -6.6 4.1e-11 -0.49 0.02 0.88 FALSE
18 METSIM Adipose CA8 0.12 0.06 blup 386 0.06 1.0e-08 3.2 -7.7 1.3e-14 -0.15 1.00 0.00 FALSE
19 METSIM Adipose RAB2A 0.09 0.10 lasso 8 0.09 9.3e-14 8.8 9.1 1.1e-19 0.19 1.00 0.00 FALSE
20 NTR Blood CHD7 0.02 0.02 lasso 4 0.02 8.7e-07 15.4 -13.4 6.8e-41 -0.90 0.00 1.00 TRUE
21 YFS Blood CA8 0.05 0.04 enet 18 0.05 1.3e-14 8.8 -8.1 4.3e-16 -0.25 1.00 0.00 TRUE
22 YFS Blood CHD7 0.05 0.05 bslmm 486 0.05 8.9e-17 15.4 -12.2 2.7e-34 -0.95 0.00 1.00 FALSE
23 YFS Blood RAB2A 0.08 0.08 bslmm 447 0.11 4.5e-34 8.8 7.5 8.1e-14 0.19 1.00 0.00 FALSE
24 The Cancer Genome Atlas Bladder Urothelial Carcinoma RAB2A 0.08 0.05 lasso 2 0.06 7.3e-06 8.9 7.9 3.8e-15 0.15 0.02 0.97 TRUE
25 The Cancer Genome Atlas Breast Invasive Carcinoma RAB2A 0.01 0.02 lasso 3 0.01 7.5e-04 8.8 8.5 2.3e-17 0.15 0.02 0.96 FALSE
26 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma RAB2A 0.07 0.08 lasso 2 0.06 9.0e-04 -7.4 7.7 1.5e-14 0.22 0.03 0.50 FALSE
27 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RAB2A 0.03 0.02 blup 53 0.03 3.0e-04 9.2 8.8 1.5e-18 0.19 0.02 0.97 TRUE
28 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RAB2A 0.05 0.09 lasso 7 0.08 2.0e-09 6.6 7.6 3.2e-14 0.16 0.14 0.86 FALSE
29 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RAB2A 0.10 0.06 blup 51 0.07 3.4e-04 8.9 9.6 7.2e-22 0.22 0.02 0.95 TRUE
30 The Cancer Genome Atlas Lung Adenocarcinoma RAB2A 0.03 0.03 enet 4 0.03 6.1e-05 -6.7 7.3 1.9e-13 0.17 0.05 0.92 TRUE
31 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RAB2A 0.07 0.06 blup 51 0.06 2.5e-07 9.2 9.3 1.8e-20 0.24 0.02 0.98 FALSE
32 The Cancer Genome Atlas Stomach Adenocarcinoma RAB2A 0.04 0.04 blup 51 0.04 5.3e-04 9.2 8.8 1.5e-18 0.20 0.02 0.96 FALSE
33 The Cancer Genome Atlas Thyroid Carcinoma CA8 0.05 0.04 lasso 3 0.03 3.8e-04 -5.5 -5.5 4.4e-08 -0.09 0.09 0.86 FALSE
34 The Cancer Genome Atlas Thyroid Carcinoma RAB2A 0.06 0.03 blup 53 0.05 6.1e-06 5.0 8.6 8.3e-18 0.22 0.02 0.98 FALSE