[Hub]/) : Traits : Blood White Count : ← →

chr8:60,413,073-62,477,554

Best TWAS P=6.76e-41 · Best GWAS P=3.03e-53 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	NTR	Blood	CHD7	0.02	0.02	lasso	4	0.02	8.7e-07	15.4	-13.4	6.8e-41	-0.90	0.00	1.00	TRUE
29	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	RAB2A	0.10	0.06	blup	51	0.07	3.4e-04	8.9	9.6	7.2e-22	0.22	0.02	0.95	TRUE
11	GTEx	Muscle Skeletal	RAB2A	0.11	0.06	enet	29	0.07	1.4e-07	4.3	9.2	5.6e-20	0.35	0.98	0.00	TRUE
27	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RAB2A	0.03	0.02	blup	53	0.03	3.0e-04	9.2	8.8	1.5e-18	0.19	0.02	0.97	TRUE
21	YFS	Blood	CA8	0.05	0.04	enet	18	0.05	1.3e-14	8.8	-8.1	4.3e-16	-0.25	1.00	0.00	TRUE
24	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RAB2A	0.08	0.05	lasso	2	0.06	7.3e-06	8.9	7.9	3.8e-15	0.15	0.02	0.97	TRUE
30	The Cancer Genome Atlas	Lung Adenocarcinoma	RAB2A	0.03	0.03	enet	4	0.03	6.1e-05	-6.7	7.3	1.9e-13	0.17	0.05	0.92	TRUE
6	GTEx	Cells Transformed fibroblasts	CHD7	0.07	0.00	lasso	8	0.01	3.7e-02	6.6	-7.2	4.6e-13	-0.39	0.06	0.43	TRUE
22	YFS	Blood	CHD7	0.05	0.05	bslmm	486	0.05	8.9e-17	15.4	-12.2	2.7e-34	-0.95	0.00	1.00	FALSE
31	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RAB2A	0.07	0.06	blup	51	0.06	2.5e-07	9.2	9.3	1.8e-20	0.24	0.02	0.98	FALSE
10	GTEx	Lung	RAB2A	0.06	0.03	lasso	6	0.02	9.1e-03	8.9	9.2	2.2e-20	0.16	0.51	0.03	FALSE
5	GTEx	Cells Transformed fibroblasts	RAB2A	0.35	0.21	lasso	9	0.24	2.5e-18	8.9	9.2	2.8e-20	0.17	1.00	0.00	FALSE
15	GTEx	Spleen	RAB2A	0.32	0.19	lasso	4	0.16	7.9e-05	9.2	9.2	3.7e-20	0.20	0.46	0.03	FALSE
16	GTEx	Thyroid	RAB2A	0.06	0.04	enet	8	0.04	9.5e-04	9.2	9.2	4.9e-20	0.16	0.67	0.04	FALSE
19	METSIM	Adipose	RAB2A	0.09	0.10	lasso	8	0.09	9.3e-14	8.8	9.1	1.1e-19	0.19	1.00	0.00	FALSE
12	GTEx	Nerve Tibial	RAB2A	0.10	0.02	lasso	6	0.02	1.4e-02	8.8	9.1	1.2e-19	0.20	0.52	0.10	FALSE
13	GTEx	Skin Sun Exposed Lower leg	RAB2A	0.08	0.09	lasso	2	0.06	1.0e-05	9.0	9.0	2.5e-19	0.19	0.99	0.00	FALSE
2	GTEx	Artery Aorta	RAB2A	0.13	0.19	lasso	3	0.19	1.7e-10	9.0	9.0	2.7e-19	0.19	1.00	0.00	FALSE
8	GTEx	Esophagus Muscularis	RAB2A	0.21	0.16	lasso	5	0.12	1.2e-07	9.2	8.9	4.9e-19	0.20	1.00	0.00	FALSE
3	GTEx	Artery Tibial	RAB2A	0.10	0.14	lasso	6	0.12	2.9e-09	8.9	8.8	9.4e-19	0.20	1.00	0.00	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	RAB2A	0.26	0.15	enet	22	0.14	2.7e-05	8.9	8.8	1.3e-18	0.17	0.92	0.00	FALSE
32	The Cancer Genome Atlas	Stomach Adenocarcinoma	RAB2A	0.04	0.04	blup	51	0.04	5.3e-04	9.2	8.8	1.5e-18	0.20	0.02	0.96	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	RAB2A	0.06	0.03	blup	53	0.05	6.1e-06	5.0	8.6	8.3e-18	0.22	0.02	0.98	FALSE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	RAB2A	0.01	0.02	lasso	3	0.01	7.5e-04	8.8	8.5	2.3e-17	0.15	0.02	0.96	FALSE
14	GTEx	Small Intestine Terminal Ileum	RAB2A	0.32	0.10	lasso	10	0.04	4.5e-02	9.2	-8.3	8.2e-17	-0.22	0.14	0.05	FALSE
18	METSIM	Adipose	CA8	0.12	0.06	blup	386	0.06	1.0e-08	3.2	-7.7	1.3e-14	-0.15	1.00	0.00	FALSE
26	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RAB2A	0.07	0.08	lasso	2	0.06	9.0e-04	-7.4	7.7	1.5e-14	0.22	0.03	0.50	FALSE
28	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RAB2A	0.05	0.09	lasso	7	0.08	2.0e-09	6.6	7.6	3.2e-14	0.16	0.14	0.86	FALSE
23	YFS	Blood	RAB2A	0.08	0.08	bslmm	447	0.11	4.5e-34	8.8	7.5	8.1e-14	0.19	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	RAB2A	0.05	0.02	bslmm	454	0.02	1.7e-03	8.9	7.2	6.3e-13	-0.02	0.88	0.00	FALSE
17	GTEx	Whole Blood	CHD7	0.07	0.02	enet	18	0.01	6.4e-02	-8.6	-6.6	4.1e-11	-0.49	0.02	0.88	FALSE
7	GTEx	Colon Transverse	RAB2A	0.14	0.05	enet	11	0.08	1.7e-04	4.6	6.5	7.0e-11	0.14	0.52	0.02	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	CA8	0.05	0.04	lasso	3	0.03	3.8e-04	-5.5	-5.5	4.4e-08	-0.09	0.09	0.86	FALSE
9	GTEx	Heart Left Ventricle	RAB2A	0.25	0.14	lasso	7	0.10	3.1e-06	6.8	5.3	1.0e-07	0.17	0.83	0.01	FALSE