TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Blood White Count
:
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chr10:24,445,550-25,939,515
Best TWAS P=3.12e-93 · Best GWAS P=4.05e-99 conditioned to 1.32e-09
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells Transformed fibroblasts
PRTFDC1
0.24
0.03
lasso
4
0.02
1.1e-02
-21.0
20.5
3.1e-93
-0.9
0.01
0.98
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
PRTFDC1
0.15
0.06
bslmm
460
0.06
1.0e-08
-1.4
-7.6
3.0e-14
0.4
0.85
0.14
FALSE