Best TWAS P=3.12e-93 · Best GWAS P=4.05e-99 conditioned to 1.32e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PRTFDC1 | 0.24 | 0.03 | lasso | 4 | 0.02 | 1.1e-02 | -21.0 | 20.5 | 3.1e-93 | -0.9 | 0.01 | 0.98 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | PRTFDC1 | 0.15 | 0.06 | bslmm | 460 | 0.06 | 1.0e-08 | -1.4 | -7.6 | 3.0e-14 | 0.4 | 0.85 | 0.14 | FALSE |