[Hub]/) : Traits : Blood White Count :

chr10:26,033,058-27,769,933

Best TWAS P=8.7e-12 · Best GWAS P=8.19e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial APBB1IP 0.19 0.16 enet 5 0.17 2.6e-13 6.5 6.5 6.8e-11 1.00 0.01 0.99 FALSE
2 GTEx Cells Transformed fibroblasts APBB1IP 0.30 0.20 lasso 10 0.20 4.9e-15 6.5 6.8 8.7e-12 0.97 0.01 0.99 TRUE
3 GTEx Esophagus Muscularis APBB1IP 0.12 0.09 lasso 3 0.08 1.6e-05 6.5 6.5 7.3e-11 0.99 0.01 0.99 FALSE
4 GTEx Pituitary APBB1IP 0.53 0.37 lasso 8 0.38 1.6e-10 6.5 6.0 1.9e-09 0.99 0.01 0.99 FALSE
5 GTEx Stomach APBB1IP 0.31 0.05 lasso 4 0.05 2.9e-03 6.1 5.8 8.2e-09 0.86 0.02 0.95 FALSE
6 METSIM Adipose APBB1IP 0.07 0.04 lasso 6 0.03 8.2e-06 6.5 6.2 5.2e-10 0.97 0.01 0.99 FALSE
7 YFS Blood APBB1IP 0.08 0.06 lasso 3 0.06 1.3e-18 -6.1 -6.2 7.8e-10 -0.59 0.07 0.93 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma APBB1IP 0.04 0.03 blup 103 0.03 4.6e-06 6.5 6.3 2.2e-10 0.82 0.01 0.99 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ACBD5 0.04 0.02 blup 59 0.03 3.9e-04 3.8 5.7 1.0e-08 0.08 0.00 0.27 TRUE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma APBB1IP 0.06 0.07 lasso 2 0.06 1.0e-07 6.1 6.1 1.0e-09 0.92 0.02 0.98 FALSE