Best TWAS P=2.1e-09 · Best GWAS P=1.06e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | DLG5 | 0.22 | 0.14 | lasso | 6 | 0.11 | 8.5e-05 | 4.8 | 5.6 | 2.7e-08 | 0.95 | 0.02 | 0.96 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | DLG5 | 0.32 | 0.23 | lasso | 4 | 0.24 | 3.9e-11 | 5.1 | 5.1 | 3.1e-07 | 0.99 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Liver | DLG5 | 0.42 | 0.31 | lasso | 5 | 0.28 | 2.1e-08 | 5.3 | 5.2 | 2.5e-07 | 0.99 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Ovary | DLG5 | 0.62 | 0.38 | lasso | 6 | 0.40 | 5.3e-11 | 5.3 | 5.7 | 1.3e-08 | 0.98 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Ovary | RP13-39P12.3 | 0.42 | 0.29 | lasso | 5 | 0.33 | 7.5e-09 | 5.3 | 6.0 | 2.1e-09 | 0.96 | 0.01 | 0.99 | TRUE |