[Hub]/) : Traits : Blood White Count : ← →

chr10:68,861,272-70,532,990

Best TWAS P=4.83e-12 · Best GWAS P=6.26e-12 conditioned to 0.023

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Muscle Skeletal	DNAJC12	0.05	0.04	enet	9	0.02	2.7e-03	-6.1	-6.9	4.8e-12	0.80	0.13	0.83	TRUE
10	The Cancer Genome Atlas	Prostate Adenocarcinoma	SIRT1	0.05	0.06	enet	8	0.06	1.7e-06	-6.5	-6.7	2.5e-11	0.59	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Thyroid Carcinoma	SIRT1	0.04	0.05	lasso	1	0.04	2.0e-04	-6.6	-6.6	3.1e-11	0.51	0.01	0.99	FALSE
6	YFS	Blood	SIRT1	0.10	0.20	lasso	5	0.20	1.4e-63	-6.7	-6.6	3.9e-11	0.51	0.02	0.98	FALSE
11	The Cancer Genome Atlas	Thyroid Carcinoma	HERC4	0.04	0.02	lasso	4	0.03	3.1e-04	-5.9	-6.5	8.3e-11	0.57	0.03	0.94	FALSE
4	GTEx	Whole Blood	SIRT1	0.07	0.07	enet	7	0.06	1.3e-06	-6.5	-6.5	1.0e-10	0.50	0.05	0.95	FALSE
7	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SIRT1	0.02	0.02	blup	42	0.01	6.3e-02	-6.6	-6.2	5.4e-10	0.44	0.01	0.87	FALSE
9	The Cancer Genome Atlas	Lung Adenocarcinoma	HERC4	0.03	0.02	blup	77	0.01	6.7e-03	-6.0	-5.7	9.9e-09	0.42	0.05	0.87	FALSE
5	YFS	Blood	HERC4	0.03	0.02	bslmm	402	0.03	6.2e-10	-5.2	-5.6	1.7e-08	0.72	0.24	0.76	FALSE
2	GTEx	Testis	DNAJC12	0.22	0.15	lasso	6	0.12	5.2e-06	-4.4	-5.5	4.9e-08	0.64	0.12	0.81	FALSE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SIRT1	0.03	0.02	blup	42	0.03	3.2e-04	-6.6	-5.4	5.4e-08	0.37	0.02	0.94	FALSE
3	GTEx	Testis	HERC4	0.12	0.08	lasso	2	0.05	2.0e-03	-5.2	-5.2	1.6e-07	0.77	0.05	0.78	FALSE