Best TWAS P=9.5e-08 · Best GWAS P=1.99e-08 conditioned to 0.553
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | SMUG1 | 0.30 | 0.17 | enet | 20 | 0.24 | 3.6e-11 | 4.1 | 5.3 | 1.2e-07 | -0.21 | 0.48 | 0.45 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | HOXC5 | 0.02 | 0.00 | blup | 51 | 0.01 | 2.4e-02 | -3.9 | -5.2 | 2.1e-07 | 0.59 | 0.02 | 0.06 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HOXC6 | 0.03 | 0.02 | blup | 50 | 0.03 | 3.9e-04 | -4.4 | 5.3 | 9.5e-08 | -0.78 | 0.04 | 0.78 | TRUE |