Best TWAS P=1.36e-14 · Best GWAS P=4.96e-16 conditioned to 2.33e-12
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | SLC39A9 | 0.08 | 0.05 | bslmm | 476 | 0.05 | 3.0e-15 | 7.6 | 7.7 | 1.4e-14 | 0.02 | 0.00 | 1.00 | TRUE |
2 | YFS | Blood | ZFP36L1 | 0.05 | 0.02 | lasso | 5 | 0.02 | 3.5e-07 | -7.9 | 7.1 | 1.1e-12 | 0.15 | 0.01 | 0.99 | TRUE |
3 | The Cancer Genome Atlas | Rectum Adenocarcinoma | ZFP36L1 | 0.63 | 0.02 | blup | 59 | 0.09 | 4.3e-03 | 8.1 | -6.3 | 3.8e-10 | -0.48 | 0.00 | 0.50 | FALSE |