Best TWAS P=8.89e-10 · Best GWAS P=9.62e-10 conditioned to 1.91e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | IFT52 | 0.12 | 0.06 | lasso | 3 | 0.10 | 2.6e-12 | -4.7 | 5.9 | 3.3e-09 | -0.10 | 0.04 | 0.96 | FALSE |
| 2 | GTEx | Artery Aorta | IFT52 | 0.26 | 0.16 | lasso | 7 | 0.14 | 3.1e-08 | -4.7 | 5.4 | 5.8e-08 | -0.09 | 0.28 | 0.72 | FALSE |
| 3 | GTEx | Artery Tibial | IFT52 | 0.15 | 0.06 | enet | 7 | 0.07 | 1.8e-06 | -5.4 | 5.8 | 5.1e-09 | -0.07 | 0.02 | 0.97 | FALSE |
| 4 | GTEx | Brain Cerebellar Hemisphere | IFT52 | 0.32 | 0.15 | lasso | 3 | 0.13 | 4.0e-04 | -5.4 | 5.4 | 8.7e-08 | -0.08 | 0.05 | 0.86 | FALSE |
| 5 | GTEx | Brain Cerebellum | IFT52 | 0.18 | 0.16 | lasso | 3 | 0.10 | 6.1e-04 | -5.4 | 5.4 | 7.3e-08 | -0.06 | 0.06 | 0.73 | FALSE |
| 6 | GTEx | Esophagus Mucosa | IFT52 | 0.11 | 0.14 | lasso | 3 | 0.12 | 3.7e-08 | -4.7 | 5.4 | 6.3e-08 | -0.09 | 0.14 | 0.85 | FALSE |
| 7 | GTEx | Esophagus Muscularis | IFT52 | 0.19 | 0.09 | enet | 12 | 0.14 | 5.1e-09 | -5.4 | 5.7 | 1.3e-08 | -0.07 | 0.02 | 0.98 | FALSE |
| 8 | METSIM | Adipose | MYBL2 | 0.11 | 0.08 | lasso | 3 | 0.07 | 1.1e-10 | -5.8 | -6.1 | 8.9e-10 | 0.08 | 0.00 | 1.00 | TRUE |
| 9 | The Cancer Genome Atlas | Brain Lower Grade Glioma | IFT52 | 0.15 | 0.05 | enet | 11 | 0.10 | 1.4e-11 | -5.0 | 5.2 | 2.1e-07 | -0.11 | 0.03 | 0.97 | FALSE |
| 10 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | IFT52 | 0.11 | 0.04 | lasso | 9 | 0.07 | 1.6e-05 | -4.9 | 5.8 | 6.0e-09 | -0.10 | 0.02 | 0.95 | FALSE |