Best TWAS P=2.92e-09 · Best GWAS P=4.55e-09 conditioned to 0.00542
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Small Intestine Terminal Ileum | CLHC1 | 0.51 | 0.29 | lasso | 4 | 0.30 | 2.3e-07 | 4.1 | 5.2 | 1.7e-07 | 0.10 | 0.31 | 0.17 | FALSE |
2 | GTEx | Stomach | CLHC1 | 0.59 | 0.36 | enet | 42 | 0.44 | 9.3e-23 | 4.1 | 5.4 | 6.6e-08 | 0.17 | 0.93 | 0.06 | FALSE |
3 | GTEx | Whole Blood | SPTBN1 | 0.13 | 0.04 | lasso | 6 | 0.08 | 5.7e-08 | 5.6 | 5.9 | 3.3e-09 | 0.88 | 0.01 | 0.99 | FALSE |
4 | NTR | Blood | SPTBN1 | 0.06 | 0.04 | bslmm | 640 | 0.04 | 3.2e-14 | 2.1 | 5.9 | 2.9e-09 | 0.62 | 0.99 | 0.00 | TRUE |