TWAS hub - SPTBN1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1010	0.0370	1.3e-03	0.018	NA	0.042	NA	0.035	1.2e-02	NA	2.4e-04	NA	7.1e-04
2	GTEx	Artery Aorta	0.1700	0.0540	3.4e-05	0.091	NA	0.103	NA	0.091	1.1e-05	NA	2.7e-06	NA	1.1e-05
3	GTEx	Artery Tibial	0.2094	0.0652	5.4e-07	0.138	NA	0.106	NA	0.148	6.2e-11	NA	1.1e-08	NA	1.1e-11
4	GTEx	Brain Frontal Cortex BA9	0.2537	0.0948	1.0e-02	-0.003	NA	0.070	NA	0.005	4.1e-01	NA	6.5e-03	NA	2.3e-01
5	GTEx	Breast Mammary Tissue	0.1960	0.0690	7.9e-04	0.000	NA	0.071	NA	0.020	3.2e-01	NA	1.7e-04	NA	3.1e-02
6	GTEx	Breast Mammary Tissue (Male)	0.1868	0.0979	4.8e-02	-0.013	NA	-0.005	NA	-0.006	9.0e-01	NA	4.3e-01	NA	4.6e-01
7	GTEx	Breast Mammary Tissue (Female)	0.1531	0.0883	4.6e-02	-0.007	NA	-0.010	NA	-0.005	6.1e-01	NA	1.0e+00	NA	4.7e-01
8	GTEx	Esophagus Mucosa	0.1710	0.0530	1.1e-04	-0.002	NA	0.024	NA	0.016	5.0e-01	NA	9.0e-03	NA	2.7e-02
9	GTEx	Esophagus Muscularis	0.2190	0.0560	6.0e-07	0.064	NA	0.110	NA	0.037	1.0e-04	NA	3.5e-07	NA	2.7e-03
10	GTEx	Lung	0.0953	0.0343	1.2e-03	0.018	NA	0.049	NA	0.046	1.4e-02	NA	1.3e-04	NA	1.9e-04
11	GTEx	Muscle Skeletal	0.1046	0.0348	7.9e-05	0.085	NA	0.095	NA	0.091	1.0e-08	NA	1.3e-09	NA	3.3e-09
12	GTEx	Nerve Tibial	0.1560	0.0409	1.3e-06	0.005	NA	0.066	NA	0.061	1.3e-01	NA	2.0e-05	NA	3.7e-05
13	GTEx	Thyroid	0.1390	0.0410	6.7e-05	0.014	NA	0.032	NA	0.033	2.8e-02	NA	1.7e-03	NA	1.3e-03
14	GTEx	Whole Blood	0.1290	0.0370	6.0e-06	0.035	NA	0.077	NA	0.082	3.2e-04	NA	1.5e-07	NA	5.7e-08
15	NTR	Blood	0.0631	0.0157	2.4e-12	0.036	0.043	0.042	0.045	0.043	9.4e-12	9.8e-14	1.9e-13	3.2e-14	1.0e-13
16	ROSMAP	Brain Pre-frontal Cortex	0.1010	0.0287	9.1e-06	0.025	0.057	0.064	0.063	0.058	2.8e-04	6.7e-08	1.1e-08	1.6e-08	5.3e-08
17	TCGA	Head and Neck Squamous Cell Carcinoma	0.0512	0.0237	2.3e-03	0.031	0.029	0.027	NA	0.023	1.7e-04	2.9e-04	4.9e-04	NA	1.1e-03
18	TCGA	Brain Lower Grade Glioma	0.0979	0.0403	1.6e-05	0.039	0.041	0.044	NA	0.050	2.6e-05	1.9e-05	9.7e-06	NA	2.1e-06
19	TCGA	Pheochromocytoma and Paraganglioma	0.1490	0.0740	4.3e-03	0.067	0.046	0.034	NA	0.049	1.2e-03	6.6e-03	1.7e-02	NA	5.2e-03
20	TCGA	Prostate Adenocarcinoma	0.0631	0.0260	9.2e-06	0.043	0.053	0.047	NA	0.039	2.7e-05	3.1e-06	1.1e-05	NA	5.2e-05
21	TCGA	Thyroid Carcinoma	0.0540	0.0300	3.2e-03	-0.002	0.009	0.020	NA	-0.003	5.5e-01	3.9e-02	4.1e-03	NA	7.7e-01
22	TCGA	Uterine Corpus Endometrial Carcinoma	0.3900	0.1270	3.6e-04	0.039	0.118	0.089	NA	0.085	2.9e-02	3.6e-04	1.8e-03	NA	2.3e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Heel T-Score	23.7	188.4	1190.2	5.0	9.5	13.0	12.5	3.3	3.5	-1.5	2.4	-4.4	-0.6	5.9	-0.8	-6.7	-23.4	-32.6	-12.9	-7.2	-17.8	-9.7	11.1	-4.5	-34.5
Heel bone mineral density (BMD) T-score, automated (right)	13.3	30.6	204.5	2.4	4.5	6.0	4.8	2.0	1.1	-1.1	1.1	-1.6	-0.0	2.5	0.1	-2.2	-8.5	-12.8	-5.1	-3.5	-7.3	-3.4	4.7	-0.2	-14.3
Heel bone mineral density (BMD) T-score, automated (left)	12.3	27.9	169.0	1.8	3.9	4.8	5.0	1.4	1.1	-0.2	0.9	-2.0	-0.8	2.1	-0.1	-2.2	-8.5	-12.6	-5.4	-3.0	-7.4	-4.1	4.3	-0.9	-13.0
Hearing aid user	10.1	11.4	30.6	5.5	5.3	5.1	2.5	3.9	-0.7	1.3	2.8	4.4	4.5	1.2	3.7	3.6	0.8	0.1	2.5	-0.2	2.3	3.4	4.2	4.7	-2.2
Hearing difficulty/problems: Yes	5.4	8.2	22.0	4.3	3.9	3.4	0.3	2.5	-1.0	1.1	3.0	4.2	4.7	1.4	2.8	3.8	0.8	-0.3	2.3	-0.7	3.5	3.1	3.6	3.4	0.2
Tinnitus: Yes, now most or all of the time	3.8	4.4	10.8	2.2	3.0	2.3	0.0	2.4	-0.5	-0.7	2.5	3.1	2.3	2.6	1.8	2.6	0.2	-0.4	1.0	-0.6	3.1	1.9	2.8	3.3	0.6
Number of incorrect matches in round	3.6	5.9	16.2	2.4	2.4	1.2	4.0	3.8	-2.5	2.0	3.8	2.0	1.9	0.9	3.2	2.1	0.6	0.7	2.7	2.3	1.3	3.0	2.6	2.1	1.8
Hair/balding pattern: Pattern 2	3.6	4.6	10.9	-2.8	-3.3	-3.3	-0.8	-2.0	0.5	-0.0	-1.2	-2.2	-3.2	-1.8	-1.8	-2.6	1.5	0.7	-2.7	1.1	-2.4	-2.5	-2.5	-1.5	2.6
High blood pressure (siblings)	3.6	5.3	16.8	-2.2	-3.2	-2.6	-1.3	-2.8	1.2	-0.2	-0.6	-3.5	-4.1	-2.6	-2.0	-2.3	-1.4	-0.7	-2.6	1.6	-3.5	-1.3	-2.4	-2.4	0.6
Number of live births	3.5	5.0	11.4	-3.0	-2.5	-2.2	-3.4	-2.9	0.6	-1.4	-2.7	-2.9	-2.9	-2.5	-2.6	-2.9	-0.3	-0.8	-1.9	0.3	-1.2	-1.6	-1.9	-3.0	1.1
Commuting to job workplace: Cycle	3.4	4.1	10.0	-3.2	-2.9	-2.2	-2.6	-2.3	-0.9	-2.2	-1.6	-2.4	-1.9	-2.1	-2.4	-2.7	0.1	-1.0	-2.0	-0.2	-1.4	-1.9	-1.3	-2.6	0.5
Supplements: Fish oil (including cod liver oil)	2.8	3.7	13.2	-0.6	0.4	0.5	-0.2	-2.4	0.7	-2.7	-3.6	-1.4	-0.8	-0.4	-1.8	-2.9	-2.5	-3.0	-2.1	-0.9	-1.1	-1.7	0.3	-2.4	-2.8
Fractured/broken bones in last 5 years	2.5	3.2	8.7	0.8	1.5	1.0	-1.1	-0.9	-1.8	-1.9	1.3	2.1	2.1	1.2	3.0	0.4	2.6	2.4	1.5	0.9	2.6	2.6	1.3	1.9	1.6
Ever had hysterectomy (womb removed)	2.4	2.8	8.9	-2.1	-1.8	-2.1	-2.2	-0.6	-0.5	0.2	-0.7	-1.9	-1.9	-3.0	-2.0	-1.1	2.4	2.8	-0.4	0.2	-0.4	0.1	-1.9	-1.4	1.4
Birth weight of first child	2.4	4.3	12.9	-2.7	-2.7	-3.0	-1.2	-0.6	2.5	1.9	-0.8	-1.6	-3.0	0.5	-1.8	-1.6	-0.9	-0.4	-3.2	-1.4	-1.8	-3.6	-2.8	-2.2	0.3
Had major operations	2.3	2.6	10.4	3.2	1.8	2.1	0.9	1.9	-0.6	-0.7	1.7	2.5	1.9	0.7	0.9	2.6	-0.2	-0.8	0.9	0.5	1.6	1.6	1.8	2.0	0.8
Average weekly champagne plus white wine intake	2.2	3.1	9.0	1.6	1.8	1.7	-0.4	2.8	-1.5	1.2	2.6	3.0	1.8	2.5	1.4	1.4	-0.6	-1.2	1.6	0.6	2.0	0.6	2.5	1.4	0.8
Sensitivity / hurt feelings	2.1	3.7	11.0	1.9	2.4	1.9	2.0	2.2	-0.6	-0.2	2.0	2.2	2.6	1.0	1.9	1.6	1.1	1.5	2.9	0.8	3.3	2.2	2.0	1.6	-0.4
Ever taken oral contraceptive pill	2.1	2.4	6.4	1.5	2.1	1.5	1.7	-0.5	-1.4	-1.1	1.0	2.1	1.1	2.0	2.1	2.1	0.6	1.0	0.3	0.3	1.4	1.2	1.8	2.5	1.7
Medication: Bendroflumethiazide	2.0	3.0	11.2	-2.1	-2.0	-2.4	-0.4	-1.4	0.2	-0.6	-1.2	-2.8	-3.3	-1.5	-1.7	-2.0	-0.4	-0.4	-0.5	2.5	-3.0	-0.7	-0.7	-1.5	1.5
Schizophrenia (2014)	1.9	4.1	11.4	-1.8	-1.8	-2.4	-2.3	-2.6	-0.0	-2.0	-3.2	-0.9	-1.5	0.3	-2.9	-0.2	1.2	2.5	-0.7	-3.4	1.9	-2.3	-2.0	-1.7	2.5
Tinnitus: Yes, but not now, but have in the past	1.9	2.0	7.1	-2.2	-1.0	-1.3	-0.1	-0.5	0.3	-0.2	-1.4	-1.7	-0.3	-1.9	-1.3	-1.1	0.9	2.0	-0.3	-1.8	-0.5	-0.8	-2.0	-2.7	-2.0
Serious illness, injury or assault to yourself	1.9	2.3	19.8	0.2	-1.4	-1.1	-1.7	-1.0	-0.9	1.9	0.5	-0.1	-1.1	-2.0	-0.5	0.6	1.4	1.9	0.7	1.6	0.4	1.7	-1.2	-0.7	4.4
Diabetes diagnosed by doctor	1.9	3.0	11.0	-2.1	-2.6	-2.7	-1.9	-0.9	0.3	-0.3	-1.3	-2.2	-1.9	-1.5	-2.6	-1.5	0.6	1.1	0.1	0.1	-0.5	-1.4	-2.2	-3.3	1.5
Mouth/teeth dental problems: Mouth ulcers	1.9	3.1	18.1	1.8	2.0	1.2	2.7	1.9	-1.6	1.6	1.6	1.9	1.1	4.3	1.6	0.8	-1.2	-2.8	0.2	-1.0	-0.0	-0.9	1.6	0.9	0.6
Osteoporosis (self-reported)	1.9	2.4	11.3	-1.7	-2.1	-2.2	-1.4	-1.0	-0.4	0.8	0.2	-1.4	-2.1	-1.8	-0.2	0.3	2.7	3.4	0.6	1.3	0.7	0.5	-1.8	-0.5	1.6
Alzheimer’s Disease (in father)	1.8	1.9	6.1	-2.4	-2.5	-1.9	-1.0	-0.1	-0.3	0.0	0.2	-1.7	-0.9	-1.7	-1.9	-1.1	0.9	0.9	-0.7	0.0	-1.1	-1.5	-2.1	-1.8	0.8
Major Depression (MDD)	1.8	2.2	5.1	-2.2	-1.7	-2.0	-1.6	-0.9	-0.2	0.6	-1.5	-1.8	-1.8	-0.7	-2.1	-1.5	-0.1	0.8	-1.3	-1.3	-1.4	-1.4	-2.3	-2.0	-0.8
Hearing difficulty/problems with background noise	1.8	2.9	8.8	3.0	2.9	2.5	0.9	1.3	-0.5	0.4	1.9	1.9	2.0	0.2	1.7	2.4	-0.3	-1.0	1.2	-0.8	1.7	1.5	2.2	1.7	-1.4
Illnesses of siblings	1.8	2.6	8.4	1.8	1.9	1.8	0.4	1.8	-0.5	0.2	0.9	2.4	2.9	2.3	1.2	2.5	0.5	-0.1	1.4	-1.1	1.7	1.4	1.7	1.8	-0.2
Worrier / anxious feelings	1.8	3.5	12.6	2.3	2.4	2.2	3.6	2.8	0.6	-0.5	1.3	1.6	1.8	1.7	1.4	1.1	-1.4	-1.6	2.6	2.0	0.5	0.8	3.0	0.5	-0.8
Medication: Lisinopril	1.8	2.4	11.0	1.0	-0.1	-0.6	-0.4	0.5	0.9	0.2	1.4	0.1	-0.2	-0.3	1.4	0.1	1.6	1.9	2.4	3.3	1.6	3.2	0.8	0.3	3.1
Townsend deprivation index at recruitment	1.7	2.4	12.1	-2.2	-1.5	-1.1	-1.2	-3.5	1.0	-2.6	-1.9	-1.4	-1.5	0.4	-1.0	-2.4	-1.3	-0.7	-1.0	1.0	-0.8	-0.9	-1.0	-1.1	0.0
Relative age voice broke	1.7	2.6	5.9	-1.5	-1.7	-1.9	-2.4	-2.1	0.9	-1.0	-1.5	-1.8	-1.7	0.4	-2.1	-2.1	-1.6	-1.3	-1.2	-0.4	-1.1	-2.2	-1.0	-1.9	1.4
Hair/balding pattern: Pattern 3	1.7	2.6	8.2	1.4	2.0	1.8	1.7	0.8	1.4	0.6	1.3	1.6	1.1	2.2	1.6	-0.7	-2.6	-2.9	1.1	0.6	1.5	-0.1	2.9	0.1	-1.4
Supplements: Vitamin C	1.7	2.1	6.8	1.6	2.3	1.8	2.6	0.4	-1.1	-1.6	-0.3	1.6	2.4	1.8	1.4	0.1	-1.2	-1.4	1.1	-0.5	1.0	0.4	1.5	0.8	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.2	17.1	3.3	3.4	3.2	-1.0	1.4	-0.8	0.1	1.2	3.0	2.1	2.5	2.7	4.1	0.9	0.5	1.6	-0.0	2.0	3.1	1.8	3.3	0.3
Rheumatoid Arthritis	1.5	2.0	6.9	1.9	1.0	1.4	0.4	0.9	-0.8	1.5	2.6	2.0	1.9	1.1	1.3	1.9	-0.4	0.1	1.2	1.2	1.4	1.1	1.9	1.8	0.4
Pulse rate	1.5	2.5	7.0	2.0	0.9	1.5	1.1	2.2	1.1	2.4	2.1	1.3	0.5	0.7	2.6	2.5	-0.4	-0.3	0.7	2.1	-1.0	1.5	1.0	2.0	0.8
Pulse wave reflection index	1.5	1.9	5.8	-1.7	-1.6	-0.7	-0.5	-0.9	0.3	-1.0	-2.4	-2.1	-1.8	-0.9	-1.7	-2.4	-0.3	0.5	-1.1	0.4	-1.4	-0.7	-1.1	-1.6	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	3.8	-1.5	-1.1	-1.1	-1.5	-0.7	-0.5	1.9	-0.8	-1.3	-1.8	-0.3	-1.5	-1.1	-1.7	-1.7	-1.9	-0.2	-1.3	-1.6	-0.3	-1.2	0.4
Medication: Blood pressure	1.5	2.9	18.2	-1.1	-1.5	-1.0	-0.2	-2.1	1.9	-2.1	0.2	-1.6	-2.0	-0.8	-0.4	-3.0	-0.5	-1.2	0.5	4.3	-2.3	0.2	0.5	-1.2	1.7
HbA1C	1.4	1.6	7.3	1.8	1.4	1.8	1.2	0.4	-0.8	-1.2	0.9	1.0	1.9	0.3	0.8	-0.7	0.5	0.9	1.9	0.1	0.9	2.7	0.4	1.5	0.6
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	4.5	-1.2	-1.2	-1.4	-0.4	-1.6	1.3	1.7	-0.4	-0.6	-1.2	-0.9	-1.6	-0.7	-1.2	-0.7	-1.6	-1.1	-0.6	-2.1	-1.3	-1.6	0.2
Mouth/teeth dental problems: Dentures	1.4	2.4	7.0	-1.9	-2.6	-2.1	-1.2	-1.1	1.8	-0.8	-1.4	-1.7	-1.7	-0.4	-2.0	-1.5	-0.3	0.1	-1.2	-0.3	-0.7	-1.6	-2.0	-1.4	2.3
Loud music exposure frequency	1.4	1.5	6.2	1.0	1.3	1.3	-1.3	-2.1	0.5	-1.9	-1.1	1.6	0.8	2.5	0.9	0.2	0.2	-0.9	-1.5	-0.5	-0.7	0.1	0.9	1.7	0.1
Illnesses of father: High blood pressure	1.4	1.7	8.1	-0.6	-0.6	-0.0	-0.5	-2.2	-1.2	-1.0	0.4	-0.4	-1.5	1.6	-0.4	-0.7	-1.4	-1.6	-2.2	1.1	-2.8	-1.3	0.2	1.4	0.3
Bipolar Disorder or Schizophrenia	1.3	3.1	11.6	-1.2	-1.1	-2.0	-1.6	-1.8	-1.3	-1.9	-3.4	-1.1	-1.6	0.8	-2.4	-0.1	0.9	1.9	-0.4	-2.5	1.5	-2.1	-1.4	-1.8	2.4
Schizophrenia (2018)	1.3	2.6	7.5	-1.3	-1.4	-1.9	-1.6	-1.7	0.6	-1.0	-2.7	-0.8	-1.0	-0.0	-2.1	-0.2	1.1	2.5	0.3	-2.3	2.3	-1.7	-1.4	-1.7	2.2
Body Mass Index (BMI) (2010)	1.3	1.7	7.7	1.2	1.1	1.4	0.7	-0.7	2.8	-2.3	-0.3	-0.7	0.6	0.4	0.8	-1.2	-1.7	-1.4	2.1	1.2	0.5	1.7	1.0	-0.3	-1.2
Coronary Artery Disease (CAD)	1.3	1.6	7.2	0.7	1.2	1.5	-0.8	0.3	-2.7	-0.2	2.0	1.5	1.9	0.3	2.0	0.6	0.4	-0.2	0.4	0.2	0.7	1.7	1.3	1.6	-0.6
Asthma	1.3	2.5	6.8	-2.1	-2.6	-2.2	-1.3	-1.7	1.2	-1.7	-1.6	-2.0	-1.3	-1.1	-1.6	-1.3	1.0	2.0	0.6	-0.2	0.9	-0.5	-1.5	-2.5	1.0
Blood clot in the leg (DVT)	1.3	1.7	5.5	1.4	1.5	2.0	-0.5	-1.0	0.2	-1.2	1.3	1.4	1.9	1.4	2.3	-0.9	-0.2	-0.1	1.9	0.5	1.8	1.6	1.5	-0.2	-0.3
Number of full brothers	1.3	1.7	8.2	-0.8	-0.6	-0.2	-1.5	-1.2	1.6	-2.6	-1.5	-0.9	-0.1	-1.0	-0.4	-1.7	2.1	2.9	0.9	-0.4	0.6	-0.0	-0.9	-0.7	-0.7
Number of full sisters	1.3	1.6	6.7	-1.7	-1.2	-1.2	0.6	-1.1	-0.9	-1.3	-2.1	-1.4	-0.5	0.3	-0.8	-2.6	-0.8	-0.2	0.1	-0.6	1.5	-1.2	-0.5	-2.3	0.1
Family relationship satisfaction	1.3	1.6	5.0	-2.2	-1.3	-1.4	-1.0	-1.5	-1.0	1.6	-0.2	-0.5	-1.4	-0.8	-1.4	-0.7	1.0	2.2	-1.5	-1.6	-0.4	-0.6	-1.6	-0.3	-0.6
Mineral and other dietary supplements	1.3	1.8	7.7	-0.3	-1.0	-1.1	-0.4	1.0	-0.1	1.9	1.7	0.5	0.4	0.1	1.1	1.9	2.2	2.8	1.4	0.4	0.6	1.0	-0.9	0.9	2.5
Chronotype (morning person)	1.2	2.7	7.6	1.0	1.2	1.1	0.1	2.6	-1.1	2.4	2.5	2.7	1.7	2.1	-0.2	2.4	0.9	0.7	-0.4	-2.8	0.6	-0.4	0.5	1.9	-1.0
Supplements: Zinc	1.2	1.3	3.8	1.4	1.4	1.7	0.5	0.2	-0.8	-0.4	1.1	1.9	1.1	1.9	1.6	0.8	-0.6	-0.5	0.9	0.5	1.2	1.0	1.4	1.0	0.6
Qualifications: CSEs or equivalent	1.2	1.5	4.1	1.0	1.3	1.4	1.8	2.0	0.8	0.8	1.6	1.5	1.2	2.0	0.3	0.8	-0.7	-1.0	0.8	-0.8	0.8	-0.9	1.9	1.2	-0.4
Multivitamins +/- minerals	1.2	1.6	4.2	-0.3	-0.1	0.2	-1.3	-1.3	-1.1	-2.0	-1.2	-0.3	0.1	1.2	-2.1	-0.7	-1.3	-2.0	-2.0	-1.7	-0.8	-1.8	-0.1	-0.6	-0.8
Medication: Atenolol	1.2	1.5	5.2	0.6	1.0	1.2	1.2	-0.6	0.2	-0.9	1.9	0.7	0.4	0.8	2.3	-1.1	-0.6	-1.2	1.4	1.9	0.3	1.8	1.9	1.2	0.3
Breastfed as a baby	1.2	1.5	4.8	-1.9	-1.4	-1.7	-1.5	-0.9	-0.2	0.1	-0.4	-0.8	-1.6	-1.3	-1.4	-0.3	-1.0	-0.0	-1.6	-0.8	-0.6	-0.9	-1.8	-1.1	2.2
Tense / ‘highly strung’	1.2	2.0	12.5	0.4	0.8	1.4	2.0	0.6	-0.6	-1.9	0.2	0.8	2.2	1.2	1.5	-0.9	-1.7	-1.5	1.2	-0.6	0.8	-0.4	1.2	-0.5	-3.5
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	4.8	1.9	0.8	1.2	-0.0	2.2	-1.3	1.3	1.4	1.3	0.9	-0.5	0.8	1.7	-0.5	-1.2	0.5	0.9	-0.5	1.3	1.3	0.9	0.5
Pulse wave peak to peak time	1.2	1.4	4.7	1.0	1.1	0.9	-1.2	0.4	-0.7	1.8	1.3	2.2	1.7	1.3	0.3	1.5	0.1	-0.8	-0.8	-2.0	1.4	0.2	0.5	1.3	0.7
Eye problems/disorders: None of the above	1.2	1.3	3.3	0.5	1.1	1.3	1.7	1.1	-0.5	-1.8	0.8	0.8	1.1	1.6	1.8	0.8	-1.1	-0.7	1.3	1.0	1.0	1.5	1.2	0.6	0.5
Heart disease (mother)	1.2	1.4	4.3	1.4	1.3	1.2	0.3	0.7	-0.9	-1.2	0.6	0.9	1.3	0.6	1.1	0.7	0.9	1.2	2.1	1.1	1.8	0.9	1.4	1.5	-1.3
Comparative height size at age 10	1.2	6.6	20.4	2.8	3.1	3.8	-0.6	-1.3	-0.5	-4.0	1.1	3.1	2.5	2.5	3.4	1.6	1.4	0.9	1.2	1.0	2.5	4.3	2.5	4.5	0.5
Smoking status: Previous	1.2	1.8	12.8	0.6	1.2	0.5	-0.8	-1.6	-1.4	-3.6	-0.7	0.7	1.4	1.6	-0.6	-0.8	-0.5	-1.4	-1.2	-1.7	0.8	-1.7	1.6	-0.1	-0.1
Asthma (self-reported)	1.2	2.4	5.7	-1.9	-2.4	-2.1	-1.3	-1.8	1.0	-2.0	-1.8	-1.9	-1.1	-0.6	-1.5	-1.2	1.2	2.1	0.9	-0.1	1.3	-0.4	-1.1	-2.4	1.2
Ever depressed for a whole week	1.2	1.4	8.5	0.7	1.0	0.3	2.9	2.2	1.8	1.1	1.4	0.2	0.2	0.7	0.3	0.2	-1.7	-1.3	0.3	0.7	-1.0	-0.2	1.0	0.3	-1.4
Vascular/heart problems diagnosed by doctor	1.2	3.1	16.4	1.6	2.0	2.1	0.1	1.2	-0.7	0.5	-1.1	2.0	2.7	1.3	0.6	2.4	0.6	0.9	0.1	-4.1	2.8	0.1	0.4	1.9	-2.6
Alzheimer’s Disease (in mother)	1.1	1.3	4.8	0.6	1.6	1.5	1.0	-0.7	-1.4	-0.8	-0.5	1.2	1.3	-0.3	1.9	0.0	-2.2	-0.8	0.8	0.9	0.1	1.4	0.6	1.4	-1.6
Crohns Disease (2017)	1.1	2.4	7.6	1.8	0.7	1.4	0.3	1.4	0.5	-0.3	1.3	0.9	0.9	-1.2	2.0	0.5	2.8	2.6	2.2	1.3	1.2	2.3	0.5	2.5	-1.5
Verbal and Numeric Reasoning (VNR)	1.1	2.6	13.6	-1.5	-1.1	-1.1	-3.1	-3.0	1.6	-3.7	-1.9	-1.4	-1.4	-1.1	-0.6	-1.8	1.5	0.9	-0.5	0.6	0.0	0.2	-0.8	0.2	-0.4
Bipolar Disorder (2011)	1.1	1.1	8.1	-0.2	0.7	-0.2	0.5	-0.2	-2.8	-1.4	-1.6	-0.1	-0.1	0.8	-0.8	0.3	0.3	0.7	-1.0	-2.1	-0.6	-1.4	-0.8	0.2	-0.4
Respiratory disease	1.1	2.5	6.7	-1.4	-2.1	-1.9	-0.7	-1.3	0.5	-2.4	-2.6	-1.9	-1.1	-1.2	-1.6	-0.8	1.5	2.5	1.4	0.1	1.1	-0.4	-1.5	-2.5	1.2
Lung FEV1/FVC ratio	1.1	5.8	17.4	3.9	3.5	3.4	0.6	1.5	0.7	0.8	3.2	4.2	2.1	2.3	2.4	3.3	0.6	-0.6	0.1	-0.5	1.2	2.3	2.9	3.8	-0.2
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	11.2	-0.2	-1.2	-1.4	-0.2	0.8	0.1	3.3	1.7	-0.2	-0.8	-1.8	-0.9	1.7	1.1	1.4	-1.1	-0.3	-0.7	-0.7	-0.9	0.5	0.7
Trunk fat percentage	1.1	4.4	23.9	1.4	0.9	0.3	-0.9	-1.0	1.9	-3.6	-1.2	0.5	1.4	-2.6	1.4	0.9	3.5	4.9	2.5	-0.8	2.9	2.8	-1.3	1.4	0.5
Current tobacco smoking	1.1	1.8	6.3	0.0	-0.8	0.0	-0.0	0.0	-1.7	-1.0	1.8	-0.2	-0.2	-1.2	0.9	0.5	1.5	2.2	0.7	2.3	-1.8	2.5	-1.1	1.9	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	7.2	1.7	0.6	0.7	0.2	0.5	0.8	1.3	1.5	0.3	0.8	-1.3	1.0	-0.0	1.8	1.7	2.7	1.6	0.8	1.7	0.6	0.4	0.2
Age when periods started (menarche)	1.1	2.5	7.4	-2.1	-1.1	-1.4	-2.4	-0.8	-1.6	2.2	0.2	-0.8	-1.3	0.3	-1.4	-0.3	-0.8	-1.4	-2.7	-2.7	-0.3	-2.6	-1.4	-1.9	0.0
High blood pressure	1.1	3.2	17.0	-1.4	-2.1	-2.1	-0.6	-1.6	0.4	-0.3	0.8	-1.9	-2.7	-1.4	-0.8	-1.6	-0.1	-0.7	-0.6	4.1	-3.4	0.2	-0.6	-1.4	2.8
Forced expiratory volume in 1-second (FEV1)	1.1	3.8	11.0	2.6	2.5	2.7	-1.5	0.6	-1.2	-0.2	1.0	2.6	1.2	1.8	2.6	3.3	1.0	0.7	1.5	1.0	1.6	3.3	1.5	2.8	1.4
Pulse wave Arterial Stiffness index	1.1	1.3	4.8	-0.8	-1.0	-0.6	1.0	-0.4	0.7	-1.9	-1.2	-1.9	-1.5	-1.3	-0.0	-1.4	-0.0	1.0	1.2	2.2	-0.9	0.2	-0.3	-1.1	-0.4
Medication: Amlodipine	1.1	1.5	9.7	-0.3	-0.8	-0.7	-0.3	0.2	1.5	-0.1	1.9	-0.7	-1.5	0.9	0.6	-0.5	-0.8	-1.3	0.4	3.1	-1.6	0.1	0.8	-0.5	2.4
Birth weight	1.1	2.3	7.3	-2.7	-1.1	-1.7	-1.3	-2.6	0.8	-1.4	-2.5	-1.9	-2.0	0.4	-0.9	-1.8	-0.6	0.6	-1.4	-0.6	-0.6	-1.2	-1.9	-1.3	-0.2
Pulse rate, automated reading	1.1	3.5	19.3	1.9	-0.3	-0.5	-0.1	3.0	2.6	4.4	2.5	0.7	-0.4	-1.3	1.2	3.1	1.8	1.9	1.1	1.1	0.5	1.1	-0.4	0.5	2.8
Leg pain on walking	1.1	1.3	5.1	-0.4	-1.3	-1.2	-0.1	-1.6	2.3	-0.5	-1.3	-1.6	-1.9	-0.4	-1.6	-0.8	-0.7	-0.3	-1.3	0.6	-1.3	-0.5	-1.0	-0.5	1.1
Smoking status: Current	1.1	1.8	5.9	-0.2	-1.0	-0.2	0.1	0.0	-1.7	-1.0	1.7	-0.2	-0.4	-1.1	0.8	0.2	1.6	2.2	0.8	2.4	-1.5	2.3	-1.0	1.8	1.7
Alcohol drinker status: Never	1.1	1.4	5.3	1.5	1.1	1.1	1.6	-0.1	0.1	-0.5	-0.2	1.4	1.5	1.3	0.9	-0.3	-2.3	-2.3	0.4	-1.0	1.0	-0.4	1.0	-1.2	-0.7
Diastolic blood pressure, automated reading	1.1	3.6	17.8	0.1	-2.1	-1.7	-1.2	2.1	1.8	3.3	-0.6	-1.1	-1.8	-1.4	-1.0	1.7	1.3	1.3	1.2	3.4	-1.2	1.7	-1.2	-0.0	4.2
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	4.2	1.2	1.3	1.7	-0.5	-1.3	0.5	-1.3	1.1	1.2	1.5	1.1	2.0	-1.0	-0.4	-0.2	1.6	0.5	1.5	1.4	1.3	-0.3	-0.1
Worry (Nagel 2018)	1.0	2.1	7.6	1.6	1.5	2.1	2.0	2.0	-0.0	-0.9	1.2	1.2	1.7	0.8	1.4	0.2	-1.4	-1.2	1.8	0.8	0.4	0.3	2.1	0.7	-2.8
Irritable Bowel Disease (IBD)	1.0	2.4	8.6	2.1	1.1	1.4	1.2	1.4	-0.6	0.6	1.5	1.3	1.4	-0.7	2.2	1.1	2.9	2.1	1.5	0.6	0.6	1.8	1.0	2.6	-1.2
Crohns Disease (2012)	1.0	1.6	4.1	1.7	0.7	1.4	1.2	1.9	-0.1	0.5	1.1	0.8	0.4	-0.5	2.0	0.4	1.7	1.7	1.7	1.4	0.3	1.5	0.3	1.7	-1.2
Blood Red Count	1.0	9.3	33.2	-2.7	-3.6	-4.3	-0.6	0.8	2.3	4.0	-0.6	-3.4	-3.5	-3.9	-2.2	1.3	3.8	5.8	2.2	1.1	0.3	0.9	-4.5	-3.1	3.6
Blood White Count	1.0	7.2	35.3	1.5	1.9	1.6	0.9	2.4	-0.4	-0.5	0.9	2.1	3.6	-0.7	1.3	1.0	5.9	5.9	5.1	-0.8	3.9	2.6	0.9	0.8	-1.0
Vitamin and mineral supplements	1.0	1.4	5.4	-0.1	-0.7	-0.5	0.2	0.7	1.1	1.9	1.2	-0.6	-1.0	-1.9	1.3	0.2	1.9	2.3	1.2	1.2	0.1	1.7	-0.8	0.2	0.1
Medication: Metformin	1.0	1.5	5.3	-1.2	-1.8	-1.7	-0.7	0.1	0.9	-0.0	-0.3	-1.1	-1.3	-1.0	-2.3	-1.3	0.4	0.7	-0.3	-0.8	-0.8	-1.5	-1.8	-2.0	0.9
Severe depression (siblings)	1.0	1.1	5.0	1.1	1.3	1.2	0.7	-0.0	-0.7	-0.1	1.7	1.2	0.4	0.9	1.5	0.4	0.0	-1.4	-0.4	0.2	0.3	0.4	1.9	2.2	-0.3
Trunk fat mass	1.0	4.3	19.1	1.8	1.4	1.1	-1.2	-1.9	1.9	-4.4	-1.3	0.6	1.4	-1.9	1.8	0.6	2.8	3.9	2.4	-0.2	2.9	3.1	-0.4	1.8	0.2
Heart attack	1.0	1.3	4.9	-1.8	-0.8	-1.6	0.2	-0.3	-0.1	-0.1	-1.2	-1.1	-0.3	-0.5	-1.0	-1.2	-0.9	0.4	-0.6	-1.9	0.7	-1.6	-1.9	-2.2	0.5
Diabetes (self-reported)	1.0	1.5	5.3	-1.1	-1.7	-1.7	-1.4	-0.7	0.3	-0.8	-0.8	-1.8	-1.4	-1.5	-2.3	-0.7	0.7	0.8	-0.0	-0.2	-0.6	-0.7	-1.6	-1.9	0.4
Father’s age at death	1.0	1.4	7.4	-1.1	-1.2	-1.2	-2.0	-0.2	0.0	-1.3	-1.7	-0.7	0.1	-0.0	-1.6	0.1	1.0	0.2	-1.3	-2.7	-0.1	-0.9	-1.8	-0.6	0.0
Medication: Lansoprazole	1.0	1.1	6.0	-0.2	-1.0	-1.0	-0.7	-0.5	0.0	1.0	-0.0	-1.3	-1.0	-2.0	-0.2	-0.5	0.5	0.7	1.1	2.4	-0.2	0.7	-0.6	-0.8	2.0
Prospective memory result	1.0	1.2	3.5	-0.5	-1.6	-1.2	1.0	-0.8	0.6	-1.2	-0.2	-1.4	-1.8	1.0	-0.4	-1.2	-1.2	-0.1	0.2	1.6	-1.1	-1.2	-0.0	-1.3	1.9
Hair/balding pattern: Pattern 4	1.0	2.5	10.8	2.1	2.5	2.9	1.0	0.5	-0.3	-0.5	0.7	1.3	2.2	-0.2	0.9	1.4	-2.1	-1.8	0.8	-1.3	0.7	1.2	1.5	0.5	-3.3
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	5.0	0.7	1.5	1.0	-0.2	1.6	-0.4	0.1	1.9	2.0	1.9	2.2	1.5	1.2	1.7	0.2	-0.3	-2.0	1.3	0.2	1.5	2.2	-0.7
Body fat percentage	1.0	4.0	19.5	1.8	1.2	0.6	-0.4	-0.9	2.2	-3.4	-1.2	0.6	1.5	-2.3	1.3	1.2	3.2	4.4	2.2	-1.1	2.5	2.6	-1.1	1.5	-0.1
Exposure to tobacco smoke outside home	1.0	1.4	6.4	-1.2	-1.2	-0.9	-2.2	-2.5	-0.5	-2.4	-0.6	-0.3	-0.6	-0.0	-0.7	-0.5	1.1	1.6	-0.4	-0.7	0.6	0.7	-1.6	-0.4	0.3
Angina (self-reported)	1.0	1.4	8.5	1.3	1.0	0.5	2.9	2.0	1.3	-0.1	1.9	0.9	0.7	0.9	0.9	-0.5	-0.5	0.5	1.7	0.5	1.2	0.1	0.9	0.1	-0.1
Hypertension (Self-reported)	1.0	2.9	21.5	-0.8	-1.7	-1.6	-0.3	-1.0	0.6	-0.2	1.3	-1.7	-2.3	-1.3	-0.5	-1.8	-0.5	-1.2	0.1	4.6	-3.2	0.4	0.1	-1.3	2.4
Medication for cholesterol	1.0	1.5	12.7	-0.6	-0.2	-0.7	0.3	0.7	-0.4	0.8	-1.3	-0.1	0.2	0.5	-1.0	1.5	0.4	1.5	-1.3	-3.6	0.2	-0.9	-2.0	0.2	-1.7
Eye problems/disorders: Glaucoma	1.0	1.2	5.0	0.4	-0.3	-0.4	0.3	0.4	-1.0	1.1	0.4	-0.8	-1.0	-1.7	0.4	1.8	1.3	1.7	-0.9	-0.6	-2.2	0.8	-1.7	0.9	-0.5
Myopia	1.0	1.4	10.3	-0.5	0.2	0.1	-0.4	0.6	-0.4	1.1	1.1	1.1	0.8	3.2	0.2	0.0	-0.8	-1.5	-1.8	-2.0	-0.5	-2.0	0.3	-0.1	-0.5
Basal cell carcinoma (self-reported)	1.0	1.1	14.7	0.2	-0.3	-0.2	-0.8	-0.5	3.8	0.4	-0.4	-0.7	-0.3	-0.3	-0.7	-0.9	-1.1	-0.7	-0.6	0.7	-1.1	-1.1	-0.3	-0.1	-1.4
Heart attack/myocardial infarction (self-reported)	1.0	1.3	4.3	-1.7	-0.7	-1.7	0.3	-0.2	-0.4	0.0	-1.2	-1.1	-0.4	-0.4	-1.1	-1.0	-0.9	0.4	-0.7	-2.1	0.6	-1.6	-1.9	-2.1	0.5
Alcohol drinker status: Previous	1.0	1.1	3.9	-1.8	-1.6	-1.0	-2.0	-0.7	0.1	-0.1	-1.0	-0.9	-1.6	0.7	-1.5	-1.3	0.1	0.5	-0.3	-0.3	-0.2	-0.7	-1.4	-1.2	0.2
Intelligence (Savage-Jansen 2018)	0.9	2.7	11.9	-2.0	-1.3	-1.0	-3.5	-2.8	0.9	-3.0	-1.9	-1.2	-1.3	-1.4	-0.8	-2.0	2.2	1.2	-0.8	0.4	0.1	-0.5	-1.0	-0.1	-0.8
Schizophrenia vs Biploar Disorder	0.9	1.2	7.3	-0.2	-0.5	-0.2	-0.8	-0.0	2.4	0.4	0.1	0.6	0.5	-0.2	-0.3	0.7	1.4	2.7	1.4	-0.2	1.8	0.3	-0.3	0.3	1.6
Breast Cancer	0.9	2.3	14.7	0.2	0.9	1.1	-1.2	1.0	0.1	-0.3	1.5	1.1	0.5	3.0	0.1	-0.7	-2.6	-3.8	-0.9	-0.1	-0.0	-1.5	2.7	0.5	-0.8
Prostate Cancer	0.9	1.3	5.6	1.5	0.8	1.3	0.6	0.2	-0.8	-0.7	1.4	0.1	-0.1	-1.7	1.9	-0.1	0.2	-0.4	1.5	2.4	-0.3	1.9	1.6	-0.3	0.3
Cardiovascular Disease	0.9	3.1	24.7	-0.7	-1.3	-0.8	-0.6	-1.4	1.8	-0.5	1.4	-0.6	-1.9	1.2	0.9	-2.3	-0.9	-2.0	0.9	5.0	-1.7	0.2	1.6	-1.1	3.0
Average weekly spirits intake	0.9	1.1	3.8	1.3	1.1	1.3	0.5	0.0	0.2	-0.4	-0.9	1.2	1.4	-0.5	2.0	0.3	1.1	1.4	1.1	-0.8	1.4	1.7	-0.2	0.8	-1.0
Relative age of first facial hair	0.9	1.8	7.6	-0.9	-0.5	-0.8	-0.9	-1.0	1.4	-0.8	-0.5	-0.4	-0.3	2.5	-0.8	-2.2	-1.7	-2.6	-0.6	-0.3	-0.0	-2.8	1.0	-1.5	0.8
Angina	0.9	1.2	8.2	1.2	0.9	0.4	2.9	2.0	1.4	-0.2	1.6	0.8	0.5	0.8	0.7	-0.8	-0.7	0.3	1.5	0.5	1.0	-0.1	0.8	0.1	0.1
High blood pressure (mother)	0.9	1.3	6.1	-0.2	-0.9	-0.2	-0.7	-1.6	2.5	-0.9	0.7	-1.4	-2.0	-0.0	-1.3	-1.0	-1.3	-1.4	-0.9	0.7	-1.0	0.3	-0.3	-0.8	-1.6
Past tobacco smoking	0.9	1.7	15.0	-0.3	-0.6	-0.3	0.9	1.5	2.0	3.9	-0.1	-0.9	-1.1	-1.3	0.5	0.7	-0.2	1.1	1.5	1.0	-0.2	1.5	-1.4	-0.4	-1.1
Lung cancer (father)	0.9	1.0	3.6	0.1	-0.2	0.1	-0.3	-0.1	-0.8	-0.5	0.7	0.5	0.8	-1.9	1.7	0.2	1.9	1.7	0.8	0.9	1.2	1.6	0.1	0.6	0.5
Length of working week for main job	0.9	0.9	3.2	-1.0	-1.3	-0.8	0.9	-1.1	1.6	-0.1	-0.8	-1.0	-1.0	0.5	-0.4	-0.9	-0.5	-0.1	-0.6	-0.2	-1.1	-1.5	-1.2	-1.8	0.6
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	9.0	-0.2	-0.2	0.1	0.4	-1.6	1.4	-0.3	0.7	-0.4	-0.7	0.5	-0.4	-1.6	-1.7	-3.0	-1.9	-1.4	-0.8	-2.2	0.5	0.1	-0.9
Forced vital capacity (FVC), Best measure	0.9	3.1	8.8	2.2	2.4	2.5	-1.9	1.0	-1.5	-0.1	0.5	2.0	1.4	2.2	2.1	3.0	0.5	0.3	1.5	0.4	1.6	2.8	1.0	2.5	0.7
Comparative body size at age 10	0.9	2.6	16.3	-0.3	1.8	1.4	1.2	-2.9	0.0	-2.3	-0.1	0.1	0.6	0.7	0.9	-2.5	-1.1	-2.1	-1.4	-1.8	-0.4	-0.8	1.0	-0.1	-4.0
Mouth/teeth dental problems: Loose teeth	0.9	1.1	3.9	0.9	0.7	1.1	1.4	0.8	0.3	0.0	1.7	0.9	0.9	1.0	1.4	-0.0	-0.6	-0.7	1.1	2.0	-0.1	0.9	1.3	1.5	0.7
Whole body fat mass	0.9	3.9	16.9	2.1	1.8	1.4	-0.8	-1.8	1.9	-4.1	-1.1	0.9	1.6	-1.6	1.7	0.9	2.3	3.3	2.0	-0.6	2.5	2.9	-0.2	2.1	-0.4
Leg fat mass (right)	0.9	3.5	14.2	2.5	1.9	1.9	-0.4	-1.5	2.0	-3.8	-0.8	1.0	1.5	-1.4	1.7	1.3	1.9	2.6	1.8	-0.2	1.9	3.1	0.3	2.2	-0.6
Handedness (chirality/laterality): Left-handed	0.9	1.1	3.9	-0.5	-0.5	-0.7	-1.3	0.2	0.5	-0.2	-0.7	-0.5	-1.1	0.5	-2.0	0.2	-1.4	-2.0	-1.7	-1.3	-1.0	-1.3	-0.5	-1.1	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	8.3	-1.2	0.1	-0.3	0.8	0.2	-1.3	0.4	-0.4	-1.2	-0.6	-0.5	-1.3	0.3	0.5	0.4	-0.7	-2.0	-0.6	-0.7	-1.4	-0.4	-2.9
Breast cancer (self-reported)	0.9	1.0	3.5	-0.5	-0.7	-1.5	-0.2	1.1	0.1	1.9	0.3	-0.8	-0.9	-0.3	-1.5	-0.5	-0.9	-1.4	-0.9	0.9	-1.5	-0.9	-0.1	-1.3	1.4
Average weekly beer plus cider intake	0.9	1.2	4.2	0.9	1.2	1.8	1.0	-0.9	-0.5	-0.8	-0.2	0.5	1.1	2.0	1.6	-0.1	-0.9	-1.4	-1.4	-0.3	-1.0	0.0	1.2	1.0	-1.6
Irritability	0.9	1.4	16.2	1.0	1.1	1.4	1.5	-0.2	-0.9	-1.6	-0.0	-0.0	1.1	0.3	0.2	0.1	-0.0	-0.6	-0.3	-0.8	-1.6	0.2	0.1	0.7	-4.0
Cholesterol lowering medication	0.9	1.4	6.6	0.4	0.9	1.0	-0.6	0.6	-1.1	-0.5	0.8	1.6	1.1	-0.3	0.7	0.3	1.1	0.8	2.6	1.3	2.1	1.2	1.4	0.2	1.6
Supplements: Calcium	0.9	1.0	4.4	0.6	0.5	0.1	0.4	0.0	-0.8	-2.1	-0.1	0.5	0.2	0.8	0.7	-1.4	-0.9	0.1	1.7	2.0	1.4	1.0	0.9	0.3	1.1
Heart disease (siblings)	0.9	1.1	5.4	-1.9	-0.6	-1.1	0.1	-0.5	0.2	-0.1	-0.1	-0.4	-0.4	-0.8	0.0	-2.3	1.3	1.5	0.4	-0.8	1.8	-1.4	-0.8	-1.2	0.5
Leg fat mass (left)	0.9	3.6	15.6	2.4	1.9	1.9	-0.5	-1.8	1.8	-4.0	-1.1	0.9	1.4	-1.6	1.6	1.0	2.0	2.7	1.9	-0.0	1.9	3.1	0.3	2.0	-0.8
Bipolar Disorder (2018)	0.8	1.3	8.1	-0.3	0.0	-0.8	-0.6	-0.8	-2.9	-1.8	-2.0	-0.8	-1.4	1.2	-1.2	0.1	0.1	0.0	-1.0	-1.2	-0.4	-1.2	-0.6	-0.7	1.0
HDL Cholesterol	0.8	1.4	10.1	-1.0	-0.4	-1.4	1.1	2.1	0.1	3.2	0.9	-0.2	-0.9	-0.3	-0.2	0.2	1.3	2.0	0.3	-0.4	0.4	-1.1	-0.5	-1.6	0.2
Ulcerative Colitis	0.8	1.1	5.3	1.4	0.6	0.8	2.3	1.0	-1.7	0.5	1.3	0.7	0.6	0.2	1.5	1.1	0.8	-0.2	0.7	1.2	-0.6	0.4	1.4	1.3	0.5
Blood Eosinophil Count	0.8	6.0	17.1	2.5	4.0	3.9	0.9	0.8	-1.5	-2.8	1.2	3.1	4.0	1.6	2.8	-0.0	2.0	0.3	2.0	-0.7	2.4	0.9	4.1	2.8	-2.4
Height	0.8	14.6	52.0	3.0	3.5	4.4	-6.0	-1.7	-2.1	-5.8	-0.2	3.0	2.9	0.7	3.5	3.0	3.4	3.3	3.0	1.4	5.8	7.2	2.1	4.8	4.3
Type 2 Diabetes (T2D) (2018)	0.8	1.4	3.0	-1.4	-1.5	-1.2	-1.4	-1.5	1.2	-1.1	-1.3	-1.3	-1.2	-0.7	-1.7	-1.4	0.0	0.9	-0.2	-0.2	-1.1	-0.7	-1.7	-1.6	0.3
Pack years adult smoking proportion	0.8	1.2	6.9	1.0	0.0	0.3	0.4	0.5	-1.1	0.5	-0.1	0.0	0.8	-0.6	1.3	1.0	1.2	2.2	1.7	1.0	-0.6	2.6	-1.1	1.1	0.3
Sitting height	0.8	5.4	25.2	2.6	2.9	3.7	-2.5	-2.3	-1.9	-3.4	-0.7	1.2	1.9	0.1	2.6	0.9	0.7	1.2	2.4	1.3	2.3	5.0	1.7	2.7	-0.5
Waist circumference	0.8	2.9	13.9	2.0	1.7	1.4	0.2	-1.9	1.4	-3.7	-0.5	0.8	1.1	-1.8	1.6	0.3	1.5	2.0	2.1	1.4	1.6	3.1	0.8	1.6	0.4
Medication: Ramipril	0.8	1.0	5.3	-0.1	-0.9	-0.9	-0.6	0.0	-1.6	0.1	-0.1	-0.3	-0.2	-2.3	-0.8	0.9	0.9	1.2	-0.5	-0.6	0.0	0.2	-1.9	-0.9	2.0
Medication: Simvastatin	0.8	1.1	10.0	-0.7	-1.1	-1.1	0.1	0.3	-1.7	0.0	-0.4	-0.3	0.1	-0.2	-0.3	-0.2	0.7	1.0	1.9	1.1	0.5	1.2	-0.8	-0.4	3.2
Weight	0.8	4.1	23.5	2.1	2.1	2.1	-1.3	-2.8	2.3	-4.8	-0.9	0.9	1.3	-0.4	2.5	-0.4	0.8	1.5	1.9	1.5	2.0	3.4	1.2	2.1	0.0
Depression (self-reported)	0.8	0.9	4.6	1.1	-0.3	0.1	0.8	0.1	-1.3	0.8	-0.3	-0.6	0.0	-1.4	0.8	0.0	0.2	1.2	2.1	1.4	0.4	1.7	-0.9	0.1	1.0
Impedance of arm (left)	0.8	3.5	18.7	-0.7	-0.7	-1.3	-1.4	1.1	-1.4	0.6	0.2	0.8	0.9	-0.2	-0.1	1.5	3.6	4.3	1.2	-3.1	3.5	-0.1	-1.9	-0.1	2.5
Glaucoma (self-reported)	0.8	1.0	4.1	0.1	-0.4	-0.8	0.5	0.7	-0.4	1.7	0.6	-0.8	-0.7	-2.0	0.2	1.4	1.1	2.0	0.1	-0.5	-0.9	0.7	-1.6	-0.2	0.1
Leg fat percentage (right)	0.8	3.0	10.7	2.0	1.1	1.1	-0.0	-0.5	2.4	-3.1	-0.8	0.6	1.0	-2.4	1.0	1.7	2.5	3.3	1.5	-0.6	1.2	2.6	-0.6	1.8	-0.3
Wheeze or whistling in the chest in last year	0.8	1.4	4.4	0.0	-1.2	-0.4	-1.9	-1.3	1.7	-1.7	-1.8	0.0	1.3	0.4	-0.3	-1.0	2.1	2.1	0.6	0.6	0.0	0.8	-0.5	0.0	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	9.7	-0.2	-1.0	-0.6	0.3	0.1	-0.2	-0.3	-0.2	-0.6	-1.0	-0.9	0.2	0.2	-0.4	-0.3	0.4	3.1	-1.7	0.5	0.1	0.4	2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	2.6	-1.3	-1.2	-1.4	-1.6	0.5	0.7	0.8	-0.3	-0.9	-1.0	-1.1	-0.9	-0.3	1.3	1.4	-0.3	-0.1	0.1	-0.2	-1.5	-1.1	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	7.2	1.5	2.1	2.6	-0.2	-0.6	-1.2	-0.6	0.1	0.8	1.1	1.2	1.4	1.7	0.0	0.4	1.2	1.2	0.8	2.7	0.6	1.9	-0.4
Average weekly red wine intake	0.8	1.2	3.7	0.2	1.2	1.6	0.3	-0.1	0.6	0.7	1.3	1.4	0.6	1.1	-0.4	-0.4	-1.6	-1.9	0.1	-0.6	1.4	-0.6	1.9	0.4	-1.8
Miserableness	0.8	1.4	4.6	-2.0	-1.6	-1.3	-1.6	-0.3	0.2	-0.1	0.4	-0.7	-1.1	0.4	-1.4	-2.0	0.3	-0.0	-1.1	-0.6	-1.4	-2.1	-1.2	-1.3	-0.4
Guilty feelings	0.8	1.2	5.6	-0.2	0.2	0.7	0.1	-1.2	0.4	-2.2	-0.3	-0.3	0.1	1.6	0.1	-1.7	-2.4	-1.8	0.1	1.3	-0.0	-0.4	1.3	-0.2	-0.5
Wears glasses or contact lenses	0.8	0.9	3.5	-0.4	-0.1	-0.7	-1.4	0.8	-1.3	0.7	0.1	0.9	0.5	-0.5	-1.6	1.1	0.5	0.4	-0.1	-1.9	1.2	-1.4	-0.1	-0.8	1.3
Mother’s age at death	0.8	1.0	3.1	-1.3	-1.2	-0.9	-0.9	-1.6	0.9	-0.6	-1.4	-0.5	0.1	-0.2	-1.0	-1.3	-0.3	0.1	-1.1	-1.7	0.6	-1.2	-1.3	-1.1	-0.5
High cholesterol (Self-reported)	0.8	1.4	8.5	-1.6	-1.6	-1.9	-1.3	-0.5	-0.8	-0.7	-1.4	-0.7	-1.1	-1.0	-1.3	-0.4	0.4	0.3	0.3	0.4	0.6	-0.5	-0.7	-1.4	2.9
Medication: Atorvastatin	0.8	1.0	3.7	1.1	0.6	0.6	-0.9	-1.0	1.2	-1.5	-0.3	0.6	-0.2	0.5	-0.2	0.5	-1.4	-1.9	0.0	1.4	0.4	-0.4	1.9	-0.2	1.1
Ever smoked	0.8	1.4	13.6	0.6	1.0	0.8	-0.6	-1.0	-1.6	-3.7	0.6	1.1	1.4	0.9	0.2	-0.6	0.3	-1.1	-1.2	-0.8	-0.3	-0.6	1.2	1.1	0.8
Leg fat percentage (left)	0.8	3.0	11.7	2.0	1.1	1.0	0.1	-0.7	2.2	-3.1	-1.1	0.4	1.0	-2.8	1.0	1.3	2.8	3.4	1.6	-0.4	1.1	2.5	-0.7	1.4	-0.8
Risk taking	0.8	1.1	10.3	-0.2	-0.5	-0.1	0.5	-1.8	-3.2	-0.5	0.1	-1.0	-0.7	0.5	0.5	0.1	-1.5	-0.7	-1.6	0.8	-1.4	-0.1	0.0	-0.0	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.8	0.9	3.5	-1.0	-0.9	-0.6	0.4	0.3	0.5	0.9	0.8	-0.7	-0.7	-1.9	0.2	-1.1	1.7	1.8	0.8	1.1	0.5	0.7	-0.8	-1.2	0.3
Ulcerative Colitis (UC)	0.7	1.3	4.6	1.4	0.9	0.8	1.6	1.0	-1.6	1.0	1.1	0.9	1.2	-0.1	1.7	1.3	2.1	1.0	0.9	0.2	-0.1	0.9	1.0	1.4	-0.6
Smoking Status	0.7	1.7	9.7	0.7	-0.2	0.1	-0.4	-0.5	-1.9	-3.1	1.5	0.5	0.9	0.1	0.9	-0.1	0.5	0.7	0.6	2.0	-0.4	1.4	0.8	1.9	2.6
Allergy or Eczema	0.7	1.8	7.1	-1.1	-0.4	-0.6	0.5	-0.8	1.6	-2.0	-1.5	-1.1	-0.9	0.8	-1.7	-1.8	-1.8	-1.6	-0.7	-1.1	-0.5	-2.7	-0.1	-1.4	-1.4
Ever used hormone-replacement therapy (HRT)	0.7	0.8	2.7	0.2	0.6	0.6	-1.1	0.6	-1.3	0.2	0.9	1.6	1.6	-1.0	0.3	0.1	0.6	-0.5	0.6	0.9	1.3	0.3	1.5	1.1	0.7
Stomach or abdominal pain in last month	0.7	0.9	3.6	-0.8	0.3	0.4	-0.1	-1.0	-1.8	-0.8	1.5	1.2	1.2	0.7	-0.1	0.2	0.0	-1.3	-1.2	-1.9	0.8	-0.8	0.6	0.2	-0.5
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	3.5	-0.9	-1.1	-0.7	-0.8	-0.6	0.5	-1.8	-0.3	-0.2	-0.7	-0.0	-1.2	-1.2	-1.0	-0.8	-1.4	-1.0	-0.8	-1.9	-0.2	-0.0	-0.5
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	3.4	-0.3	-0.1	-0.5	1.9	1.1	1.0	1.7	1.4	0.1	-0.2	1.2	0.5	-0.3	-0.8	-0.8	-0.1	0.3	-0.4	-1.3	0.4	-0.5	-1.0
Hip circumference	0.7	3.1	14.7	2.2	2.3	1.6	-0.9	-1.9	2.3	-3.8	-0.4	1.3	1.9	-0.0	2.2	-0.1	0.9	1.1	1.6	0.2	2.0	2.6	1.2	1.7	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.9	1.2	0.4	0.3	-0.3	1.0	-1.6	1.7	1.3	0.7	0.3	0.7	0.8	0.2	0.7	-0.4	0.3	1.2	-0.5	0.5	0.5	0.2	1.7
Mouth/teeth dental problems: Bleeding gums	0.7	1.0	2.6	0.2	0.6	-0.1	0.1	-1.3	-1.0	1.6	1.4	1.6	0.9	0.8	1.6	1.4	0.9	1.0	-0.6	0.4	1.0	0.4	0.1	1.0	0.8
Headache pain in last month	0.7	1.2	5.4	-0.3	-1.1	-0.6	0.1	-1.0	1.6	-1.3	-0.6	-1.1	-0.6	-0.0	-0.3	-2.3	-1.5	-1.5	-0.7	0.5	-1.2	-1.4	0.3	-1.4	-1.1
Chronic bronchitis/emphysema (mother)	0.7	0.8	3.6	-1.0	0.1	0.1	-0.5	0.3	0.7	1.0	0.1	1.3	0.9	1.1	-0.2	-1.1	0.2	0.8	-1.1	-1.9	0.8	-1.1	-1.0	0.6	-0.9
Medication: Blood pressure	0.7	1.3	5.6	0.7	-0.3	-0.6	0.5	0.6	-1.8	0.9	1.8	-0.4	-0.9	-0.9	0.9	1.0	-0.7	-1.0	-0.3	2.3	-1.5	1.0	0.5	0.4	2.4
Mean time to correctly identify matches	0.7	1.3	4.0	-0.7	-0.7	-0.8	0.6	-0.1	0.4	-0.6	-2.0	-1.2	-0.9	-1.5	-1.8	-0.6	-0.9	-0.2	-0.8	-1.1	-1.9	-1.0	-1.4	-1.5	-1.3
Arm predicted mass (right)	0.7	3.4	11.5	1.8	1.9	2.6	-1.2	-2.6	0.6	-3.4	-0.2	1.0	0.8	0.6	2.2	-0.6	-0.9	-0.9	1.5	2.8	1.0	3.1	2.2	2.2	0.2
Suffer from ‘nerves’	0.7	1.1	7.0	0.7	0.5	1.7	-0.6	-0.5	0.4	-2.6	0.8	1.0	1.3	-0.4	1.5	-0.9	1.0	0.6	0.4	0.2	0.8	0.9	0.8	0.8	-1.6
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.8	1.2	0.8	0.9	1.9	-0.5	-0.5	-0.7	0.1	0.5	0.4	0.4	1.7	-0.1	-1.0	-1.5	-0.6	0.6	-0.5	-0.1	0.8	0.2	-0.7
Arm fat percentage (left)	0.7	2.7	13.7	1.2	0.8	-0.2	0.0	-1.3	2.3	-3.1	-0.8	0.1	0.9	-2.0	0.8	0.3	2.7	3.7	2.0	-1.0	2.1	1.5	-0.8	0.8	-0.0
Ever had bowel cancer screening	0.7	0.8	4.4	-0.5	0.4	0.4	-0.1	0.7	0.2	-2.1	-0.7	-0.1	0.1	-1.0	0.2	-1.4	-1.4	-1.4	-0.5	-1.0	1.1	-0.5	0.3	-0.8	-1.0
Eye problems/disorders: Cataract	0.7	0.8	2.4	-0.3	0.1	-0.9	-0.7	-0.2	1.2	0.8	-0.8	0.3	0.3	-0.9	-1.6	-1.1	0.9	0.4	-0.5	-1.5	0.8	-1.5	-0.4	-1.2	-0.9
Number of self-reported non-cancer illnesses	0.7	1.3	8.9	0.6	-0.8	-0.7	0.3	1.0	1.9	-0.0	0.3	-1.0	-0.3	-3.0	-0.3	0.4	1.7	1.7	1.6	0.5	0.1	0.8	-0.1	-1.1	-0.9
Number of operations (self-reported)	0.7	1.1	6.7	0.4	0.5	0.6	-1.3	0.1	-1.2	-2.2	-0.4	-0.0	-0.2	-2.6	-0.4	0.8	1.0	1.1	0.0	1.1	0.4	1.4	0.2	1.1	-0.0
Pack years of smoking	0.7	1.0	4.2	0.7	-0.1	-0.2	0.6	1.1	-1.1	0.7	0.1	0.1	0.8	-0.9	1.0	1.0	1.2	2.1	1.5	0.3	-0.4	1.9	-1.2	0.7	0.3
Depression (Nagel 2018)	0.6	0.9	3.2	0.9	0.4	0.8	-0.7	-0.2	0.3	0.5	1.0	0.6	1.0	-1.0	0.8	-1.4	1.5	1.1	1.8	1.5	0.6	1.2	0.6	0.1	-0.1
Neuroticism (Nagel 2018)	0.6	1.5	4.4	1.3	1.2	1.7	1.5	1.6	-0.7	-1.0	1.6	1.0	1.3	0.3	1.1	-0.2	-0.4	-0.2	2.1	1.3	0.1	1.2	1.5	0.6	-1.9
Alzheimer’s Disease (including proxy)	0.6	0.8	6.7	-0.6	0.4	0.2	0.5	-0.5	-2.6	-0.7	0.4	0.4	0.9	-1.0	1.5	0.0	-0.9	0.2	0.5	1.2	-0.1	1.2	-0.4	0.8	-0.9
Age at First Birth	0.6	0.8	2.7	1.0	1.4	0.9	1.2	0.5	0.4	-0.3	-0.5	1.0	1.2	1.0	1.3	0.2	-1.1	-0.8	0.7	0.8	0.3	0.3	1.6	0.7	-0.8
Fasting Glucose	0.6	0.7	5.9	1.1	-0.5	-0.2	-0.0	0.3	-0.1	2.4	0.8	1.0	1.0	-0.6	-0.3	0.8	0.0	0.4	0.1	-1.1	-0.7	-0.3	-0.6	1.1	1.2
LDL Cholesterol	0.6	1.0	3.3	-1.1	-1.2	-1.5	-0.5	0.8	0.6	1.7	0.1	-0.3	-0.5	0.1	-1.0	1.0	0.2	0.8	0.1	-1.8	0.7	-0.9	-1.8	-0.5	1.3
Primary Biliary Cirrhosis	0.6	0.8	5.3	0.6	0.3	0.5	-0.3	0.3	-0.0	1.2	0.8	0.4	-0.3	1.0	0.4	-0.4	-0.6	-2.3	-1.2	-0.7	0.5	-1.9	1.3	0.5	0.1
Triglycerides	0.6	0.9	6.9	0.7	0.8	1.1	-0.4	-0.7	1.8	-2.6	-0.5	0.8	0.9	-0.1	0.6	-0.2	0.0	-0.7	0.7	0.0	1.1	1.4	0.5	1.1	0.2
Diabetes (mother)	0.6	0.8	3.7	0.0	-1.2	-0.9	1.0	-0.1	0.5	0.0	-1.9	-0.9	-0.6	-0.6	-1.6	0.0	-0.6	0.7	0.3	0.5	-0.3	1.0	-1.4	-1.0	1.2
Impedance of leg (right)	0.6	2.9	12.3	0.7	-0.0	0.8	-1.5	1.7	-1.8	0.8	-0.3	1.4	0.9	-0.9	-0.1	3.5	2.9	3.3	-0.4	-2.7	1.2	1.1	-1.9	1.8	1.2
Leg fat-free mass (left)	0.6	3.0	13.4	1.3	1.8	1.6	-0.9	-2.8	1.4	-3.7	-0.3	0.6	0.8	1.3	2.2	-0.8	-0.5	-0.1	1.9	2.0	1.9	2.5	2.1	1.6	0.8
Bilateral oophorectomy (both ovaries removed)	0.6	0.6	3.5	-0.6	-0.9	-0.4	-1.0	-0.7	0.6	-0.8	-0.1	-0.5	-0.7	-1.7	-1.2	-1.1	0.2	-0.2	0.4	1.9	0.1	-0.2	0.3	-0.3	0.5
Hayfever, allergic rhinitis or eczema	0.6	1.3	3.7	-0.2	-0.2	-0.0	0.5	-0.7	1.7	-1.8	-1.4	-0.5	-0.3	1.1	-1.1	-1.9	-1.8	-1.9	-0.4	-0.6	-0.4	-1.8	0.6	-0.8	-1.4
Impedance of leg (left)	0.6	2.7	10.5	0.9	0.1	1.0	-1.3	1.6	-2.1	0.9	-0.4	1.4	1.0	-1.1	0.0	3.2	3.2	3.2	-0.0	-2.5	1.1	1.0	-1.8	1.5	0.5
Had menopause	0.6	0.7	5.4	-0.5	-0.2	0.0	-1.3	-0.1	-0.8	-1.2	-0.4	0.5	1.2	-2.3	-0.3	-1.0	1.2	0.5	-0.1	-0.3	1.3	-0.3	-0.0	0.1	-0.5
Had other major operations	0.6	0.8	2.5	-0.3	0.1	-0.4	-1.6	-0.3	-1.5	-0.9	-0.3	-0.8	-0.9	-1.0	-0.6	1.1	1.4	0.9	-0.8	0.4	-1.0	0.9	-0.7	0.2	1.1
Forced vital capacity (FVC)	0.6	2.4	7.5	1.5	1.7	2.0	-2.4	0.3	-1.7	-0.4	0.3	1.6	0.9	1.3	2.0	2.2	0.4	0.2	1.3	1.3	1.2	2.7	0.9	2.2	1.5
Impedance of arm (right)	0.6	2.8	16.9	-0.4	-0.3	-0.9	-1.1	1.6	-0.7	0.4	-0.0	0.7	0.9	0.1	-0.2	1.9	3.3	4.1	0.8	-3.0	2.8	-0.0	-1.7	0.2	1.9
Arm fat percentage (right)	0.6	2.4	12.3	1.1	0.8	-0.2	0.1	-1.1	2.9	-3.3	-1.0	-0.2	0.6	-2.0	0.4	0.3	2.3	3.5	1.6	-0.9	1.3	1.3	-0.9	0.8	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	5.1	0.9	-0.3	0.4	-0.2	-0.1	-0.3	1.4	1.2	0.7	0.8	0.0	0.7	0.2	2.0	2.2	1.1	1.0	-0.4	1.0	-0.1	1.1	0.3
Medication: Cholesterol lowering	0.6	0.9	5.6	-1.1	-1.3	-1.8	-0.1	-0.7	-0.7	-0.7	-1.0	-0.8	-0.9	0.2	-1.1	-0.4	-0.4	0.1	0.0	-0.1	0.1	-0.8	-0.9	-1.3	2.4
Arm fat mass (right)	0.6	2.6	14.7	1.8	1.5	1.0	-0.3	-1.8	2.5	-3.8	-0.8	0.3	0.9	-1.3	1.6	0.1	1.5	2.3	1.6	0.5	1.2	2.3	0.2	1.7	-0.2
Standing height	0.6	5.8	19.6	1.5	2.0	2.8	-4.4	-2.8	-0.5	-3.9	-0.6	2.0	1.4	1.9	2.4	0.7	1.1	1.4	1.2	1.1	3.6	3.8	1.6	3.0	2.8
Exposure to tobacco smoke at home	0.6	0.7	3.3	-0.8	-0.8	-0.7	-0.6	-1.8	1.7	0.5	-0.1	-0.3	-0.5	-0.4	0.4	-0.4	0.4	1.2	-1.4	-0.7	-0.2	-0.1	-1.4	0.5	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	5.0	0.6	0.6	0.5	2.2	1.1	0.4	-0.6	2.0	0.9	0.7	0.8	1.0	0.1	-0.4	0.0	0.9	-0.8	1.1	-0.4	0.6	0.3	-1.4
Ever highly irritable/argumentative for 2 days	0.6	0.7	4.6	0.1	0.2	0.1	0.9	1.1	1.4	1.5	1.1	0.0	-0.0	-0.9	0.1	-0.6	-0.0	1.1	0.3	-0.8	-0.7	-0.5	-0.3	0.1	-2.1
Medication: Paracetamol	0.6	0.9	6.5	0.2	0.5	0.6	-0.1	-1.3	1.5	-2.5	-0.9	0.6	1.0	0.5	1.0	-1.3	0.3	-0.1	0.2	0.3	1.1	-0.1	0.9	0.0	-1.2
Arm fat-free mass (right)	0.6	3.3	10.2	1.9	2.0	2.7	-1.3	-2.8	0.5	-3.2	-0.3	1.2	0.9	0.9	2.2	-0.4	-1.2	-1.3	1.1	2.4	1.2	2.9	2.3	2.4	0.2
Migraine (self-reported)	0.6	0.7	5.8	0.6	0.8	0.9	0.4	-0.6	-1.0	-1.2	-1.1	-1.1	-0.2	-0.8	0.2	0.0	-0.5	-0.2	0.4	0.2	-0.6	1.0	0.5	0.1	-2.4
Medication: Omeprazole	0.6	0.7	2.8	-0.5	-0.6	-0.3	0.3	0.7	0.6	1.5	0.9	-0.1	-0.5	-1.7	0.4	-0.8	1.2	1.3	0.5	1.4	0.6	0.6	-0.4	-0.8	0.2
Medication: Seretide 50 evohaler	0.6	0.7	3.7	0.5	0.5	0.7	-1.5	-1.9	-0.3	-1.2	-1.3	0.4	0.8	1.0	0.3	-0.5	-0.4	-0.3	0.3	0.3	1.3	1.2	0.2	-0.2	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	2.2	1.1	1.0	0.7	0.4	-0.1	0.6	1.1	1.5	1.3	1.3	0.3	0.8	0.6	-0.1	-0.3	0.0	-1.2	0.9	0.0	0.2	1.1	-1.3
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	5.8	-0.9	1.1	0.4	1.1	1.0	0.5	-0.6	0.3	0.7	0.8	0.7	-0.1	-0.0	-0.7	-0.8	-0.1	-1.4	0.4	-0.6	0.8	0.6	-2.4
Loneliness, isolation	0.6	0.8	3.0	-0.4	-1.0	-0.7	0.3	-0.6	0.5	0.3	1.3	-1.3	-1.4	-0.6	-0.4	-1.5	-1.0	-0.4	0.8	1.7	-0.5	0.4	0.3	-1.4	0.0
Long-standing illness, disability or infirmity	0.6	0.9	3.2	-1.0	-1.7	-1.2	-1.5	-0.2	0.4	1.6	1.8	-0.7	-1.2	-0.6	-0.9	-0.8	-0.2	-0.2	-0.1	0.1	-0.0	-1.0	-0.8	-1.3	-0.5
Arm fat mass (left)	0.6	2.5	15.1	1.7	1.5	0.9	-0.4	-1.9	2.4	-3.9	-0.8	0.5	0.9	-1.0	1.5	0.0	1.5	2.2	1.5	0.0	1.6	2.1	0.2	1.6	-0.1
Commuting to job workplace: Public transport	0.6	0.7	5.0	0.7	-0.1	0.2	-0.2	1.0	0.6	2.2	0.5	0.7	0.8	-0.4	0.2	1.6	-0.1	1.2	0.9	-0.1	0.6	0.9	-0.3	1.2	0.6
Basal metabolic rate	0.6	3.3	15.2	1.7	2.0	2.1	-1.2	-2.9	1.4	-3.9	-0.5	0.7	0.6	1.1	2.2	-0.5	-0.6	-0.3	1.4	2.3	1.2	2.9	2.0	2.1	0.6
Arm fat-free mass (left)	0.6	3.2	14.0	1.6	1.8	2.4	-1.3	-2.6	1.6	-3.7	-0.8	0.6	0.4	0.7	1.8	-0.6	-1.4	-1.1	0.7	2.9	0.0	2.8	1.9	2.3	0.3
Pain experienced in last month	0.6	1.0	6.2	-0.6	-0.4	-0.7	-1.8	0.7	-1.0	0.8	-0.2	0.4	-0.1	2.3	-0.2	0.2	-0.9	-1.0	-0.7	-0.5	0.4	-0.6	-0.1	-0.2	2.5
Impedance of whole body	0.6	3.1	15.5	0.3	-0.3	-0.1	-1.3	1.9	-1.7	1.0	0.2	1.3	1.1	-0.4	0.2	2.7	3.6	3.9	0.6	-2.7	2.4	0.6	-1.8	0.9	1.7
Arm predicted mass (left)	0.6	3.2	13.8	1.8	1.8	2.4	-1.5	-2.7	1.3	-3.7	-1.0	0.6	0.4	0.6	1.7	-0.3	-1.3	-0.9	0.9	2.8	0.2	3.0	1.8	2.1	0.3
Ovarian Cancer	0.5	0.6	2.4	0.5	-0.2	-0.0	0.7	1.2	-0.3	0.1	1.2	-0.6	-0.3	-0.1	-0.7	0.3	-1.2	-1.5	0.3	1.5	-0.3	0.4	0.9	-0.5	1.4
Neuroticism (2016)	0.5	0.7	3.8	-0.0	0.3	0.5	0.6	0.7	-1.4	-1.9	0.1	0.5	0.7	-0.6	0.5	-0.4	0.5	1.4	1.4	0.1	1.0	0.9	0.2	-0.4	-0.8
Type 2 Diabetes (T2D) (2012)	0.5	0.5	1.7	0.2	-0.6	-0.8	-1.1	-0.7	0.9	-0.2	-0.2	-0.8	-0.9	-0.5	-1.1	-0.8	-0.5	-1.0	-1.3	0.5	0.2	0.1	0.3	-1.1	0.5
BMI	0.5	3.0	19.0	1.6	1.3	1.6	0.2	-2.2	3.4	-4.4	-2.0	0.0	0.8	-1.9	0.8	-1.2	-0.1	0.6	1.5	0.8	0.2	1.6	0.4	0.0	-2.7
Systolic Blood Pressure	0.5	2.7	11.4	-1.0	-1.9	-1.2	-0.4	1.3	0.9	1.9	0.6	-0.0	-1.3	2.5	-1.4	-0.8	-1.3	-2.3	0.1	3.4	-2.2	-0.8	0.9	-0.5	3.2
Hypothyroidism (self reported)	0.5	1.2	6.6	-0.1	0.7	0.4	0.0	1.3	0.5	-0.0	1.8	1.2	0.6	2.6	1.4	1.1	1.1	0.2	-0.7	-1.6	0.7	0.0	0.8	1.9	-0.3
Tanning	0.5	6.1	20.6	2.2	2.1	1.9	-0.6	1.4	-3.0	1.3	3.2	3.7	3.4	1.2	2.4	2.7	2.5	2.3	2.3	-0.8	4.5	2.7	1.8	3.2	0.9
Medication for hormone replacement therapy	0.5	0.6	3.6	1.1	0.7	1.0	-0.2	-0.3	-1.9	0.9	0.2	0.2	0.6	-0.9	0.4	0.6	0.0	-0.5	-0.6	0.8	-0.4	0.7	0.8	1.2	0.1
Medication: Co-codamol	0.5	0.6	3.0	-1.0	-0.3	-0.2	-0.2	-1.7	0.5	-1.2	-0.7	-0.7	-0.7	-0.2	-0.2	-1.7	-0.3	0.2	-0.1	0.8	-0.0	-0.1	-0.2	-1.0	-0.5
Medication: Levothyroxine sodium	0.5	0.8	2.5	0.1	0.5	0.3	-1.3	1.2	0.5	0.0	1.1	1.3	1.0	1.5	0.5	0.7	1.0	0.3	-0.8	-1.3	0.6	-0.1	0.8	1.6	-0.1
Leg predicted mass (left)	0.5	2.8	13.0	1.2	1.7	1.5	-1.0	-2.8	1.4	-3.6	-0.2	0.5	0.7	1.2	2.1	-0.8	-0.5	-0.1	1.9	2.0	1.8	2.4	2.0	1.5	0.9
Alcohol usually taken with meals	0.5	0.9	4.3	0.6	-0.0	0.4	-1.3	1.0	-1.1	2.1	0.7	0.5	0.4	-1.0	-0.6	-0.4	0.6	0.5	1.6	-0.2	1.8	0.4	0.1	-0.9	-0.6
Financial difficulties in last 2 years	0.5	0.7	3.4	-0.2	-1.0	-0.1	-1.8	-1.2	0.0	-1.4	0.1	-0.7	-0.6	0.5	-0.1	-1.7	-0.5	0.4	0.3	0.7	-0.2	0.3	-0.8	0.1	1.0
Mouth/teeth dental problems	0.5	0.8	5.4	-0.7	-0.6	0.1	-1.1	0.5	0.7	-0.4	-0.9	-1.2	-0.4	-2.3	-0.9	-0.5	0.0	0.6	0.3	-0.5	-0.8	0.1	-0.5	-0.7	-1.8
Fluid intelligence score	0.5	1.0	6.5	-0.9	-0.5	-0.3	-1.7	-1.2	0.6	-2.5	-1.2	-0.6	-0.7	-0.7	0.5	-1.1	0.8	0.7	0.9	1.9	0.3	0.7	0.1	0.3	-0.2
Trunk fat-free mass	0.5	2.8	11.3	1.2	1.7	2.0	-1.5	-2.8	1.0	-3.4	-0.5	0.5	-0.0	1.6	1.6	-0.6	-1.6	-1.4	0.5	2.5	0.4	2.2	2.1	1.9	0.7
Alcohol intake versus 10 years previously	0.5	0.8	2.0	-0.4	-1.1	-1.0	-1.0	-0.8	1.1	-1.4	-0.8	-1.2	-0.6	-0.7	-1.0	-0.2	1.0	1.3	-0.3	0.3	-0.9	0.5	-1.3	-0.1	0.1
Falls in the last year	0.5	0.7	1.9	1.1	0.5	0.9	-1.3	-1.1	0.0	-0.7	0.3	0.9	1.3	0.1	0.1	0.3	0.5	0.6	0.1	-1.4	1.3	1.2	-0.4	0.9	-0.0
Illnesses of mother	0.5	0.6	4.3	-0.4	-0.3	-1.1	0.5	1.2	0.2	0.9	1.2	0.0	-0.4	-0.4	0.2	0.8	0.8	0.3	-0.4	-0.4	-0.3	-0.7	-0.0	-0.7	2.1
Trunk predicted mass	0.5	2.8	11.3	1.2	1.6	2.0	-1.5	-2.8	1.0	-3.4	-0.6	0.5	-0.1	1.6	1.6	-0.6	-1.6	-1.5	0.5	2.5	0.3	2.2	2.0	1.9	0.8
Peak expiratory flow (PEF)	0.5	1.3	5.0	0.8	0.2	0.6	-1.9	-1.3	-0.8	-0.2	0.0	0.9	-0.2	-0.0	1.2	1.4	1.5	1.3	0.4	1.2	1.0	1.9	0.1	1.1	2.2
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	7.4	0.5	1.0	1.4	0.1	0.5	0.7	0.2	-0.6	0.7	1.4	-0.2	-0.1	0.2	0.6	1.1	0.8	-1.5	1.1	0.1	0.0	0.2	-2.7
Gout (self-reported)	0.5	0.6	3.1	-0.4	-0.5	-0.1	-0.7	-1.4	0.2	-0.1	-0.2	-0.7	-1.2	0.6	-0.4	-0.5	-0.8	-0.3	-1.5	-0.3	-1.8	-0.5	-0.4	0.4	-0.9
Medication: Ventolin 100micrograms inhaler	0.5	0.7	2.2	0.1	-0.7	-0.6	-0.3	0.1	0.1	1.1	-0.6	-0.2	0.4	-1.5	-1.2	1.1	1.3	1.2	0.7	-1.0	0.9	0.0	-0.9	-0.4	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.7	-0.2	-0.9	-0.5	1.6	-0.1	-0.6	-0.4	1.2	-0.3	-0.0	-0.2	-0.2	-1.7	-0.8	-0.1	0.6	-0.4	-0.1	-1.1	-0.3	-0.7	-1.2
Number of children fathered	0.5	0.6	3.0	0.7	0.6	0.1	0.8	-0.2	0.6	0.3	0.5	-0.2	-0.5	1.3	0.3	1.3	-0.4	-1.7	-1.4	-0.3	-1.2	-0.4	0.6	-0.1	0.4
Neck or shoulder pain in last month	0.5	0.7	3.1	-0.5	-0.7	-1.0	0.2	-0.3	0.8	0.4	-0.1	-1.2	-1.4	-0.5	-1.3	-0.3	-1.2	-0.4	-0.3	-0.5	0.0	-1.3	-0.1	-1.8	-0.5
Medication: Allopurinol	0.5	0.6	2.0	-0.3	-0.6	0.3	-1.1	-1.3	1.0	-0.6	-0.5	0.2	-0.5	1.2	-0.7	-0.6	-1.3	-0.8	-1.4	-0.4	-1.0	-0.8	0.3	0.3	-0.0
Alcohol intake frequency.	0.5	1.2	4.0	-1.0	-2.0	-1.6	-0.6	-0.2	1.6	0.9	0.1	-1.3	-1.2	-0.3	-1.3	-1.1	0.2	0.3	0.2	-0.6	0.4	-0.4	-1.9	-1.9	0.5
Age at last live birth	0.5	0.7	4.2	0.5	0.6	0.3	-0.0	-0.8	-1.2	0.2	-1.4	-1.2	-0.9	0.2	-0.5	-0.0	-0.5	-2.0	-0.8	-0.4	-1.4	-0.5	-0.1	-0.6	-1.1
Medication: Aspirin	0.5	0.6	2.7	-0.9	-0.3	-0.6	-0.1	-0.7	-0.3	-1.0	0.0	-0.8	-0.6	-0.5	0.0	-1.6	-1.6	-1.1	-0.3	0.7	-0.7	-0.5	-0.2	-0.9	0.8
Whole body fat-free mass	0.5	3.1	12.0	1.5	2.0	2.1	-1.1	-2.8	1.1	-3.5	-0.3	0.8	0.5	1.5	2.1	-0.6	-1.1	-0.9	1.3	2.5	1.0	2.7	2.2	2.0	0.6
Leg fat-free mass (right)	0.5	2.8	12.4	1.2	1.8	1.5	-0.8	-2.9	1.3	-3.5	-0.2	0.5	0.7	1.5	2.2	-1.2	-0.7	-0.5	1.9	2.1	1.6	2.1	2.1	1.3	0.5
Friendships satisfaction	0.5	0.7	4.5	-0.0	1.5	0.3	2.1	-0.1	-0.8	-0.0	1.4	0.8	-0.3	0.7	1.0	0.1	-0.4	-0.2	0.0	-0.2	0.3	0.2	1.4	0.4	0.2
Qualifications: nursing, teaching	0.5	0.8	5.5	-0.1	-0.1	0.0	-0.4	-1.0	0.9	0.4	-0.2	0.3	0.3	1.2	0.2	-0.5	-0.2	-1.1	-1.9	-2.3	0.5	-1.6	-0.5	-0.7	-0.2
Commuting to job workplace: Walk	0.5	0.6	2.2	1.0	0.0	0.8	-0.4	0.3	0.8	0.2	0.5	0.9	0.8	0.2	0.4	0.8	-0.5	0.5	1.0	1.2	0.3	1.4	0.3	1.5	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	7.0	1.3	0.9	0.7	-1.1	1.7	1.2	-0.4	-0.9	0.6	1.1	-0.9	0.6	2.6	0.6	0.6	1.0	-0.6	0.6	1.0	-0.2	0.4	-0.1
Whole body water mass	0.5	3.1	12.5	1.4	1.9	2.0	-1.1	-2.8	1.1	-3.5	-0.3	0.7	0.4	1.5	2.0	-0.7	-1.2	-1.0	1.3	2.6	1.0	2.5	2.2	1.9	0.8
Leg predicted mass (right)	0.5	2.7	13.1	1.1	1.6	1.4	-0.9	-3.0	1.2	-3.6	-0.3	0.3	0.6	1.4	2.1	-1.4	-0.7	-0.5	1.8	2.2	1.5	2.1	2.1	1.2	0.6
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.0	0.1	-1.0	-0.3	0.2	0.4	1.4	0.1	1.2	-0.3	-1.1	-1.3	-0.1	-1.0	0.0	-0.1	0.9	1.2	0.4	-0.1	0.0	-0.8	1.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.6	-0.2	-0.6	-0.3	-0.8	-0.6	0.2	-0.9	-0.5	-0.8	-0.6	0.2	-0.1	0.0	-1.6	-0.9	0.4	1.4	0.0	0.8	0.3	-1.1	1.1
Age started oral contraceptive pill	0.5	0.7	2.7	0.5	1.1	0.5	0.8	1.1	1.1	-0.7	0.5	1.1	1.3	0.0	0.7	-0.1	-0.0	0.3	1.1	-0.3	1.6	0.2	0.9	0.6	-0.8
Unable to work because of sickness or disability	0.5	0.6	3.2	-0.1	0.1	0.0	-1.1	-0.7	-0.1	-0.6	0.9	0.8	0.4	1.8	0.8	-0.4	1.0	0.9	0.7	-0.1	1.6	0.2	0.1	-0.0	0.9
Reaction Time	0.4	0.8	5.0	0.3	-0.0	0.3	0.7	0.1	0.3	-0.4	-0.6	0.2	-0.2	1.3	-0.6	0.2	-1.7	-1.6	-1.1	-0.6	-2.2	-1.1	0.0	-0.2	-0.6
Mean Putamen Volume	0.4	0.4	1.7	0.4	0.5	0.5	0.4	-0.2	0.3	0.1	0.9	-0.5	-0.9	-0.3	1.2	-0.4	0.7	0.4	1.3	1.1	0.0	0.6	-0.0	-0.4	-0.5
Lupus	0.4	0.6	3.5	-0.9	-0.4	-0.4	-0.1	-1.9	0.3	-0.6	0.2	-0.0	0.3	1.3	0.7	-1.7	-0.7	-1.2	-0.9	0.5	-0.2	-0.5	-0.2	-0.6	-0.1
Waist Hip Ratio (WHR)	0.4	1.8	10.3	0.1	-0.6	0.3	0.1	-0.7	-1.8	0.0	0.1	-0.1	-1.4	-1.6	0.2	1.0	1.2	1.8	1.1	3.2	0.2	2.5	-0.5	0.9	2.7
Neuroticism	0.4	0.9	4.0	-0.1	0.5	0.5	1.6	1.4	0.6	-1.1	0.9	0.2	0.8	0.6	0.4	-1.2	-0.3	-0.2	1.6	0.9	0.2	-0.5	1.0	-0.8	-2.0
Hand grip strength (left)	0.4	1.0	5.3	0.8	0.1	0.9	-0.6	0.1	-0.1	2.3	0.9	0.5	0.4	-0.3	1.7	0.5	0.0	0.4	-0.2	2.2	-1.0	1.5	0.2	1.4	-0.0
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.9	0.3	0.0	0.5	-0.0	-0.6	-0.6	-0.1	0.8	-0.1	0.0	-1.0	0.7	-1.3	1.4	1.1	0.7	1.0	-0.4	0.9	-0.2	-0.2	-0.9
Systolic blood pressure, automated reading	0.4	1.2	4.6	-0.7	-1.4	-1.1	-0.5	1.3	1.0	0.2	-0.7	-0.8	-1.3	-1.1	-2.1	-0.1	-0.3	-0.8	-0.0	1.8	-1.9	0.2	-0.3	-0.8	1.9
Hand grip strength (right)	0.4	1.0	5.4	0.7	0.6	1.2	-0.2	0.2	0.2	1.8	0.9	1.0	0.1	0.3	2.0	0.7	-0.3	0.3	0.5	2.3	-0.1	1.5	0.4	1.2	0.7
Average weekly fortified wine intake	0.4	0.4	2.2	-0.2	-0.5	-0.4	-1.5	-0.4	0.0	1.4	0.8	-0.7	-0.8	-0.3	0.0	0.7	1.0	0.7	-0.4	-0.5	-0.1	0.1	-0.5	0.3	-0.5
Chronic bronchitis/emphysema (father)	0.4	0.4	1.8	-0.7	-1.2	-0.9	-0.2	0.4	0.4	1.4	0.5	-0.2	-1.0	-0.1	-0.2	0.5	0.3	0.5	-0.3	-0.9	-0.3	-0.5	-1.2	-0.1	0.5
Body mass index (BMI)	0.4	1.7	9.8	1.4	1.2	0.8	0.7	-1.6	2.7	-3.1	-0.6	0.0	0.6	-1.3	1.3	-0.7	0.3	0.9	1.2	1.0	0.2	1.6	0.4	0.8	-1.2
Nervous feelings	0.4	0.8	3.9	-0.7	-0.7	-0.3	-0.6	-1.0	-0.6	-2.0	-0.3	-1.1	-0.7	-1.8	-0.9	-1.0	0.8	0.7	0.4	-0.0	0.2	0.1	-0.4	-0.9	-1.3
Allergy	0.4	0.9	3.4	0.3	0.8	0.5	0.3	1.2	-1.8	1.9	1.3	1.0	0.3	0.1	1.0	1.6	0.7	0.2	-0.7	0.2	-0.7	0.7	-0.3	1.5	0.7
Pain all over the body in last month	0.4	0.4	2.3	-0.6	-0.3	-0.1	-0.8	-1.5	-0.4	0.8	-0.2	-0.2	-1.3	0.4	-0.2	-0.3	-0.1	-0.2	-0.9	0.7	-1.2	-0.2	-0.5	0.5	0.2
Time employed in main current job	0.4	0.5	2.3	-0.4	-0.3	-0.6	-1.5	0.4	-0.6	-0.6	-0.8	-0.2	-1.0	0.2	-1.4	0.5	-0.3	0.1	-0.8	0.6	-0.8	-0.1	-0.1	-0.7	1.2
Happiness	0.4	0.5	2.4	-1.2	-0.9	-0.8	0.3	0.7	-0.1	1.5	0.3	-0.1	-1.2	-0.0	-1.3	-0.3	-0.5	0.4	-0.5	-0.2	-0.6	-0.6	-0.5	0.2	-0.2
Noisy workplace	0.4	0.5	1.6	0.2	-0.4	-0.8	0.7	0.3	0.6	0.9	0.2	-0.5	-1.3	-0.7	-0.5	-0.5	-1.0	-0.2	-0.7	1.2	-0.7	-0.2	0.1	0.1	1.2
Qualifications: A levels/AS levels or equivalent	0.4	0.9	4.7	-0.5	-0.0	-0.4	0.2	-0.5	0.4	0.4	-0.1	0.6	-0.6	2.2	-0.3	0.3	-0.2	-1.0	-2.1	-2.1	-0.2	-1.7	-0.4	0.3	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.7	-0.2	-1.1	-0.2	-1.3	-1.2	-0.4	0.4	-0.2	-0.0	-0.7	1.1	-0.2	-1.2	-1.1	-0.8	-1.0	0.6	-0.4	-0.5	-0.3	-0.3	0.3
Shortness of breath walking on level ground	0.4	0.5	1.8	0.6	0.4	0.3	1.3	0.7	1.3	0.5	0.0	0.5	0.4	0.3	0.5	0.2	-0.7	0.3	1.2	-0.6	1.1	0.3	0.5	-0.8	-1.3
Illnesses of siblings: Diabetes	0.4	0.4	1.8	0.4	-0.1	-0.1	-0.3	0.2	1.1	-0.4	-1.1	-0.4	0.5	-1.4	-0.8	-1.2	1.0	0.8	-0.3	-0.2	0.3	0.1	-0.5	-0.2	-0.7
Mood swings	0.4	0.7	7.0	0.4	0.8	0.9	1.0	0.3	-1.0	-1.3	0.0	-0.0	0.6	-1.0	-0.1	0.2	-0.3	-0.2	-0.1	-0.4	-0.8	0.4	0.1	0.7	-2.6
Osteoarthritis (self-reported)	0.4	0.5	2.0	0.6	0.8	0.9	-0.5	-0.9	0.2	-0.8	-0.7	0.4	0.2	-1.4	0.1	0.4	-0.4	-0.7	-1.3	-0.8	0.4	0.5	0.2	1.0	-1.1
Blood Platelet Count	0.3	3.7	10.4	-1.9	-1.9	-2.4	-0.6	-0.1	0.3	-1.3	-2.5	-2.2	-2.1	-1.7	-2.8	-2.9	1.9	2.0	-0.9	-0.1	-1.6	-2.5	-2.1	-3.2	0.3
Lung FVC	0.3	1.7	10.8	0.4	0.6	0.2	0.8	3.3	-1.6	3.1	1.1	-0.2	-0.7	-0.8	1.1	2.2	0.1	0.2	0.0	-0.0	-1.4	0.6	-1.1	0.2	-0.6
Hair Pigment	0.3	9.9	21.0	-4.6	-4.3	-3.5	-3.8	-2.2	-1.7	-0.2	-2.3	-4.3	-4.2	-3.2	-4.2	-3.7	1.4	0.1	-4.2	0.5	-3.5	-2.9	-3.1	-2.7	1.5
Number of treatments/medications taken	0.3	0.6	3.0	1.4	0.6	0.4	0.6	0.3	0.4	0.0	0.8	-0.2	0.2	-0.0	1.2	0.2	-0.2	-0.3	1.4	1.7	-0.1	1.3	1.0	-0.4	0.7
Maternal smoking around birth	0.3	0.5	1.7	1.0	-0.4	0.6	-0.4	0.3	-0.6	0.5	-0.0	0.5	-0.4	1.3	-0.2	1.2	-0.0	-0.2	-0.4	1.0	-1.1	-0.2	0.8	0.4	1.1
Taking other prescription medications	0.3	0.4	2.0	0.5	-0.7	-0.7	0.0	0.6	1.4	1.0	0.2	-0.5	-0.0	0.0	0.4	0.8	1.2	1.4	0.4	-0.2	0.3	0.2	-0.4	-0.5	0.5
Supplements: Glucosamine	0.3	0.4	1.5	0.6	0.5	0.4	-0.1	0.3	-0.5	1.1	0.3	0.7	0.9	-0.9	-0.8	0.0	-0.4	-1.1	-0.2	-0.7	1.2	-0.4	0.7	0.2	-0.5
Qualifications: None of the above	0.3	0.7	2.6	-0.2	-0.4	-0.5	-0.8	-0.1	-0.6	-0.8	-0.4	-0.9	-0.6	-1.1	-0.2	0.2	1.1	1.6	1.3	1.1	0.2	1.2	-0.3	-0.9	1.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.2	0.2	0.3	0.1	0.0	0.9	0.0	0.1	-0.7	-0.1	-0.0	-0.6	-0.4	0.5	1.3	1.2	1.5	-0.5	0.6	0.4	-0.2	-0.5	-1.1
Neuroticism score	0.3	0.6	2.1	0.2	0.5	0.6	1.4	0.4	-0.1	-1.2	1.1	0.1	0.5	0.4	0.7	-0.9	-0.1	-0.2	1.1	1.3	-0.4	0.1	0.9	-0.2	-1.2
Worry too long after embarrassment	0.3	0.6	2.2	0.0	-0.5	-0.8	0.4	0.9	0.6	1.0	0.7	-0.2	-0.3	-1.2	0.4	0.3	0.7	1.2	0.4	0.8	-1.2	-0.1	-0.4	-0.4	1.5
Age at first live birth	0.3	0.5	2.2	0.4	0.4	-0.3	0.4	0.6	-0.6	0.1	-0.6	-1.5	-1.0	-0.7	-0.6	0.4	-0.4	-0.9	-0.1	-0.9	-1.0	-0.3	-0.3	-0.9	-1.0
Health satisfaction	0.3	0.4	3.4	-0.6	-0.4	-0.4	-0.8	-0.4	-0.7	1.8	0.3	-0.1	-0.9	-0.9	-0.1	-0.0	0.2	0.8	0.4	0.1	-0.1	0.6	-0.6	-0.8	0.1
Emphysema/chronic bronchitis	0.3	0.4	1.5	-0.5	-0.9	-0.4	0.1	-1.2	-0.5	-0.4	0.2	-1.0	-0.4	-1.1	-0.3	0.3	0.3	0.7	-0.7	0.5	-0.8	-0.1	-0.4	-0.3	0.0
Medication for pain relief, constipation, heartburn	0.3	0.4	2.6	0.5	0.5	0.1	0.6	0.6	-1.1	1.4	-0.1	0.1	0.1	-0.0	-0.3	1.6	0.7	0.6	-0.1	-1.1	-0.3	0.3	-0.2	0.5	0.2
Overall health rating	0.3	0.6	4.8	0.4	-0.1	-0.1	0.3	0.8	-0.2	2.2	1.9	0.2	-0.1	0.9	0.6	0.4	-0.2	0.3	1.0	1.1	0.5	0.2	0.4	-0.0	0.6
Chest pain or discomfort	0.3	0.4	1.4	0.1	-0.7	-0.1	0.8	-0.6	1.2	1.0	0.8	0.5	0.2	0.3	0.5	-0.5	-0.5	-0.2	-1.1	-0.0	-0.3	-0.7	-0.5	-0.8	-0.1
Knee pain experienced in last month	0.3	0.5	2.4	-0.1	0.0	-0.2	0.5	-0.6	1.0	-0.7	-1.1	-0.5	-0.0	-1.1	-0.5	0.8	-0.4	-0.1	-0.3	-1.6	0.6	-0.0	-0.8	-0.9	-0.2
Back pain experienced in last month	0.3	0.4	4.1	0.3	0.8	0.7	0.7	-0.5	0.5	-0.3	0.6	-0.3	0.1	-0.5	0.5	0.4	0.6	-0.1	0.4	0.4	0.2	0.8	0.3	0.5	-2.0
Medication: Aspirin	0.3	0.4	2.0	-0.1	0.5	-0.1	0.6	-0.1	-0.6	-1.0	0.1	-0.4	-0.3	-0.1	0.8	-1.0	-1.4	-1.0	0.5	0.6	0.0	0.3	0.0	-0.7	0.5
Medication: Gliclazide	0.3	0.4	1.7	0.5	-0.2	-0.3	-0.3	0.9	0.7	-1.0	-0.6	-0.7	0.1	-0.9	-0.7	0.3	-0.4	0.3	1.3	0.5	-0.1	0.4	-0.0	-0.5	0.1
Illnesses of father: None of the above (group 1)	0.3	0.3	1.1	0.3	0.9	0.2	1.1	0.7	0.3	-0.7	-0.4	0.2	0.9	-0.0	0.6	-0.3	-0.2	0.1	0.7	0.2	0.9	0.7	0.5	0.2	-0.6
Financial situation satisfaction	0.3	0.4	1.3	-0.2	1.0	0.7	-0.3	-0.8	0.6	-0.7	-0.1	0.7	0.7	-0.8	0.1	-0.7	-0.1	0.9	0.8	-0.4	0.4	0.8	-0.2	-0.0	-1.1
Medication: Paracetamol	0.3	0.5	1.5	0.4	0.8	0.4	0.1	-0.3	1.0	-1.2	-0.8	0.8	1.0	0.9	1.1	-0.4	0.7	0.7	-0.1	0.2	0.9	0.1	0.5	0.1	-0.7
Depressed Affect (Nagel 2018)	0.2	0.3	1.4	-0.1	-0.3	0.0	-0.1	1.1	-0.6	0.4	0.6	-0.3	-0.2	-0.6	-0.5	-0.8	-0.0	0.1	0.6	1.0	-1.2	0.2	-0.2	-0.6	-0.8
Diabetes (father)	0.2	0.3	0.8	0.1	0.6	0.9	-0.8	0.2	0.3	0.7	-0.3	0.2	0.3	0.7	0.7	-0.1	-0.4	-0.5	0.2	-0.1	0.6	0.6	-0.2	-0.5	-0.9
Fed-up feelings	0.2	0.4	2.1	-0.1	-0.3	-0.3	0.6	0.3	0.0	-0.5	0.4	-0.5	-0.2	-0.3	0.5	-0.9	0.8	0.8	0.5	1.4	-1.0	1.0	-0.5	0.3	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.6	-0.4	-0.5	-0.1	0.1	-0.5	-0.6	0.3	-0.3	-0.2	0.5	0.6	-0.3	-1.0	0.9	0.5	-0.0	-0.4	-1.3	-0.7	-0.6	-0.1	-1.0
Qualifications: College or University degree	0.2	0.7	4.1	0.3	0.6	0.0	0.0	0.6	-1.2	0.5	-0.2	0.4	0.1	1.3	-0.5	1.5	0.1	-0.7	-1.6	-2.0	0.0	-1.2	0.3	0.6	-0.6
Medication: Ibuprofen	0.2	0.2	1.0	0.4	-0.6	0.0	-1.0	-0.9	-0.2	0.6	-0.3	0.3	-0.1	1.0	0.1	-0.6	-0.3	-0.1	-0.7	0.4	-0.1	0.3	-0.4	0.1	-0.1
Illnesses of father: Heart disease	0.2	0.2	1.4	0.2	-0.6	-0.2	-0.4	-0.8	-0.4	0.6	0.7	0.1	-0.3	-1.2	0.1	-0.2	0.0	0.1	-0.1	0.5	-0.2	0.1	-0.3	-0.3	0.7

Hub : Genes

SPTBN1

Models

Trait associations