Hub : Genes

SPTBN1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1010 0.0370 1.3e-03 0.018 NA 0.042 NA 0.035 1.2e-02 NA 2.4e-04 NA 7.1e-04
2 GTEx Artery Aorta 0.1700 0.0540 3.4e-05 0.091 NA 0.103 NA 0.091 1.1e-05 NA 2.7e-06 NA 1.1e-05
3 GTEx Artery Tibial 0.2094 0.0652 5.4e-07 0.138 NA 0.106 NA 0.148 6.2e-11 NA 1.1e-08 NA 1.1e-11
4 GTEx Brain Frontal Cortex BA9 0.2537 0.0948 1.0e-02 -0.003 NA 0.070 NA 0.005 4.1e-01 NA 6.5e-03 NA 2.3e-01
5 GTEx Breast Mammary Tissue 0.1960 0.0690 7.9e-04 0.000 NA 0.071 NA 0.020 3.2e-01 NA 1.7e-04 NA 3.1e-02
6 GTEx Breast Mammary Tissue (Male) 0.1868 0.0979 4.8e-02 -0.013 NA -0.005 NA -0.006 9.0e-01 NA 4.3e-01 NA 4.6e-01
7 GTEx Breast Mammary Tissue (Female) 0.1531 0.0883 4.6e-02 -0.007 NA -0.010 NA -0.005 6.1e-01 NA 1.0e+00 NA 4.7e-01
8 GTEx Esophagus Mucosa 0.1710 0.0530 1.1e-04 -0.002 NA 0.024 NA 0.016 5.0e-01 NA 9.0e-03 NA 2.7e-02
9 GTEx Esophagus Muscularis 0.2190 0.0560 6.0e-07 0.064 NA 0.110 NA 0.037 1.0e-04 NA 3.5e-07 NA 2.7e-03
10 GTEx Lung 0.0953 0.0343 1.2e-03 0.018 NA 0.049 NA 0.046 1.4e-02 NA 1.3e-04 NA 1.9e-04
11 GTEx Muscle Skeletal 0.1046 0.0348 7.9e-05 0.085 NA 0.095 NA 0.091 1.0e-08 NA 1.3e-09 NA 3.3e-09
12 GTEx Nerve Tibial 0.1560 0.0409 1.3e-06 0.005 NA 0.066 NA 0.061 1.3e-01 NA 2.0e-05 NA 3.7e-05
13 GTEx Thyroid 0.1390 0.0410 6.7e-05 0.014 NA 0.032 NA 0.033 2.8e-02 NA 1.7e-03 NA 1.3e-03
14 GTEx Whole Blood 0.1290 0.0370 6.0e-06 0.035 NA 0.077 NA 0.082 3.2e-04 NA 1.5e-07 NA 5.7e-08
15 NTR Blood 0.0631 0.0157 2.4e-12 0.036 0.043 0.042 0.045 0.043 9.4e-12 9.8e-14 1.9e-13 3.2e-14 1.0e-13
16 ROSMAP Brain Pre-frontal Cortex 0.1010 0.0287 9.1e-06 0.025 0.057 0.064 0.063 0.058 2.8e-04 6.7e-08 1.1e-08 1.6e-08 5.3e-08
17 TCGA Head and Neck Squamous Cell Carcinoma 0.0512 0.0237 2.3e-03 0.031 0.029 0.027 NA 0.023 1.7e-04 2.9e-04 4.9e-04 NA 1.1e-03
18 TCGA Brain Lower Grade Glioma 0.0979 0.0403 1.6e-05 0.039 0.041 0.044 NA 0.050 2.6e-05 1.9e-05 9.7e-06 NA 2.1e-06
19 TCGA Pheochromocytoma and Paraganglioma 0.1490 0.0740 4.3e-03 0.067 0.046 0.034 NA 0.049 1.2e-03 6.6e-03 1.7e-02 NA 5.2e-03
20 TCGA Prostate Adenocarcinoma 0.0631 0.0260 9.2e-06 0.043 0.053 0.047 NA 0.039 2.7e-05 3.1e-06 1.1e-05 NA 5.2e-05
21 TCGA Thyroid Carcinoma 0.0540 0.0300 3.2e-03 -0.002 0.009 0.020 NA -0.003 5.5e-01 3.9e-02 4.1e-03 NA 7.7e-01
22 TCGA Uterine Corpus Endometrial Carcinoma 0.3900 0.1270 3.6e-04 0.039 0.118 0.089 NA 0.085 2.9e-02 3.6e-04 1.8e-03 NA 2.3e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bipolar Disorder (2018) 0.8 1.3 8.1 -0.3 0.0 -0.8 -0.6 -0.8 -2.9 -1.8 -2.0 -0.8 -1.4 1.2 -1.2 0.1 0.1 0.0 -1.0 -1.2 -0.4 -1.2 -0.6 -0.7 1.0
Bipolar Disorder or Schizophrenia 1.3 3.1 11.6 -1.2 -1.1 -2.0 -1.6 -1.8 -1.3 -1.9 -3.4 -1.1 -1.6 0.8 -2.4 -0.1 0.9 1.9 -0.4 -2.5 1.5 -2.1 -1.4 -1.8 2.4
Depressed Affect (Nagel 2018) 0.2 0.3 1.4 -0.1 -0.3 0.0 -0.1 1.1 -0.6 0.4 0.6 -0.3 -0.2 -0.6 -0.5 -0.8 -0.0 0.1 0.6 1.0 -1.2 0.2 -0.2 -0.6 -0.8
Depression (Nagel 2018) 0.6 0.9 3.2 0.9 0.4 0.8 -0.7 -0.2 0.3 0.5 1.0 0.6 1.0 -1.0 0.8 -1.4 1.5 1.1 1.8 1.5 0.6 1.2 0.6 0.1 -0.1
Intelligence (Savage-Jansen 2018) 0.9 2.7 11.9 -2.0 -1.3 -1.0 -3.5 -2.8 0.9 -3.0 -1.9 -1.2 -1.3 -1.4 -0.8 -2.0 2.2 1.2 -0.8 0.4 0.1 -0.5 -1.0 -0.1 -0.8
Neuroticism (Nagel 2018) 0.6 1.5 4.4 1.3 1.2 1.7 1.5 1.6 -0.7 -1.0 1.6 1.0 1.3 0.3 1.1 -0.2 -0.4 -0.2 2.1 1.3 0.1 1.2 1.5 0.6 -1.9
Schizophrenia (2018) 1.3 2.6 7.5 -1.3 -1.4 -1.9 -1.6 -1.7 0.6 -1.0 -2.7 -0.8 -1.0 -0.0 -2.1 -0.2 1.1 2.5 0.3 -2.3 2.3 -1.7 -1.4 -1.7 2.2
Schizophrenia vs Biploar Disorder 0.9 1.2 7.3 -0.2 -0.5 -0.2 -0.8 -0.0 2.4 0.4 0.1 0.6 0.5 -0.2 -0.3 0.7 1.4 2.7 1.4 -0.2 1.8 0.3 -0.3 0.3 1.6
Worry (Nagel 2018) 1.0 2.1 7.6 1.6 1.5 2.1 2.0 2.0 -0.0 -0.9 1.2 1.2 1.7 0.8 1.4 0.2 -1.4 -1.2 1.8 0.8 0.4 0.3 2.1 0.7 -2.8
Alzheimer’s Disease (in mother) 1.1 1.3 4.8 0.6 1.6 1.5 1.0 -0.7 -1.4 -0.8 -0.5 1.2 1.3 -0.3 1.9 0.0 -2.2 -0.8 0.8 0.9 0.1 1.4 0.6 1.4 -1.6
Alzheimer’s Disease (in father) 1.8 1.9 6.1 -2.4 -2.5 -1.9 -1.0 -0.1 -0.3 0.0 0.2 -1.7 -0.9 -1.7 -1.9 -1.1 0.9 0.9 -0.7 0.0 -1.1 -1.5 -2.1 -1.8 0.8
Alzheimer’s Disease (including proxy) 0.6 0.8 6.7 -0.6 0.4 0.2 0.5 -0.5 -2.6 -0.7 0.4 0.4 0.9 -1.0 1.5 0.0 -0.9 0.2 0.5 1.2 -0.1 1.2 -0.4 0.8 -0.9
Crohns Disease (2017) 1.1 2.4 7.6 1.8 0.7 1.4 0.3 1.4 0.5 -0.3 1.3 0.9 0.9 -1.2 2.0 0.5 2.8 2.6 2.2 1.3 1.2 2.3 0.5 2.5 -1.5
Irritable Bowel Disease (IBD) 1.0 2.4 8.6 2.1 1.1 1.4 1.2 1.4 -0.6 0.6 1.5 1.3 1.4 -0.7 2.2 1.1 2.9 2.1 1.5 0.6 0.6 1.8 1.0 2.6 -1.2
Ulcerative Colitis (UC) 0.7 1.3 4.6 1.4 0.9 0.8 1.6 1.0 -1.6 1.0 1.1 0.9 1.2 -0.1 1.7 1.3 2.1 1.0 0.9 0.2 -0.1 0.9 1.0 1.4 -0.6
Major Depression (MDD) 1.8 2.2 5.1 -2.2 -1.7 -2.0 -1.6 -0.9 -0.2 0.6 -1.5 -1.8 -1.8 -0.7 -2.1 -1.5 -0.1 0.8 -1.3 -1.3 -1.4 -1.4 -2.3 -2.0 -0.8
Reaction Time 0.4 0.8 5.0 0.3 -0.0 0.3 0.7 0.1 0.3 -0.4 -0.6 0.2 -0.2 1.3 -0.6 0.2 -1.7 -1.6 -1.1 -0.6 -2.2 -1.1 0.0 -0.2 -0.6
Verbal and Numeric Reasoning (VNR) 1.1 2.6 13.6 -1.5 -1.1 -1.1 -3.1 -3.0 1.6 -3.7 -1.9 -1.4 -1.4 -1.1 -0.6 -1.8 1.5 0.9 -0.5 0.6 0.0 0.2 -0.8 0.2 -0.4
Breast Cancer 0.9 2.3 14.7 0.2 0.9 1.1 -1.2 1.0 0.1 -0.3 1.5 1.1 0.5 3.0 0.1 -0.7 -2.6 -3.8 -0.9 -0.1 -0.0 -1.5 2.7 0.5 -0.8
Ovarian Cancer 0.5 0.6 2.4 0.5 -0.2 -0.0 0.7 1.2 -0.3 0.1 1.2 -0.6 -0.3 -0.1 -0.7 0.3 -1.2 -1.5 0.3 1.5 -0.3 0.4 0.9 -0.5 1.4
Prostate Cancer 0.9 1.3 5.6 1.5 0.8 1.3 0.6 0.2 -0.8 -0.7 1.4 0.1 -0.1 -1.7 1.9 -0.1 0.2 -0.4 1.5 2.4 -0.3 1.9 1.6 -0.3 0.3
Age at First Birth 0.6 0.8 2.7 1.0 1.4 0.9 1.2 0.5 0.4 -0.3 -0.5 1.0 1.2 1.0 1.3 0.2 -1.1 -0.8 0.7 0.8 0.3 0.3 1.6 0.7 -0.8
Bipolar Disorder (2011) 1.1 1.1 8.1 -0.2 0.7 -0.2 0.5 -0.2 -2.8 -1.4 -1.6 -0.1 -0.1 0.8 -0.8 0.3 0.3 0.7 -1.0 -2.1 -0.6 -1.4 -0.8 0.2 -0.4
Body Mass Index (BMI) (2010) 1.3 1.7 7.7 1.2 1.1 1.4 0.7 -0.7 2.8 -2.3 -0.3 -0.7 0.6 0.4 0.8 -1.2 -1.7 -1.4 2.1 1.2 0.5 1.7 1.0 -0.3 -1.2
Coronary Artery Disease (CAD) 1.3 1.6 7.2 0.7 1.2 1.5 -0.8 0.3 -2.7 -0.2 2.0 1.5 1.9 0.3 2.0 0.6 0.4 -0.2 0.4 0.2 0.7 1.7 1.3 1.6 -0.6
Crohns Disease (2012) 1.0 1.6 4.1 1.7 0.7 1.4 1.2 1.9 -0.1 0.5 1.1 0.8 0.4 -0.5 2.0 0.4 1.7 1.7 1.7 1.4 0.3 1.5 0.3 1.7 -1.2
Mean Putamen Volume 0.4 0.4 1.7 0.4 0.5 0.5 0.4 -0.2 0.3 0.1 0.9 -0.5 -0.9 -0.3 1.2 -0.4 0.7 0.4 1.3 1.1 0.0 0.6 -0.0 -0.4 -0.5
Fasting Glucose 0.6 0.7 5.9 1.1 -0.5 -0.2 -0.0 0.3 -0.1 2.4 0.8 1.0 1.0 -0.6 -0.3 0.8 0.0 0.4 0.1 -1.1 -0.7 -0.3 -0.6 1.1 1.2
HbA1C 1.4 1.6 7.3 1.8 1.4 1.8 1.2 0.4 -0.8 -1.2 0.9 1.0 1.9 0.3 0.8 -0.7 0.5 0.9 1.9 0.1 0.9 2.7 0.4 1.5 0.6
HDL Cholesterol 0.8 1.4 10.1 -1.0 -0.4 -1.4 1.1 2.1 0.1 3.2 0.9 -0.2 -0.9 -0.3 -0.2 0.2 1.3 2.0 0.3 -0.4 0.4 -1.1 -0.5 -1.6 0.2
LDL Cholesterol 0.6 1.0 3.3 -1.1 -1.2 -1.5 -0.5 0.8 0.6 1.7 0.1 -0.3 -0.5 0.1 -1.0 1.0 0.2 0.8 0.1 -1.8 0.7 -0.9 -1.8 -0.5 1.3
Lupus 0.4 0.6 3.5 -0.9 -0.4 -0.4 -0.1 -1.9 0.3 -0.6 0.2 -0.0 0.3 1.3 0.7 -1.7 -0.7 -1.2 -0.9 0.5 -0.2 -0.5 -0.2 -0.6 -0.1
Neuroticism (2016) 0.5 0.7 3.8 -0.0 0.3 0.5 0.6 0.7 -1.4 -1.9 0.1 0.5 0.7 -0.6 0.5 -0.4 0.5 1.4 1.4 0.1 1.0 0.9 0.2 -0.4 -0.8
Primary Biliary Cirrhosis 0.6 0.8 5.3 0.6 0.3 0.5 -0.3 0.3 -0.0 1.2 0.8 0.4 -0.3 1.0 0.4 -0.4 -0.6 -2.3 -1.2 -0.7 0.5 -1.9 1.3 0.5 0.1
Rheumatoid Arthritis 1.5 2.0 6.9 1.9 1.0 1.4 0.4 0.9 -0.8 1.5 2.6 2.0 1.9 1.1 1.3 1.9 -0.4 0.1 1.2 1.2 1.4 1.1 1.9 1.8 0.4
Schizophrenia (2014) 1.9 4.1 11.4 -1.8 -1.8 -2.4 -2.3 -2.6 -0.0 -2.0 -3.2 -0.9 -1.5 0.3 -2.9 -0.2 1.2 2.5 -0.7 -3.4 1.9 -2.3 -2.0 -1.7 2.5
Triglycerides 0.6 0.9 6.9 0.7 0.8 1.1 -0.4 -0.7 1.8 -2.6 -0.5 0.8 0.9 -0.1 0.6 -0.2 0.0 -0.7 0.7 0.0 1.1 1.4 0.5 1.1 0.2
Type 2 Diabetes (T2D) (2012) 0.5 0.5 1.7 0.2 -0.6 -0.8 -1.1 -0.7 0.9 -0.2 -0.2 -0.8 -0.9 -0.5 -1.1 -0.8 -0.5 -1.0 -1.3 0.5 0.2 0.1 0.3 -1.1 0.5
Ulcerative Colitis 0.8 1.1 5.3 1.4 0.6 0.8 2.3 1.0 -1.7 0.5 1.3 0.7 0.6 0.2 1.5 1.1 0.8 -0.2 0.7 1.2 -0.6 0.4 1.4 1.3 0.5
Blood Eosinophil Count 0.8 6.0 17.1 2.5 4.0 3.9 0.9 0.8 -1.5 -2.8 1.2 3.1 4.0 1.6 2.8 -0.0 2.0 0.3 2.0 -0.7 2.4 0.9 4.1 2.8 -2.4
Blood Platelet Count 0.3 3.7 10.4 -1.9 -1.9 -2.4 -0.6 -0.1 0.3 -1.3 -2.5 -2.2 -2.1 -1.7 -2.8 -2.9 1.9 2.0 -0.9 -0.1 -1.6 -2.5 -2.1 -3.2 0.3
Blood Red Count 1.0 9.3 33.2 -2.7 -3.6 -4.3 -0.6 0.8 2.3 4.0 -0.6 -3.4 -3.5 -3.9 -2.2 1.3 3.8 5.8 2.2 1.1 0.3 0.9 -4.5 -3.1 3.6
Blood White Count 1.0 7.2 35.3 1.5 1.9 1.6 0.9 2.4 -0.4 -0.5 0.9 2.1 3.6 -0.7 1.3 1.0 5.9 5.9 5.1 -0.8 3.9 2.6 0.9 0.8 -1.0
Heel T-Score 23.7 188.4 1190.2 5.0 9.5 13.0 12.5 3.3 3.5 -1.5 2.4 -4.4 -0.6 5.9 -0.8 -6.7 -23.4 -32.6 -12.9 -7.2 -17.8 -9.7 11.1 -4.5 -34.5
BMI 0.5 3.0 19.0 1.6 1.3 1.6 0.2 -2.2 3.4 -4.4 -2.0 0.0 0.8 -1.9 0.8 -1.2 -0.1 0.6 1.5 0.8 0.2 1.6 0.4 0.0 -2.7
Height 0.8 14.6 52.0 3.0 3.5 4.4 -6.0 -1.7 -2.1 -5.8 -0.2 3.0 2.9 0.7 3.5 3.0 3.4 3.3 3.0 1.4 5.8 7.2 2.1 4.8 4.3
Waist Hip Ratio (WHR) 0.4 1.8 10.3 0.1 -0.6 0.3 0.1 -0.7 -1.8 0.0 0.1 -0.1 -1.4 -1.6 0.2 1.0 1.2 1.8 1.1 3.2 0.2 2.5 -0.5 0.9 2.7
Systolic Blood Pressure 0.5 2.7 11.4 -1.0 -1.9 -1.2 -0.4 1.3 0.9 1.9 0.6 -0.0 -1.3 2.5 -1.4 -0.8 -1.3 -2.3 0.1 3.4 -2.2 -0.8 0.9 -0.5 3.2
Smoking Status 0.7 1.7 9.7 0.7 -0.2 0.1 -0.4 -0.5 -1.9 -3.1 1.5 0.5 0.9 0.1 0.9 -0.1 0.5 0.7 0.6 2.0 -0.4 1.4 0.8 1.9 2.6
Allergy or Eczema 0.7 1.8 7.1 -1.1 -0.4 -0.6 0.5 -0.8 1.6 -2.0 -1.5 -1.1 -0.9 0.8 -1.7 -1.8 -1.8 -1.6 -0.7 -1.1 -0.5 -2.7 -0.1 -1.4 -1.4
Cardiovascular Disease 0.9 3.1 24.7 -0.7 -1.3 -0.8 -0.6 -1.4 1.8 -0.5 1.4 -0.6 -1.9 1.2 0.9 -2.3 -0.9 -2.0 0.9 5.0 -1.7 0.2 1.6 -1.1 3.0
Hypothyroidism (self reported) 0.5 1.2 6.6 -0.1 0.7 0.4 0.0 1.3 0.5 -0.0 1.8 1.2 0.6 2.6 1.4 1.1 1.1 0.2 -0.7 -1.6 0.7 0.0 0.8 1.9 -0.3
Respiratory disease 1.1 2.5 6.7 -1.4 -2.1 -1.9 -0.7 -1.3 0.5 -2.4 -2.6 -1.9 -1.1 -1.2 -1.6 -0.8 1.5 2.5 1.4 0.1 1.1 -0.4 -1.5 -2.5 1.2
Type 2 Diabetes (T2D) (2018) 0.8 1.4 3.0 -1.4 -1.5 -1.2 -1.4 -1.5 1.2 -1.1 -1.3 -1.3 -1.2 -0.7 -1.7 -1.4 0.0 0.9 -0.2 -0.2 -1.1 -0.7 -1.7 -1.6 0.3
Lung FEV1/FVC ratio 1.1 5.8 17.4 3.9 3.5 3.4 0.6 1.5 0.7 0.8 3.2 4.2 2.1 2.3 2.4 3.3 0.6 -0.6 0.1 -0.5 1.2 2.3 2.9 3.8 -0.2
Lung FVC 0.3 1.7 10.8 0.4 0.6 0.2 0.8 3.3 -1.6 3.1 1.1 -0.2 -0.7 -0.8 1.1 2.2 0.1 0.2 0.0 -0.0 -1.4 0.6 -1.1 0.2 -0.6
Neuroticism 0.4 0.9 4.0 -0.1 0.5 0.5 1.6 1.4 0.6 -1.1 0.9 0.2 0.8 0.6 0.4 -1.2 -0.3 -0.2 1.6 0.9 0.2 -0.5 1.0 -0.8 -2.0
Chronotype (morning person) 1.2 2.7 7.6 1.0 1.2 1.1 0.1 2.6 -1.1 2.4 2.5 2.7 1.7 2.1 -0.2 2.4 0.9 0.7 -0.4 -2.8 0.6 -0.4 0.5 1.9 -1.0
Hair Pigment 0.3 9.9 21.0 -4.6 -4.3 -3.5 -3.8 -2.2 -1.7 -0.2 -2.3 -4.3 -4.2 -3.2 -4.2 -3.7 1.4 0.1 -4.2 0.5 -3.5 -2.9 -3.1 -2.7 1.5
Tanning 0.5 6.1 20.6 2.2 2.1 1.9 -0.6 1.4 -3.0 1.3 3.2 3.7 3.4 1.2 2.4 2.7 2.5 2.3 2.3 -0.8 4.5 2.7 1.8 3.2 0.9
Hand grip strength (left) 0.4 1.0 5.3 0.8 0.1 0.9 -0.6 0.1 -0.1 2.3 0.9 0.5 0.4 -0.3 1.7 0.5 0.0 0.4 -0.2 2.2 -1.0 1.5 0.2 1.4 -0.0
Number of treatments/medications taken 0.3 0.6 3.0 1.4 0.6 0.4 0.6 0.3 0.4 0.0 0.8 -0.2 0.2 -0.0 1.2 0.2 -0.2 -0.3 1.4 1.7 -0.1 1.3 1.0 -0.4 0.7
Average weekly spirits intake 0.9 1.1 3.8 1.3 1.1 1.3 0.5 0.0 0.2 -0.4 -0.9 1.2 1.4 -0.5 2.0 0.3 1.1 1.4 1.1 -0.8 1.4 1.7 -0.2 0.8 -1.0
Sensitivity / hurt feelings 2.1 3.7 11.0 1.9 2.4 1.9 2.0 2.2 -0.6 -0.2 2.0 2.2 2.6 1.0 1.9 1.6 1.1 1.5 2.9 0.8 3.3 2.2 2.0 1.6 -0.4
Frequency of depressed mood in last 2 weeks 0.4 0.5 1.9 0.3 0.0 0.5 -0.0 -0.6 -0.6 -0.1 0.8 -0.1 0.0 -1.0 0.7 -1.3 1.4 1.1 0.7 1.0 -0.4 0.9 -0.2 -0.2 -0.9
Hearing difficulty/problems: Yes 5.4 8.2 22.0 4.3 3.9 3.4 0.3 2.5 -1.0 1.1 3.0 4.2 4.7 1.4 2.8 3.8 0.8 -0.3 2.3 -0.7 3.5 3.1 3.6 3.4 0.2
Relative age of first facial hair 0.9 1.8 7.6 -0.9 -0.5 -0.8 -0.9 -1.0 1.4 -0.8 -0.5 -0.4 -0.3 2.5 -0.8 -2.2 -1.7 -2.6 -0.6 -0.3 -0.0 -2.8 1.0 -1.5 0.8
Other serious medical condition/disability diagnosed by doctor 1.1 1.5 11.2 -0.2 -1.2 -1.4 -0.2 0.8 0.1 3.3 1.7 -0.2 -0.8 -1.8 -0.9 1.7 1.1 1.4 -1.1 -0.3 -0.7 -0.7 -0.9 0.5 0.7
Ever used hormone-replacement therapy (HRT) 0.7 0.8 2.7 0.2 0.6 0.6 -1.1 0.6 -1.3 0.2 0.9 1.6 1.6 -1.0 0.3 0.1 0.6 -0.5 0.6 0.9 1.3 0.3 1.5 1.1 0.7
Ever had hysterectomy (womb removed) 2.4 2.8 8.9 -2.1 -1.8 -2.1 -2.2 -0.6 -0.5 0.2 -0.7 -1.9 -1.9 -3.0 -2.0 -1.1 2.4 2.8 -0.4 0.2 -0.4 0.1 -1.9 -1.4 1.4
Systolic blood pressure, automated reading 0.4 1.2 4.6 -0.7 -1.4 -1.1 -0.5 1.3 1.0 0.2 -0.7 -0.8 -1.3 -1.1 -2.1 -0.1 -0.3 -0.8 -0.0 1.8 -1.9 0.2 -0.3 -0.8 1.9
Eye problems/disorders: Diabetes related eye disease 1.4 1.5 4.5 -1.2 -1.2 -1.4 -0.4 -1.6 1.3 1.7 -0.4 -0.6 -1.2 -0.9 -1.6 -0.7 -1.2 -0.7 -1.6 -1.1 -0.6 -2.1 -1.3 -1.6 0.2
Angina 0.9 1.2 8.2 1.2 0.9 0.4 2.9 2.0 1.4 -0.2 1.6 0.8 0.5 0.8 0.7 -0.8 -0.7 0.3 1.5 0.5 1.0 -0.1 0.8 0.1 0.1
Medication for hormone replacement therapy 0.5 0.6 3.6 1.1 0.7 1.0 -0.2 -0.3 -1.9 0.9 0.2 0.2 0.6 -0.9 0.4 0.6 0.0 -0.5 -0.6 0.8 -0.4 0.7 0.8 1.2 0.1
Vitamin and mineral supplements 1.0 1.4 5.4 -0.1 -0.7 -0.5 0.2 0.7 1.1 1.9 1.2 -0.6 -1.0 -1.9 1.3 0.2 1.9 2.3 1.2 1.2 0.1 1.7 -0.8 0.2 0.1
Supplements: Zinc 1.2 1.3 3.8 1.4 1.4 1.7 0.5 0.2 -0.8 -0.4 1.1 1.9 1.1 1.9 1.6 0.8 -0.6 -0.5 0.9 0.5 1.2 1.0 1.4 1.0 0.6
Medication: Co-codamol 0.5 0.6 3.0 -1.0 -0.3 -0.2 -0.2 -1.7 0.5 -1.2 -0.7 -0.7 -0.7 -0.2 -0.2 -1.7 -0.3 0.2 -0.1 0.8 -0.0 -0.1 -0.2 -1.0 -0.5
Medication: Metformin 1.0 1.5 5.3 -1.2 -1.8 -1.7 -0.7 0.1 0.9 -0.0 -0.3 -1.1 -1.3 -1.0 -2.3 -1.3 0.4 0.7 -0.3 -0.8 -0.8 -1.5 -1.8 -2.0 0.9
Diabetes (father) 0.2 0.3 0.8 0.1 0.6 0.9 -0.8 0.2 0.3 0.7 -0.3 0.2 0.3 0.7 0.7 -0.1 -0.4 -0.5 0.2 -0.1 0.6 0.6 -0.2 -0.5 -0.9
Diabetes (mother) 0.6 0.8 3.7 0.0 -1.2 -0.9 1.0 -0.1 0.5 0.0 -1.9 -0.9 -0.6 -0.6 -1.6 0.0 -0.6 0.7 0.3 0.5 -0.3 1.0 -1.4 -1.0 1.2
Severe depression (siblings) 1.0 1.1 5.0 1.1 1.3 1.2 0.7 -0.0 -0.7 -0.1 1.7 1.2 0.4 0.9 1.5 0.4 0.0 -1.4 -0.4 0.2 0.3 0.4 1.9 2.2 -0.3
Pack years adult smoking proportion 0.8 1.2 6.9 1.0 0.0 0.3 0.4 0.5 -1.1 0.5 -0.1 0.0 0.8 -0.6 1.3 1.0 1.2 2.2 1.7 1.0 -0.6 2.6 -1.1 1.1 0.3
Impedance of leg (right) 0.6 2.9 12.3 0.7 -0.0 0.8 -1.5 1.7 -1.8 0.8 -0.3 1.4 0.9 -0.9 -0.1 3.5 2.9 3.3 -0.4 -2.7 1.2 1.1 -1.9 1.8 1.2
Leg fat-free mass (left) 0.6 3.0 13.4 1.3 1.8 1.6 -0.9 -2.8 1.4 -3.7 -0.3 0.6 0.8 1.3 2.2 -0.8 -0.5 -0.1 1.9 2.0 1.9 2.5 2.1 1.6 0.8
Trunk fat percentage 1.1 4.4 23.9 1.4 0.9 0.3 -0.9 -1.0 1.9 -3.6 -1.2 0.5 1.4 -2.6 1.4 0.9 3.5 4.9 2.5 -0.8 2.9 2.8 -1.3 1.4 0.5
Hand grip strength (right) 0.4 1.0 5.4 0.7 0.6 1.2 -0.2 0.2 0.2 1.8 0.9 1.0 0.1 0.3 2.0 0.7 -0.3 0.3 0.5 2.3 -0.1 1.5 0.4 1.2 0.7
Townsend deprivation index at recruitment 1.7 2.4 12.1 -2.2 -1.5 -1.1 -1.2 -3.5 1.0 -2.6 -1.9 -1.4 -1.5 0.4 -1.0 -2.4 -1.3 -0.7 -1.0 1.0 -0.8 -0.9 -1.0 -1.1 0.0
Current tobacco smoking 1.1 1.8 6.3 0.0 -0.8 0.0 -0.0 0.0 -1.7 -1.0 1.8 -0.2 -0.2 -1.2 0.9 0.5 1.5 2.2 0.7 2.3 -1.8 2.5 -1.1 1.9 1.6
Average weekly fortified wine intake 0.4 0.4 2.2 -0.2 -0.5 -0.4 -1.5 -0.4 0.0 1.4 0.8 -0.7 -0.8 -0.3 0.0 0.7 1.0 0.7 -0.4 -0.5 -0.1 0.1 -0.5 0.3 -0.5
Maternal smoking around birth 0.3 0.5 1.7 1.0 -0.4 0.6 -0.4 0.3 -0.6 0.5 -0.0 0.5 -0.4 1.3 -0.2 1.2 -0.0 -0.2 -0.4 1.0 -1.1 -0.2 0.8 0.4 1.1
Fed-up feelings 0.2 0.4 2.1 -0.1 -0.3 -0.3 0.6 0.3 0.0 -0.5 0.4 -0.5 -0.2 -0.3 0.5 -0.9 0.8 0.8 0.5 1.4 -1.0 1.0 -0.5 0.3 0.0
Frequency of unenthusiasm / disinterest in last 2 weeks 1.1 1.5 7.2 1.7 0.6 0.7 0.2 0.5 0.8 1.3 1.5 0.3 0.8 -1.3 1.0 -0.0 1.8 1.7 2.7 1.6 0.8 1.7 0.6 0.4 0.2
Relative age voice broke 1.7 2.6 5.9 -1.5 -1.7 -1.9 -2.4 -2.1 0.9 -1.0 -1.5 -1.8 -1.7 0.4 -2.1 -2.1 -1.6 -1.3 -1.2 -0.4 -1.1 -2.2 -1.0 -1.9 1.4
Taking other prescription medications 0.3 0.4 2.0 0.5 -0.7 -0.7 0.0 0.6 1.4 1.0 0.2 -0.5 -0.0 0.0 0.4 0.8 1.2 1.4 0.4 -0.2 0.3 0.2 -0.4 -0.5 0.5
Age when periods started (menarche) 1.1 2.5 7.4 -2.1 -1.1 -1.4 -2.4 -0.8 -1.6 2.2 0.2 -0.8 -1.3 0.3 -1.4 -0.3 -0.8 -1.4 -2.7 -2.7 -0.3 -2.6 -1.4 -1.9 0.0
Bilateral oophorectomy (both ovaries removed) 0.6 0.6 3.5 -0.6 -0.9 -0.4 -1.0 -0.7 0.6 -0.8 -0.1 -0.5 -0.7 -1.7 -1.2 -1.1 0.2 -0.2 0.4 1.9 0.1 -0.2 0.3 -0.3 0.5
Heel bone mineral density (BMD) T-score, automated (left) 12.3 27.9 169.0 1.8 3.9 4.8 5.0 1.4 1.1 -0.2 0.9 -2.0 -0.8 2.1 -0.1 -2.2 -8.5 -12.6 -5.4 -3.0 -7.4 -4.1 4.3 -0.9 -13.0
Tinnitus: Yes, but not now, but have in the past 1.9 2.0 7.1 -2.2 -1.0 -1.3 -0.1 -0.5 0.3 -0.2 -1.4 -1.7 -0.3 -1.9 -1.3 -1.1 0.9 2.0 -0.3 -1.8 -0.5 -0.8 -2.0 -2.7 -2.0
Qualifications: CSEs or equivalent 1.2 1.5 4.1 1.0 1.3 1.4 1.8 2.0 0.8 0.8 1.6 1.5 1.2 2.0 0.3 0.8 -0.7 -1.0 0.8 -0.8 0.8 -0.9 1.9 1.2 -0.4
Serious illness, injury or assault to yourself 1.9 2.3 19.8 0.2 -1.4 -1.1 -1.7 -1.0 -0.9 1.9 0.5 -0.1 -1.1 -2.0 -0.5 0.6 1.4 1.9 0.7 1.6 0.4 1.7 -1.2 -0.7 4.4
High blood pressure 1.1 3.2 17.0 -1.4 -2.1 -2.1 -0.6 -1.6 0.4 -0.3 0.8 -1.9 -2.7 -1.4 -0.8 -1.6 -0.1 -0.7 -0.6 4.1 -3.4 0.2 -0.6 -1.4 2.8
Hayfever, allergic rhinitis or eczema 0.6 1.3 3.7 -0.2 -0.2 -0.0 0.5 -0.7 1.7 -1.8 -1.4 -0.5 -0.3 1.1 -1.1 -1.9 -1.8 -1.9 -0.4 -0.6 -0.4 -1.8 0.6 -0.8 -1.4
Multivitamins +/- minerals 1.2 1.6 4.2 -0.3 -0.1 0.2 -1.3 -1.3 -1.1 -2.0 -1.2 -0.3 0.1 1.2 -2.1 -0.7 -1.3 -2.0 -2.0 -1.7 -0.8 -1.8 -0.1 -0.6 -0.8
Stomach or abdominal pain in last month 0.7 0.9 3.6 -0.8 0.3 0.4 -0.1 -1.0 -1.8 -0.8 1.5 1.2 1.2 0.7 -0.1 0.2 0.0 -1.3 -1.2 -1.9 0.8 -0.8 0.6 0.2 -0.5
Supplements: Glucosamine 0.3 0.4 1.5 0.6 0.5 0.4 -0.1 0.3 -0.5 1.1 0.3 0.7 0.9 -0.9 -0.8 0.0 -0.4 -1.1 -0.2 -0.7 1.2 -0.4 0.7 0.2 -0.5
Diverticular disease/diverticulitis (self-reported) 0.7 0.9 3.5 -0.9 -1.1 -0.7 -0.8 -0.6 0.5 -1.8 -0.3 -0.2 -0.7 -0.0 -1.2 -1.2 -1.0 -0.8 -1.4 -1.0 -0.8 -1.9 -0.2 -0.0 -0.5
Medication: Atenolol 1.2 1.5 5.2 0.6 1.0 1.2 1.2 -0.6 0.2 -0.9 1.9 0.7 0.4 0.8 2.3 -1.1 -0.6 -1.2 1.4 1.9 0.3 1.8 1.9 1.2 0.3
Medication: Levothyroxine sodium 0.5 0.8 2.5 0.1 0.5 0.3 -1.3 1.2 0.5 0.0 1.1 1.3 1.0 1.5 0.5 0.7 1.0 0.3 -0.8 -1.3 0.6 -0.1 0.8 1.6 -0.1
Sitting height 0.8 5.4 25.2 2.6 2.9 3.7 -2.5 -2.3 -1.9 -3.4 -0.7 1.2 1.9 0.1 2.6 0.9 0.7 1.2 2.4 1.3 2.3 5.0 1.7 2.7 -0.5
Chronic bronchitis/emphysema (father) 0.4 0.4 1.8 -0.7 -1.2 -0.9 -0.2 0.4 0.4 1.4 0.5 -0.2 -1.0 -0.1 -0.2 0.5 0.3 0.5 -0.3 -0.9 -0.3 -0.5 -1.2 -0.1 0.5
High blood pressure (mother) 0.9 1.3 6.1 -0.2 -0.9 -0.2 -0.7 -1.6 2.5 -0.9 0.7 -1.4 -2.0 -0.0 -1.3 -1.0 -1.3 -1.4 -0.9 0.7 -1.0 0.3 -0.3 -0.8 -1.6
Body mass index (BMI) 0.4 1.7 9.8 1.4 1.2 0.8 0.7 -1.6 2.7 -3.1 -0.6 0.0 0.6 -1.3 1.3 -0.7 0.3 0.9 1.2 1.0 0.2 1.6 0.4 0.8 -1.2
Impedance of leg (left) 0.6 2.7 10.5 0.9 0.1 1.0 -1.3 1.6 -2.1 0.9 -0.4 1.4 1.0 -1.1 0.0 3.2 3.2 3.2 -0.0 -2.5 1.1 1.0 -1.8 1.5 0.5
Leg predicted mass (left) 0.5 2.8 13.0 1.2 1.7 1.5 -1.0 -2.8 1.4 -3.6 -0.2 0.5 0.7 1.2 2.1 -0.8 -0.5 -0.1 1.9 2.0 1.8 2.4 2.0 1.5 0.9
Trunk fat mass 1.0 4.3 19.1 1.8 1.4 1.1 -1.2 -1.9 1.9 -4.4 -1.3 0.6 1.4 -1.9 1.8 0.6 2.8 3.9 2.4 -0.2 2.9 3.1 -0.4 1.8 0.2
Waist circumference 0.8 2.9 13.9 2.0 1.7 1.4 0.2 -1.9 1.4 -3.7 -0.5 0.8 1.1 -1.8 1.6 0.3 1.5 2.0 2.1 1.4 1.6 3.1 0.8 1.6 0.4
Number of incorrect matches in round 3.6 5.9 16.2 2.4 2.4 1.2 4.0 3.8 -2.5 2.0 3.8 2.0 1.9 0.9 3.2 2.1 0.6 0.7 2.7 2.3 1.3 3.0 2.6 2.1 1.8
Past tobacco smoking 0.9 1.7 15.0 -0.3 -0.6 -0.3 0.9 1.5 2.0 3.9 -0.1 -0.9 -1.1 -1.3 0.5 0.7 -0.2 1.1 1.5 1.0 -0.2 1.5 -1.4 -0.4 -1.1
Alcohol usually taken with meals 0.5 0.9 4.3 0.6 -0.0 0.4 -1.3 1.0 -1.1 2.1 0.7 0.5 0.4 -1.0 -0.6 -0.4 0.6 0.5 1.6 -0.2 1.8 0.4 0.1 -0.9 -0.6
Nervous feelings 0.4 0.8 3.9 -0.7 -0.7 -0.3 -0.6 -1.0 -0.6 -2.0 -0.3 -1.1 -0.7 -1.8 -0.9 -1.0 0.8 0.7 0.4 -0.0 0.2 0.1 -0.4 -0.9 -1.3
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.3 1.6 -0.4 -0.5 -0.1 0.1 -0.5 -0.6 0.3 -0.3 -0.2 0.5 0.6 -0.3 -1.0 0.9 0.5 -0.0 -0.4 -1.3 -0.7 -0.6 -0.1 -1.0
Hearing difficulty/problems with background noise 1.8 2.9 8.8 3.0 2.9 2.5 0.9 1.3 -0.5 0.4 1.9 1.9 2.0 0.2 1.7 2.4 -0.3 -1.0 1.2 -0.8 1.7 1.5 2.2 1.7 -1.4
Hair/balding pattern: Pattern 2 3.6 4.6 10.9 -2.8 -3.3 -3.3 -0.8 -2.0 0.5 -0.0 -1.2 -2.2 -3.2 -1.8 -1.8 -2.6 1.5 0.7 -2.7 1.1 -2.4 -2.5 -2.5 -1.5 2.6
Had menopause 0.6 0.7 5.4 -0.5 -0.2 0.0 -1.3 -0.1 -0.8 -1.2 -0.4 0.5 1.2 -2.3 -0.3 -1.0 1.2 0.5 -0.1 -0.3 1.3 -0.3 -0.0 0.1 -0.5
Had other major operations 0.6 0.8 2.5 -0.3 0.1 -0.4 -1.6 -0.3 -1.5 -0.9 -0.3 -0.8 -0.9 -1.0 -0.6 1.1 1.4 0.9 -0.8 0.4 -1.0 0.9 -0.7 0.2 1.1
Forced vital capacity (FVC) 0.6 2.4 7.5 1.5 1.7 2.0 -2.4 0.3 -1.7 -0.4 0.3 1.6 0.9 1.3 2.0 2.2 0.4 0.2 1.3 1.3 1.2 2.7 0.9 2.2 1.5
Heel bone mineral density (BMD) T-score, automated (right) 13.3 30.6 204.5 2.4 4.5 6.0 4.8 2.0 1.1 -1.1 1.1 -1.6 -0.0 2.5 0.1 -2.2 -8.5 -12.8 -5.1 -3.5 -7.3 -3.4 4.7 -0.2 -14.3
Ever unenthusiastic/disinterested for a whole week 0.7 0.8 3.4 -0.3 -0.1 -0.5 1.9 1.1 1.0 1.7 1.4 0.1 -0.2 1.2 0.5 -0.3 -0.8 -0.8 -0.1 0.3 -0.4 -1.3 0.4 -0.5 -1.0
Qualifications: None of the above 0.3 0.7 2.6 -0.2 -0.4 -0.5 -0.8 -0.1 -0.6 -0.8 -0.4 -0.9 -0.6 -1.1 -0.2 0.2 1.1 1.6 1.3 1.1 0.2 1.2 -0.3 -0.9 1.5
Financial difficulties in last 2 years 0.5 0.7 3.4 -0.2 -1.0 -0.1 -1.8 -1.2 0.0 -1.4 0.1 -0.7 -0.6 0.5 -0.1 -1.7 -0.5 0.4 0.3 0.7 -0.2 0.3 -0.8 0.1 1.0
Mouth/teeth dental problems 0.5 0.8 5.4 -0.7 -0.6 0.1 -1.1 0.5 0.7 -0.4 -0.9 -1.2 -0.4 -2.3 -0.9 -0.5 0.0 0.6 0.3 -0.5 -0.8 0.1 -0.5 -0.7 -1.8
Heart attack 1.0 1.3 4.9 -1.8 -0.8 -1.6 0.2 -0.3 -0.1 -0.1 -1.2 -1.1 -0.3 -0.5 -1.0 -1.2 -0.9 0.4 -0.6 -1.9 0.7 -1.6 -1.9 -2.2 0.5
Allergy 0.4 0.9 3.4 0.3 0.8 0.5 0.3 1.2 -1.8 1.9 1.3 1.0 0.3 0.1 1.0 1.6 0.7 0.2 -0.7 0.2 -0.7 0.7 -0.3 1.5 0.7
Pain all over the body in last month 0.4 0.4 2.3 -0.6 -0.3 -0.1 -0.8 -1.5 -0.4 0.8 -0.2 -0.2 -1.3 0.4 -0.2 -0.3 -0.1 -0.2 -0.9 0.7 -1.2 -0.2 -0.5 0.5 0.2
Diabetes (self-reported) 1.0 1.5 5.3 -1.1 -1.7 -1.7 -1.4 -0.7 0.3 -0.8 -0.8 -1.8 -1.4 -1.5 -2.3 -0.7 0.7 0.8 -0.0 -0.2 -0.6 -0.7 -1.6 -1.9 0.4
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 2.2 0.2 0.3 0.1 0.0 0.9 0.0 0.1 -0.7 -0.1 -0.0 -0.6 -0.4 0.5 1.3 1.2 1.5 -0.5 0.6 0.4 -0.2 -0.5 -1.1
Medication: Ramipril 0.8 1.0 5.3 -0.1 -0.9 -0.9 -0.6 0.0 -1.6 0.1 -0.1 -0.3 -0.2 -2.3 -0.8 0.9 0.9 1.2 -0.5 -0.6 0.0 0.2 -1.9 -0.9 2.0
Medication: Simvastatin 0.8 1.1 10.0 -0.7 -1.1 -1.1 0.1 0.3 -1.7 0.0 -0.4 -0.3 0.1 -0.2 -0.3 -0.2 0.7 1.0 1.9 1.1 0.5 1.2 -0.8 -0.4 3.2
Fluid intelligence score 0.5 1.0 6.5 -0.9 -0.5 -0.3 -1.7 -1.2 0.6 -2.5 -1.2 -0.6 -0.7 -0.7 0.5 -1.1 0.8 0.7 0.9 1.9 0.3 0.7 0.1 0.3 -0.2
Illnesses of siblings 1.8 2.6 8.4 1.8 1.9 1.8 0.4 1.8 -0.5 0.2 0.9 2.4 2.9 2.3 1.2 2.5 0.5 -0.1 1.4 -1.1 1.7 1.4 1.7 1.8 -0.2
Neuroticism score 0.3 0.6 2.1 0.2 0.5 0.6 1.4 0.4 -0.1 -1.2 1.1 0.1 0.5 0.4 0.7 -0.9 -0.1 -0.2 1.1 1.3 -0.4 0.1 0.9 -0.2 -1.2
Weight 0.8 4.1 23.5 2.1 2.1 2.1 -1.3 -2.8 2.3 -4.8 -0.9 0.9 1.3 -0.4 2.5 -0.4 0.8 1.5 1.9 1.5 2.0 3.4 1.2 2.1 0.0
Impedance of arm (right) 0.6 2.8 16.9 -0.4 -0.3 -0.9 -1.1 1.6 -0.7 0.4 -0.0 0.7 0.9 0.1 -0.2 1.9 3.3 4.1 0.8 -3.0 2.8 -0.0 -1.7 0.2 1.9
Arm fat percentage (right) 0.6 2.4 12.3 1.1 0.8 -0.2 0.1 -1.1 2.9 -3.3 -1.0 -0.2 0.6 -2.0 0.4 0.3 2.3 3.5 1.6 -0.9 1.3 1.3 -0.9 0.8 -0.2
Trunk fat-free mass 0.5 2.8 11.3 1.2 1.7 2.0 -1.5 -2.8 1.0 -3.4 -0.5 0.5 -0.0 1.6 1.6 -0.6 -1.6 -1.4 0.5 2.5 0.4 2.2 2.1 1.9 0.7
Hip circumference 0.7 3.1 14.7 2.2 2.3 1.6 -0.9 -1.9 2.3 -3.8 -0.4 1.3 1.9 -0.0 2.2 -0.1 0.9 1.1 1.6 0.2 2.0 2.6 1.2 1.7 0.3
Time employed in main current job 0.4 0.5 2.3 -0.4 -0.3 -0.6 -1.5 0.4 -0.6 -0.6 -0.8 -0.2 -1.0 0.2 -1.4 0.5 -0.3 0.1 -0.8 0.6 -0.8 -0.1 -0.1 -0.7 1.2
Alcohol intake versus 10 years previously 0.5 0.8 2.0 -0.4 -1.1 -1.0 -1.0 -0.8 1.1 -1.4 -0.8 -1.2 -0.6 -0.7 -1.0 -0.2 1.0 1.3 -0.3 0.3 -0.9 0.5 -1.3 -0.1 0.1
Father’s age at death 1.0 1.4 7.4 -1.1 -1.2 -1.2 -2.0 -0.2 0.0 -1.3 -1.7 -0.7 0.1 -0.0 -1.6 0.1 1.0 0.2 -1.3 -2.7 -0.1 -0.9 -1.8 -0.6 0.0
Worrier / anxious feelings 1.8 3.5 12.6 2.3 2.4 2.2 3.6 2.8 0.6 -0.5 1.3 1.6 1.8 1.7 1.4 1.1 -1.4 -1.6 2.6 2.0 0.5 0.8 3.0 0.5 -0.8
Frequency of tiredness / lethargy in last 2 weeks 0.6 0.9 5.1 0.9 -0.3 0.4 -0.2 -0.1 -0.3 1.4 1.2 0.7 0.8 0.0 0.7 0.2 2.0 2.2 1.1 1.0 -0.4 1.0 -0.1 1.1 0.3
Falls in the last year 0.5 0.7 1.9 1.1 0.5 0.9 -1.3 -1.1 0.0 -0.7 0.3 0.9 1.3 0.1 0.1 0.3 0.5 0.6 0.1 -1.4 1.3 1.2 -0.4 0.9 -0.0
Hair/balding pattern: Pattern 3 1.7 2.6 8.2 1.4 2.0 1.8 1.7 0.8 1.4 0.6 1.3 1.6 1.1 2.2 1.6 -0.7 -2.6 -2.9 1.1 0.6 1.5 -0.1 2.9 0.1 -1.4
Number of live births 3.5 5.0 11.4 -3.0 -2.5 -2.2 -3.4 -2.9 0.6 -1.4 -2.7 -2.9 -2.9 -2.5 -2.6 -2.9 -0.3 -0.8 -1.9 0.3 -1.2 -1.6 -1.9 -3.0 1.1
Forced expiratory volume in 1-second (FEV1) 1.1 3.8 11.0 2.6 2.5 2.7 -1.5 0.6 -1.2 -0.2 1.0 2.6 1.2 1.8 2.6 3.3 1.0 0.7 1.5 1.0 1.6 3.3 1.5 2.8 1.4
Pulse rate 1.5 2.5 7.0 2.0 0.9 1.5 1.1 2.2 1.1 2.4 2.1 1.3 0.5 0.7 2.6 2.5 -0.4 -0.3 0.7 2.1 -1.0 1.5 1.0 2.0 0.8
Happiness 0.4 0.5 2.4 -1.2 -0.9 -0.8 0.3 0.7 -0.1 1.5 0.3 -0.1 -1.2 -0.0 -1.3 -0.3 -0.5 0.4 -0.5 -0.2 -0.6 -0.6 -0.5 0.2 -0.2
Noisy workplace 0.4 0.5 1.6 0.2 -0.4 -0.8 0.7 0.3 0.6 0.9 0.2 -0.5 -1.3 -0.7 -0.5 -0.5 -1.0 -0.2 -0.7 1.2 -0.7 -0.2 0.1 0.1 1.2
Qualifications: A levels/AS levels or equivalent 0.4 0.9 4.7 -0.5 -0.0 -0.4 0.2 -0.5 0.4 0.4 -0.1 0.6 -0.6 2.2 -0.3 0.3 -0.2 -1.0 -2.1 -2.1 -0.2 -1.7 -0.4 0.3 0.5
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.8 2.9 1.2 0.4 0.3 -0.3 1.0 -1.6 1.7 1.3 0.7 0.3 0.7 0.8 0.2 0.7 -0.4 0.3 1.2 -0.5 0.5 0.5 0.2 1.7
Mouth/teeth dental problems: Dentures 1.4 2.4 7.0 -1.9 -2.6 -2.1 -1.2 -1.1 1.8 -0.8 -1.4 -1.7 -1.7 -0.4 -2.0 -1.5 -0.3 0.1 -1.2 -0.3 -0.7 -1.6 -2.0 -1.4 2.3
Asthma 1.3 2.5 6.8 -2.1 -2.6 -2.2 -1.3 -1.7 1.2 -1.7 -1.6 -2.0 -1.3 -1.1 -1.6 -1.3 1.0 2.0 0.6 -0.2 0.9 -0.5 -1.5 -2.5 1.0
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.7 -0.2 -1.1 -0.2 -1.3 -1.2 -0.4 0.4 -0.2 -0.0 -0.7 1.1 -0.2 -1.2 -1.1 -0.8 -1.0 0.6 -0.4 -0.5 -0.3 -0.3 0.3
Medication: Cholesterol lowering 0.6 0.9 5.6 -1.1 -1.3 -1.8 -0.1 -0.7 -0.7 -0.7 -1.0 -0.8 -0.9 0.2 -1.1 -0.4 -0.4 0.1 0.0 -0.1 0.1 -0.8 -0.9 -1.3 2.4
Depression (self-reported) 0.8 0.9 4.6 1.1 -0.3 0.1 0.8 0.1 -1.3 0.8 -0.3 -0.6 0.0 -1.4 0.8 0.0 0.2 1.2 2.1 1.4 0.4 1.7 -0.9 0.1 1.0
Medication: Lansoprazole 1.0 1.1 6.0 -0.2 -1.0 -1.0 -0.7 -0.5 0.0 1.0 -0.0 -1.3 -1.0 -2.0 -0.2 -0.5 0.5 0.7 1.1 2.4 -0.2 0.7 -0.6 -0.8 2.0
Prospective memory result 1.0 1.2 3.5 -0.5 -1.6 -1.2 1.0 -0.8 0.6 -1.2 -0.2 -1.4 -1.8 1.0 -0.4 -1.2 -1.2 -0.1 0.2 1.6 -1.1 -1.2 -0.0 -1.3 1.9
Lung cancer (father) 0.9 1.0 3.6 0.1 -0.2 0.1 -0.3 -0.1 -0.8 -0.5 0.7 0.5 0.8 -1.9 1.7 0.2 1.9 1.7 0.8 0.9 1.2 1.6 0.1 0.6 0.5
Illnesses of mother 0.5 0.6 4.3 -0.4 -0.3 -1.1 0.5 1.2 0.2 0.9 1.2 0.0 -0.4 -0.4 0.2 0.8 0.8 0.3 -0.4 -0.4 -0.3 -0.7 -0.0 -0.7 2.1
Forced expiratory volume in 1-second (FEV1), Best measure 1.6 5.2 17.1 3.3 3.4 3.2 -1.0 1.4 -0.8 0.1 1.2 3.0 2.1 2.5 2.7 4.1 0.9 0.5 1.6 -0.0 2.0 3.1 1.8 3.3 0.3
Pulse wave Arterial Stiffness index 1.1 1.3 4.8 -0.8 -1.0 -0.6 1.0 -0.4 0.7 -1.9 -1.2 -1.9 -1.5 -1.3 -0.0 -1.4 -0.0 1.0 1.2 2.2 -0.9 0.2 -0.3 -1.1 -0.4
Impedance of arm (left) 0.8 3.5 18.7 -0.7 -0.7 -1.3 -1.4 1.1 -1.4 0.6 0.2 0.8 0.9 -0.2 -0.1 1.5 3.6 4.3 1.2 -3.1 3.5 -0.1 -1.9 -0.1 2.5
Arm fat mass (right) 0.6 2.6 14.7 1.8 1.5 1.0 -0.3 -1.8 2.5 -3.8 -0.8 0.3 0.9 -1.3 1.6 0.1 1.5 2.3 1.6 0.5 1.2 2.3 0.2 1.7 -0.2
Trunk predicted mass 0.5 2.8 11.3 1.2 1.6 2.0 -1.5 -2.8 1.0 -3.4 -0.6 0.5 -0.1 1.6 1.6 -0.6 -1.6 -1.5 0.5 2.5 0.3 2.2 2.0 1.9 0.8
Standing height 0.6 5.8 19.6 1.5 2.0 2.8 -4.4 -2.8 -0.5 -3.9 -0.6 2.0 1.4 1.9 2.4 0.7 1.1 1.4 1.2 1.1 3.6 3.8 1.6 3.0 2.8
Length of working week for main job 0.9 0.9 3.2 -1.0 -1.3 -0.8 0.9 -1.1 1.6 -0.1 -0.8 -1.0 -1.0 0.5 -0.4 -0.9 -0.5 -0.1 -0.6 -0.2 -1.1 -1.5 -1.2 -1.8 0.6
Exposure to tobacco smoke at home 0.6 0.7 3.3 -0.8 -0.8 -0.7 -0.6 -1.8 1.7 0.5 -0.1 -0.3 -0.5 -0.4 0.4 -0.4 0.4 1.2 -1.4 -0.7 -0.2 -0.1 -1.4 0.5 0.4
Breastfed as a baby 1.2 1.5 4.8 -1.9 -1.4 -1.7 -1.5 -0.9 -0.2 0.1 -0.4 -0.8 -1.6 -1.3 -1.4 -0.3 -1.0 -0.0 -1.6 -0.8 -0.6 -0.9 -1.8 -1.1 2.2
Tense / ‘highly strung’ 1.2 2.0 12.5 0.4 0.8 1.4 2.0 0.6 -0.6 -1.9 0.2 0.8 2.2 1.2 1.5 -0.9 -1.7 -1.5 1.2 -0.6 0.8 -0.4 1.2 -0.5 -3.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 0.9 5.0 0.6 0.6 0.5 2.2 1.1 0.4 -0.6 2.0 0.9 0.7 0.8 1.0 0.1 -0.4 0.0 0.9 -0.8 1.1 -0.4 0.6 0.3 -1.4
Hair/balding pattern: Pattern 4 1.0 2.5 10.8 2.1 2.5 2.9 1.0 0.5 -0.3 -0.5 0.7 1.3 2.2 -0.2 0.9 1.4 -2.1 -1.8 0.8 -1.3 0.7 1.2 1.5 0.5 -3.3
Birth weight of first child 2.4 4.3 12.9 -2.7 -2.7 -3.0 -1.2 -0.6 2.5 1.9 -0.8 -1.6 -3.0 0.5 -1.8 -1.6 -0.9 -0.4 -3.2 -1.4 -1.8 -3.6 -2.8 -2.2 0.3
Peak expiratory flow (PEF) 0.5 1.3 5.0 0.8 0.2 0.6 -1.9 -1.3 -0.8 -0.2 0.0 0.9 -0.2 -0.0 1.2 1.4 1.5 1.3 0.4 1.2 1.0 1.9 0.1 1.1 2.2
Pulse wave reflection index 1.5 1.9 5.8 -1.7 -1.6 -0.7 -0.5 -0.9 0.3 -1.0 -2.4 -2.1 -1.8 -0.9 -1.7 -2.4 -0.3 0.5 -1.1 0.4 -1.4 -0.7 -1.1 -1.6 -1.5
Ever highly irritable/argumentative for 2 days 0.6 0.7 4.6 0.1 0.2 0.1 0.9 1.1 1.4 1.5 1.1 0.0 -0.0 -0.9 0.1 -0.6 -0.0 1.1 0.3 -0.8 -0.7 -0.5 -0.3 0.1 -2.1
Loud music exposure frequency 1.4 1.5 6.2 1.0 1.3 1.3 -1.3 -2.1 0.5 -1.9 -1.1 1.6 0.8 2.5 0.9 0.2 0.2 -0.9 -1.5 -0.5 -0.7 0.1 0.9 1.7 0.1
Qualifications: O levels/GCSEs or equivalent 0.9 1.5 9.0 -0.2 -0.2 0.1 0.4 -1.6 1.4 -0.3 0.7 -0.4 -0.7 0.5 -0.4 -1.6 -1.7 -3.0 -1.9 -1.4 -0.8 -2.2 0.5 0.1 -0.9
Mouth/teeth dental problems: Bleeding gums 0.7 1.0 2.6 0.2 0.6 -0.1 0.1 -1.3 -1.0 1.6 1.4 1.6 0.9 0.8 1.6 1.4 0.9 1.0 -0.6 0.4 1.0 0.4 0.1 1.0 0.8
Blood clot in the leg (DVT) 1.3 1.7 5.5 1.4 1.5 2.0 -0.5 -1.0 0.2 -1.2 1.3 1.4 1.9 1.4 2.3 -0.9 -0.2 -0.1 1.9 0.5 1.8 1.6 1.5 -0.2 -0.3
Medication: Paracetamol 0.6 0.9 6.5 0.2 0.5 0.6 -0.1 -1.3 1.5 -2.5 -0.9 0.6 1.0 0.5 1.0 -1.3 0.3 -0.1 0.2 0.3 1.1 -0.1 0.9 0.0 -1.2
Headache pain in last month 0.7 1.2 5.4 -0.3 -1.1 -0.6 0.1 -1.0 1.6 -1.3 -0.6 -1.1 -0.6 -0.0 -0.3 -2.3 -1.5 -1.5 -0.7 0.5 -1.2 -1.4 0.3 -1.4 -1.1
Medication for cholesterol, blood pressure or diabetes 0.5 0.9 7.4 0.5 1.0 1.4 0.1 0.5 0.7 0.2 -0.6 0.7 1.4 -0.2 -0.1 0.2 0.6 1.1 0.8 -1.5 1.1 0.1 0.0 0.2 -2.7
Glaucoma (self-reported) 0.8 1.0 4.1 0.1 -0.4 -0.8 0.5 0.7 -0.4 1.7 0.6 -0.8 -0.7 -2.0 0.2 1.4 1.1 2.0 0.1 -0.5 -0.9 0.7 -1.6 -0.2 0.1
Gout (self-reported) 0.5 0.6 3.1 -0.4 -0.5 -0.1 -0.7 -1.4 0.2 -0.1 -0.2 -0.7 -1.2 0.6 -0.4 -0.5 -0.8 -0.3 -1.5 -0.3 -1.8 -0.5 -0.4 0.4 -0.9
Hypothyroidism/myxoedema (self-reported) 1.0 1.9 5.0 0.7 1.5 1.0 -0.2 1.6 -0.4 0.1 1.9 2.0 1.9 2.2 1.5 1.2 1.7 0.2 -0.3 -2.0 1.3 0.2 1.5 2.2 -0.7
Medication: Amlodipine 1.1 1.5 9.7 -0.3 -0.8 -0.7 -0.3 0.2 1.5 -0.1 1.9 -0.7 -1.5 0.9 0.6 -0.5 -0.8 -1.3 0.4 3.1 -1.6 0.1 0.8 -0.5 2.4
Medication: Ventolin 100micrograms inhaler 0.5 0.7 2.2 0.1 -0.7 -0.6 -0.3 0.1 0.1 1.1 -0.6 -0.2 0.4 -1.5 -1.2 1.1 1.3 1.2 0.7 -1.0 0.9 0.0 -0.9 -0.4 0.9
Birth weight 1.1 2.3 7.3 -2.7 -1.1 -1.7 -1.3 -2.6 0.8 -1.4 -2.5 -1.9 -2.0 0.4 -0.9 -1.8 -0.6 0.6 -1.4 -0.6 -0.6 -1.2 -1.9 -1.3 -0.2
Chronic bronchitis/emphysema (mother) 0.7 0.8 3.6 -1.0 0.1 0.1 -0.5 0.3 0.7 1.0 0.1 1.3 0.9 1.1 -0.2 -1.1 0.2 0.8 -1.1 -1.9 0.8 -1.1 -1.0 0.6 -0.9
High blood pressure (siblings) 3.6 5.3 16.8 -2.2 -3.2 -2.6 -1.3 -2.8 1.2 -0.2 -0.6 -3.5 -4.1 -2.6 -2.0 -2.3 -1.4 -0.7 -2.6 1.6 -3.5 -1.3 -2.4 -2.4 0.6
Forced vital capacity (FVC), Best measure 0.9 3.1 8.8 2.2 2.4 2.5 -1.9 1.0 -1.5 -0.1 0.5 2.0 1.4 2.2 2.1 3.0 0.5 0.3 1.5 0.4 1.6 2.8 1.0 2.5 0.7
Body fat percentage 1.0 4.0 19.5 1.8 1.2 0.6 -0.4 -0.9 2.2 -3.4 -1.2 0.6 1.5 -2.3 1.3 1.2 3.2 4.4 2.2 -1.1 2.5 2.6 -1.1 1.5 -0.1
Leg fat percentage (right) 0.8 3.0 10.7 2.0 1.1 1.1 -0.0 -0.5 2.4 -3.1 -0.8 0.6 1.0 -2.4 1.0 1.7 2.5 3.3 1.5 -0.6 1.2 2.6 -0.6 1.8 -0.3
Arm fat-free mass (right) 0.6 3.3 10.2 1.9 2.0 2.7 -1.3 -2.8 0.5 -3.2 -0.3 1.2 0.9 0.9 2.2 -0.4 -1.2 -1.3 1.1 2.4 1.2 2.9 2.3 2.4 0.2
Exposure to tobacco smoke outside home 1.0 1.4 6.4 -1.2 -1.2 -0.9 -2.2 -2.5 -0.5 -2.4 -0.6 -0.3 -0.6 -0.0 -0.7 -0.5 1.1 1.6 -0.4 -0.7 0.6 0.7 -1.6 -0.4 0.3
Comparative body size at age 10 0.9 2.6 16.3 -0.3 1.8 1.4 1.2 -2.9 0.0 -2.3 -0.1 0.1 0.6 0.7 0.9 -2.5 -1.1 -2.1 -1.4 -1.8 -0.4 -0.8 1.0 -0.1 -4.0
Number of full brothers 1.3 1.7 8.2 -0.8 -0.6 -0.2 -1.5 -1.2 1.6 -2.6 -1.5 -0.9 -0.1 -1.0 -0.4 -1.7 2.1 2.9 0.9 -0.4 0.6 -0.0 -0.9 -0.7 -0.7
Worry too long after embarrassment 0.3 0.6 2.2 0.0 -0.5 -0.8 0.4 0.9 0.6 1.0 0.7 -0.2 -0.3 -1.2 0.4 0.3 0.7 1.2 0.4 0.8 -1.2 -0.1 -0.4 -0.4 1.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 2.7 -0.2 -0.9 -0.5 1.6 -0.1 -0.6 -0.4 1.2 -0.3 -0.0 -0.2 -0.2 -1.7 -0.8 -0.1 0.6 -0.4 -0.1 -1.1 -0.3 -0.7 -1.2
Wheeze or whistling in the chest in last year 0.8 1.4 4.4 0.0 -1.2 -0.4 -1.9 -1.3 1.7 -1.7 -1.8 0.0 1.3 0.4 -0.3 -1.0 2.1 2.1 0.6 0.6 0.0 0.8 -0.5 0.0 1.1
Number of children fathered 0.5 0.6 3.0 0.7 0.6 0.1 0.8 -0.2 0.6 0.3 0.5 -0.2 -0.5 1.3 0.3 1.3 -0.4 -1.7 -1.4 -0.3 -1.2 -0.4 0.6 -0.1 0.4
Reason for reducing amount of alcohol drunk: Health precaution 1.2 1.4 4.8 1.9 0.8 1.2 -0.0 2.2 -1.3 1.3 1.4 1.3 0.9 -0.5 0.8 1.7 -0.5 -1.2 0.5 0.9 -0.5 1.3 1.3 0.9 0.5
Age at first live birth 0.3 0.5 2.2 0.4 0.4 -0.3 0.4 0.6 -0.6 0.1 -0.6 -1.5 -1.0 -0.7 -0.6 0.4 -0.4 -0.9 -0.1 -0.9 -1.0 -0.3 -0.3 -0.9 -1.0
Pulse wave peak to peak time 1.2 1.4 4.7 1.0 1.1 0.9 -1.2 0.4 -0.7 1.8 1.3 2.2 1.7 1.3 0.3 1.5 0.1 -0.8 -0.8 -2.0 1.4 0.2 0.5 1.3 0.7
Health satisfaction 0.3 0.4 3.4 -0.6 -0.4 -0.4 -0.8 -0.4 -0.7 1.8 0.3 -0.1 -0.9 -0.9 -0.1 -0.0 0.2 0.8 0.4 0.1 -0.1 0.6 -0.6 -0.8 0.1
Shortness of breath walking on level ground 0.4 0.5 1.8 0.6 0.4 0.3 1.3 0.7 1.3 0.5 0.0 0.5 0.4 0.3 0.5 0.2 -0.7 0.3 1.2 -0.6 1.1 0.3 0.5 -0.8 -1.3
Qualifications: College or University degree 0.2 0.7 4.1 0.3 0.6 0.0 0.0 0.6 -1.2 0.5 -0.2 0.4 0.1 1.3 -0.5 1.5 0.1 -0.7 -1.6 -2.0 0.0 -1.2 0.3 0.6 -0.6
Eye problems/disorders: None of the above 1.2 1.3 3.3 0.5 1.1 1.3 1.7 1.1 -0.5 -1.8 0.8 0.8 1.1 1.6 1.8 0.8 -1.1 -0.7 1.3 1.0 1.0 1.5 1.2 0.6 0.5
Mouth/teeth dental problems: Loose teeth 0.9 1.1 3.9 0.9 0.7 1.1 1.4 0.8 0.3 0.0 1.7 0.9 0.9 1.0 1.4 -0.0 -0.6 -0.7 1.1 2.0 -0.1 0.9 1.3 1.5 0.7
Emphysema/chronic bronchitis 0.3 0.4 1.5 -0.5 -0.9 -0.4 0.1 -1.2 -0.5 -0.4 0.2 -1.0 -0.4 -1.1 -0.3 0.3 0.3 0.7 -0.7 0.5 -0.8 -0.1 -0.4 -0.3 0.0
Medication for pain relief, constipation, heartburn 0.3 0.4 2.6 0.5 0.5 0.1 0.6 0.6 -1.1 1.4 -0.1 0.1 0.1 -0.0 -0.3 1.6 0.7 0.6 -0.1 -1.1 -0.3 0.3 -0.2 0.5 0.2
Neck or shoulder pain in last month 0.5 0.7 3.1 -0.5 -0.7 -1.0 0.2 -0.3 0.8 0.4 -0.1 -1.2 -1.4 -0.5 -1.3 -0.3 -1.2 -0.4 -0.3 -0.5 0.0 -1.3 -0.1 -1.8 -0.5
Medication: Blood pressure 0.7 1.3 5.6 0.7 -0.3 -0.6 0.5 0.6 -1.8 0.9 1.8 -0.4 -0.9 -0.9 0.9 1.0 -0.7 -1.0 -0.3 2.3 -1.5 1.0 0.5 0.4 2.4
Angina (self-reported) 1.0 1.4 8.5 1.3 1.0 0.5 2.9 2.0 1.3 -0.1 1.9 0.9 0.7 0.9 0.9 -0.5 -0.5 0.5 1.7 0.5 1.2 0.1 0.9 0.1 -0.1
Migraine (self-reported) 0.6 0.7 5.8 0.6 0.8 0.9 0.4 -0.6 -1.0 -1.2 -1.1 -1.1 -0.2 -0.8 0.2 0.0 -0.5 -0.2 0.4 0.2 -0.6 1.0 0.5 0.1 -2.4
Medication: Ibuprofen 0.2 0.2 1.0 0.4 -0.6 0.0 -1.0 -0.9 -0.2 0.6 -0.3 0.3 -0.1 1.0 0.1 -0.6 -0.3 -0.1 -0.7 0.4 -0.1 0.3 -0.4 0.1 -0.1
Medication: Allopurinol 0.5 0.6 2.0 -0.3 -0.6 0.3 -1.1 -1.3 1.0 -0.6 -0.5 0.2 -0.5 1.2 -0.7 -0.6 -1.3 -0.8 -1.4 -0.4 -1.0 -0.8 0.3 0.3 -0.0
Medication: Omeprazole 0.6 0.7 2.8 -0.5 -0.6 -0.3 0.3 0.7 0.6 1.5 0.9 -0.1 -0.5 -1.7 0.4 -0.8 1.2 1.3 0.5 1.4 0.6 0.6 -0.4 -0.8 0.2
Medication: Seretide 50 evohaler 0.6 0.7 3.7 0.5 0.5 0.7 -1.5 -1.9 -0.3 -1.2 -1.3 0.4 0.8 1.0 0.3 -0.5 -0.4 -0.3 0.3 0.3 1.3 1.2 0.2 -0.2 0.5
Mean time to correctly identify matches 0.7 1.3 4.0 -0.7 -0.7 -0.8 0.6 -0.1 0.4 -0.6 -2.0 -1.2 -0.9 -1.5 -1.8 -0.6 -0.9 -0.2 -0.8 -1.1 -1.9 -1.0 -1.4 -1.5 -1.3
Heart disease (mother) 1.2 1.4 4.3 1.4 1.3 1.2 0.3 0.7 -0.9 -1.2 0.6 0.9 1.3 0.6 1.1 0.7 0.9 1.2 2.1 1.1 1.8 0.9 1.4 1.5 -1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 1.0 9.7 -0.2 -1.0 -0.6 0.3 0.1 -0.2 -0.3 -0.2 -0.6 -1.0 -0.9 0.2 0.2 -0.4 -0.3 0.4 3.1 -1.7 0.5 0.1 0.4 2.2
Whole body fat mass 0.9 3.9 16.9 2.1 1.8 1.4 -0.8 -1.8 1.9 -4.1 -1.1 0.9 1.6 -1.6 1.7 0.9 2.3 3.3 2.0 -0.6 2.5 2.9 -0.2 2.1 -0.4
Leg fat mass (right) 0.9 3.5 14.2 2.5 1.9 1.9 -0.4 -1.5 2.0 -3.8 -0.8 1.0 1.5 -1.4 1.7 1.3 1.9 2.6 1.8 -0.2 1.9 3.1 0.3 2.2 -0.6
Arm predicted mass (right) 0.7 3.4 11.5 1.8 1.9 2.6 -1.2 -2.6 0.6 -3.4 -0.2 1.0 0.8 0.6 2.2 -0.6 -0.9 -0.9 1.5 2.8 1.0 3.1 2.2 2.2 0.2
Pulse rate, automated reading 1.1 3.5 19.3 1.9 -0.3 -0.5 -0.1 3.0 2.6 4.4 2.5 0.7 -0.4 -1.3 1.2 3.1 1.8 1.9 1.1 1.1 0.5 1.1 -0.4 0.5 2.8
Alcohol intake frequency. 0.5 1.2 4.0 -1.0 -2.0 -1.6 -0.6 -0.2 1.6 0.9 0.1 -1.3 -1.2 -0.3 -1.3 -1.1 0.2 0.3 0.2 -0.6 0.4 -0.4 -1.9 -1.9 0.5
Comparative height size at age 10 1.2 6.6 20.4 2.8 3.1 3.8 -0.6 -1.3 -0.5 -4.0 1.1 3.1 2.5 2.5 3.4 1.6 1.4 0.9 1.2 1.0 2.5 4.3 2.5 4.5 0.5
Number of full sisters 1.3 1.6 6.7 -1.7 -1.2 -1.2 0.6 -1.1 -0.9 -1.3 -2.1 -1.4 -0.5 0.3 -0.8 -2.6 -0.8 -0.2 0.1 -0.6 1.5 -1.2 -0.5 -2.3 0.1
Suffer from ‘nerves’ 0.7 1.1 7.0 0.7 0.5 1.7 -0.6 -0.5 0.4 -2.6 0.8 1.0 1.3 -0.4 1.5 -0.9 1.0 0.6 0.4 0.2 0.8 0.9 0.8 0.8 -1.6
Overall health rating 0.3 0.6 4.8 0.4 -0.1 -0.1 0.3 0.8 -0.2 2.2 1.9 0.2 -0.1 0.9 0.6 0.4 -0.2 0.3 1.0 1.1 0.5 0.2 0.4 -0.0 0.6
Chest pain or discomfort 0.3 0.4 1.4 0.1 -0.7 -0.1 0.8 -0.6 1.2 1.0 0.8 0.5 0.2 0.3 0.5 -0.5 -0.5 -0.2 -1.1 -0.0 -0.3 -0.7 -0.5 -0.8 -0.1
Had major operations 2.3 2.6 10.4 3.2 1.8 2.1 0.9 1.9 -0.6 -0.7 1.7 2.5 1.9 0.7 0.9 2.6 -0.2 -0.8 0.9 0.5 1.6 1.6 1.8 2.0 0.8
Age at last live birth 0.5 0.7 4.2 0.5 0.6 0.3 -0.0 -0.8 -1.2 0.2 -1.4 -1.2 -0.9 0.2 -0.5 -0.0 -0.5 -2.0 -0.8 -0.4 -1.4 -0.5 -0.1 -0.6 -1.1
Family relationship satisfaction 1.3 1.6 5.0 -2.2 -1.3 -1.4 -1.0 -1.5 -1.0 1.6 -0.2 -0.5 -1.4 -0.8 -1.4 -0.7 1.0 2.2 -1.5 -1.6 -0.4 -0.6 -1.6 -0.3 -0.6
Leg pain on walking 1.1 1.3 5.1 -0.4 -1.3 -1.2 -0.1 -1.6 2.3 -0.5 -1.3 -1.6 -1.9 -0.4 -1.6 -0.8 -0.7 -0.3 -1.3 0.6 -1.3 -0.5 -1.0 -0.5 1.1
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 2.2 1.1 1.0 0.7 0.4 -0.1 0.6 1.1 1.5 1.3 1.3 0.3 0.8 0.6 -0.1 -0.3 0.0 -1.2 0.9 0.0 0.2 1.1 -1.3
Commuting to job workplace: Car/motor vehicle 0.7 0.8 3.8 1.2 0.8 0.9 1.9 -0.5 -0.5 -0.7 0.1 0.5 0.4 0.4 1.7 -0.1 -1.0 -1.5 -0.6 0.6 -0.5 -0.1 0.8 0.2 -0.7
Illness, injury, bereavement, stress in last 2 years 0.6 0.8 5.8 -0.9 1.1 0.4 1.1 1.0 0.5 -0.6 0.3 0.7 0.8 0.7 -0.1 -0.0 -0.7 -0.8 -0.1 -1.4 0.4 -0.6 0.8 0.6 -2.4
Medication: Aspirin 0.5 0.6 2.7 -0.9 -0.3 -0.6 -0.1 -0.7 -0.3 -1.0 0.0 -0.8 -0.6 -0.5 0.0 -1.6 -1.6 -1.1 -0.3 0.7 -0.7 -0.5 -0.2 -0.9 0.8
Supplements: Vitamin C 1.7 2.1 6.8 1.6 2.3 1.8 2.6 0.4 -1.1 -1.6 -0.3 1.6 2.4 1.8 1.4 0.1 -1.2 -1.4 1.1 -0.5 1.0 0.4 1.5 0.8 -1.0
Knee pain experienced in last month 0.3 0.5 2.4 -0.1 0.0 -0.2 0.5 -0.6 1.0 -0.7 -1.1 -0.5 -0.0 -1.1 -0.5 0.8 -0.4 -0.1 -0.3 -1.6 0.6 -0.0 -0.8 -0.9 -0.2
Hypertension (Self-reported) 1.0 2.9 21.5 -0.8 -1.7 -1.6 -0.3 -1.0 0.6 -0.2 1.3 -1.7 -2.3 -1.3 -0.5 -1.8 -0.5 -1.2 0.1 4.6 -3.2 0.4 0.1 -1.3 2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 1.0 2.6 -1.3 -1.2 -1.4 -1.6 0.5 0.7 0.8 -0.3 -0.9 -1.0 -1.1 -0.9 -0.3 1.3 1.4 -0.3 -0.1 0.1 -0.2 -1.5 -1.1 0.9
Illnesses of father: Heart disease 0.2 0.2 1.4 0.2 -0.6 -0.2 -0.4 -0.8 -0.4 0.6 0.7 0.1 -0.3 -1.2 0.1 -0.2 0.0 0.1 -0.1 0.5 -0.2 0.1 -0.3 -0.3 0.7
Illnesses of siblings: Diabetes 0.4 0.4 1.8 0.4 -0.1 -0.1 -0.3 0.2 1.1 -0.4 -1.1 -0.4 0.5 -1.4 -0.8 -1.2 1.0 0.8 -0.3 -0.2 0.3 0.1 -0.5 -0.2 -0.7
Smoking status: Previous 1.2 1.8 12.8 0.6 1.2 0.5 -0.8 -1.6 -1.4 -3.6 -0.7 0.7 1.4 1.6 -0.6 -0.8 -0.5 -1.4 -1.2 -1.7 0.8 -1.7 1.6 -0.1 -0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.8 1.7 7.2 1.5 2.1 2.6 -0.2 -0.6 -1.2 -0.6 0.1 0.8 1.1 1.2 1.4 1.7 0.0 0.4 1.2 1.2 0.8 2.7 0.6 1.9 -0.4
Whole body fat-free mass 0.5 3.1 12.0 1.5 2.0 2.1 -1.1 -2.8 1.1 -3.5 -0.3 0.8 0.5 1.5 2.1 -0.6 -1.1 -0.9 1.3 2.5 1.0 2.7 2.2 2.0 0.6
Leg fat-free mass (right) 0.5 2.8 12.4 1.2 1.8 1.5 -0.8 -2.9 1.3 -3.5 -0.2 0.5 0.7 1.5 2.2 -1.2 -0.7 -0.5 1.9 2.1 1.6 2.1 2.1 1.3 0.5
Arm fat percentage (left) 0.7 2.7 13.7 1.2 0.8 -0.2 0.0 -1.3 2.3 -3.1 -0.8 0.1 0.9 -2.0 0.8 0.3 2.7 3.7 2.0 -1.0 2.1 1.5 -0.8 0.8 -0.0
Average weekly red wine intake 0.8 1.2 3.7 0.2 1.2 1.6 0.3 -0.1 0.6 0.7 1.3 1.4 0.6 1.1 -0.4 -0.4 -1.6 -1.9 0.1 -0.6 1.4 -0.6 1.9 0.4 -1.8
Handedness (chirality/laterality): Left-handed 0.9 1.1 3.9 -0.5 -0.5 -0.7 -1.3 0.2 0.5 -0.2 -0.7 -0.5 -1.1 0.5 -2.0 0.2 -1.4 -2.0 -1.7 -1.3 -1.0 -1.3 -0.5 -1.1 0.9
Mood swings 0.4 0.7 7.0 0.4 0.8 0.9 1.0 0.3 -1.0 -1.3 0.0 -0.0 0.6 -1.0 -0.1 0.2 -0.3 -0.2 -0.1 -0.4 -0.8 0.4 0.1 0.7 -2.6
Loneliness, isolation 0.6 0.8 3.0 -0.4 -1.0 -0.7 0.3 -0.6 0.5 0.3 1.3 -1.3 -1.4 -0.6 -0.4 -1.5 -1.0 -0.4 0.8 1.7 -0.5 0.4 0.3 -1.4 0.0
Long-standing illness, disability or infirmity 0.6 0.9 3.2 -1.0 -1.7 -1.2 -1.5 -0.2 0.4 1.6 1.8 -0.7 -1.2 -0.6 -0.9 -0.8 -0.2 -0.2 -0.1 0.1 -0.0 -1.0 -0.8 -1.3 -0.5
Ever had bowel cancer screening 0.7 0.8 4.4 -0.5 0.4 0.4 -0.1 0.7 0.2 -2.1 -0.7 -0.1 0.1 -1.0 0.2 -1.4 -1.4 -1.4 -0.5 -1.0 1.1 -0.5 0.3 -0.8 -1.0
Diabetes diagnosed by doctor 1.9 3.0 11.0 -2.1 -2.6 -2.7 -1.9 -0.9 0.3 -0.3 -1.3 -2.2 -1.9 -1.5 -2.6 -1.5 0.6 1.1 0.1 0.1 -0.5 -1.4 -2.2 -3.3 1.5
Ever had stillbirth, spontaneous miscarriage or termination 1.5 1.6 3.8 -1.5 -1.1 -1.1 -1.5 -0.7 -0.5 1.9 -0.8 -1.3 -1.8 -0.3 -1.5 -1.1 -1.7 -1.7 -1.9 -0.2 -1.3 -1.6 -0.3 -1.2 0.4
Friendships satisfaction 0.5 0.7 4.5 -0.0 1.5 0.3 2.1 -0.1 -0.8 -0.0 1.4 0.8 -0.3 0.7 1.0 0.1 -0.4 -0.2 0.0 -0.2 0.3 0.2 1.4 0.4 0.2
Qualifications: nursing, teaching 0.5 0.8 5.5 -0.1 -0.1 0.0 -0.4 -1.0 0.9 0.4 -0.2 0.3 0.3 1.2 0.2 -0.5 -0.2 -1.1 -1.9 -2.3 0.5 -1.6 -0.5 -0.7 -0.2
Commuting to job workplace: Walk 0.5 0.6 2.2 1.0 0.0 0.8 -0.4 0.3 0.8 0.2 0.5 0.9 0.8 0.2 0.4 0.8 -0.5 0.5 1.0 1.2 0.3 1.4 0.3 1.5 0.5
Eye problems/disorders: Cataract 0.7 0.8 2.4 -0.3 0.1 -0.9 -0.7 -0.2 1.2 0.8 -0.8 0.3 0.3 -0.9 -1.6 -1.1 0.9 0.4 -0.5 -1.5 0.8 -1.5 -0.4 -1.2 -0.9
Mouth/teeth dental problems: Mouth ulcers 1.9 3.1 18.1 1.8 2.0 1.2 2.7 1.9 -1.6 1.6 1.6 1.9 1.1 4.3 1.6 0.8 -1.2 -2.8 0.2 -1.0 -0.0 -0.9 1.6 0.9 0.6
Medication for cholesterol 1.0 1.5 12.7 -0.6 -0.2 -0.7 0.3 0.7 -0.4 0.8 -1.3 -0.1 0.2 0.5 -1.0 1.5 0.4 1.5 -1.3 -3.6 0.2 -0.9 -2.0 0.2 -1.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.1 8.3 -1.2 0.1 -0.3 0.8 0.2 -1.3 0.4 -0.4 -1.2 -0.6 -0.5 -1.3 0.3 0.5 0.4 -0.7 -2.0 -0.6 -0.7 -1.4 -0.4 -2.9
Back pain experienced in last month 0.3 0.4 4.1 0.3 0.8 0.7 0.7 -0.5 0.5 -0.3 0.6 -0.3 0.1 -0.5 0.5 0.4 0.6 -0.1 0.4 0.4 0.2 0.8 0.3 0.5 -2.0
Mineral and other dietary supplements 1.3 1.8 7.7 -0.3 -1.0 -1.1 -0.4 1.0 -0.1 1.9 1.7 0.5 0.4 0.1 1.1 1.9 2.2 2.8 1.4 0.4 0.6 1.0 -0.9 0.9 2.5
Breast cancer (self-reported) 0.9 1.0 3.5 -0.5 -0.7 -1.5 -0.2 1.1 0.1 1.9 0.3 -0.8 -0.9 -0.3 -1.5 -0.5 -0.9 -1.4 -0.9 0.9 -1.5 -0.9 -0.1 -1.3 1.4
Asthma (self-reported) 1.2 2.4 5.7 -1.9 -2.4 -2.1 -1.3 -1.8 1.0 -2.0 -1.8 -1.9 -1.1 -0.6 -1.5 -1.2 1.2 2.1 0.9 -0.1 1.3 -0.4 -1.1 -2.4 1.2
Osteoporosis (self-reported) 1.9 2.4 11.3 -1.7 -2.1 -2.2 -1.4 -1.0 -0.4 0.8 0.2 -1.4 -2.1 -1.8 -0.2 0.3 2.7 3.4 0.6 1.3 0.7 0.5 -1.8 -0.5 1.6
Osteoarthritis (self-reported) 0.4 0.5 2.0 0.6 0.8 0.9 -0.5 -0.9 0.2 -0.8 -0.7 0.4 0.2 -1.4 0.1 0.4 -0.4 -0.7 -1.3 -0.8 0.4 0.5 0.2 1.0 -1.1
Medication: Aspirin 0.3 0.4 2.0 -0.1 0.5 -0.1 0.6 -0.1 -0.6 -1.0 0.1 -0.4 -0.3 -0.1 0.8 -1.0 -1.4 -1.0 0.5 0.6 0.0 0.3 0.0 -0.7 0.5
Medication: Gliclazide 0.3 0.4 1.7 0.5 -0.2 -0.3 -0.3 0.9 0.7 -1.0 -0.6 -0.7 0.1 -0.9 -0.7 0.3 -0.4 0.3 1.3 0.5 -0.1 0.4 -0.0 -0.5 0.1
Illnesses of father: None of the above (group 1) 0.3 0.3 1.1 0.3 0.9 0.2 1.1 0.7 0.3 -0.7 -0.4 0.2 0.9 -0.0 0.6 -0.3 -0.2 0.1 0.7 0.2 0.9 0.7 0.5 0.2 -0.6
Smoking status: Current 1.1 1.8 5.9 -0.2 -1.0 -0.2 0.1 0.0 -1.7 -1.0 1.7 -0.2 -0.4 -1.1 0.8 0.2 1.6 2.2 0.8 2.4 -1.5 2.3 -1.0 1.8 1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.0 7.0 1.3 0.9 0.7 -1.1 1.7 1.2 -0.4 -0.9 0.6 1.1 -0.9 0.6 2.6 0.6 0.6 1.0 -0.6 0.6 1.0 -0.2 0.4 -0.1
Whole body water mass 0.5 3.1 12.5 1.4 1.9 2.0 -1.1 -2.8 1.1 -3.5 -0.3 0.7 0.4 1.5 2.0 -0.7 -1.2 -1.0 1.3 2.6 1.0 2.5 2.2 1.9 0.8
Leg predicted mass (right) 0.5 2.7 13.1 1.1 1.6 1.4 -0.9 -3.0 1.2 -3.6 -0.3 0.3 0.6 1.4 2.1 -1.4 -0.7 -0.5 1.8 2.2 1.5 2.1 2.1 1.2 0.6
Arm fat mass (left) 0.6 2.5 15.1 1.7 1.5 0.9 -0.4 -1.9 2.4 -3.9 -0.8 0.5 0.9 -1.0 1.5 0.0 1.5 2.2 1.5 0.0 1.6 2.1 0.2 1.6 -0.1
Number of self-reported non-cancer illnesses 0.7 1.3 8.9 0.6 -0.8 -0.7 0.3 1.0 1.9 -0.0 0.3 -1.0 -0.3 -3.0 -0.3 0.4 1.7 1.7 1.6 0.5 0.1 0.8 -0.1 -1.1 -0.9
Average weekly champagne plus white wine intake 2.2 3.1 9.0 1.6 1.8 1.7 -0.4 2.8 -1.5 1.2 2.6 3.0 1.8 2.5 1.4 1.4 -0.6 -1.2 1.6 0.6 2.0 0.6 2.5 1.4 0.8
Miserableness 0.8 1.4 4.6 -2.0 -1.6 -1.3 -1.6 -0.3 0.2 -0.1 0.4 -0.7 -1.1 0.4 -1.4 -2.0 0.3 -0.0 -1.1 -0.6 -1.4 -2.1 -1.2 -1.3 -0.4
Guilty feelings 0.8 1.2 5.6 -0.2 0.2 0.7 0.1 -1.2 0.4 -2.2 -0.3 -0.3 0.1 1.6 0.1 -1.7 -2.4 -1.8 0.1 1.3 -0.0 -0.4 1.3 -0.2 -0.5
Wears glasses or contact lenses 0.8 0.9 3.5 -0.4 -0.1 -0.7 -1.4 0.8 -1.3 0.7 0.1 0.9 0.5 -0.5 -1.6 1.1 0.5 0.4 -0.1 -1.9 1.2 -1.4 -0.1 -0.8 1.3
Ever taken oral contraceptive pill 2.1 2.4 6.4 1.5 2.1 1.5 1.7 -0.5 -1.4 -1.1 1.0 2.1 1.1 2.0 2.1 2.1 0.6 1.0 0.3 0.3 1.4 1.2 1.8 2.5 1.7
Hearing aid user 10.1 11.4 30.6 5.5 5.3 5.1 2.5 3.9 -0.7 1.3 2.8 4.4 4.5 1.2 3.7 3.6 0.8 0.1 2.5 -0.2 2.3 3.4 4.2 4.7 -2.2
Mother’s age at death 0.8 1.0 3.1 -1.3 -1.2 -0.9 -0.9 -1.6 0.9 -0.6 -1.4 -0.5 0.1 -0.2 -1.0 -1.3 -0.3 0.1 -1.1 -1.7 0.6 -1.2 -1.3 -1.1 -0.5
Financial situation satisfaction 0.3 0.4 1.3 -0.2 1.0 0.7 -0.3 -0.8 0.6 -0.7 -0.1 0.7 0.7 -0.8 0.1 -0.7 -0.1 0.9 0.8 -0.4 0.4 0.8 -0.2 -0.0 -1.1
Tinnitus: Yes, now most or all of the time 3.8 4.4 10.8 2.2 3.0 2.3 0.0 2.4 -0.5 -0.7 2.5 3.1 2.3 2.6 1.8 2.6 0.2 -0.4 1.0 -0.6 3.1 1.9 2.8 3.3 0.6
Commuting to job workplace: Public transport 0.6 0.7 5.0 0.7 -0.1 0.2 -0.2 1.0 0.6 2.2 0.5 0.7 0.8 -0.4 0.2 1.6 -0.1 1.2 0.9 -0.1 0.6 0.9 -0.3 1.2 0.6
Eye problems/disorders: Glaucoma 1.0 1.2 5.0 0.4 -0.3 -0.4 0.3 0.4 -1.0 1.1 0.4 -0.8 -1.0 -1.7 0.4 1.8 1.3 1.7 -0.9 -0.6 -2.2 0.8 -1.7 0.9 -0.5
Medication: Blood pressure 1.5 2.9 18.2 -1.1 -1.5 -1.0 -0.2 -2.1 1.9 -2.1 0.2 -1.6 -2.0 -0.8 -0.4 -3.0 -0.5 -1.2 0.5 4.3 -2.3 0.2 0.5 -1.2 1.7
Pain type(s) experienced in last month: Hip pain 0.5 0.6 2.0 0.1 -1.0 -0.3 0.2 0.4 1.4 0.1 1.2 -0.3 -1.1 -1.3 -0.1 -1.0 0.0 -0.1 0.9 1.2 0.4 -0.1 0.0 -0.8 1.1
Supplements: Fish oil (including cod liver oil) 2.8 3.7 13.2 -0.6 0.4 0.5 -0.2 -2.4 0.7 -2.7 -3.6 -1.4 -0.8 -0.4 -1.8 -2.9 -2.5 -3.0 -2.1 -0.9 -1.1 -1.7 0.3 -2.4 -2.8
High cholesterol (Self-reported) 0.8 1.4 8.5 -1.6 -1.6 -1.9 -1.3 -0.5 -0.8 -0.7 -1.4 -0.7 -1.1 -1.0 -1.3 -0.4 0.4 0.3 0.3 0.4 0.6 -0.5 -0.7 -1.4 2.9
Medication: Bendroflumethiazide 2.0 3.0 11.2 -2.1 -2.0 -2.4 -0.4 -1.4 0.2 -0.6 -1.2 -2.8 -3.3 -1.5 -1.7 -2.0 -0.4 -0.4 -0.5 2.5 -3.0 -0.7 -0.7 -1.5 1.5
Medication: Paracetamol 0.3 0.5 1.5 0.4 0.8 0.4 0.1 -0.3 1.0 -1.2 -0.8 0.8 1.0 0.9 1.1 -0.4 0.7 0.7 -0.1 0.2 0.9 0.1 0.5 0.1 -0.7
Medication: Lisinopril 1.8 2.4 11.0 1.0 -0.1 -0.6 -0.4 0.5 0.9 0.2 1.4 0.1 -0.2 -0.3 1.4 0.1 1.6 1.9 2.4 3.3 1.6 3.2 0.8 0.3 3.1
Medication: Atorvastatin 0.8 1.0 3.7 1.1 0.6 0.6 -0.9 -1.0 1.2 -1.5 -0.3 0.6 -0.2 0.5 -0.2 0.5 -1.4 -1.9 0.0 1.4 0.4 -0.4 1.9 -0.2 1.1
Illnesses of father: High blood pressure 1.4 1.7 8.1 -0.6 -0.6 -0.0 -0.5 -2.2 -1.2 -1.0 0.4 -0.4 -1.5 1.6 -0.4 -0.7 -1.4 -1.6 -2.2 1.1 -2.8 -1.3 0.2 1.4 0.3
Alcohol drinker status: Never 1.1 1.4 5.3 1.5 1.1 1.1 1.6 -0.1 0.1 -0.5 -0.2 1.4 1.5 1.3 0.9 -0.3 -2.3 -2.3 0.4 -1.0 1.0 -0.4 1.0 -1.2 -0.7
Ever smoked 0.8 1.4 13.6 0.6 1.0 0.8 -0.6 -1.0 -1.6 -3.7 0.6 1.1 1.4 0.9 0.2 -0.6 0.3 -1.1 -1.2 -0.8 -0.3 -0.6 1.2 1.1 0.8
Basal metabolic rate 0.6 3.3 15.2 1.7 2.0 2.1 -1.2 -2.9 1.4 -3.9 -0.5 0.7 0.6 1.1 2.2 -0.5 -0.6 -0.3 1.4 2.3 1.2 2.9 2.0 2.1 0.6
Leg fat percentage (left) 0.8 3.0 11.7 2.0 1.1 1.0 0.1 -0.7 2.2 -3.1 -1.1 0.4 1.0 -2.8 1.0 1.3 2.8 3.4 1.6 -0.4 1.1 2.5 -0.7 1.4 -0.8
Arm fat-free mass (left) 0.6 3.2 14.0 1.6 1.8 2.4 -1.3 -2.6 1.6 -3.7 -0.8 0.6 0.4 0.7 1.8 -0.6 -1.4 -1.1 0.7 2.9 0.0 2.8 1.9 2.3 0.3
Number of operations (self-reported) 0.7 1.1 6.7 0.4 0.5 0.6 -1.3 0.1 -1.2 -2.2 -0.4 -0.0 -0.2 -2.6 -0.4 0.8 1.0 1.1 0.0 1.1 0.4 1.4 0.2 1.1 -0.0
Average weekly beer plus cider intake 0.9 1.2 4.2 0.9 1.2 1.8 1.0 -0.9 -0.5 -0.8 -0.2 0.5 1.1 2.0 1.6 -0.1 -0.9 -1.4 -1.4 -0.3 -1.0 0.0 1.2 1.0 -1.6
Irritability 0.9 1.4 16.2 1.0 1.1 1.4 1.5 -0.2 -0.9 -1.6 -0.0 -0.0 1.1 0.3 0.2 0.1 -0.0 -0.6 -0.3 -0.8 -1.6 0.2 0.1 0.7 -4.0
Risk taking 0.8 1.1 10.3 -0.2 -0.5 -0.1 0.5 -1.8 -3.2 -0.5 0.1 -1.0 -0.7 0.5 0.5 0.1 -1.5 -0.7 -1.6 0.8 -1.4 -0.1 0.0 -0.0 -0.7
Ever had prostate specific antigen (PSA) test 0.5 0.6 2.6 -0.2 -0.6 -0.3 -0.8 -0.6 0.2 -0.9 -0.5 -0.8 -0.6 0.2 -0.1 0.0 -1.6 -0.9 0.4 1.4 0.0 0.8 0.3 -1.1 1.1
Fractured/broken bones in last 5 years 2.5 3.2 8.7 0.8 1.5 1.0 -1.1 -0.9 -1.8 -1.9 1.3 2.1 2.1 1.2 3.0 0.4 2.6 2.4 1.5 0.9 2.6 2.6 1.3 1.9 1.6
Age started oral contraceptive pill 0.5 0.7 2.7 0.5 1.1 0.5 0.8 1.1 1.1 -0.7 0.5 1.1 1.3 0.0 0.7 -0.1 -0.0 0.3 1.1 -0.3 1.6 0.2 0.9 0.6 -0.8
Diastolic blood pressure, automated reading 1.1 3.6 17.8 0.1 -2.1 -1.7 -1.2 2.1 1.8 3.3 -0.6 -1.1 -1.8 -1.4 -1.0 1.7 1.3 1.3 1.2 3.4 -1.2 1.7 -1.2 -0.0 4.2
Ever depressed for a whole week 1.2 1.4 8.5 0.7 1.0 0.3 2.9 2.2 1.8 1.1 1.4 0.2 0.2 0.7 0.3 0.2 -1.7 -1.3 0.3 0.7 -1.0 -0.2 1.0 0.3 -1.4
Unable to work because of sickness or disability 0.5 0.6 3.2 -0.1 0.1 0.0 -1.1 -0.7 -0.1 -0.6 0.9 0.8 0.4 1.8 0.8 -0.4 1.0 0.9 0.7 -0.1 1.6 0.2 0.1 -0.0 0.9
Commuting to job workplace: Cycle 3.4 4.1 10.0 -3.2 -2.9 -2.2 -2.6 -2.3 -0.9 -2.2 -1.6 -2.4 -1.9 -2.1 -2.4 -2.7 0.1 -1.0 -2.0 -0.2 -1.4 -1.9 -1.3 -2.6 0.5
Myopia 1.0 1.4 10.3 -0.5 0.2 0.1 -0.4 0.6 -0.4 1.1 1.1 1.1 0.8 3.2 0.2 0.0 -0.8 -1.5 -1.8 -2.0 -0.5 -2.0 0.3 -0.1 -0.5
Vascular/heart problems diagnosed by doctor 1.2 3.1 16.4 1.6 2.0 2.1 0.1 1.2 -0.7 0.5 -1.1 2.0 2.7 1.3 0.6 2.4 0.6 0.9 0.1 -4.1 2.8 0.1 0.4 1.9 -2.6
Cholesterol lowering medication 0.9 1.4 6.6 0.4 0.9 1.0 -0.6 0.6 -1.1 -0.5 0.8 1.6 1.1 -0.3 0.7 0.3 1.1 0.8 2.6 1.3 2.1 1.2 1.4 0.2 1.6
Medication: Omeprazole (e.g. Zanprol) 0.8 0.9 3.5 -1.0 -0.9 -0.6 0.4 0.3 0.5 0.9 0.8 -0.7 -0.7 -1.9 0.2 -1.1 1.7 1.8 0.8 1.1 0.5 0.7 -0.8 -1.2 0.3
Pain experienced in last month 0.6 1.0 6.2 -0.6 -0.4 -0.7 -1.8 0.7 -1.0 0.8 -0.2 0.4 -0.1 2.3 -0.2 0.2 -0.9 -1.0 -0.7 -0.5 0.4 -0.6 -0.1 -0.2 2.5
Supplements: Calcium 0.9 1.0 4.4 0.6 0.5 0.1 0.4 0.0 -0.8 -2.1 -0.1 0.5 0.2 0.8 0.7 -1.4 -0.9 0.1 1.7 2.0 1.4 1.0 0.9 0.3 1.1
Basal cell carcinoma (self-reported) 1.0 1.1 14.7 0.2 -0.3 -0.2 -0.8 -0.5 3.8 0.4 -0.4 -0.7 -0.3 -0.3 -0.7 -0.9 -1.1 -0.7 -0.6 0.7 -1.1 -1.1 -0.3 -0.1 -1.4
Heart attack/myocardial infarction (self-reported) 1.0 1.3 4.3 -1.7 -0.7 -1.7 0.3 -0.2 -0.4 0.0 -1.2 -1.1 -0.4 -0.4 -1.1 -1.0 -0.9 0.4 -0.7 -2.1 0.6 -1.6 -1.9 -2.1 0.5
Deep venous thrombosis (DVT) (self-reported) 1.1 1.4 4.2 1.2 1.3 1.7 -0.5 -1.3 0.5 -1.3 1.1 1.2 1.5 1.1 2.0 -1.0 -0.4 -0.2 1.6 0.5 1.5 1.4 1.3 -0.3 -0.1
Heart disease (siblings) 0.9 1.1 5.4 -1.9 -0.6 -1.1 0.1 -0.5 0.2 -0.1 -0.1 -0.4 -0.4 -0.8 0.0 -2.3 1.3 1.5 0.4 -0.8 1.8 -1.4 -0.8 -1.2 0.5
Alcohol drinker status: Previous 1.0 1.1 3.9 -1.8 -1.6 -1.0 -2.0 -0.7 0.1 -0.1 -1.0 -0.9 -1.6 0.7 -1.5 -1.3 0.1 0.5 -0.3 -0.3 -0.2 -0.7 -1.4 -1.2 0.2
Pack years of smoking 0.7 1.0 4.2 0.7 -0.1 -0.2 0.6 1.1 -1.1 0.7 0.1 0.1 0.8 -0.9 1.0 1.0 1.2 2.1 1.5 0.3 -0.4 1.9 -1.2 0.7 0.3
Impedance of whole body 0.6 3.1 15.5 0.3 -0.3 -0.1 -1.3 1.9 -1.7 1.0 0.2 1.3 1.1 -0.4 0.2 2.7 3.6 3.9 0.6 -2.7 2.4 0.6 -1.8 0.9 1.7
Leg fat mass (left) 0.9 3.6 15.6 2.4 1.9 1.9 -0.5 -1.8 1.8 -4.0 -1.1 0.9 1.4 -1.6 1.6 1.0 2.0 2.7 1.9 -0.0 1.9 3.1 0.3 2.0 -0.8
Arm predicted mass (left) 0.6 3.2 13.8 1.8 1.8 2.4 -1.5 -2.7 1.3 -3.7 -1.0 0.6 0.4 0.6 1.7 -0.3 -1.3 -0.9 0.9 2.8 0.2 3.0 1.8 2.1 0.3