Best TWAS P=5.94e-12 · Best GWAS P=1.37e-21 conditioned to 1.22e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | SLC12A7 | 0.17 | 0.07 | enet | 6 | 0.11 | 2.1e-09 | 5.5 | 5.3 | 1.0e-07 | -0.02 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | SLC12A7 | 0.16 | 0.04 | lasso | 3 | 0.04 | 3.9e-04 | 5.8 | -5.2 | 1.7e-07 | 0.04 | 0.39 | 0.02 | FALSE |
| 3 | GTEx | Lung | SLC12A7 | 0.26 | 0.12 | enet | 14 | 0.12 | 2.0e-09 | 5.5 | 6.0 | 1.9e-09 | -0.04 | 0.99 | 0.00 | FALSE |
| 4 | GTEx | Whole Blood | SLC12A7 | 0.40 | 0.19 | enet | 10 | 0.25 | 1.7e-22 | 4.7 | 5.7 | 1.2e-08 | -0.02 | 1.00 | 0.00 | FALSE |
| 5 | METSIM | Adipose | SLC12A7 | 0.16 | 0.14 | lasso | 2 | 0.13 | 3.7e-19 | 5.8 | 5.8 | 6.5e-09 | -0.03 | 1.00 | 0.00 | FALSE |
| 6 | YFS | Blood | SLC12A7 | 0.02 | 0.01 | enet | 23 | 0.02 | 6.0e-07 | 4.7 | 6.9 | 5.9e-12 | 0.11 | 0.99 | 0.00 | TRUE |