Hub : Genes

SLC12A7

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0540 0.0220 6.0e-03 0.006 0.017 -0.002 0.015 0.007 6.0e-02 2.9e-03 7.1e-01 4.7e-03 4.2e-02
2 GTEx Adipose Subcutaneous 0.1740 0.0520 6.7e-04 0.067 NA 0.112 NA 0.104 3.9e-06 NA 2.1e-09 NA 7.1e-09
3 GTEx Cells Transformed fibroblasts 0.1630 0.0530 6.1e-04 0.045 NA 0.030 NA 0.042 2.7e-04 NA 2.3e-03 NA 3.9e-04
4 GTEx Lung 0.2580 0.0682 1.0e-03 0.117 NA 0.120 NA 0.111 2.9e-09 NA 2.0e-09 NA 8.1e-09
5 GTEx Whole Blood 0.3990 0.0570 2.1e-13 0.190 NA 0.246 NA 0.244 3.0e-17 NA 1.7e-22 NA 2.2e-22
6 METSIM Adipose 0.1585 0.0336 1.5e-09 0.135 0.067 0.115 0.123 0.132 1.2e-19 3.0e-10 7.3e-17 5.6e-18 3.7e-19
7 YFS Blood 0.0228 0.0083 4.2e-04 0.014 0.011 0.019 0.014 0.014 1.4e-05 1.2e-04 6.0e-07 1.6e-05 1.3e-05
8 TCGA Kidney Renal Clear Cell Carcinoma 0.0987 0.0425 2.6e-03 0.019 0.006 0.038 NA 0.036 2.6e-03 5.9e-02 3.9e-05 NA 5.9e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.1 0.2 1.2 -0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0
Bipolar Disorder or Schizophrenia 0.0 0.0 0.1 -0.3 0.0 0.0 0.0 0.0 0.0 -0.2 0.0
Depressed Affect (Nagel 2018) 0.4 0.9 3.0 0.3 0.6 -0.5 1.5 0.5 1.0 -0.0 1.7
Depression (Nagel 2018) 1.0 1.5 3.1 0.0 1.3 -1.2 1.4 1.2 1.1 1.0 1.8
Intelligence (Savage-Jansen 2018) 0.3 1.1 2.2 0.2 -0.9 1.5 -1.0 -1.1 -1.5 -1.0 -0.3
Neuroticism (Nagel 2018) 0.6 1.5 3.2 0.6 1.1 -0.7 1.7 1.1 1.1 1.0 1.8
Schizophrenia (2018) 2.4 5.0 8.0 0.8 -2.7 2.4 -2.5 -2.6 -2.8 -2.2 0.0
Schizophrenia vs Biploar Disorder 0.1 0.1 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Worry (Nagel 2018) 1.4 3.0 5.6 0.0 2.0 -1.6 2.4 2.1 1.8 1.9 0.7
Alzheimer’s Disease (in mother) 2.3 2.7 4.7 0.9 -1.8 1.6 -1.8 -1.7 -2.2 -1.8 0.6
Alzheimer’s Disease (in father) 0.8 0.9 1.5 -0.5 1.1 -1.1 0.9 0.9 1.2 0.7 0.9
Alzheimer’s Disease (including proxy) 0.8 1.2 2.8 -0.8 -1.1 0.8 -1.1 -1.1 -1.3 -1.7 0.5
Crohns Disease (2017) 1.1 2.4 4.2 -0.0 -1.9 1.5 -1.9 -1.8 -2.1 -0.7 1.2
Irritable Bowel Disease (IBD) 0.4 1.0 3.5 -0.3 -1.0 0.7 -1.9 -0.9 -1.4 0.0 0.3
Ulcerative Colitis (UC) 0.3 0.6 1.9 -0.3 1.0 -0.9 0.0 0.9 0.6 1.4 -0.2
Major Depression (MDD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Reaction Time 3.1 5.9 9.1 1.6 2.7 -2.8 2.2 3.0 3.0 2.6 -0.1
Verbal and Numeric Reasoning (VNR) 0.7 1.8 2.7 -0.1 -1.6 1.6 -1.4 -1.5 -1.6 -1.4 -0.8
Breast Cancer 1.2 2.9 5.7 -1.0 2.1 -1.6 1.6 1.7 1.6 2.4 -1.2
Ovarian Cancer 1.9 2.5 7.2 0.0 1.7 -1.4 2.7 1.4 2.3 0.4 -0.6
Prostate Cancer 0.5 0.7 1.7 -1.1 -0.8 1.3 -0.1 -0.5 -1.1 0.2 0.3
Age at First Birth 0.6 0.9 3.7 -1.5 0.7 -0.0 0.8 0.4 0.6 -0.1 1.9
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.1 0.1 0.3 0.5 0.0 -0.1 -0.2 0.1 0.2 -0.6 0.0
Coronary Artery Disease (CAD) 0.1 0.1 0.9 -0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 0.0 0.0 0.3 -0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0
Mean Putamen Volume 0.7 0.8 1.4 0.7 -1.2 1.2 0.0 -0.9 -0.9 -1.0 0.7
Fasting Glucose 0.1 0.1 0.3 -0.2 0.4 0.2 -0.3 0.5 -0.5 -0.1 -0.3
HbA1C 0.5 0.5 2.4 -1.5 0.4 -0.0 0.1 0.2 -1.1 0.4 0.0
HDL Cholesterol 1.7 2.8 4.8 0.3 -2.0 1.9 -1.9 -2.2 -1.8 -1.7 0.0
LDL Cholesterol 0.3 0.5 2.3 -0.3 -0.7 0.7 -0.1 -0.8 -0.4 -1.5 0.0
Lupus 0.6 0.9 2.5 -0.5 1.1 -0.8 1.0 1.0 0.4 1.6 -0.8
Neuroticism (2016) 0.8 1.2 2.3 -0.2 1.1 -1.5 0.7 1.3 1.3 1.2 0.3
Primary Biliary Cirrhosis 6.4 9.1 14.3 -2.4 3.4 -2.9 3.2 3.8 3.4 3.2 0.7
Rheumatoid Arthritis 0.1 0.1 0.5 0.4 -0.1 -0.2 -0.7 -0.1 -0.1 -0.0 0.0
Schizophrenia (2014) 0.6 1.2 2.0 0.8 -1.2 1.1 -1.4 -1.2 -1.2 -1.2 0.0
Triglycerides 0.7 1.2 2.4 -0.8 1.2 -1.1 0.6 1.5 1.1 1.5 0.0
Type 2 Diabetes (T2D) (2012) 1.4 1.6 3.4 -1.0 0.0 -1.5 1.9 1.5 1.4 1.4 0.0
Ulcerative Colitis 0.1 0.1 1.0 -1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Blood Eosinophil Count 0.1 0.6 2.0 1.4 -0.7 0.1 -0.2 -0.8 -0.0 -1.3 0.2
Blood Platelet Count 0.5 5.9 13.9 -1.1 -3.6 1.1 -2.6 -2.8 -3.7 1.5 0.8
Blood Red Count 10.4 100.5 132.2 -7.8 11.2 -10.5 10.9 11.4 11.5 10.4 4.2
Blood White Count 3.6 26.4 47.3 -0.5 5.3 -5.2 6.0 5.7 5.8 6.9 2.4
Heel T-Score 0.4 2.9 5.4 0.6 -1.9 1.6 -0.7 -1.8 -2.3 -1.6 -2.2
BMI 0.1 0.5 1.0 -0.6 1.0 -0.9 0.5 0.7 0.7 0.2 -0.7
Height 0.0 0.6 1.6 -0.8 0.4 -0.4 0.3 0.4 0.8 1.3 -1.0
Waist Hip Ratio (WHR) 0.5 2.2 4.2 -1.7 1.6 -1.3 0.7 1.8 1.5 2.0 0.6
Systolic Blood Pressure 0.0 0.1 0.2 0.0 -0.1 0.0 -0.2 0.4 0.5 -0.1 0.1
Smoking Status 0.6 1.4 10.0 3.2 -0.1 -0.0 -0.8 -0.4 -0.3 -0.7 -0.5
Allergy or Eczema 0.1 0.2 0.2 -0.3 0.5 0.1 0.4 0.4 0.5 0.4 -0.4
Cardiovascular Disease 0.1 0.5 1.2 -0.2 -0.9 0.6 -1.1 -0.8 -0.0 -0.4 0.7
Hypothyroidism (self reported) 2.3 5.4 9.7 2.9 -2.1 1.8 -2.2 -2.3 -2.0 -3.1 -1.8
Respiratory disease 0.2 0.3 1.2 -1.1 0.6 -0.5 0.5 0.6 0.5 -0.1 0.2
Type 2 Diabetes (T2D) (2018) 1.2 2.2 3.5 -1.8 1.8 -1.4 1.0 1.8 1.4 1.9 0.4
Lung FEV1/FVC ratio 0.3 1.6 9.1 3.0 -0.1 0.1 -1.0 -0.1 -0.1 0.4 -1.6
Lung FVC 0.7 3.6 6.4 1.4 -1.9 2.4 -2.5 -1.8 -1.8 -0.7 2.0
Neuroticism 0.2 0.6 3.7 0.8 -0.2 0.2 -0.2 -0.1 0.2 -0.1 1.9
Chronotype (morning person) 0.0 0.1 0.3 0.2 0.1 0.1 0.3 0.2 0.0 0.4 0.6
Hair Pigment 0.0 1.1 3.1 -0.1 -0.8 0.3 -1.2 -1.5 -1.2 -1.8 -0.4
Tanning 0.1 1.0 1.7 -0.9 0.8 -1.1 1.0 0.6 1.1 1.3 -1.0
Hand grip strength (left) 0.3 0.7 3.4 -1.8 0.0 -0.6 -0.7 0.2 0.1 0.6 -0.9
Number of treatments/medications taken 0.7 1.3 2.6 -0.9 1.2 -1.1 0.9 1.4 1.2 1.6 -0.1
Average weekly spirits intake 0.8 1.0 3.9 2.0 0.6 -1.0 1.2 0.6 0.8 -0.6 -0.1
Sensitivity / hurt feelings 0.3 0.4 2.0 1.4 0.3 0.2 -0.3 0.3 0.2 0.1 1.1
Frequency of depressed mood in last 2 weeks 0.1 0.2 0.5 0.6 0.5 -0.7 0.4 0.4 0.1 0.4 0.0
Hearing difficulty/problems: Yes 0.7 1.1 4.5 1.6 -0.7 0.4 -0.3 -0.7 0.3 0.8 2.1
Relative age of first facial hair 0.7 1.5 2.7 -0.8 1.2 -1.6 1.2 1.3 1.2 1.4 0.2
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 1.4 -0.0 0.0 -0.0 -0.1 0.4 0.2 0.1 1.2
Ever used hormone-replacement therapy (HRT) 3.4 4.3 7.9 2.8 -2.0 1.8 -2.2 -2.0 -2.1 -1.9 -1.6
Ever had hysterectomy (womb removed) 2.3 2.6 5.5 2.3 -1.5 1.8 -1.5 -1.5 -1.2 -0.8 1.7
Systolic blood pressure, automated reading 0.1 0.2 0.7 -0.9 0.1 -0.4 -0.5 0.3 0.4 -0.4 0.4
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 2.2 -1.5 -0.2 0.3 -0.0 -0.2 0.1 0.3 0.4
Angina 0.1 0.1 0.3 -0.0 -0.3 0.6 0.5 -0.6 -0.1 0.2 0.0
Medication for hormone replacement therapy 0.5 0.5 1.6 1.3 -0.7 0.5 -0.7 -0.6 -0.7 -0.8 -0.2
Vitamin and mineral supplements 3.1 4.2 7.7 -0.7 -2.5 2.4 -1.7 -2.5 -2.1 -2.8 0.4
Supplements: Zinc 2.6 2.9 6.3 -0.7 2.5 -1.1 1.8 2.5 1.9 1.2 -0.7
Medication: Co-codamol 0.6 0.6 3.7 -0.9 -0.3 -0.4 -0.2 -0.2 -0.3 1.9 -0.5
Medication: Metformin 0.6 0.9 1.6 -1.0 1.0 -1.3 -0.1 1.2 0.9 1.1 -0.4
Diabetes (father) 0.3 0.4 0.9 0.4 0.7 -0.8 0.4 0.3 1.0 -0.5 0.7
Diabetes (mother) 0.7 0.9 1.4 0.7 -1.0 0.9 -0.8 -1.2 -0.9 -0.9 -0.9
Severe depression (siblings) 0.6 0.7 3.6 1.9 0.0 -0.3 -0.2 0.0 -0.0 0.5 1.1
Pack years adult smoking proportion 0.3 0.4 1.4 1.1 -0.2 -0.5 -0.3 -0.2 -0.2 1.2 -0.7
Impedance of leg (right) 0.1 0.4 2.0 1.4 -0.5 0.7 0.2 -0.5 -0.2 -0.4 0.1
Leg fat-free mass (left) 0.1 0.5 1.1 -1.1 0.8 -0.9 0.3 0.6 0.6 0.8 -0.3
Trunk fat percentage 1.6 6.5 11.2 -2.3 3.0 -3.2 2.3 2.8 3.3 1.9 -0.3
Hand grip strength (right) 0.4 1.1 3.6 -1.9 0.6 -1.1 -0.5 0.7 0.5 1.2 -1.2
Townsend deprivation index at recruitment 0.1 0.2 0.6 -0.4 0.3 -0.8 0.4 0.3 0.6 -0.0 0.0
Current tobacco smoking 0.4 0.7 4.5 2.1 -0.3 0.2 -0.5 -0.2 -0.3 -0.1 0.7
Average weekly fortified wine intake 0.2 0.3 0.5 -0.1 -0.6 0.3 -0.6 -0.5 -0.2 0.6 0.7
Maternal smoking around birth 0.6 0.8 3.0 -0.9 0.7 -0.8 1.0 0.5 0.4 0.6 -1.7
Fed-up feelings 0.7 1.2 4.8 0.7 0.7 -0.5 0.9 0.8 0.9 1.1 2.2
Frequency of unenthusiasm / disinterest in last 2 weeks 1.2 1.6 2.7 0.1 1.3 -1.6 1.7 1.3 1.3 1.2 0.8
Relative age voice broke 0.3 0.4 1.2 -0.9 -0.8 0.2 -0.5 -0.4 -1.1 -0.2 0.3
Taking other prescription medications 0.4 0.6 1.2 -0.3 0.8 -1.0 0.8 1.1 0.9 0.3 -0.7
Age when periods started (menarche) 0.1 0.2 0.4 -0.2 0.6 -0.5 0.3 0.5 0.4 0.6 -0.5
Bilateral oophorectomy (both ovaries removed) 0.9 1.1 4.6 2.2 -0.5 0.2 -0.4 -0.4 0.0 -0.6 1.7
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 7.0 -0.7 0.2 -0.9 0.8 0.2 0.0 0.7 -2.6
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 0.9 -0.9 0.8 -0.8 0.6 0.7 0.1 0.2 0.7
Qualifications: CSEs or equivalent 0.3 0.3 1.4 0.4 0.5 -0.5 0.5 0.3 0.1 0.5 -1.2
Serious illness, injury or assault to yourself 0.1 0.1 0.3 -0.3 -0.3 0.5 0.2 -0.5 -0.1 0.4 0.5
High blood pressure 0.2 0.4 2.2 0.2 0.0 -0.3 -0.4 0.1 0.7 -0.7 1.5
Hayfever, allergic rhinitis or eczema 0.0 0.1 0.3 -0.6 0.3 0.1 0.1 0.3 0.3 0.4 -0.1
Multivitamins +/- minerals 1.4 1.8 5.4 1.4 1.3 -1.1 1.2 1.2 1.1 2.3 0.6
Stomach or abdominal pain in last month 0.3 0.3 1.8 0.5 -0.3 0.2 -0.4 -0.2 -0.4 -0.4 -1.3
Supplements: Glucosamine 0.2 0.2 0.7 0.0 0.6 -0.4 0.7 0.3 0.8 0.4 0.0
Diverticular disease/diverticulitis (self-reported) 1.2 1.4 4.9 -0.6 1.3 -1.2 0.4 1.1 1.3 -0.3 2.2
Medication: Atenolol 1.3 1.6 2.7 -0.5 -1.6 1.6 -1.1 -1.4 -1.5 0.0 1.4
Medication: Levothyroxine sodium 0.7 1.2 4.6 2.0 -0.5 -0.2 -0.0 -0.5 -0.2 -0.5 -2.1
Sitting height 0.3 2.2 4.8 0.5 -2.2 1.7 -1.1 -2.1 -1.8 -0.9 0.4
Chronic bronchitis/emphysema (father) 0.4 0.5 1.3 -1.1 -0.7 1.0 -0.2 -0.5 -0.6 -0.4 0.3
High blood pressure (mother) 1.2 1.6 7.0 -0.1 -1.4 1.2 -0.8 -1.4 -0.4 0.2 2.6
Body mass index (BMI) 0.5 2.2 3.6 -1.5 1.8 -1.9 1.3 1.6 1.7 0.9 -0.8
Impedance of leg (left) 0.0 0.2 1.0 1.0 -0.3 0.5 0.5 -0.2 0.1 0.0 0.3
Leg predicted mass (left) 0.1 0.6 1.3 -1.1 0.8 -0.9 0.3 0.7 0.6 0.9 -0.4
Trunk fat mass 1.4 5.9 9.5 -2.1 2.9 -3.0 2.3 2.6 3.1 1.9 -0.3
Waist circumference 1.0 3.7 6.3 -1.7 2.4 -2.5 1.2 2.2 2.4 1.6 -0.2
Number of incorrect matches in round 2.2 3.7 5.9 0.6 2.2 -2.4 1.6 1.9 2.3 2.4 0.9
Past tobacco smoking 0.2 0.4 2.9 -1.7 -0.0 0.1 -0.4 0.0 0.0 -0.4 0.1
Alcohol usually taken with meals 0.6 0.9 2.6 -0.3 -1.0 1.6 -0.5 -1.0 -1.0 -1.1 0.2
Nervous feelings 1.6 3.0 6.0 -0.2 1.8 -1.4 2.5 1.7 1.8 2.4 0.6
Frequency of tenseness / restlessness in last 2 weeks 1.5 2.3 6.2 2.5 -1.4 0.9 -0.8 -1.5 -1.4 -1.3 1.6
Hearing difficulty/problems with background noise 0.9 1.4 5.2 2.3 0.9 -0.5 1.0 0.8 0.9 1.3 0.6
Hair/balding pattern: Pattern 2 0.3 0.3 1.3 0.3 -0.5 0.6 0.3 -0.6 -0.4 -0.1 1.1
Had menopause 2.4 3.0 4.7 -0.3 -2.0 2.1 -2.2 -2.0 -2.0 -1.2 -1.2
Had other major operations 1.4 1.8 3.6 -0.9 -1.6 1.5 -1.4 -1.5 -1.9 -0.8 -0.6
Forced vital capacity (FVC) 0.1 0.2 0.9 0.3 0.1 -0.2 -0.1 0.4 0.1 0.9 0.8
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 2.5 -0.4 -0.3 -0.4 0.6 -0.4 -0.2 -0.2 -1.6
Ever unenthusiastic/disinterested for a whole week 1.7 2.1 3.9 -1.5 1.3 -1.4 1.4 1.4 1.0 1.3 -2.0
Qualifications: None of the above 0.3 0.6 0.9 0.3 -0.9 1.0 -1.0 -0.9 -0.6 -0.6 0.9
Financial difficulties in last 2 years 2.2 2.9 4.9 0.6 1.9 -1.4 2.2 2.0 1.7 1.6 1.8
Mouth/teeth dental problems 0.2 0.3 1.2 -1.1 0.5 -0.0 0.2 0.3 0.0 0.8 -0.3
Heart attack 0.3 0.4 2.2 -1.5 0.1 -0.2 0.1 0.5 -0.2 0.4 0.9
Allergy 0.1 0.3 0.6 0.4 -0.8 0.3 -0.7 -0.7 -0.6 -0.5 0.5
Pain all over the body in last month 0.0 0.0 0.2 0.4 0.1 0.1 0.2 0.0 -0.2 -0.2 -0.2
Diabetes (self-reported) 0.5 0.8 1.6 -0.5 1.2 -0.9 0.4 1.2 0.8 1.3 0.3
Hayfever/allergic rhinitis (self-reported) 0.2 0.3 1.6 1.3 0.0 0.5 -0.2 0.0 -0.0 0.3 -0.7
Medication: Ramipril 0.3 0.4 1.2 -0.9 0.4 -0.2 0.3 0.4 0.6 0.1 1.1
Medication: Simvastatin 0.6 0.8 1.6 -0.8 0.9 -1.0 0.0 0.8 1.0 1.3 1.0
Fluid intelligence score 0.9 1.9 3.6 -0.7 -1.5 1.5 -1.6 -1.2 -1.9 -0.5 -1.4
Illnesses of siblings 0.4 0.5 1.4 0.3 -0.9 0.8 -1.2 -0.7 -0.9 -0.2 -0.2
Neuroticism score 0.4 0.8 1.8 0.9 0.6 -0.7 1.0 0.7 0.8 0.8 1.3
Weight 0.3 1.7 3.0 -1.2 1.5 -1.7 1.0 1.3 1.6 1.2 -0.3
Impedance of arm (right) 0.5 2.2 5.2 -0.8 1.7 -1.8 1.1 1.9 2.3 1.0 -0.1
Arm fat percentage (right) 1.8 7.1 11.3 -2.4 3.1 -3.4 2.4 2.9 3.3 1.8 -1.1
Trunk fat-free mass 0.0 0.1 0.4 0.1 0.2 -0.2 0.2 0.1 -0.1 0.5 -0.6
Hip circumference 0.5 2.3 4.8 -0.3 2.0 -2.2 1.1 1.7 2.0 1.2 -0.4
Time employed in main current job 0.7 0.9 1.6 -0.9 1.1 -0.7 0.9 1.2 1.2 0.7 -0.1
Alcohol intake versus 10 years previously 1.6 2.4 9.2 -3.0 1.2 -1.2 1.8 1.1 1.2 0.5 0.8
Father’s age at death 0.4 0.5 2.9 -0.4 0.4 0.1 0.2 0.4 0.3 0.8 1.7
Worrier / anxious feelings 0.9 1.7 2.9 0.8 1.7 -1.4 1.0 1.7 1.6 1.1 0.2
Frequency of tiredness / lethargy in last 2 weeks 0.6 0.9 3.0 -0.3 0.6 -0.1 1.6 0.8 0.9 0.3 1.7
Falls in the last year 1.2 1.7 3.5 0.6 -1.2 1.5 -1.4 -1.2 -1.5 -1.9 0.3
Hair/balding pattern: Pattern 3 0.3 0.4 1.5 -0.4 0.4 -0.7 -0.1 0.5 0.7 -0.5 -1.2
Number of live births 0.5 0.7 2.1 -1.5 -0.8 0.7 -0.9 -0.7 -0.9 0.2 0.0
Forced expiratory volume in 1-second (FEV1) 0.1 0.3 0.9 0.9 -0.5 0.2 -0.9 -0.2 -0.3 0.4 -0.3
Pulse rate 0.2 0.3 0.6 0.8 0.5 -0.8 0.2 0.4 0.5 -0.5 0.2
Happiness 1.0 1.2 2.9 -1.7 0.6 -1.3 0.8 0.6 0.6 1.7 -0.5
Noisy workplace 1.3 1.6 9.4 1.1 -0.2 0.3 0.7 -0.1 1.1 0.2 3.1
Qualifications: A levels/AS levels or equivalent 1.0 2.1 3.7 0.1 1.9 -1.0 1.5 1.9 1.7 1.4 1.4
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.3 0.5 -0.3 0.1 -0.2 -0.3 -0.5 0.2 0.0
Mouth/teeth dental problems: Dentures 0.2 0.3 1.0 0.5 -0.4 0.3 -0.3 -0.1 -0.2 1.0 -0.9
Asthma 0.3 0.7 1.9 -1.0 0.8 -0.3 1.4 0.7 0.6 0.9 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 1.7 1.0 -0.7 1.1 -0.5 -0.9 -0.8 -1.3 1.1
Medication: Cholesterol lowering 0.3 0.4 1.7 -0.4 -0.4 -0.2 -1.3 -0.5 -0.4 0.8 0.2
Depression (self-reported) 0.5 0.6 1.4 0.9 -1.1 0.4 -0.1 -1.2 -1.0 -0.4 -0.2
Medication: Lansoprazole 2.2 2.5 4.7 0.1 -1.7 2.2 -1.5 -1.8 -1.7 -1.8 -0.4
Prospective memory result 0.5 0.7 1.2 1.0 -0.8 0.6 -0.6 -0.8 -0.5 -1.1 0.9
Lung cancer (father) 1.0 1.1 5.1 -0.5 0.4 -0.3 0.5 0.3 0.7 1.6 2.3
Illnesses of mother 1.2 1.5 3.3 -0.8 1.8 -1.4 1.2 1.6 0.9 0.6 -0.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.3 0.9 0.9 -0.5 0.2 -0.9 -0.3 -0.4 0.5 -0.2
Pulse wave Arterial Stiffness index 1.0 1.2 4.8 0.2 0.8 -0.9 0.2 0.9 1.3 0.7 2.2
Impedance of arm (left) 0.5 2.4 4.9 -0.8 1.7 -1.9 1.0 1.9 2.2 1.4 0.6
Arm fat mass (right) 1.2 4.9 7.5 -1.9 2.6 -2.7 2.0 2.4 2.7 1.8 -1.0
Trunk predicted mass 0.0 0.1 0.4 0.1 0.3 -0.3 0.2 0.1 -0.1 0.5 -0.6
Standing height 0.0 0.3 1.2 0.3 -0.2 -0.0 -0.2 -0.1 0.1 1.1 0.8
Length of working week for main job 0.3 0.4 1.1 -0.5 -0.3 0.8 -0.5 -0.3 -1.0 -0.6 -0.6
Exposure to tobacco smoke at home 0.5 0.5 2.8 -1.7 -0.1 -0.5 -0.6 -0.3 0.2 0.2 -0.7
Breastfed as a baby 4.2 5.2 8.4 -1.6 2.4 -2.7 2.6 2.6 2.9 1.5 1.3
Tense / ‘highly strung’ 0.2 0.3 1.2 1.1 0.2 -0.3 0.5 0.4 0.0 -0.5 0.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.3 3.1 -1.2 0.8 -1.8 1.1 0.9 1.1 1.4 -0.6
Hair/balding pattern: Pattern 4 0.1 0.3 1.3 -0.1 0.2 -0.2 1.2 0.1 -0.4 0.5 0.6
Birth weight of first child 2.0 3.6 6.2 -0.6 1.9 -2.0 2.3 1.4 1.8 2.5 2.0
Peak expiratory flow (PEF) 0.1 0.3 0.6 0.4 0.2 -0.5 -0.7 0.3 0.1 0.8 -0.7
Pulse wave reflection index 0.3 0.4 2.3 0.3 0.2 0.3 0.5 0.1 0.2 0.4 1.5
Ever highly irritable/argumentative for 2 days 2.7 3.2 4.8 -1.2 2.0 -1.5 1.9 2.1 1.9 2.2 1.4
Loud music exposure frequency 1.3 1.4 5.6 -0.3 0.4 -1.0 1.5 0.5 0.3 1.3 -2.4
Qualifications: O levels/GCSEs or equivalent 1.4 2.2 4.0 -0.5 1.9 -1.7 1.3 1.9 2.0 1.2 0.4
Mouth/teeth dental problems: Bleeding gums 0.1 0.2 0.5 -0.4 -0.0 -0.7 -0.1 -0.1 -0.3 -0.7 0.3
Blood clot in the leg (DVT) 0.9 1.2 3.1 -0.7 0.9 -1.8 0.9 1.0 1.1 0.3 -1.5
Medication: Paracetamol 1.3 2.2 4.8 0.7 1.4 -1.3 1.3 1.3 1.4 2.2 1.8
Headache pain in last month 1.5 2.6 4.9 -0.2 2.2 -1.4 1.7 2.2 2.1 1.4 0.3
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.7 -0.1 -0.6 1.3 0.1 -0.5 -1.0 -0.9 -0.3
Glaucoma (self-reported) 1.4 1.6 2.6 0.6 -1.1 1.6 -1.4 -1.6 -1.4 -1.5 -0.4
Gout (self-reported) 1.5 2.1 8.4 -1.2 -1.2 1.0 -2.9 -1.0 -1.4 -0.5 -0.9
Hypothyroidism/myxoedema (self-reported) 2.6 5.0 9.6 2.1 -2.2 1.7 -1.7 -2.3 -1.9 -2.5 -3.1
Medication: Amlodipine 2.1 2.9 6.7 -0.4 -2.0 1.8 -2.6 -1.7 -1.6 -1.8 0.7
Medication: Ventolin 100micrograms inhaler 0.6 0.7 1.4 -0.6 1.1 -0.7 1.2 0.8 1.1 0.1 0.6
Birth weight 0.8 1.7 2.8 -1.4 1.3 -1.6 1.4 1.4 1.7 0.9 -0.3
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.2 0.4 -0.1 0.1 0.4 -0.1 0.0 -0.3 -0.4
High blood pressure (siblings) 0.6 0.9 1.2 -1.1 0.9 -0.9 1.0 0.8 1.0 0.5 1.1
Forced vital capacity (FVC), Best measure 0.1 0.2 0.9 0.5 -0.3 -0.1 -0.5 0.0 -0.2 1.0 0.5
Body fat percentage 1.5 6.0 10.0 -2.1 2.9 -3.1 2.3 2.7 3.2 1.7 -0.6
Leg fat percentage (right) 0.8 2.8 4.3 -1.2 2.0 -2.0 1.8 1.7 2.1 0.9 -0.9
Arm fat-free mass (right) 0.0 0.1 0.3 -0.4 0.3 -0.3 0.2 0.1 -0.1 0.6 -0.5
Exposure to tobacco smoke outside home 0.4 0.5 1.0 -1.0 0.9 -0.4 0.9 0.7 0.7 -0.4 0.1
Comparative body size at age 10 0.3 0.7 1.9 -1.4 0.7 -1.0 0.7 0.8 0.3 0.6 -1.0
Number of full brothers 0.5 0.6 1.2 0.5 -0.8 0.9 -0.3 -1.0 -0.9 -1.1 0.1
Worry too long after embarrassment 0.1 0.2 0.6 0.8 -0.3 -0.0 0.1 -0.2 -0.4 0.6 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.9 0.4 -0.1 -0.6 0.8 -0.0 -0.1 1.4 -0.5
Wheeze or whistling in the chest in last year 1.0 1.7 5.0 -1.8 1.3 -1.1 2.2 1.2 0.9 0.4 0.6
Number of children fathered 0.1 0.1 0.2 -0.2 -0.1 0.3 -0.3 0.1 -0.1 -0.5 -0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.3 0.7 -0.3 0.7 -0.6 0.3 0.7 0.8 0.3 0.0
Age at first live birth 1.1 1.9 4.2 -2.0 1.7 -1.4 1.7 1.5 1.1 0.6 0.0
Pulse wave peak to peak time 1.0 1.2 4.3 0.1 -0.9 1.0 -0.3 -1.0 -1.4 -0.8 -2.1
Health satisfaction 2.2 2.9 4.7 -1.0 2.1 -2.2 1.4 1.8 2.1 0.6 1.7
Shortness of breath walking on level ground 1.2 1.4 2.3 -1.3 1.5 -1.4 0.5 1.5 1.5 0.7 -0.3
Qualifications: College or University degree 0.2 0.5 1.5 -0.2 -0.3 0.8 -0.1 -0.1 -0.9 -1.0 -1.2
Eye problems/disorders: None of the above 0.8 0.9 6.5 2.5 -0.3 -0.2 0.4 -0.2 0.1 -0.4 -0.1
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.9 1.0 -0.1 -0.3 -0.3 -0.0 0.1 -1.4 -1.3
Emphysema/chronic bronchitis 0.2 0.2 1.1 -1.1 0.2 -0.3 -0.1 0.4 -0.0 -0.0 -0.0
Medication for pain relief, constipation, heartburn 0.4 0.6 3.0 -0.6 -0.7 0.3 -0.7 -0.5 -0.5 -0.4 -1.7
Neck or shoulder pain in last month 1.2 1.7 4.3 0.1 1.6 -0.5 2.1 1.6 1.9 0.9 -0.1
Medication: Blood pressure 0.3 0.5 1.1 0.6 0.6 -1.1 -0.3 0.6 1.0 0.4 0.5
Angina (self-reported) 0.1 0.1 0.4 -0.1 -0.4 0.6 0.3 -0.6 -0.2 -0.0 0.1
Migraine (self-reported) 0.4 0.5 1.1 0.0 0.8 -0.3 0.3 1.0 0.9 0.9 0.3
Medication: Ibuprofen 0.5 0.6 2.2 0.7 -0.2 0.6 -0.2 -0.5 -0.2 -1.0 1.5
Medication: Allopurinol 0.5 0.7 3.1 -0.8 -0.6 0.4 -1.8 -0.4 -0.6 -0.1 -0.8
Medication: Omeprazole 0.7 0.8 4.8 -0.2 -0.3 -0.0 -1.1 -0.0 -0.4 -0.6 -2.2
Medication: Seretide 50 evohaler 2.8 3.2 4.5 -1.7 1.7 -1.7 2.1 1.6 1.6 1.7 2.0
Mean time to correctly identify matches 1.6 3.0 5.2 1.0 1.9 -2.1 0.4 2.2 2.3 2.3 -0.5
Heart disease (mother) 0.4 0.5 0.9 0.5 0.6 -0.9 -0.2 0.6 0.7 0.8 -0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.6 1.9 3.3 0.9 -1.5 1.8 -0.9 -1.5 -1.4 -1.7 -1.1
Whole body fat mass 1.0 4.4 7.0 -1.8 2.5 -2.6 1.9 2.2 2.6 1.7 -0.6
Leg fat mass (right) 0.7 2.6 4.0 -1.4 1.9 -2.0 1.8 1.6 1.9 1.1 -0.7
Arm predicted mass (right) 0.0 0.1 0.3 -0.2 0.0 0.0 0.2 -0.2 -0.3 0.5 -0.2
Pulse rate, automated reading 0.7 2.2 4.2 -0.9 1.8 -1.5 1.8 1.8 2.1 0.6 0.2
Alcohol intake frequency. 0.4 0.9 2.1 -1.2 -0.7 1.0 -1.1 -0.9 -0.6 -0.5 1.4
Comparative height size at age 10 0.1 0.4 2.1 1.4 -0.1 -0.3 -0.6 -0.0 0.3 0.4 0.5
Number of full sisters 0.5 0.6 2.3 0.0 -0.4 0.2 -1.5 -0.3 -0.7 0.8 -0.9
Suffer from ‘nerves’ 2.0 3.1 7.8 -0.5 1.7 -1.7 2.8 1.7 1.8 1.9 1.1
Overall health rating 1.5 3.3 4.8 -0.8 2.1 -2.0 1.4 2.1 2.2 1.8 1.6
Chest pain or discomfort 3.0 4.3 9.0 0.3 2.3 -2.0 3.0 2.2 3.0 1.3 0.6
Had major operations 2.7 3.2 5.8 -0.5 2.2 -2.0 2.3 2.4 2.1 1.0 0.0
Age at last live birth 0.9 1.2 6.1 -2.5 1.0 -0.3 0.9 0.9 0.8 0.8 0.1
Family relationship satisfaction 0.2 0.2 0.8 -0.3 0.1 -0.1 0.7 0.1 -0.2 0.9 -0.7
Leg pain on walking 5.9 7.4 11.3 -1.8 3.3 -3.2 2.6 3.4 3.0 2.6 0.9
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 0.7 0.1 -0.5 0.4 -0.3 -0.3 -0.8 0.1 0.6
Commuting to job workplace: Car/motor vehicle 0.8 0.9 2.1 -0.4 1.0 -0.7 1.4 1.0 1.0 0.2 -1.0
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 2.6 0.2 -0.6 -0.0 -0.7 -0.7 -0.6 -1.6 -0.6
Medication: Aspirin 1.2 1.5 3.1 0.0 1.2 -1.0 1.7 1.2 1.2 1.5 1.3
Supplements: Vitamin C 1.1 1.3 2.2 0.7 1.4 -1.5 0.6 1.5 1.0 1.4 -0.6
Knee pain experienced in last month 0.3 0.4 0.8 -0.9 0.5 -0.5 0.4 0.5 0.9 0.4 0.8
Hypertension (Self-reported) 0.2 0.4 2.4 0.0 -0.3 -0.0 -0.5 -0.2 0.5 -0.8 1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 1.0 1.0 -0.5 0.5 -0.6 -0.5 -0.4 -0.6 0.7
Illnesses of father: Heart disease 0.5 0.7 1.5 -0.6 -1.2 0.2 -0.8 -1.2 -0.7 -0.8 -0.7
Illnesses of siblings: Diabetes 0.9 1.1 3.0 0.4 1.3 -1.1 1.1 1.0 0.6 0.5 -1.7
Smoking status: Previous 0.3 0.4 1.7 1.3 0.5 -0.7 0.6 0.2 0.2 0.6 -0.5
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.5 0.9 -0.9 0.6 -0.7 0.6 0.8 0.8 0.4 -0.3
Whole body fat-free mass 0.0 0.1 0.3 -0.3 0.3 -0.4 0.2 0.1 -0.0 0.6 -0.5
Leg fat-free mass (right) 0.1 0.5 1.3 -1.1 0.7 -0.8 0.3 0.6 0.5 0.8 -0.1
Arm fat percentage (left) 1.9 7.8 12.8 -2.5 3.3 -3.6 2.4 3.1 3.4 2.0 -0.8
Average weekly red wine intake 0.2 0.3 1.5 1.2 -0.1 0.4 0.1 -0.5 0.1 -0.7 0.2
Handedness (chirality/laterality): Left-handed 1.3 1.6 2.5 0.2 -1.4 1.5 -1.3 -1.4 -1.6 -1.5 -0.3
Mood swings 0.6 1.1 2.4 0.2 1.2 -1.3 1.5 1.3 1.2 -0.1 0.4
Loneliness, isolation 1.6 2.2 3.3 0.4 1.5 -1.7 1.7 1.3 1.8 1.2 1.7
Long-standing illness, disability or infirmity 0.2 0.4 2.2 0.1 0.1 0.1 -0.6 0.5 -0.2 1.5 -0.3
Ever had bowel cancer screening 0.6 0.7 1.5 -0.2 0.7 -0.9 1.2 0.8 1.1 1.1 0.1
Diabetes diagnosed by doctor 0.4 0.6 1.1 -0.9 1.0 -0.8 0.3 1.1 0.7 0.8 0.2
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.8 1.7 -0.1 -0.9 1.0 -1.0 -0.9 -1.0 0.3 1.3
Friendships satisfaction 0.7 0.9 3.8 -1.9 -0.1 0.1 0.0 -0.1 -0.4 1.1 -1.4
Qualifications: nursing, teaching 0.5 0.8 2.0 1.4 -0.7 0.7 -1.2 -0.7 -0.9 0.1 1.0
Commuting to job workplace: Walk 0.6 0.7 1.8 0.1 -1.1 1.4 -0.6 -0.9 -0.9 -0.3 0.7
Eye problems/disorders: Cataract 0.8 0.9 2.7 -1.6 0.7 -0.9 0.1 0.8 0.4 0.8 -1.4
Mouth/teeth dental problems: Mouth ulcers 0.7 1.1 1.8 -1.0 1.2 -1.0 1.0 1.4 1.2 -0.3 -1.0
Medication for cholesterol 0.3 0.4 2.5 0.6 0.3 -0.3 0.0 0.2 -0.1 0.4 -1.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.0 2.4 5.0 0.6 2.2 -1.5 1.5 2.2 1.7 1.4 -0.2
Back pain experienced in last month 0.6 0.8 3.2 0.3 0.5 -0.8 0.9 0.5 1.0 0.7 1.8
Mineral and other dietary supplements 0.1 0.1 0.7 -0.8 -0.3 0.1 -0.1 -0.1 -0.5 -0.2 -0.0
Breast cancer (self-reported) 1.8 2.1 5.2 -0.0 -1.5 1.6 -1.8 -1.2 -1.5 -2.3 -0.0
Asthma (self-reported) 0.4 0.8 2.4 -0.9 1.0 -0.3 1.6 0.9 0.7 1.1 0.2
Osteoporosis (self-reported) 0.7 0.9 1.4 0.8 -1.0 1.2 -1.0 -0.9 -0.8 -0.6 1.2
Osteoarthritis (self-reported) 0.5 0.7 1.9 1.4 -1.1 0.6 -0.3 -0.9 -0.7 0.2 -0.3
Medication: Aspirin 1.1 1.4 2.8 -0.1 1.1 -0.9 1.4 1.0 1.1 1.7 1.6
Medication: Gliclazide 0.6 0.7 4.9 -2.2 0.2 -0.0 -0.2 0.5 0.1 0.4 -0.5
Illnesses of father: None of the above (group 1) 0.3 0.4 1.2 0.1 1.1 -0.2 0.5 1.1 0.6 0.4 -0.2
Smoking status: Current 0.4 0.7 4.9 2.2 0.0 -0.2 -0.2 0.0 0.2 -0.1 0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 1.5 0.2 -0.8 0.4 -1.2 -0.7 -0.5 -0.3 0.7
Whole body water mass 0.1 0.3 0.7 -0.5 0.6 -0.7 0.4 0.4 0.3 0.8 -0.5
Leg predicted mass (right) 0.1 0.4 1.3 -1.2 0.6 -0.8 0.3 0.5 0.5 0.8 -0.1
Arm fat mass (left) 1.2 5.0 7.7 -2.1 2.6 -2.8 2.0 2.4 2.7 1.9 -0.9
Number of self-reported non-cancer illnesses 0.1 0.1 0.5 0.2 0.1 -0.2 0.1 0.2 0.7 0.6 -0.2
Average weekly champagne plus white wine intake 0.4 0.6 3.0 1.2 -0.1 0.1 -0.0 -0.0 -0.3 -0.1 -1.7
Miserableness 1.3 2.2 6.4 -1.7 1.1 -1.2 2.5 1.0 1.4 1.0 1.2
Guilty feelings 0.5 0.8 4.4 2.1 -0.7 0.7 -0.6 -0.6 -0.6 -0.1 0.3
Wears glasses or contact lenses 0.0 0.0 0.1 -0.2 -0.1 -0.2 -0.4 -0.0 0.3 0.2 0.0
Ever taken oral contraceptive pill 1.8 2.0 3.4 0.5 1.8 -1.5 1.3 1.6 1.8 1.7 0.2
Hearing aid user 0.8 0.9 2.4 -1.0 0.6 -0.6 0.9 1.0 1.0 0.7 1.6
Mother’s age at death 0.4 0.5 1.2 1.1 -0.7 1.0 -0.7 -0.4 -0.4 0.1 -0.1
Financial situation satisfaction 0.3 0.4 1.9 -0.8 0.3 -0.3 0.3 0.5 -0.1 -0.6 -1.4
Tinnitus: Yes, now most or all of the time 2.5 2.9 5.4 2.2 -2.2 1.7 -1.1 -2.3 -1.8 -0.6 0.4
Commuting to job workplace: Public transport 0.2 0.3 0.7 0.8 -0.3 -0.3 -0.6 -0.2 -0.1 0.8 -0.5
Eye problems/disorders: Glaucoma 0.7 0.8 1.5 -0.1 -0.6 1.1 -0.9 -1.0 -1.1 -1.2 -0.3
Medication: Blood pressure 0.3 0.6 2.5 -1.0 -0.7 0.5 -0.1 -0.7 -0.2 -0.5 1.6
Pain type(s) experienced in last month: Hip pain 0.5 0.6 2.0 0.7 0.0 -0.8 1.1 0.0 0.5 1.4 0.5
Supplements: Fish oil (including cod liver oil) 0.2 0.3 1.1 1.1 0.2 -0.3 0.3 0.3 0.5 0.9 -0.2
High cholesterol (Self-reported) 0.3 0.5 1.7 -1.3 -0.4 -0.0 -0.9 -0.3 0.1 0.7 0.9
Medication: Bendroflumethiazide 1.3 1.9 3.7 -1.1 -1.9 1.4 -1.1 -1.9 -1.0 -0.2 1.7
Medication: Paracetamol 0.9 1.4 3.3 0.7 1.2 -1.1 1.1 1.1 1.1 1.8 1.0
Medication: Lisinopril 0.4 0.5 1.3 0.5 -0.6 0.5 -1.1 -0.8 -0.2 -0.7 -0.8
Medication: Atorvastatin 1.4 1.8 3.4 -0.0 -1.5 1.5 -1.4 -1.3 -1.9 -1.1 -1.2
Illnesses of father: High blood pressure 0.3 0.4 1.4 1.2 -0.1 -0.7 -0.7 0.0 0.1 1.0 0.3
Alcohol drinker status: Never 1.9 2.3 3.5 -1.9 -1.7 1.8 -1.5 -1.7 -1.6 -1.2 0.0
Ever smoked 0.2 0.4 2.4 1.6 -0.3 0.3 -0.0 -0.1 -0.4 -0.1 -0.3
Basal metabolic rate 0.1 0.4 0.7 -0.5 0.7 -0.8 0.5 0.6 0.5 0.8 -0.5
Leg fat percentage (left) 0.9 3.3 5.2 -1.4 2.2 -2.2 1.9 2.0 2.3 1.2 -0.8
Arm fat-free mass (left) 0.0 0.2 0.7 -0.1 -0.2 0.3 -0.2 -0.4 -0.4 0.3 -0.8
Number of operations (self-reported) 0.3 0.4 1.1 -0.5 -0.6 0.6 -0.5 -0.4 -0.9 1.1 0.3
Average weekly beer plus cider intake 1.2 1.7 3.2 -0.5 1.5 -1.5 1.0 1.8 1.8 0.9 -0.9
Irritability 0.2 0.3 1.6 0.3 -0.0 0.1 0.5 0.2 -0.1 0.6 1.3
Risk taking 0.1 0.2 0.6 0.8 0.3 0.1 0.2 0.2 0.1 -0.3 0.7
Ever had prostate specific antigen (PSA) test 2.2 2.6 7.8 -0.2 1.6 -1.6 1.6 1.7 1.4 2.8 -0.7
Fractured/broken bones in last 5 years 0.6 0.8 4.7 0.3 0.3 -0.3 0.7 0.2 1.0 -0.2 2.2
Age started oral contraceptive pill 0.8 0.9 1.9 0.4 -1.2 1.4 -1.2 -1.2 -1.0 -0.4 -0.2
Diastolic blood pressure, automated reading 0.3 0.8 1.2 -0.8 1.0 -1.1 0.5 0.9 1.1 -0.5 1.0
Ever depressed for a whole week 0.2 0.2 0.8 -0.1 -0.5 -0.1 -0.9 -0.3 -0.5 0.3 -0.6
Unable to work because of sickness or disability 0.4 0.5 1.0 -0.9 0.3 -0.6 -0.3 0.6 -0.6 0.8 -1.0
Commuting to job workplace: Cycle 0.8 1.0 2.0 1.4 -1.2 0.7 -1.1 -1.1 -1.2 -0.4 0.1
Myopia 1.6 2.3 4.2 0.3 1.5 -1.7 2.0 1.4 1.6 1.8 -1.1
Vascular/heart problems diagnosed by doctor 0.3 0.7 1.6 0.1 0.8 -0.6 1.3 0.7 0.4 1.0 -1.2
Cholesterol lowering medication 0.6 0.9 4.8 -2.2 0.6 -0.7 0.2 0.7 0.6 -0.0 -0.5
Medication: Omeprazole (e.g. Zanprol) 0.9 1.1 6.1 -0.1 -0.6 0.2 -1.0 -0.2 -0.5 -1.1 -2.5
Pain experienced in last month 0.6 1.1 2.5 0.6 -1.2 0.8 -1.2 -0.9 -1.6 -0.7 -0.7
Supplements: Calcium 0.2 0.3 0.7 0.5 0.4 -0.2 0.1 0.2 0.3 0.8 0.8
Basal cell carcinoma (self-reported) 1.0 1.1 5.4 -0.9 0.6 -0.8 1.0 0.7 0.7 2.3 -0.0
Heart attack/myocardial infarction (self-reported) 0.3 0.4 1.9 -1.4 0.0 -0.1 0.1 0.4 -0.3 0.3 1.0
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 2.7 -0.3 0.4 -1.2 0.3 0.4 0.6 -0.1 -1.6
Heart disease (siblings) 2.4 3.0 5.5 -0.8 1.7 -1.9 2.0 1.7 2.4 1.7 1.1
Alcohol drinker status: Previous 1.7 1.9 9.7 1.6 -0.9 0.6 -1.1 -0.9 -0.6 0.2 3.1
Pack years of smoking 0.2 0.3 1.3 0.8 -0.2 -0.5 -0.5 -0.3 -0.1 1.1 0.0
Impedance of whole body 0.2 0.9 2.3 0.0 1.0 -0.9 0.9 1.1 1.5 0.7 0.6
Leg fat mass (left) 0.6 2.2 3.4 -1.4 1.7 -1.8 1.6 1.5 1.8 1.1 -0.6
Arm predicted mass (left) 0.0 0.1 0.7 -0.1 0.2 -0.0 0.2 0.0 -0.1 0.5 -0.8