Best TWAS P=1.79e-08 · Best GWAS P=4.1e-08 conditioned to 0.00421
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | IMPA1 | 0.16 | 0.10 | lasso | 5 | 0.18 | 2.3e-14 | -5.2 | 5.3 | 8.6e-08 | -0.57 | 0.04 | 0.96 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | IMPA1 | 0.18 | 0.08 | lasso | 3 | 0.11 | 4.5e-09 | -5.2 | 5.2 | 2.3e-07 | -0.51 | 0.03 | 0.97 | FALSE |
| 3 | GTEx | Stomach | IMPA1 | 0.09 | 0.01 | enet | 5 | 0.04 | 6.2e-03 | -4.4 | 5.6 | 1.8e-08 | -0.55 | 0.08 | 0.78 | TRUE |