[Hub]/) : Traits : Blood Platelet Count : ← →

chr8:65,812,899-67,382,535

Best TWAS P=1.06e-14 · Best GWAS P=6.48e-22 conditioned to 5.08e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MTFR1 0.07 0.04 lasso 6 0.04 1.6e-05 -4.4 6.0 1.5e-09 -0.49 0.26 0.56 FALSE
2 GTEx Adipose Subcutaneous ARMC1 0.04 0.04 lasso 2 0.03 2.1e-03 -3.8 -5.6 2.6e-08 0.45 0.54 0.03 FALSE
3 GTEx Brain Caudate basal ganglia CTD-3025N20.3 0.28 0.24 lasso 3 0.26 3.2e-08 -3.8 5.4 5.7e-08 -0.45 0.96 0.02 FALSE
4 GTEx Cells Transformed fibroblasts CTD-3025N20.3 0.19 0.14 enet 26 0.13 9.7e-10 -3.8 6.4 2.0e-10 -0.52 1.00 0.00 FALSE
5 GTEx Colon Transverse MTFR1 0.13 0.01 lasso 7 0.04 6.5e-03 -5.1 -5.1 2.9e-07 0.54 0.27 0.04 FALSE
6 YFS Blood ARMC1 0.03 0.01 lasso 7 0.02 1.5e-06 -7.1 -5.3 1.2e-07 0.42 0.71 0.10 FALSE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma MTFR1 0.05 0.01 blup 59 0.03 9.5e-03 -7.1 -5.9 3.0e-09 0.50 0.01 0.83 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MTFR1 0.10 0.06 lasso 8 0.06 3.9e-07 -5.6 -5.3 9.2e-08 0.47 0.91 0.07 FALSE
9 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma MTFR1 0.05 0.02 blup 58 0.02 2.2e-02 -7.2 -6.4 1.8e-10 0.53 0.01 0.96 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma MTFR1 0.06 0.03 blup 60 0.05 3.8e-04 -4.2 -5.7 1.4e-08 0.48 0.02 0.96 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors ARMC1 0.24 0.14 lasso 8 0.17 1.7e-06 -7.2 -6.4 1.3e-10 0.51 0.00 0.99 FALSE
12 The Cancer Genome Atlas Testicular Germ Cell Tumors MTFR1 0.20 0.03 blup 60 0.04 1.4e-02 -7.1 -6.4 1.9e-10 0.54 0.01 0.74 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma PDE7A 0.03 0.00 blup 66 0.01 1.9e-02 -7.1 -7.7 1.1e-14 0.72 0.01 0.79 TRUE