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chr8:65,812,899-67,382,535

Best TWAS P=1.06e-14 · Best GWAS P=6.48e-22 conditioned to 5.08e-09

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	The Cancer Genome Atlas	Thyroid Carcinoma	PDE7A	0.03	0.00	blup	66	0.01	1.9e-02	-7.1	-7.7	1.1e-14	0.72	0.01	0.79	TRUE
11	The Cancer Genome Atlas	Testicular Germ Cell Tumors	ARMC1	0.24	0.14	lasso	8	0.17	1.7e-06	-7.2	-6.4	1.3e-10	0.51	0.00	0.99	FALSE
9	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	MTFR1	0.05	0.02	blup	58	0.02	2.2e-02	-7.2	-6.4	1.8e-10	0.53	0.01	0.96	FALSE
12	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MTFR1	0.20	0.03	blup	60	0.04	1.4e-02	-7.1	-6.4	1.9e-10	0.54	0.01	0.74	FALSE
4	GTEx	Cells Transformed fibroblasts	CTD-3025N20.3	0.19	0.14	enet	26	0.13	9.7e-10	-3.8	6.4	2.0e-10	-0.52	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	MTFR1	0.07	0.04	lasso	6	0.04	1.6e-05	-4.4	6.0	1.5e-09	-0.49	0.26	0.56	FALSE
7	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	MTFR1	0.05	0.01	blup	59	0.03	9.5e-03	-7.1	-5.9	3.0e-09	0.50	0.01	0.83	FALSE
10	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MTFR1	0.06	0.03	blup	60	0.05	3.8e-04	-4.2	-5.7	1.4e-08	0.48	0.02	0.96	FALSE
2	GTEx	Adipose Subcutaneous	ARMC1	0.04	0.04	lasso	2	0.03	2.1e-03	-3.8	-5.6	2.6e-08	0.45	0.54	0.03	FALSE
3	GTEx	Brain Caudate basal ganglia	CTD-3025N20.3	0.28	0.24	lasso	3	0.26	3.2e-08	-3.8	5.4	5.7e-08	-0.45	0.96	0.02	FALSE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MTFR1	0.10	0.06	lasso	8	0.06	3.9e-07	-5.6	-5.3	9.2e-08	0.47	0.91	0.07	FALSE
6	YFS	Blood	ARMC1	0.03	0.01	lasso	7	0.02	1.5e-06	-7.1	-5.3	1.2e-07	0.42	0.71	0.10	FALSE
5	GTEx	Colon Transverse	MTFR1	0.13	0.01	lasso	7	0.04	6.5e-03	-5.1	-5.1	2.9e-07	0.54	0.27	0.04	FALSE