Best TWAS P=3.45e-13 · Best GWAS P=1.37e-14 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RRM2B | 0.14 | 0.05 | lasso | 3 | 0.04 | 2.0e-04 | 5.8 | 6.1 | 1.0e-09 | 0.78 | 0.09 | 0.82 | FALSE |
| 2 | GTEx | Nerve Tibial | RRM2B | 0.17 | 0.18 | lasso | 1 | 0.18 | 1.7e-12 | 7.3 | 7.3 | 3.4e-13 | 0.98 | 0.02 | 0.98 | TRUE |
| 3 | YFS | Blood | UBR5 | 0.07 | 0.03 | bslmm | 531 | 0.03 | 9.3e-11 | 7.3 | 6.8 | 8.0e-12 | 0.81 | 0.00 | 1.00 | FALSE |