TWAS hub - RRM2B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.138	0.0460	7.3e-04	0.055	NA	0.012	NA	0.043	2.8e-05	NA	3.5e-02	NA	2.0e-04
2	GTEx	Artery Aorta	0.123	0.0500	9.5e-03	0.060	NA	0.022	NA	0.019	3.2e-04	NA	2.1e-02	NA	3.0e-02
3	GTEx	Artery Tibial	0.262	0.0568	5.8e-08	0.152	NA	0.158	NA	0.162	5.5e-12	NA	2.2e-12	NA	1.1e-12
4	GTEx	Colon Transverse	0.158	0.0590	7.5e-03	0.029	NA	0.103	NA	0.042	1.6e-02	NA	1.3e-05	NA	4.4e-03
5	GTEx	Esophagus Mucosa	0.156	0.0490	5.1e-04	0.031	NA	0.037	NA	0.052	3.8e-03	NA	1.6e-03	NA	2.2e-04
6	GTEx	Nerve Tibial	0.167	0.0487	5.6e-04	0.183	NA	0.163	NA	0.176	5.7e-13	NA	1.2e-11	NA	1.7e-12
7	GTEx	Testis	0.297	0.0700	9.6e-06	0.161	NA	0.203	NA	0.061	1.2e-07	NA	2.1e-09	NA	1.1e-03
8	YFS	Blood	0.216	0.0283	0.0e+00	0.208	0.200	0.219	0.22	0.217	4.3e-66	1.7e-63	4.3e-70	3.7e-70	2.1e-69
9	TCGA	Cervical Squamous Cell Carcinoma	0.139	0.0570	1.5e-03	0.018	0.018	0.026	NA	0.016	4.4e-02	4.1e-02	1.9e-02	NA	5.3e-02
10	TCGA	Pheochromocytoma and Paraganglioma	0.157	0.0730	1.1e-03	0.046	0.097	0.040	NA	0.060	6.7e-03	1.1e-04	1.0e-02	NA	2.1e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Chest pain or discomfort	5.3	7.6	15.5	-2.7	-3.1	-3.5	-2.4	3.9	-1.7	0.5	2.7	2.2	-3.3
Long-standing illness, disability or infirmity	5.3	8.2	16.0	-3.8	-3.0	-3.5	-2.2	3.0	-1.3	1.7	2.8	1.8	-4.0
Unable to work because of sickness or disability	3.7	4.8	11.0	-1.6	-3.0	-2.7	-0.8	3.3	-1.1	1.2	2.3	1.0	-3.0
Angina (self-reported)	3.4	4.5	8.8	-1.5	-2.8	-3.0	-1.8	2.9	-0.4	-0.2	2.6	1.3	-2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.4	4.0	7.8	1.3	1.9	2.4	-1.2	-2.3	-0.7	-2.4	-2.8	-1.1	2.6
Breastfed as a baby	3.3	4.1	9.2	-0.7	-2.0	-2.9	-0.6	2.0	0.4	1.3	2.6	3.0	-2.5
Eye problems/disorders: None of the above	3.1	3.6	8.9	0.8	3.0	2.4	0.2	-1.1	-0.4	-1.2	-2.7	-1.7	2.7
Neuroticism (2016)	2.8	4.0	9.5	-3.1	-1.7	-2.5	-2.0	1.3	-1.9	1.2	1.6	1.1	-2.6
Loud music exposure frequency	2.8	3.0	9.2	3.0	0.4	1.6	1.0	-1.5	1.4	-2.0	-1.4	-1.6	2.1
Relative age of first facial hair	2.7	5.6	12.9	2.3	3.6	2.8	0.1	-2.3	0.5	-0.8	-2.5	-2.7	3.2
Number of children fathered	2.7	3.1	7.3	-1.1	-2.7	-2.3	-0.9	2.1	-0.3	-1.3	1.6	2.2	-1.7
Angina	2.6	3.5	7.8	-1.1	-2.5	-2.5	-1.9	2.8	-0.1	-0.6	2.2	0.9	-1.9
Fractured/broken bones in last 5 years	2.6	3.3	6.3	0.1	-2.2	-2.1	1.2	2.1	1.6	-0.4	2.4	2.5	-1.9
Deep venous thrombosis (DVT) (self-reported)	2.6	3.3	9.8	-2.6	-1.3	-1.4	-2.0	-0.1	-3.1	2.1	0.8	0.5	-1.9
Blood Red Count	2.5	24.5	43.6	-3.8	-6.5	-6.6	-2.7	4.2	-1.1	5.3	6.6	2.0	-6.5
Ever unenthusiastic/disinterested for a whole week	2.5	3.0	10.6	0.3	1.4	2.3	-0.5	-3.3	-1.2	1.3	-2.0	-1.8	1.3
Hearing difficulty/problems: Yes	2.4	3.7	7.0	-1.4	-2.6	-2.4	-1.8	2.6	0.2	0.1	2.3	1.4	-2.2
Mouth/teeth dental problems	2.4	3.7	9.4	1.7	2.3	2.7	1.5	-3.1	0.3	0.2	-1.9	-1.2	2.2
Medication: Ramipril	2.3	3.0	5.4	-1.4	-1.5	-2.2	-0.3	1.7	-0.3	1.5	2.1	2.2	-2.3
Exposure to tobacco smoke at home	2.1	2.3	5.2	2.3	1.6	1.3	2.1	-1.4	1.9	-1.0	-0.5	-0.5	1.5
Hair/balding pattern: Pattern 4	2.1	5.1	7.5	-2.6	-2.5	-2.7	-2.7	2.1	-0.7	1.4	2.1	2.5	-2.5
Blood clot in the leg (DVT)	2.1	2.7	7.7	-2.5	-1.3	-1.4	-1.6	0.2	-2.8	1.7	0.8	0.7	-1.9
Emphysema/chronic bronchitis	2.1	2.4	9.2	-3.0	0.4	-0.0	-2.1	0.6	-2.8	-0.8	-0.6	0.6	-0.7
Heart attack/myocardial infarction (self-reported)	2.1	2.6	4.9	-1.1	-1.7	-2.1	-1.2	1.5	-0.2	1.6	1.9	2.2	-1.8
Relative age voice broke	2.0	3.1	7.7	0.7	2.8	2.1	-1.0	-1.4	-1.5	-0.7	-2.1	-1.4	2.4
Number of incorrect matches in round	2.0	3.4	8.5	-2.9	-1.6	-2.1	-0.3	2.8	-1.3	0.5	1.4	1.3	-2.2
Overall health rating	2.0	4.3	14.7	-3.8	-0.5	-1.1	-3.3	2.4	-2.7	-0.0	0.1	-0.7	-1.5
Osteoporosis (self-reported)	2.0	2.5	5.1	0.1	-1.9	-2.0	0.9	1.8	0.9	-0.7	2.3	2.1	-1.5
Heart attack	1.9	2.5	5.0	-1.0	-1.5	-1.9	-1.2	1.4	-0.3	1.7	1.8	2.2	-1.7
Qualifications: O levels/GCSEs or equivalent	1.9	3.0	6.9	1.8	2.3	2.0	1.9	-2.6	0.8	-0.8	-1.6	-0.4	1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	5.9	-1.4	-1.8	-1.6	-0.9	2.4	-0.8	0.3	1.2	2.2	-1.9
Diverticular disease/diverticulitis (self-reported)	1.8	2.1	4.9	0.7	1.7	2.2	-1.0	-0.9	0.4	-0.9	-2.1	-1.8	1.5
Medication: Atenolol	1.8	2.2	10.0	-2.3	0.5	-1.0	-3.2	0.6	-1.5	-0.3	0.7	1.6	-0.5
Had other major operations	1.8	2.2	5.4	0.3	1.1	1.6	-2.1	0.2	-0.0	-2.3	-1.8	-2.0	0.9
Mouth/teeth dental problems: Dentures	1.8	3.0	8.8	-2.3	-1.1	-1.8	-2.8	3.0	-1.0	-0.2	1.3	0.4	-1.0
Medication: Lansoprazole	1.8	2.0	7.3	-2.0	0.5	0.1	-2.7	1.2	-2.6	0.2	-0.7	0.2	-0.4
Illnesses of siblings: Diabetes	1.8	2.2	5.3	-0.0	-2.3	-1.6	-0.6	1.5	2.0	0.8	2.0	-0.1	-1.5
Medication: Gliclazide	1.8	2.0	5.3	-2.0	-1.1	-1.4	-1.0	2.3	-1.2	-0.8	0.9	1.4	-1.5
Qualifications: A levels/AS levels or equivalent	1.7	3.8	11.7	3.4	2.2	1.3	2.2	-1.7	2.9	-0.8	-0.8	0.0	1.6
Eye problems/disorders: Cataract	1.7	2.0	4.7	0.2	-2.2	-1.8	1.6	0.3	0.8	-0.3	2.0	1.6	-1.5
Chronotype (morning person)	1.6	3.7	16.3	-2.7	1.1	1.1	-0.4	-1.2	-4.0	2.1	-1.3	-1.7	-0.1
High blood pressure (mother)	1.6	2.2	3.8	1.7	-1.0	-1.3	1.2	-0.0	1.9	1.9	1.8	1.6	-1.3
Glaucoma (self-reported)	1.6	1.9	5.0	-0.7	-0.1	-1.5	-2.2	2.0	1.0	0.8	1.4	1.1	-1.4
Mean time to correctly identify matches	1.6	3.0	11.5	-3.4	0.8	-0.1	-1.9	0.9	-2.9	1.8	-0.9	-0.7	-0.5
Heart disease (mother)	1.6	1.9	6.8	1.9	-1.9	-0.9	0.9	0.0	2.6	0.4	1.8	0.4	-0.4
Bipolar Disorder (2011)	1.5	1.4	4.1	-1.1	0.3	0.6	-0.9	-1.4	-2.0	1.3	-1.2	-1.4	0.6
Medication for hormone replacement therapy	1.5	1.6	5.2	2.3	0.8	0.5	0.2	-2.3	1.2	1.9	0.5	-0.1	0.4
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	5.3	0.0	1.4	2.3	-0.3	-1.9	-1.5	-0.2	-2.3	-1.8	1.1
Wheeze or whistling in the chest in last year	1.5	2.7	6.0	-2.4	0.2	-1.4	-2.0	2.5	-1.7	-0.4	0.7	2.1	-1.3
Breast cancer (self-reported)	1.5	1.7	4.3	1.4	0.6	1.4	2.1	-1.1	0.4	-1.5	-1.4	-1.5	1.0
Eye problems/disorders: Glaucoma	1.5	1.8	3.8	-0.8	-0.2	-1.5	-1.9	0.8	0.4	2.0	1.4	1.5	-1.5
Depression (Nagel 2018)	1.4	2.1	6.9	-2.0	-1.0	-0.9	-1.6	1.0	-2.6	1.5	0.5	-0.1	-1.5
Alzheimer’s Disease (in father)	1.4	1.5	6.1	-1.3	1.2	0.3	-0.9	-1.3	-2.5	1.8	-0.3	0.1	-0.2
Hand grip strength (left)	1.4	3.7	8.6	2.3	2.3	2.2	1.5	-2.9	0.5	-1.3	-2.0	-0.6	2.3
Hand grip strength (right)	1.4	3.7	7.1	2.0	2.3	2.4	1.9	-2.7	-0.0	-1.3	-2.1	-1.1	2.2
Hypothyroidism/myxoedema (self-reported)	1.4	2.8	7.6	-1.9	1.2	2.0	-0.8	-0.6	-2.8	-1.0	-2.3	-1.6	1.3
Comparative body size at age 10	1.4	3.7	7.8	-1.2	-2.3	-2.7	-0.7	0.9	-0.4	0.5	2.8	2.6	-2.7
Prostate Cancer	1.3	1.8	3.2	1.6	1.1	1.6	1.8	-1.4	0.7	-0.6	-1.1	-1.6	1.4
Taking other prescription medications	1.3	2.1	6.4	-2.5	-0.2	-0.6	-2.2	1.8	-1.5	-0.4	-0.2	1.0	-1.4
Qualifications: CSEs or equivalent	1.3	1.7	6.0	-0.6	-1.6	-1.3	-2.4	1.4	-0.5	-0.5	0.9	1.4	-1.1
Medication: Levothyroxine sodium	1.3	2.2	5.4	-1.5	1.8	1.7	0.0	-0.1	-2.3	-1.2	-2.1	-0.9	1.3
Illnesses of mother	1.3	1.6	4.0	-0.6	1.3	1.7	-0.6	-0.7	-0.9	-2.0	-2.0	-1.1	1.0
Mouth/teeth dental problems: Loose teeth	1.3	1.5	4.2	-2.0	-1.1	-1.5	-0.7	1.7	-0.8	-0.3	1.1	1.3	-1.0
Alcohol intake frequency.	1.3	3.0	9.9	-2.0	1.0	1.2	-3.1	0.5	-2.1	-1.5	-2.0	-1.3	1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	3.1	0.4	1.4	1.6	-0.7	-0.6	0.9	-1.3	-1.4	-1.0	1.8
Mother’s age at death	1.3	1.6	5.0	1.0	2.2	1.4	-0.2	-2.1	-0.1	-0.7	-1.2	0.4	1.3
Neuroticism (Nagel 2018)	1.2	2.8	12.2	-1.8	-0.8	-1.4	-3.5	1.7	-1.7	0.4	0.7	0.7	-1.8
Alzheimer’s Disease (including proxy)	1.2	1.8	5.5	-2.0	-0.9	-0.9	-2.3	-0.1	-1.9	1.2	0.3	0.1	-1.3
Ulcerative Colitis (UC)	1.2	2.3	4.8	0.3	-0.8	-1.7	1.0	1.9	2.1	-0.2	2.2	1.9	-1.3
Major Depression (MDD)	1.2	1.5	3.9	-1.8	-0.6	-0.9	-1.6	2.0	-1.7	-0.9	0.2	-0.5	-0.3
Age at First Birth	1.2	1.8	5.8	0.6	2.0	0.9	1.9	-2.4	1.1	1.4	-0.4	0.5	-0.1
Triglycerides	1.2	1.9	4.2	-0.8	-1.7	-1.8	1.0	0.3	-0.2	2.1	2.0	0.7	-1.7
Allergy	1.2	2.8	15.2	3.1	-0.7	-0.2	1.0	-0.1	3.9	-0.7	0.9	-0.0	0.7
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	6.6	-2.1	0.6	0.2	-1.3	-0.7	-2.6	1.2	-0.7	-0.6	0.2
Number of full brothers	1.2	1.5	6.7	-0.7	0.3	0.4	-0.5	2.1	0.3	-2.6	-0.9	-0.6	1.1
Pulse rate, automated reading	1.2	3.7	12.5	-3.5	-1.1	-1.6	-1.0	0.7	-3.3	1.8	0.7	1.1	-2.1
Commuting to job workplace: Car/motor vehicle	1.2	1.3	2.8	0.6	0.7	0.9	-0.8	-1.7	-1.4	-0.9	-1.0	-1.4	1.6
Loneliness, isolation	1.2	1.6	4.3	-1.6	-0.8	-0.6	-2.1	1.8	-1.6	0.6	0.4	-0.4	-1.3
Ever had bowel cancer screening	1.2	1.3	4.0	0.3	-1.0	-0.1	-1.1	1.8	0.3	-1.8	-0.3	-2.0	0.6
Financial situation satisfaction	1.2	1.4	4.0	1.5	0.9	1.3	2.0	-1.1	1.3	-0.4	-0.5	-0.9	1.2
Heart disease (siblings)	1.2	1.5	4.1	-2.0	-0.5	-1.4	-1.6	1.5	-0.5	1.4	1.0	0.1	-0.9
Depressed Affect (Nagel 2018)	1.1	2.4	9.4	-1.9	-0.8	-1.3	-3.1	1.7	-1.7	0.1	0.6	0.3	-1.5
Schizophrenia vs Biploar Disorder	1.1	1.5	3.3	-1.1	-1.3	-1.4	-0.2	1.4	-1.0	0.8	1.4	1.0	-1.8
Coronary Artery Disease (CAD)	1.1	1.3	4.1	-1.5	-1.6	-1.1	0.7	0.1	-0.9	2.0	0.8	-0.4	-0.8
Hypothyroidism (self reported)	1.1	2.4	9.0	-1.8	0.4	1.7	-0.7	-0.8	-3.0	0.3	-1.9	-1.8	1.0
Sensitivity / hurt feelings	1.1	1.8	4.9	-1.9	-1.2	-1.0	-2.2	1.9	-1.5	-0.5	0.1	-0.4	-1.0
Maternal smoking around birth	1.1	1.5	3.4	-1.6	0.8	0.8	-1.8	0.9	-1.8	-0.8	-1.4	-0.4	1.0
Time employed in main current job	1.1	1.3	4.4	-1.4	1.1	0.6	-1.8	-0.1	-2.1	0.0	-1.0	0.1	1.0
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	6.1	2.5	0.0	0.1	0.4	-0.7	2.5	-0.0	0.3	-0.2	0.4
Peak expiratory flow (PEF)	1.1	2.6	8.2	2.9	0.4	1.1	2.2	-1.6	2.4	-0.9	-0.6	-0.4	1.5
Average weekly beer plus cider intake	1.1	1.7	7.6	1.1	-0.2	-0.7	1.6	0.5	2.8	1.3	1.2	0.8	-0.8
Age started oral contraceptive pill	1.1	1.4	3.0	-1.0	-1.2	-1.4	-0.8	1.4	-0.3	0.9	1.1	1.4	-1.7
Ever depressed for a whole week	1.1	1.4	3.3	-1.1	0.2	1.0	-1.5	-1.8	-1.2	1.5	-1.0	-1.1	-0.4
Reaction Time	1.0	1.9	8.1	-2.8	-0.1	-0.6	-0.8	1.2	-2.1	1.6	-0.2	-0.4	-1.1
Blood Platelet Count	1.0	11.5	53.0	6.1	-0.4	-0.5	3.5	-0.9	7.3	0.5	2.2	2.4	0.2
Blood White Count	1.0	7.4	18.7	-1.9	-2.2	-3.0	-3.0	1.6	-0.6	4.3	3.4	0.7	-3.9
Diabetes (father)	1.0	1.2	4.7	2.2	-0.5	0.5	1.6	-0.7	0.9	1.3	0.4	-1.1	0.1
Supplements: Glucosamine	1.0	1.3	3.8	1.2	-1.4	0.2	0.6	1.0	1.9	-1.4	-0.0	-1.4	-0.5
Pain all over the body in last month	1.0	1.1	1.7	-1.1	-1.1	-1.1	1.1	1.0	-0.3	-0.2	1.3	1.2	-1.3
Neuroticism score	1.0	2.0	9.8	-1.4	-0.7	-0.8	-3.1	1.7	-1.6	-0.2	0.3	0.5	-1.1
Falls in the last year	1.0	1.3	2.3	0.5	-1.4	-1.0	-0.4	1.5	1.1	-1.5	1.5	1.2	-0.4
High blood pressure (siblings)	1.0	1.4	3.2	-0.2	-1.4	-1.5	-0.6	1.8	0.6	0.5	1.6	1.3	-1.2
Migraine (self-reported)	1.0	1.2	3.3	1.4	0.8	-0.3	-0.9	0.4	1.8	-1.4	-0.1	1.3	1.0
Handedness (chirality/laterality): Left-handed	1.0	1.2	5.3	-1.1	-0.8	-1.4	-0.4	2.3	-1.1	-0.7	0.8	0.4	0.3
Osteoarthritis (self-reported)	1.0	1.4	4.6	-2.1	-0.1	-0.4	-1.3	0.7	-1.8	-0.3	-0.5	0.8	-1.5
Miserableness	1.0	1.7	5.1	-2.2	-0.2	0.2	-2.2	1.0	-2.3	-1.0	-0.6	-0.2	-0.4
Guilty feelings	1.0	1.5	6.0	-1.9	-0.1	-0.2	-1.8	0.5	-2.4	0.5	-0.4	0.7	-1.2
Illnesses of father: High blood pressure	1.0	1.2	3.0	1.0	-1.7	-1.2	1.0	1.0	1.3	-0.8	1.3	0.2	-0.6
Irritability	1.0	1.7	5.5	-0.9	0.0	-1.4	-2.3	2.3	-0.7	0.3	1.0	0.9	-0.9
Basal cell carcinoma (self-reported)	1.0	1.1	5.3	0.9	0.8	1.1	2.3	-1.0	0.7	1.1	-0.4	-0.5	0.6
Breast Cancer	0.9	2.3	9.3	-0.4	-3.0	-1.6	-1.6	1.7	-0.4	0.1	1.6	-0.2	-1.5
Respiratory disease	0.9	2.0	6.6	-2.6	1.1	-0.1	-1.4	1.1	-2.2	0.1	-0.8	1.4	-1.1
Medication: Metformin	0.9	1.3	2.8	-0.5	-1.5	-1.7	-1.3	1.5	0.2	0.3	1.4	-0.1	-1.0
Severe depression (siblings)	0.9	1.1	2.6	-1.0	-0.9	-1.5	-0.2	0.9	0.1	1.6	1.2	0.2	-1.2
Age when periods started (menarche)	0.9	2.1	5.7	0.9	0.9	1.4	-0.7	-0.9	-0.9	-1.5	-1.6	-2.4	2.3
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	2.4	0.4	1.5	1.3	-0.3	-0.4	0.4	-0.8	-1.2	-1.4	1.3
Hearing difficulty/problems with background noise	0.9	1.4	11.0	-0.8	0.0	-0.6	-3.3	1.2	-0.3	-0.8	0.3	-0.1	-0.2
Medication: Simvastatin	0.9	1.3	4.8	-0.3	-1.0	-1.2	-1.2	2.2	0.7	0.3	1.3	0.2	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	4.7	-1.4	-0.6	0.3	-2.0	0.2	-2.2	-0.1	-0.7	-1.6	-0.5
Pulse rate	0.9	1.5	4.3	-2.1	-0.8	-1.3	-0.7	-0.0	-1.7	1.3	1.2	0.2	-1.1
Chronic bronchitis/emphysema (mother)	0.9	1.1	6.5	-0.4	2.5	1.0	-0.8	0.3	-0.4	0.4	-1.1	-0.0	1.0
Worry too long after embarrassment	0.9	1.5	4.6	-0.1	-1.2	-0.5	-2.1	1.3	0.2	-1.4	0.5	1.8	-1.3
Age at last live birth	0.9	1.4	5.3	0.1	-0.6	-0.3	1.7	-1.1	1.1	2.3	1.0	0.1	-1.2
Leg pain on walking	0.9	1.2	3.0	-0.8	-1.1	-1.7	-1.1	1.0	0.7	0.1	1.6	0.6	-1.2
Average weekly red wine intake	0.9	1.3	5.1	2.3	-0.7	-0.3	0.4	-0.0	1.9	-1.6	-0.2	-0.6	1.0
Commuting to job workplace: Walk	0.9	1.0	5.5	1.2	0.5	0.2	1.3	-0.5	2.4	0.3	-0.0	0.7	-0.1
Number of self-reported non-cancer illnesses	0.9	1.6	4.4	-2.1	0.8	1.1	-1.3	0.2	-2.0	-0.6	-1.8	-0.4	-0.4
Ever had prostate specific antigen (PSA) test	0.9	1.1	3.3	-1.8	-0.2	-0.6	-1.6	1.4	-0.7	0.4	-0.2	0.8	-1.1
Vascular/heart problems diagnosed by doctor	0.9	2.4	5.0	1.5	1.2	2.2	1.3	-1.2	0.9	-1.1	-1.8	-1.7	1.9
Cholesterol lowering medication	0.9	1.3	3.2	-1.3	-1.2	-0.5	-1.5	1.8	-0.8	-0.4	0.2	-1.6	-1.0
Bipolar Disorder or Schizophrenia	0.8	2.0	9.5	-2.4	0.1	0.5	-0.5	0.1	-3.1	0.8	-1.1	-1.4	0.0
HbA1C	0.8	0.9	1.6	-1.0	-0.9	-1.0	-1.3	0.9	0.0	0.9	0.8	1.0	-1.3
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.2	-1.3	-1.0	-0.1	-1.4	1.1	-1.8	0.3	-0.1	-0.9	-0.7
Diabetes (mother)	0.8	1.0	2.2	0.9	1.4	1.5	-0.1	-0.6	-0.2	-0.6	-1.3	-0.4	1.4
Illnesses of siblings	0.8	1.1	4.4	0.3	0.9	1.1	1.1	-2.1	-1.0	-0.6	-1.2	-0.4	0.6
Alcohol intake versus 10 years previously	0.8	1.2	5.2	-2.3	0.9	0.4	-1.0	1.1	-1.7	0.1	-0.6	0.0	-0.5
Number of live births	0.8	1.2	3.7	-1.4	-0.7	-0.6	-1.9	1.2	-1.6	-0.8	0.4	-0.7	0.1
Prospective memory result	0.8	1.0	3.1	-1.2	-0.5	-1.4	0.8	1.7	-0.4	0.2	1.1	0.6	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.4	11.5	2.3	-0.8	-0.0	3.4	-0.9	2.1	-0.7	0.6	-0.4	0.5
Birth weight of first child	0.8	1.4	3.8	-1.0	-1.0	-0.7	0.3	-0.9	-1.5	2.0	1.1	1.2	-1.5
Smoking status: Previous	0.8	1.2	3.1	1.1	0.5	1.2	-0.5	-1.1	0.0	-1.8	-1.1	-0.9	1.5
Medication: Aspirin	0.8	1.0	4.5	-1.1	-0.5	-1.0	-2.1	1.0	-1.0	-0.9	0.4	-0.1	-0.7
Medication: Bendroflumethiazide	0.8	1.3	3.2	-0.9	-1.4	-1.5	-1.4	1.8	0.0	-0.6	1.0	0.8	-0.9
Risk taking	0.8	1.1	4.4	1.3	0.6	0.8	-0.2	-1.1	0.1	-2.1	-1.0	-0.1	1.3
Pain experienced in last month	0.8	1.4	3.4	0.7	1.6	1.5	0.6	-1.7	-0.1	0.6	-0.8	-1.0	1.8
Schizophrenia (2018)	0.7	1.4	6.8	-2.0	0.1	0.0	-0.9	0.2	-2.6	0.9	-0.6	-1.1	0.0
Mean Putamen Volume	0.7	0.8	2.4	1.6	0.6	-0.3	1.0	-0.7	0.4	-1.2	0.1	0.6	1.4
Waist Hip Ratio (WHR)	0.7	3.0	10.0	-2.5	-0.4	-0.9	-3.2	-0.2	-2.8	1.8	0.6	0.2	-1.1
Systolic Blood Pressure	0.7	3.4	9.6	3.1	-0.8	-0.6	2.9	-1.2	3.0	-0.6	1.7	1.0	0.6
Townsend deprivation index at recruitment	0.7	1.0	2.3	-1.4	1.0	0.9	-1.5	0.1	-0.7	0.5	-1.0	-1.4	0.7
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	2.1	0.6	0.5	1.2	-0.9	-0.4	0.2	-0.0	-1.3	-1.4	1.1
Serious illness, injury or assault to yourself	0.7	0.8	3.5	0.0	-0.3	-0.6	0.4	0.4	1.0	1.9	1.1	0.5	-1.3
Waist circumference	0.7	2.5	8.4	-2.9	1.1	0.6	-2.8	0.1	-2.1	0.2	-0.9	-1.3	-0.6
Alcohol usually taken with meals	0.7	1.1	3.5	1.9	-0.2	0.8	-0.8	-0.9	0.8	-1.0	-0.8	-1.5	0.7
Qualifications: None of the above	0.7	1.6	4.9	-2.2	0.2	-0.4	-1.2	2.0	-2.2	-0.1	-0.3	-0.5	-0.6
Financial difficulties in last 2 years	0.7	0.9	2.4	0.3	0.1	0.7	-1.5	0.7	-1.1	-0.9	-0.5	-1.6	1.1
Father’s age at death	0.7	1.0	3.4	0.2	-0.4	-0.6	1.0	-1.4	0.4	1.1	0.9	1.8	-0.6
Hair/balding pattern: Pattern 3	0.7	1.0	3.7	0.1	1.9	1.0	1.2	-0.4	-0.8	-0.4	-0.9	0.4	1.4
Ever highly irritable/argumentative for 2 days	0.7	0.8	5.3	-0.7	-0.3	0.2	-2.3	0.1	-0.7	0.5	-0.9	-0.4	-0.6
Exposure to tobacco smoke outside home	0.7	1.0	2.2	0.8	1.5	1.2	-0.0	-0.3	1.1	-1.0	-1.0	-0.5	1.4
Knee pain experienced in last month	0.7	1.0	2.5	-1.6	-1.2	-0.5	-1.2	0.8	-0.0	-1.0	-0.4	-0.6	-1.5
Medication for cholesterol	0.7	1.0	2.8	0.0	0.8	1.1	0.4	-0.8	-0.2	-1.4	-1.7	-0.6	1.5
Illnesses of father: None of the above (group 1)	0.7	0.8	2.2	0.3	1.5	1.2	0.9	-1.1	-0.3	-0.7	-1.1	-0.2	0.9
Pain type(s) experienced in last month: Hip pain	0.7	0.8	3.6	-1.3	0.3	0.0	-1.6	-0.2	-1.9	-0.2	-0.6	0.1	-0.1
Medication: Lisinopril	0.7	0.9	4.3	-0.8	0.8	0.0	-1.5	-0.5	-2.1	-0.3	-0.3	0.3	0.6
Number of operations (self-reported)	0.7	1.1	2.6	-1.5	1.1	0.6	-1.6	-0.5	-1.4	0.6	-1.2	-0.7	-0.1
Irritable Bowel Disease (IBD)	0.6	1.4	2.7	-0.6	-1.2	-1.5	0.2	1.5	0.7	0.3	1.6	1.6	-1.4
Crohns Disease (2012)	0.6	1.0	1.6	-1.3	-1.3	-0.9	-1.3	0.3	-1.1	1.2	0.5	0.5	-1.1
Schizophrenia (2014)	0.6	1.3	7.4	-2.0	0.4	0.2	-0.4	0.1	-2.7	0.1	-0.6	-0.7	0.5
Ulcerative Colitis	0.6	0.8	1.9	0.3	-0.6	-1.1	0.9	0.9	1.4	-0.3	1.3	1.0	-0.6
Neuroticism	0.6	1.5	7.5	-1.5	-0.0	-0.4	-2.7	1.4	-1.5	0.1	-0.2	0.2	-1.1
Average weekly spirits intake	0.6	0.8	2.0	0.2	1.1	0.8	-0.6	-0.2	0.0	-1.4	-1.0	-0.8	1.4
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	2.9	0.5	-0.4	0.0	1.4	0.2	1.7	-0.6	0.4	1.0	-0.7
Supplements: Zinc	0.6	0.6	1.4	-0.9	-0.4	-0.8	-1.0	1.2	-0.2	1.1	0.5	-0.2	-0.6
Trunk fat percentage	0.6	2.5	6.5	-1.6	2.5	1.7	-2.0	-0.6	-0.9	-0.5	-1.6	-2.1	0.7
Hayfever, allergic rhinitis or eczema	0.6	1.3	5.9	-1.6	1.2	0.9	-0.4	-1.0	-2.4	0.8	-0.9	-0.5	0.2
Had menopause	0.6	0.7	3.1	-0.8	-0.3	0.6	-1.8	-0.3	-1.3	0.6	-0.5	-0.6	0.5
Depression (self-reported)	0.6	0.8	2.3	-0.4	-1.3	-0.6	-1.2	1.5	-0.0	0.3	0.5	0.3	-1.1
Length of working week for main job	0.6	0.6	2.7	0.2	-0.1	0.2	-1.6	1.1	0.8	-1.0	-0.4	-0.6	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	2.4	-1.5	-0.6	-0.5	-0.6	0.9	-1.1	0.5	0.4	1.2	-1.5
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.7	-1.0	-0.4	-0.3	-1.1	-1.3	-0.7	1.6	-0.3	-0.3	-0.8
Headache pain in last month	0.6	1.0	4.0	-0.6	-0.8	-1.3	-0.9	0.7	-0.0	0.3	0.8	2.0	-1.2
Gout (self-reported)	0.6	0.8	3.9	-2.0	-0.7	-0.0	-0.1	0.4	-1.3	0.1	-0.5	0.5	-1.0
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.9	0.8	0.4	0.7	0.9	0.2	0.9	-1.4	-0.4	1.7	0.1
Body fat percentage	0.6	2.4	6.3	-1.3	2.5	1.8	-2.2	-0.4	-0.7	-0.7	-1.6	-2.0	0.7
Leg fat percentage (right)	0.6	2.0	4.6	-1.3	1.9	1.7	-2.1	0.0	-0.3	-0.8	-1.5	-2.0	0.6
Age at first live birth	0.6	1.1	4.5	0.4	0.8	0.8	1.2	-1.8	0.8	2.1	0.1	0.2	-0.5
Shortness of breath walking on level ground	0.6	0.8	3.1	1.8	0.6	0.4	0.8	-1.4	0.6	0.7	0.3	0.5	0.4
Medication: Blood pressure	0.6	1.1	2.8	-0.7	-0.2	-1.7	-1.5	0.5	-0.5	0.7	1.3	1.4	-0.8
Medication: Allopurinol	0.6	0.8	3.2	-1.8	0.0	0.2	-1.0	0.3	-1.4	0.6	-0.5	0.0	-1.0
Medication: Omeprazole	0.6	0.7	3.4	1.8	-0.0	0.0	-0.3	-1.0	1.2	-0.4	0.1	1.1	0.1
Medication: Seretide 50 evohaler	0.6	0.7	2.8	-0.6	0.3	-0.9	0.9	1.0	0.2	0.1	0.7	1.7	-1.0
Number of full sisters	0.6	0.7	4.4	1.1	-0.1	0.2	0.0	0.8	2.1	0.6	0.5	-0.0	0.1
Friendships satisfaction	0.6	0.7	1.8	0.4	0.2	-0.3	1.3	0.4	1.2	1.3	0.8	0.7	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.4	1.2	-1.2	-0.4	0.9	1.3	0.7	-1.0	0.3	-1.5	-0.5
Back pain experienced in last month	0.6	0.9	1.8	-1.0	-0.9	-0.9	-1.4	1.1	-0.8	0.9	0.4	-0.7	-1.2
Smoking status: Current	0.6	1.0	6.2	-1.0	0.2	-0.4	-1.1	2.5	-0.7	0.2	0.3	-0.1	-0.5
Commuting to job workplace: Public transport	0.6	0.7	2.0	-0.5	-1.2	-0.6	0.4	0.8	0.7	1.4	0.6	-1.0	-0.6
Medication: Paracetamol	0.6	0.9	3.2	0.8	1.4	0.9	-1.8	-0.8	0.6	-0.5	-1.0	-0.4	0.7
Commuting to job workplace: Cycle	0.6	0.8	2.4	1.0	0.9	0.2	-0.5	-0.7	1.5	-0.5	0.2	1.6	0.6
Myopia	0.6	0.8	2.9	-1.7	0.5	-0.1	-1.1	0.8	-1.4	0.6	-0.5	-0.7	0.0
Intelligence (Savage-Jansen 2018)	0.5	1.6	4.3	2.1	1.3	0.7	-0.1	-0.9	1.9	-1.4	-0.2	-0.4	1.7
Alzheimer’s Disease (in mother)	0.5	0.5	2.2	-0.9	-0.9	-0.2	-1.5	0.3	-0.8	-0.2	-0.3	-0.6	-0.3
HDL Cholesterol	0.5	0.9	2.9	0.2	0.7	1.4	-0.0	-1.7	-0.4	-0.1	-1.3	-1.0	0.8
Blood Eosinophil Count	0.5	4.2	16.6	-3.3	-0.3	-1.2	-2.9	0.9	-4.1	1.2	0.7	0.1	-1.4
Lung FEV1/FVC ratio	0.5	2.4	15.8	-0.4	-2.4	0.0	0.0	-0.1	1.0	0.8	0.2	-4.0	0.6
Number of treatments/medications taken	0.5	0.8	3.0	-1.0	0.2	-0.8	-1.7	1.1	-0.5	0.2	0.2	0.7	-1.2
Vitamin and mineral supplements	0.5	0.7	1.8	-0.6	0.1	-0.6	-1.3	0.7	-1.1	0.2	0.9	1.3	-0.5
Current tobacco smoking	0.5	0.9	4.8	-0.8	0.4	-0.1	-1.5	2.2	-0.8	-0.0	0.0	-0.4	-0.2
Average weekly fortified wine intake	0.5	0.6	4.0	-0.4	0.1	-0.3	-2.0	-0.0	0.5	-1.0	0.1	0.1	0.5
High blood pressure	0.5	1.4	2.9	-1.1	-0.9	-1.7	-0.6	0.5	-0.4	1.3	1.6	1.1	-1.7
Trunk fat mass	0.5	2.0	5.1	-1.5	2.3	1.6	-1.5	-0.7	-0.6	-0.9	-1.5	-1.8	0.5
Hair/balding pattern: Pattern 2	0.5	0.7	2.0	0.8	-1.4	-1.0	-0.1	0.4	0.5	0.4	1.1	-0.7	-0.9
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	8.5	2.0	-1.1	-0.2	2.9	-0.5	1.9	-0.7	0.5	-0.1	0.2
Happiness	0.5	0.5	2.9	1.2	0.2	0.7	0.2	-0.4	1.7	-0.1	-0.4	-0.2	-0.2
Noisy workplace	0.5	0.6	2.3	0.4	1.5	0.6	1.0	-0.9	-0.0	-0.5	-0.5	-0.3	1.0
Lung cancer (father)	0.5	0.6	1.6	-0.3	0.8	0.7	-1.1	-0.3	-1.2	0.5	-0.5	-0.8	0.6
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	2.5	0.2	-0.3	0.9	1.2	-0.2	0.1	-1.6	-0.9	-1.2	0.6
Forced vital capacity (FVC), Best measure	0.5	1.8	9.7	2.0	-0.6	-0.1	3.1	-0.8	1.5	-1.0	0.5	0.1	0.2
Qualifications: College or University degree	0.5	1.7	6.2	1.2	-1.1	-0.6	0.6	-0.7	2.5	0.5	1.5	1.6	-1.4
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.3	-0.5	0.3	0.6	-0.4	-0.4	-1.1	-1.5	-1.1	0.1	0.8
Hypertension (Self-reported)	0.5	1.3	3.0	-1.0	-1.1	-1.7	-0.1	0.5	-0.2	0.9	1.6	1.0	-1.6
Mood swings	0.5	0.8	4.5	-0.7	-0.4	-0.6	-2.1	0.9	-0.8	-1.0	0.3	0.4	-0.1
Hearing aid user	0.5	0.5	3.5	0.9	-0.3	0.1	-0.2	0.2	0.1	-1.9	0.1	-0.4	0.7
Medication: Blood pressure	0.5	0.9	1.8	-1.4	-1.0	-1.0	-0.9	1.0	-0.6	0.3	1.1	0.1	-1.2
Leg fat percentage (left)	0.5	1.9	5.1	-1.5	1.9	1.5	-2.3	0.1	-0.5	-0.5	-1.4	-1.8	0.3
Alcohol drinker status: Previous	0.5	0.6	1.6	-0.1	-0.0	0.4	-1.3	0.0	-0.9	-0.9	-1.0	-0.7	1.1
Bipolar Disorder (2018)	0.4	0.7	2.8	-1.3	0.1	0.8	0.3	-0.1	-1.7	0.3	-1.1	-0.8	-0.0
Crohns Disease (2017)	0.4	0.9	1.9	-1.2	-1.4	-0.9	-0.4	0.6	-0.8	0.8	0.7	1.1	-1.2
Body Mass Index (BMI) (2010)	0.4	0.6	1.6	-0.7	-0.8	-0.7	-0.4	0.4	-0.5	0.8	1.3	0.3	-1.0
Fasting Glucose	0.4	0.5	1.6	0.9	0.2	0.9	1.2	-0.6	-0.2	-0.6	-0.3	-1.1	0.4
Lupus	0.4	0.7	2.4	-1.2	0.9	-0.0	-0.7	0.0	-1.5	-0.2	-0.7	-0.7	0.7
Lung FVC	0.4	2.2	7.5	2.4	-1.3	-0.7	2.0	0.8	2.7	-0.9	1.1	-0.1	0.0
Medication: Co-codamol	0.4	0.4	2.1	-0.9	-0.6	-0.1	-0.7	0.2	-0.2	0.6	0.0	-0.2	-1.5
Fed-up feelings	0.4	0.7	5.0	-0.7	0.1	-0.6	-2.2	0.8	-0.7	-0.4	0.4	-0.3	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	3.3	-0.9	1.8	1.2	-0.1	-0.4	-0.2	-0.7	-1.8	-0.3	0.7
Stomach or abdominal pain in last month	0.4	0.4	0.8	0.4	0.9	0.9	-0.9	0.1	0.4	0.0	-0.9	-0.6	0.7
Nervous feelings	0.4	0.7	2.2	-0.1	-1.5	-0.9	0.0	1.1	0.3	0.5	1.1	0.5	-0.9
Forced vital capacity (FVC)	0.4	1.7	6.8	1.4	-1.3	-0.8	2.6	0.4	1.4	-0.8	1.0	1.3	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	2.7	-0.8	1.4	1.0	-0.7	-0.3	-0.9	-0.7	-1.6	-0.2	1.1
Fluid intelligence score	0.4	0.8	2.0	1.3	0.6	0.7	-1.4	-1.1	0.5	-1.2	-0.5	-0.4	0.6
Asthma	0.4	0.9	2.3	-1.5	0.4	-0.8	-0.3	1.3	-1.3	-0.1	0.0	0.9	-1.2
Tense / ‘highly strung’	0.4	0.7	3.2	-1.1	-0.5	-0.4	-1.8	0.4	-0.6	0.8	0.5	0.1	-0.7
Medication: Paracetamol	0.4	0.6	1.8	1.3	0.7	0.6	-1.3	-0.6	0.9	-0.2	-0.5	-0.3	0.5
Medication for pain relief, constipation, heartburn	0.4	0.7	4.1	-0.4	-1.1	-0.5	2.0	0.1	0.8	0.3	0.6	0.2	0.1
Whole body fat mass	0.4	1.7	4.1	-1.4	2.0	1.3	-1.7	-0.4	-0.5	-1.1	-1.3	-1.6	0.4
Leg fat mass (right)	0.4	1.6	4.2	-1.5	2.1	1.4	-1.8	-0.2	-0.4	-0.9	-1.3	-1.4	0.3
Suffer from ‘nerves’	0.4	0.6	1.6	0.3	-1.1	-1.3	-0.7	0.9	0.4	0.2	1.0	0.4	-0.6
Medication: Aspirin	0.4	0.6	3.3	-0.8	-0.1	-0.5	-1.8	0.5	-0.9	-0.7	-0.0	-0.5	-0.2
Arm fat percentage (left)	0.4	1.5	4.2	-1.0	2.0	1.2	-2.0	0.1	-0.2	-0.8	-1.1	-1.5	0.3
Qualifications: nursing, teaching	0.4	0.7	1.9	1.0	-0.3	-0.3	0.1	0.2	1.2	-1.3	0.1	1.4	-0.4
Mineral and other dietary supplements	0.4	0.5	1.3	-0.3	1.2	-0.1	0.1	-1.1	-1.1	0.7	0.1	0.8	0.7
Asthma (self-reported)	0.4	0.8	2.1	-1.4	0.5	-0.6	-0.3	1.2	-1.2	-0.2	-0.2	0.9	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	1.7	-0.8	-1.2	-1.3	-0.1	0.5	0.4	0.9	0.9	0.9	-1.1
Average weekly champagne plus white wine intake	0.4	0.5	2.3	0.4	-0.8	-0.0	0.7	-1.5	0.5	0.3	0.2	-0.8	-0.5
Supplements: Fish oil (including cod liver oil)	0.4	0.5	2.0	-0.3	-0.7	0.7	-0.3	0.6	0.1	0.5	-0.6	-1.4	-0.7
Alcohol drinker status: Never	0.4	0.5	1.7	0.0	1.3	0.7	-0.2	-0.8	-0.6	0.3	-0.7	-0.9	0.9
Supplements: Calcium	0.4	0.5	1.3	0.5	-1.0	-0.6	0.5	0.4	1.2	0.4	0.7	0.5	-0.8
Leg fat mass (left)	0.4	1.5	4.0	-1.6	2.0	1.3	-1.8	-0.1	-0.6	-0.8	-1.2	-1.2	0.1
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.9	-1.0	0.3	0.7	0.5	-0.6	-0.2	-0.2	-0.5	-0.5	0.6
BMI	0.3	1.9	8.8	-2.4	0.4	-0.5	-3.0	1.1	-1.2	0.1	0.1	-0.2	-1.1
Smoking Status	0.3	0.6	1.6	-0.5	1.0	0.5	-1.2	1.3	-0.3	-1.0	-0.6	-0.5	0.5
Cardiovascular Disease	0.3	1.0	2.0	1.2	-1.2	-0.7	0.8	-0.3	1.1	0.8	1.4	1.2	-1.1
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.6	1.3	1.0	0.8	0.1	-0.7	1.1	-0.8	-0.7	0.2	0.5
Tanning	0.3	3.6	8.4	-1.9	-2.4	-2.0	-1.2	2.2	-0.8	0.7	1.6	2.1	-2.9
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.0	1.0	0.6	0.8	-0.6	-0.0	0.7	0.7	-0.3	-0.9	0.3
Ever had hysterectomy (womb removed)	0.3	0.4	1.5	-0.1	0.6	-0.0	-1.1	1.2	-0.3	-0.7	-0.2	-0.0	0.2
Impedance of leg (right)	0.3	1.4	3.6	0.4	1.2	1.6	-0.8	-1.2	-0.6	0.1	-1.5	-1.2	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	2.0	-0.3	-0.1	0.4	-1.0	0.1	-1.4	0.6	-0.3	-0.9	-0.4
Multivitamins +/- minerals	0.3	0.4	2.5	0.3	-0.1	0.6	0.3	-0.7	0.1	0.4	-0.8	-1.6	0.2
Chronic bronchitis/emphysema (father)	0.3	0.4	1.4	-0.3	1.0	-0.4	-0.9	1.2	-0.2	-0.3	-0.1	0.1	0.0
Arm fat percentage (right)	0.3	1.0	3.4	-1.1	1.7	0.9	-1.9	0.3	-0.1	-0.5	-0.7	-1.1	-0.1
Medication: Cholesterol lowering	0.3	0.5	1.2	-0.6	0.0	-0.9	-0.5	0.7	0.2	1.1	0.8	1.0	-0.7
Medication: Amlodipine	0.3	0.4	2.0	-0.5	-0.2	-0.1	-1.4	0.8	-1.2	-0.2	-0.1	-0.1	-0.2
Health satisfaction	0.3	0.4	1.6	-0.2	-1.3	-0.4	-0.2	0.9	-0.1	0.3	0.5	-0.8	-0.8
Neck or shoulder pain in last month	0.3	0.4	2.9	-0.7	-0.0	-0.2	-1.7	0.3	-0.2	0.1	-0.3	0.3	-0.4
Comparative height size at age 10	0.3	1.7	4.6	-1.6	-1.8	-1.3	0.6	-0.2	-0.0	0.7	1.3	1.6	-2.1
Had major operations	0.3	0.4	1.8	-1.3	-0.4	-0.6	0.1	0.5	-0.1	0.2	0.3	0.5	-0.7
Family relationship satisfaction	0.3	0.4	1.0	-0.3	-0.0	-0.2	1.0	0.3	0.3	0.9	0.8	0.4	-0.8
Supplements: Vitamin C	0.3	0.3	1.7	0.9	0.3	0.3	0.6	0.1	1.3	-0.1	-0.2	-0.1	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.6	0.6	0.4	-0.6	0.8	-0.9	-0.4	0.6	0.8	1.3	-0.9
High cholesterol (Self-reported)	0.3	0.5	2.1	0.1	-0.3	-0.2	-0.5	1.4	1.0	-1.0	0.1	-0.8	-0.5
Medication: Atorvastatin	0.3	0.4	1.6	-0.3	-0.4	-0.7	-0.6	0.0	-0.3	0.1	0.5	1.3	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.2	0.8	-0.0	-0.2	-0.3	-1.1	0.3	0.1	0.2	1.0	-0.3
Worry (Nagel 2018)	0.2	0.5	2.0	0.2	-0.3	-0.6	-1.4	0.2	0.1	1.2	0.6	0.2	-0.5
Verbal and Numeric Reasoning (VNR)	0.2	0.6	3.0	0.9	0.4	0.5	-1.7	-0.7	0.2	-0.7	-0.1	0.7	0.5
Ovarian Cancer	0.2	0.3	1.0	0.5	-0.5	0.4	0.5	-0.2	-0.4	-1.0	-0.5	-0.3	0.9
Rheumatoid Arthritis	0.2	0.3	0.6	0.1	-0.7	-0.3	0.4	0.8	0.4	-0.7	0.8	0.1	0.4
Allergy or Eczema	0.2	0.5	1.7	-0.8	0.7	0.6	0.4	-0.8	-1.3	0.8	-0.4	0.4	0.1
Systolic blood pressure, automated reading	0.2	0.7	2.8	1.1	-0.4	-0.5	0.9	-0.5	1.7	0.0	1.0	-0.1	0.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.7	0.5	-0.4	-0.1	0.2	0.4	0.4	-0.8	-0.0	-0.5	-0.3
Pack years adult smoking proportion	0.2	0.3	1.0	-0.5	1.0	0.2	-0.0	0.8	-0.6	0.4	0.0	-0.5	0.4
Sitting height	0.2	1.5	5.9	0.5	0.3	1.5	2.1	-2.4	0.6	-0.4	-1.0	-0.5	0.5
Body mass index (BMI)	0.2	0.8	2.4	-1.3	1.2	0.4	-1.5	0.7	-0.3	-1.0	-0.4	-0.9	-0.4
Impedance of leg (left)	0.2	1.0	2.1	0.2	1.2	1.4	-0.9	-1.0	-0.7	0.6	-1.2	-0.7	1.4
Weight	0.2	0.8	1.9	-1.4	1.3	1.0	-0.6	-0.6	-0.6	-0.9	-0.9	-0.9	-0.3
Worrier / anxious feelings	0.2	0.5	1.8	-0.8	0.2	-0.3	-1.4	0.4	-0.7	0.5	0.1	0.8	-0.7
Pulse wave Arterial Stiffness index	0.2	0.3	0.7	0.1	0.8	0.4	0.9	-0.5	0.4	-0.3	-0.1	0.6	0.6
Impedance of arm (left)	0.2	1.0	2.9	0.7	1.2	1.2	-0.3	-1.1	0.1	0.2	-1.1	-1.1	1.7
Arm fat mass (right)	0.2	1.0	2.6	-1.5	1.6	0.7	-1.6	0.1	-0.4	-0.8	-0.7	-0.9	-0.2
Standing height	0.2	1.7	9.4	-0.4	0.6	1.3	1.9	-3.1	-0.6	0.0	-1.2	-0.2	0.3
Pulse wave reflection index	0.2	0.2	0.9	0.4	0.7	0.3	0.4	0.2	0.3	0.1	-0.1	1.0	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.6	-0.4	0.3	-0.3	0.8	-0.3	0.1	0.8	0.5	0.7	-0.7
Pulse wave peak to peak time	0.2	0.2	0.6	-0.2	-0.8	-0.3	-0.7	0.2	-0.4	0.0	0.0	-0.6	-0.5
Medication: Ibuprofen	0.2	0.2	1.2	0.3	1.1	0.4	-0.5	-0.0	0.4	0.1	-0.5	0.6	-0.0
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.8	0.4	0.3	0.6	0.6	-0.0	-0.5	-0.9	-0.5	-0.1	0.7
Illnesses of father: Heart disease	0.2	0.3	0.9	-0.1	-0.9	-0.5	0.0	0.2	0.5	0.7	0.7	0.6	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	1.1	-0.6	0.1	0.0	-0.9	1.0	-0.7	-0.1	0.3	-0.1	-0.4
Arm fat mass (left)	0.2	0.9	2.5	-1.4	1.6	0.7	-1.6	-0.0	-0.4	-0.7	-0.6	-0.9	-0.2
Wears glasses or contact lenses	0.2	0.2	0.7	0.0	-0.5	-0.8	-0.4	0.6	0.1	0.6	0.6	-0.5	0.0
Ever taken oral contraceptive pill	0.2	0.3	0.6	0.8	-0.1	-0.5	-0.6	-0.5	-0.1	-0.2	0.1	0.7	-0.6
Diastolic blood pressure, automated reading	0.2	0.7	1.5	0.1	-1.0	-1.1	0.8	0.1	1.0	-0.1	1.2	0.7	-0.6
Pack years of smoking	0.2	0.3	1.4	-0.6	0.9	0.0	-0.2	1.2	-0.5	0.3	0.1	-0.2	0.3
Impedance of whole body	0.2	1.1	2.5	0.3	0.9	1.3	-0.8	-1.1	-0.6	0.5	-1.3	-1.1	1.6
LDL Cholesterol	0.1	0.1	0.5	0.2	0.0	0.2	-0.4	-0.2	-0.3	0.7	-0.1	-0.4	-0.0
Primary Biliary Cirrhosis	0.1	0.2	0.6	-0.2	-0.0	-0.1	0.5	0.3	0.0	0.7	0.8	0.6	-0.4
Heel T-Score	0.1	1.0	4.0	0.2	2.0	1.1	0.6	-1.0	-0.4	0.1	-1.5	-0.6	1.0
Height	0.1	1.4	5.2	-1.6	-0.1	0.6	0.7	-2.3	-2.0	0.1	-0.4	0.6	-0.6
Hair Pigment	0.1	1.5	3.8	-1.9	1.0	-0.1	-1.5	-0.5	-1.9	2.0	-0.3	-0.1	-0.2
Leg fat-free mass (left)	0.1	0.3	0.9	-1.0	0.5	0.3	0.7	-0.7	-0.3	-0.7	-0.2	-0.3	-0.7
Leg predicted mass (left)	0.1	0.3	1.0	-1.0	0.4	0.2	0.6	-0.7	-0.3	-0.7	-0.2	-0.3	-0.7
Past tobacco smoking	0.1	0.3	1.3	-0.6	0.0	-0.5	0.6	-0.1	0.1	1.1	0.2	0.2	-0.5
Diabetes (self-reported)	0.1	0.1	0.5	-0.2	-0.2	-0.5	-0.7	0.2	0.1	-0.1	0.4	0.0	-0.5
Impedance of arm (right)	0.1	0.5	1.5	1.1	0.7	0.7	0.2	-0.6	0.6	0.1	-0.4	-0.3	1.2
Trunk fat-free mass	0.1	0.4	1.3	-0.7	-0.0	0.2	1.1	-1.1	-0.3	-0.6	-0.1	0.4	-0.8
Hip circumference	0.1	0.5	1.6	-1.3	1.1	0.8	-0.5	-0.0	-0.2	-0.5	-0.4	-0.3	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.4	0.6	0.6	-0.0	-0.4	0.3	0.1	0.0	-0.1	0.5	-0.4
Trunk predicted mass	0.1	0.4	1.3	-0.6	-0.1	0.2	1.1	-1.1	-0.3	-0.5	-0.1	0.4	-0.9
Birth weight	0.1	0.3	1.0	-1.0	0.7	0.2	-0.6	-0.5	-0.8	0.2	-0.3	0.2	0.1
Arm fat-free mass (right)	0.1	0.5	1.8	-1.0	0.4	0.6	0.7	-1.3	-0.6	-0.3	-0.5	-0.3	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.3	-0.2	0.2	0.2	-0.2	0.5	-0.4	-0.3	-0.5	-0.2	0.2
Arm predicted mass (right)	0.1	0.4	1.1	-1.0	0.2	0.5	0.4	-1.0	-0.4	-0.4	-0.4	-0.4	-0.7
Whole body fat-free mass	0.1	0.4	0.9	-1.0	0.2	0.2	0.9	-0.9	-0.3	-0.6	-0.1	0.1	-0.9
Leg fat-free mass (right)	0.1	0.3	1.1	-1.0	0.4	-0.1	0.8	-0.5	-0.1	-0.4	0.1	0.1	-1.0
Diabetes diagnosed by doctor	0.1	0.1	1.0	-0.2	0.1	-0.2	-1.0	-0.0	-0.0	-0.0	0.1	-0.4	-0.2
Whole body water mass	0.1	0.4	1.0	-0.9	0.0	0.0	0.9	-0.9	-0.2	-0.5	0.1	0.2	-1.0
Leg predicted mass (right)	0.1	0.4	1.2	-1.0	0.3	-0.2	0.9	-0.6	-0.1	-0.3	0.3	0.2	-1.1
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.9	-0.2	0.1	-0.4	-0.1	1.0	0.1	-0.6	0.2	0.2	-0.1
Ever smoked	0.1	0.2	0.9	0.3	-0.5	-0.1	-1.0	0.4	0.2	-0.4	0.5	0.0	-0.4
Basal metabolic rate	0.1	0.4	1.0	-1.0	0.4	0.3	0.6	-0.9	-0.3	-0.6	-0.2	-0.1	-0.9
Arm fat-free mass (left)	0.1	0.4	1.4	-1.1	-0.2	0.1	0.6	-1.0	-0.5	-0.1	0.0	0.0	-1.2
Arm predicted mass (left)	0.1	0.4	1.2	-1.1	-0.2	0.2	0.7	-0.9	-0.4	-0.2	0.0	-0.1	-1.1

Hub : Genes

RRM2B

Models

Trait associations