TWAS
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Traits
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Blood Platelet Count
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chr8:130,365,025-132,153,671
Best TWAS P=3.7e-16 · Best GWAS P=1.69e-23 conditioned to 7.55e-09
130.5M
131M
131.5M
132M
0
5
10
15
20
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Colon Adenocarcinoma
ASAP1
0.1
0.06
lasso
2
0.07
9.2e-05
8.6
8.2
3.7e-16
-0.82
0.06
0.79
TRUE
1
CommonMind
Brain Pre-frontal Cortex
ASAP1
0.1
0.08
lasso
5
0.09
5.0e-11
8.6
7.7
1.5e-14
-0.81
0.06
0.94
FALSE