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Traits
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Blood Platelet Count
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chr9:126,321,003-127,872,298
Best TWAS P=1.31e-10 · Best GWAS P=4.84e-27 conditioned to 3.78e-15
126.4M
126.6M
126.8M
127M
127.2M
127.4M
127.6M
127.8M
0
5
10
15
20
25
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
GTEx
Nerve Tibial
NEK6
0.11
0.02
enet
40
0.03
3.9e-03
3.1
-6.4
1.3e-10
-0.59
0.01
0.93
TRUE
5
GTEx
Thyroid
PSMB7
0.06
0.04
lasso
2
0.06
4.1e-05
5.9
-6.3
3.6e-10
-0.40
0.48
0.30
TRUE
1
GTEx
Adipose Subcutaneous
PSMB7
0.08
0.04
lasso
6
0.04
3.4e-04
6.1
-5.8
8.7e-09
-0.37
0.85
0.02
FALSE
3
GTEx
Colon Sigmoid
PSMB7
0.15
0.10
lasso
3
0.09
3.3e-04
5.6
-5.6
2.3e-08
-0.33
0.48
0.05
FALSE
2
GTEx
Artery Tibial
PSMB7
0.07
0.04
enet
7
0.03
4.1e-03
6.1
-5.6
2.6e-08
-0.33
0.56
0.03
FALSE