[Hub]/) : Traits : Blood Platelet Count : ← →

chr2:23,453,834-25,040,082

Best TWAS P=3.47e-14 · Best GWAS P=2.55e-14 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex UBXN2A 0.22 0.18 enet 28 0.24 3.0e-28 -5.8 7.3 3.0e-13 -0.92 0.10 0.90 FALSE
2 GTEx Artery Aorta UBXN2A 0.20 0.09 lasso 6 0.08 4.1e-05 7.0 5.2 2.0e-07 -0.02 0.75 0.24 FALSE
3 GTEx Esophagus Gastroesophageal Junction PFN4 0.13 0.01 lasso 12 0.01 9.7e-02 -6.3 -5.7 1.6e-08 0.71 0.07 0.38 FALSE
4 GTEx Esophagus Mucosa UBXN2A 0.12 0.06 lasso 6 0.05 1.9e-04 6.4 5.4 7.8e-08 -0.18 0.62 0.15 FALSE
5 GTEx Esophagus Muscularis UBXN2A 0.08 0.07 lasso 6 0.06 2.4e-04 6.4 6.2 5.5e-10 -0.22 0.57 0.13 FALSE
6 GTEx Heart Atrial Appendage UBXN2A 0.08 0.02 lasso 3 0.02 5.2e-02 -7.6 -6.0 2.5e-09 0.97 0.02 0.95 FALSE
7 GTEx Heart Atrial Appendage PFN4 0.22 0.06 lasso 7 0.10 2.8e-05 3.2 -6.0 1.5e-09 0.64 0.10 0.86 FALSE
8 GTEx Muscle Skeletal UBXN2A 0.10 0.04 lasso 7 0.03 5.5e-04 6.4 5.6 1.7e-08 -0.02 0.84 0.15 TRUE
9 GTEx Stomach UBXN2A 0.13 0.14 enet 5 0.14 3.6e-07 7.0 5.4 5.5e-08 0.02 0.54 0.36 FALSE
10 METSIM Adipose PFN4 0.04 0.01 blup 306 0.03 1.9e-05 -3.4 -5.5 3.4e-08 0.71 0.19 0.69 FALSE
11 ROSMAP Brain Pre-frontal Cortex UBXN2A 0.03 0.01 lasso 4 0.02 2.2e-03 -7.6 6.3 2.7e-10 -0.83 0.02 0.95 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma UBXN2A 0.04 0.04 lasso 1 0.03 1.4e-04 -7.6 7.6 3.5e-14 -0.99 0.00 0.99 TRUE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma UBXN2A 0.03 0.02 blup 46 0.03 5.7e-04 6.4 5.5 2.8e-08 -0.04 0.31 0.28 FALSE