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chr2:23,453,834-25,040,082

Best TWAS P=3.47e-14 · Best GWAS P=2.55e-14 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	UBXN2A	0.04	0.04	lasso	1	0.03	1.4e-04	-7.6	7.6	3.5e-14	-0.99	0.00	0.99	TRUE
8	GTEx	Muscle Skeletal	UBXN2A	0.10	0.04	lasso	7	0.03	5.5e-04	6.4	5.6	1.7e-08	-0.02	0.84	0.15	TRUE
1	CommonMind	Brain Pre-frontal Cortex	UBXN2A	0.22	0.18	enet	28	0.24	3.0e-28	-5.8	7.3	3.0e-13	-0.92	0.10	0.90	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	UBXN2A	0.03	0.01	lasso	4	0.02	2.2e-03	-7.6	6.3	2.7e-10	-0.83	0.02	0.95	FALSE
5	GTEx	Esophagus Muscularis	UBXN2A	0.08	0.07	lasso	6	0.06	2.4e-04	6.4	6.2	5.5e-10	-0.22	0.57	0.13	FALSE
7	GTEx	Heart Atrial Appendage	PFN4	0.22	0.06	lasso	7	0.10	2.8e-05	3.2	-6.0	1.5e-09	0.64	0.10	0.86	FALSE
6	GTEx	Heart Atrial Appendage	UBXN2A	0.08	0.02	lasso	3	0.02	5.2e-02	-7.6	-6.0	2.5e-09	0.97	0.02	0.95	FALSE
3	GTEx	Esophagus Gastroesophageal Junction	PFN4	0.13	0.01	lasso	12	0.01	9.7e-02	-6.3	-5.7	1.6e-08	0.71	0.07	0.38	FALSE
13	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UBXN2A	0.03	0.02	blup	46	0.03	5.7e-04	6.4	5.5	2.8e-08	-0.04	0.31	0.28	FALSE
10	METSIM	Adipose	PFN4	0.04	0.01	blup	306	0.03	1.9e-05	-3.4	-5.5	3.4e-08	0.71	0.19	0.69	FALSE
9	GTEx	Stomach	UBXN2A	0.13	0.14	enet	5	0.14	3.6e-07	7.0	5.4	5.5e-08	0.02	0.54	0.36	FALSE
4	GTEx	Esophagus Mucosa	UBXN2A	0.12	0.06	lasso	6	0.05	1.9e-04	6.4	5.4	7.8e-08	-0.18	0.62	0.15	FALSE
2	GTEx	Artery Aorta	UBXN2A	0.20	0.09	lasso	6	0.08	4.1e-05	7.0	5.2	2.0e-07	-0.02	0.75	0.24	FALSE