Best TWAS P=2.3e-20 · Best GWAS P=9.07e-25 conditioned to 1.81e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | TRIB2 | 0.17 | 0.03 | lasso | 7 | 0.04 | 2.9e-03 | -7.7 | -9.2 | 2.3e-20 | 0.80 | 0.04 | 0.92 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | TRIB2 | 0.13 | 0.06 | enet | 19 | 0.12 | 1.6e-14 | -7.8 | -7.4 | 1.4e-13 | 0.73 | 0.09 | 0.91 | FALSE |
| 5 | YFS | Blood | TRIB2 | 0.04 | 0.01 | enet | 16 | 0.03 | 2.6e-09 | -3.3 | -6.6 | 3.3e-11 | 0.64 | 0.17 | 0.83 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | TRIB2 | 0.04 | 0.01 | blup | 56 | 0.01 | 2.3e-02 | -6.5 | -6.6 | 3.8e-11 | 0.65 | 0.03 | 0.25 | FALSE |
| 2 | METSIM | Adipose | TRIB2 | 0.06 | 0.03 | bslmm | 475 | 0.02 | 1.5e-04 | -6.4 | -6.4 | 1.7e-10 | 0.49 | 0.08 | 0.61 | FALSE |
| 3 | NTR | Blood | TRIB2 | 0.03 | 0.00 | blup | 477 | 0.01 | 7.2e-04 | 5.8 | -5.1 | 2.9e-07 | 0.46 | 0.08 | 0.27 | FALSE |