Best TWAS P=4.86e-14 · Best GWAS P=1.63e-13 conditioned to 0.0574
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | RP11-554A11.9 | 0.49 | 0.17 | lasso | 9 | 0.20 | 8.5e-06 | 7.4 | 5.6 | 2.2e-08 | 0.83 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | RP11-554A11.9 | 0.23 | 0.08 | lasso | 4 | 0.08 | 6.7e-03 | 3.7 | 5.1 | 2.7e-07 | 0.71 | 0.05 | 0.36 | FALSE |
| 3 | GTEx | Colon Transverse | RP11-554A11.9 | 0.26 | 0.11 | lasso | 9 | 0.10 | 2.5e-05 | 5.1 | 6.0 | 2.5e-09 | 0.75 | 0.02 | 0.93 | FALSE |
| 4 | GTEx | Heart Atrial Appendage | RP11-554A11.9 | 0.24 | 0.05 | lasso | 8 | 0.09 | 9.5e-05 | 2.4 | 5.5 | 2.9e-08 | 0.56 | 0.03 | 0.80 | FALSE |
| 5 | GTEx | Lung | RP11-554A11.9 | 0.28 | 0.10 | enet | 34 | 0.20 | 1.6e-15 | 3.8 | 5.2 | 1.8e-07 | 0.58 | 0.10 | 0.90 | FALSE |
| 6 | GTEx | Prostate | RP11-554A11.9 | 0.44 | 0.11 | enet | 13 | 0.18 | 2.8e-05 | 7.4 | 7.5 | 4.9e-14 | 0.84 | 0.01 | 0.94 | TRUE |
| 7 | GTEx | Vagina | RP11-554A11.9 | 0.49 | 0.11 | lasso | 6 | 0.12 | 9.5e-04 | 7.4 | 6.5 | 6.3e-11 | 0.80 | 0.02 | 0.78 | FALSE |