[Hub]/) : Traits : Blood Platelet Count : ← →

chr11:70,807,773-73,149,098

Best TWAS P=2.9e-09 · Best GWAS P=1.22e-15 conditioned to 6.98e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere FAM86C1 0.35 0.20 lasso 5 0.16 5.7e-05 -4.5 -5.2 2.7e-07 0.00 0.03 0.88 FALSE
2 GTEx Esophagus Mucosa ARAP1 0.27 0.25 lasso 5 0.26 2.6e-17 4.6 5.9 2.9e-09 0.74 0.78 0.22 TRUE
3 GTEx Esophagus Mucosa ARAP1-AS2 0.12 0.08 lasso 6 0.08 3.1e-06 4.6 5.7 1.3e-08 0.72 0.02 0.95 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic ARAP1 0.24 0.20 lasso 4 0.16 3.6e-09 4.6 5.5 4.9e-08 0.69 0.39 0.61 FALSE
5 GTEx Skin Sun Exposed Lower leg FAM86C1 0.40 0.31 lasso 6 0.35 7.2e-30 -4.5 -5.2 1.6e-07 0.00 0.84 0.15 FALSE
6 GTEx Skin Sun Exposed Lower leg ARAP1 0.21 0.13 lasso 7 0.13 1.2e-10 4.6 5.6 2.8e-08 0.70 0.30 0.70 FALSE
7 GTEx Skin Sun Exposed Lower leg ARAP1-AS1 0.18 0.07 lasso 7 0.06 1.0e-05 4.6 5.2 2.4e-07 0.65 0.11 0.88 FALSE
8 ROSMAP Brain Pre-frontal Cortex ARAP1 0.05 0.04 lasso 3 0.03 2.2e-04 5.6 -5.6 1.8e-08 -0.61 0.10 0.87 FALSE
9 YFS Blood NUMA1 0.02 0.02 lasso 4 0.02 2.6e-06 5.7 5.2 1.9e-07 0.01 0.01 0.99 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FAM86C 0.05 0.07 lasso 1 0.06 5.6e-05 -5.7 5.7 1.3e-08 0.00 0.00 0.99 TRUE