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chr11:70,807,773-73,149,098

Best TWAS P=2.9e-09 · Best GWAS P=1.22e-15 conditioned to 6.98e-08

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Esophagus Mucosa	ARAP1	0.27	0.25	lasso	5	0.26	2.6e-17	4.6	5.9	2.9e-09	0.74	0.78	0.22	TRUE
10	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FAM86C	0.05	0.07	lasso	1	0.06	5.6e-05	-5.7	5.7	1.3e-08	0.00	0.00	0.99	TRUE
3	GTEx	Esophagus Mucosa	ARAP1-AS2	0.12	0.08	lasso	6	0.08	3.1e-06	4.6	5.7	1.3e-08	0.72	0.02	0.95	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	ARAP1	0.05	0.04	lasso	3	0.03	2.2e-04	5.6	-5.6	1.8e-08	-0.61	0.10	0.87	FALSE
6	GTEx	Skin Sun Exposed Lower leg	ARAP1	0.21	0.13	lasso	7	0.13	1.2e-10	4.6	5.6	2.8e-08	0.70	0.30	0.70	FALSE
4	GTEx	Skin Not Sun Exposed Suprapubic	ARAP1	0.24	0.20	lasso	4	0.16	3.6e-09	4.6	5.5	4.9e-08	0.69	0.39	0.61	FALSE
5	GTEx	Skin Sun Exposed Lower leg	FAM86C1	0.40	0.31	lasso	6	0.35	7.2e-30	-4.5	-5.2	1.6e-07	0.00	0.84	0.15	FALSE
9	YFS	Blood	NUMA1	0.02	0.02	lasso	4	0.02	2.6e-06	5.7	5.2	1.9e-07	0.01	0.01	0.99	FALSE
7	GTEx	Skin Sun Exposed Lower leg	ARAP1-AS1	0.18	0.07	lasso	7	0.06	1.0e-05	4.6	5.2	2.4e-07	0.65	0.11	0.88	FALSE
1	GTEx	Brain Cerebellar Hemisphere	FAM86C1	0.35	0.20	lasso	5	0.16	5.7e-05	-4.5	-5.2	2.7e-07	0.00	0.03	0.88	FALSE