TWAS
hub
About
Usage
Models
Genes
Traits
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Traits
:
Blood Platelet Count
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chr2:30,761,670-32,184,568
Best TWAS P=3.26e-117 · Best GWAS P=1.56e-279 conditioned to 8.35e-71
30.8M
31M
31.2M
31.4M
31.6M
31.8M
32M
32.2M
0
50
100
150
200
250
300
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Esophagus Mucosa
EHD3
0.31
0.10
lasso
10
0.20
2.7e-13
-13.8
23.0
3.3e-117
-0.58
0.06
0.94
TRUE
1
CommonMind
Brain Pre-frontal Cortex
EHD3
0.16
0.09
bslmm
560
0.11
3.7e-13
11.9
15.3
7.6e-53
-0.36
0.99
0.01
TRUE
3
GTEx
Nerve Tibial
EHD3
0.16
0.07
enet
28
0.11
4.3e-08
-12.3
12.2
5.5e-34
-0.34
0.55
0.30
TRUE
4
YFS
Blood
EHD3
0.03
0.00
bslmm
541
0.00
8.4e-03
3.2
-9.1
9.7e-20
0.16
0.06
0.03
FALSE