Best TWAS P=3.26e-117 · Best GWAS P=1.56e-279 conditioned to 8.35e-71
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | EHD3 | 0.16 | 0.09 | bslmm | 560 | 0.11 | 3.7e-13 | 11.9 | 15.3 | 7.6e-53 | -0.36 | 0.99 | 0.01 | TRUE |
| 2 | GTEx | Esophagus Mucosa | EHD3 | 0.31 | 0.10 | lasso | 10 | 0.20 | 2.7e-13 | -13.8 | 23.0 | 3.3e-117 | -0.58 | 0.06 | 0.94 | TRUE |
| 3 | GTEx | Nerve Tibial | EHD3 | 0.16 | 0.07 | enet | 28 | 0.11 | 4.3e-08 | -12.3 | 12.2 | 5.5e-34 | -0.34 | 0.55 | 0.30 | TRUE |
| 4 | YFS | Blood | EHD3 | 0.03 | 0.00 | bslmm | 541 | 0.00 | 8.4e-03 | 3.2 | -9.1 | 9.7e-20 | 0.16 | 0.06 | 0.03 | FALSE |