Best TWAS P=4.39e-15 · Best GWAS P=1.41e-98 conditioned to 2.8e-107
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | ABCC4 | 0.17 | 0.03 | lasso | 5 | 0.04 | 4.4e-03 | -1.73 | 5.2 | 1.9e-07 | 0.03 | 0.24 | 0.04 | TRUE |
| 2 | GTEx | Adipose Visceral Omentum | DNAJC3-AS1 | 0.20 | 0.03 | enet | 18 | 0.11 | 2.0e-06 | -0.18 | 5.5 | 4.1e-08 | -0.16 | 0.36 | 0.08 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | ABCC4 | 0.25 | 0.12 | lasso | 7 | 0.10 | 1.3e-07 | -7.85 | 7.8 | 4.4e-15 | 0.21 | 0.99 | 0.00 | TRUE |
| 4 | GTEx | Colon Transverse | UGGT2 | 0.20 | 0.20 | enet | 12 | 0.17 | 1.2e-08 | 2.40 | 5.3 | 1.2e-07 | 0.02 | 1.00 | 0.00 | TRUE |
| 5 | GTEx | Thyroid | ABCC4 | 0.29 | 0.06 | enet | 63 | 0.16 | 3.1e-12 | 7.88 | 6.5 | 5.9e-11 | -0.12 | 1.00 | 0.00 | FALSE |
| 6 | METSIM | Adipose | ABCC4 | 0.04 | 0.00 | lasso | 3 | 0.01 | 1.1e-02 | 7.81 | -7.8 | 5.6e-15 | 0.13 | 0.16 | 0.02 | TRUE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | ABCC4 | 0.08 | 0.01 | blup | 397 | 0.04 | 1.3e-04 | 4.30 | 6.3 | 2.5e-10 | 0.02 | 0.21 | 0.02 | FALSE |