Best TWAS P=5.45e-14 · Best GWAS P=4.54e-40 conditioned to 1.66e-42
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | BTBD7 | 0.04 | 0.04 | lasso | 2 | 0.03 | 1.8e-04 | -6.1 | 6.0 | 2.6e-09 | -0.06 | 0.93 | 0.00 | FALSE |
| 2 | GTEx | Colon Sigmoid | RIN3 | 0.24 | 0.17 | lasso | 6 | 0.11 | 9.3e-05 | -5.7 | 5.8 | 6.9e-09 | -0.03 | 0.42 | 0.03 | TRUE |
| 3 | NTR | Blood | BTBD7 | 0.02 | 0.03 | lasso | 2 | 0.02 | 6.1e-08 | -6.1 | 6.1 | 8.4e-10 | -0.04 | 1.00 | 0.00 | TRUE |
| 4 | YFS | Blood | TC2N | 0.44 | 0.34 | lasso | 12 | 0.38 | 2.0e-132 | 7.1 | -7.5 | 5.5e-14 | 0.00 | 0.15 | 0.85 | TRUE |