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Traits
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Blood Platelet Count
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chr14:91,550,891-94,495,324
Best TWAS P=5.45e-14 · Best GWAS P=4.54e-40 conditioned to 1.66e-42
91.5M
92M
92.5M
93M
93.5M
94M
94.5M
0
10
20
30
40
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
YFS
Blood
TC2N
0.44
0.34
lasso
12
0.38
2.0e-132
7.1
-7.5
5.5e-14
0.00
0.15
0.85
TRUE
3
NTR
Blood
BTBD7
0.02
0.03
lasso
2
0.02
6.1e-08
-6.1
6.1
8.4e-10
-0.04
1.00
0.00
TRUE
2
GTEx
Colon Sigmoid
RIN3
0.24
0.17
lasso
6
0.11
9.3e-05
-5.7
5.8
6.9e-09
-0.03
0.42
0.03
TRUE
1
CommonMind
Brain Pre-frontal Cortex
BTBD7
0.04
0.04
lasso
2
0.03
1.8e-04
-6.1
6.0
2.6e-09
-0.06
0.93
0.00
FALSE