Best TWAS P=1.97e-29 · Best GWAS P=2.8e-21 conditioned to 0.112
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | CEP128 | 0.28 | 0.03 | enet | 36 | 0.10 | 1.6e-03 | -1.0 | 5.6 | 2.0e-08 | -0.24 | 0.19 | 0.13 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | STON2 | 0.15 | 0.07 | lasso | 3 | 0.16 | 5.6e-18 | 7.6 | -11.3 | 2.0e-29 | 0.74 | 0.00 | 1.00 | TRUE |
3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | STON2 | 0.25 | 0.17 | lasso | 6 | 0.16 | 1.1e-09 | 7.6 | -7.8 | 5.1e-15 | 0.13 | 0.99 | 0.01 | FALSE |