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chr3:87,495,550-88,911,119

Best TWAS P=7.02e-10 · Best GWAS P=1.85e-09 conditioned to 0.0133

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C3orf38	0.08	0.00	enet	14	0.04	2.3e-05	5.8	6.2	7.0e-10	0.68	0.04	0.93	TRUE
8	GTEx	Skin Not Sun Exposed Suprapubic	C3orf38	0.09	0.07	lasso	6	0.04	2.8e-03	5.8	-6.0	1.9e-09	-0.97	0.04	0.92	FALSE
6	GTEx	Nerve Tibial	C3orf38	0.09	0.05	lasso	4	0.04	6.3e-04	6.0	-6.0	2.2e-09	-1.00	0.03	0.96	FALSE
2	GTEx	Artery Aorta	C3orf38	0.06	0.06	lasso	7	0.05	6.0e-04	6.0	-6.0	2.3e-09	-1.00	0.03	0.95	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	ZNF654	0.09	0.01	lasso	7	0.06	2.7e-04	5.9	5.9	3.5e-09	0.91	0.04	0.74	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF654	0.03	0.04	lasso	3	0.03	4.6e-04	5.8	5.9	3.9e-09	0.98	0.02	0.94	FALSE
5	GTEx	Esophagus Mucosa	C3orf38	0.11	0.06	lasso	7	0.07	1.5e-05	5.7	-5.9	4.0e-09	-0.97	0.04	0.96	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C3orf38	0.02	0.03	lasso	1	0.03	1.9e-04	5.9	-5.9	4.7e-09	-0.97	0.02	0.82	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	C3orf38	0.03	0.05	lasso	1	0.05	8.1e-06	5.9	-5.9	4.7e-09	-0.97	0.02	0.98	FALSE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C3orf38	0.02	0.01	blup	24	0.02	2.0e-03	5.8	-5.8	6.7e-09	-0.98	0.02	0.80	FALSE
9	GTEx	Thyroid	C3orf38	0.12	0.08	lasso	18	0.07	1.0e-05	5.9	-5.8	7.5e-09	-0.99	0.04	0.96	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	C3orf38	0.01	0.01	lasso	3	0.01	1.2e-03	5.8	-5.7	1.1e-08	-0.99	0.01	0.73	FALSE
10	GTEx	Uterus	ZNF654	0.29	-0.01	lasso	4	0.01	1.7e-01	6.0	5.6	2.5e-08	0.97	0.03	0.70	FALSE
16	The Cancer Genome Atlas	Thyroid Carcinoma	C3orf38	0.05	0.05	blup	24	0.05	1.1e-05	6.0	-5.5	3.6e-08	-0.97	0.01	0.98	FALSE
4	GTEx	Cells Transformed fibroblasts	ZNF654	0.08	0.09	enet	6	0.10	3.1e-08	5.4	5.4	5.5e-08	0.81	0.22	0.78	FALSE
3	GTEx	Artery Tibial	C3orf38	0.11	0.03	lasso	6	0.04	3.7e-04	5.8	-5.4	7.7e-08	-0.89	0.04	0.92	FALSE
14	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C3orf38	0.04	0.01	blup	24	0.03	5.7e-03	6.0	-5.2	2.1e-07	-0.95	0.01	0.68	FALSE