Best TWAS P=2.3e-10 · Best GWAS P=6.15e-12 conditioned to 0.00686
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | KRT8P33 | 0.10 | 0.04 | lasso | 6 | 0.05 | 9.1e-04 | 5.1 | -5.5 | 3.0e-08 | -0.67 | 0.04 | 0.85 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | CEP120 | 0.06 | 0.02 | blup | 70 | 0.04 | 3.6e-03 | -4.4 | -5.8 | 7.8e-09 | -0.76 | 0.03 | 0.80 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CEP120 | 0.03 | 0.02 | enet | 5 | 0.04 | 7.3e-05 | 5.1 | -6.1 | 1.0e-09 | -0.70 | 0.04 | 0.80 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CEP120 | 0.10 | 0.14 | blup | 70 | 0.14 | 2.6e-14 | 6.8 | -6.3 | 2.3e-10 | -0.94 | 0.01 | 0.99 | TRUE |