TWAS hub - KRT8P33

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.205	0.067	0.0012	0.011	NA	0.004	NA	0.007	0.0380	NA	0.150	NA	0.08700
2	GTEx	Artery Aorta	0.104	0.040	0.0021	0.042	NA	0.010	NA	0.050	0.0024	NA	0.083	NA	0.00091
3	GTEx	Cells EBV-transformed lymphocytes	0.164	0.069	0.0050	-0.009	NA	-0.002	NA	0.005	0.8300	NA	0.370	NA	0.21000

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Diastolic blood pressure, automated reading	7.5	23.1	52.7	1.9	-7.3	-3.6
Heel T-Score	6.9	55.0	108.2	0.1	-7.5	-10.4
Pulse rate, automated reading	6.7	21.6	34.9	1.4	-5.3	-5.9
Leg predicted mass (right)	6.7	35.7	77.6	-1.4	8.8	5.2
Leg fat-free mass (right)	6.5	34.9	76.6	-1.4	8.8	5.1
Impedance of leg (right)	6.3	30.5	58.8	1.9	-7.7	-5.4
Leg predicted mass (left)	6.1	32.1	72.1	-1.2	8.5	4.8
Leg fat-free mass (left)	5.8	30.8	69.4	-1.2	8.3	4.6
Impedance of leg (left)	5.7	27.8	55.7	1.5	-7.5	-5.1
Whole body fat-free mass	5.6	31.9	71.1	-1.3	8.4	4.8
Whole body water mass	5.6	31.8	71.4	-1.1	8.4	4.8
Pulse rate	5.5	9.2	16.3	0.4	-3.4	-4.0
Trunk fat-free mass	5.0	28.5	63.9	-1.2	8.0	4.5
Trunk predicted mass	5.0	28.5	64.2	-1.2	8.0	4.5
Basal metabolic rate	5.0	27.4	62.9	-1.0	7.9	4.3
Arm predicted mass (left)	4.7	23.9	55.7	-0.5	7.5	4.0
Arm predicted mass (right)	4.6	23.4	52.4	-0.4	7.2	4.2
Systolic Blood Pressure	4.5	22.5	34.2	-1.3	-5.6	-5.8
Arm fat-free mass (left)	4.5	22.6	53.0	-0.4	7.3	3.9
Arm fat-free mass (right)	4.2	21.6	49.0	-0.1	7.0	4.0
Heel bone mineral density (BMD) T-score, automated (left)	4.0	9.0	12.0	-1.7	-3.5	-3.5
Ever unenthusiastic/disinterested for a whole week	3.9	4.8	10.0	1.8	1.0	-3.2
Impedance of whole body	3.7	18.9	31.0	1.6	-5.6	-4.8
Emphysema/chronic bronchitis	3.4	3.8	6.9	-0.6	-2.6	-2.0
High blood pressure (mother)	3.3	4.6	10.5	-0.9	-3.2	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	3.2	7.3	12.7	-1.4	-3.6	-2.7
Alzheimer’s Disease (in father)	3.1	3.4	5.8	0.9	1.9	2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.1	6.5	10.2	-1.8	2.5	3.2
Birth weight	3.0	6.5	13.0	2.0	3.6	1.5
Weight	2.8	13.6	34.1	-0.5	5.8	2.5
Qualifications: O levels/GCSEs or equivalent	2.8	4.5	11.2	-0.1	-1.5	-3.4
Family relationship satisfaction	2.8	3.4	5.9	2.0	2.4	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	2.7	8.5	18.1	-0.2	4.2	2.7
Sitting height	2.6	18.5	54.9	-0.3	7.4	0.7
Friendships satisfaction	2.6	3.2	4.0	2.0	2.0	-1.3
Commuting to job workplace: Walk	2.6	2.8	4.7	1.3	2.2	1.4
Tinnitus: Yes, now most or all of the time	2.6	3.0	6.6	-1.2	-2.6	-1.0
Had other major operations	2.5	3.0	4.4	1.4	1.7	-2.1
Forced expiratory volume in 1-second (FEV1)	2.5	8.4	16.6	-0.6	4.1	2.9
Height	2.4	45.8	119.5	-0.7	10.9	4.2
Medication: Amlodipine	2.4	3.3	5.9	-0.6	-1.9	-2.4
Neck or shoulder pain in last month	2.4	3.4	5.1	2.2	-2.2	0.6
Age started oral contraceptive pill	2.4	3.1	4.1	-2.0	1.3	1.8
Age at First Birth	2.3	3.3	5.5	-1.6	1.4	2.3
Forced expiratory volume in 1-second (FEV1), predicted	2.3	4.8	11.8	0.9	3.4	1.4
Heart disease (siblings)	2.3	2.9	7.7	0.7	-0.6	-2.8
Systolic blood pressure, automated reading	2.2	6.3	8.9	-2.1	-2.4	-3.0
Number of live births	2.2	3.1	5.9	1.8	2.4	-0.2
Pulse wave peak to peak time	2.2	2.6	4.5	0.3	2.1	1.8
Lung FEV1/FVC ratio	2.1	10.8	19.4	1.2	4.4	3.4
Pulse wave reflection index	2.1	2.6	6.8	-1.0	0.1	2.6
Medication for pain relief, constipation, heartburn	2.1	3.7	6.9	-0.2	2.6	2.0
Average weekly fortified wine intake	2.0	2.4	3.9	-1.8	2.0	0.3
Medication: Levothyroxine sodium	2.0	3.4	9.2	0.9	3.0	-0.5
Breastfed as a baby	2.0	2.5	6.5	0.8	2.6	-0.4
Number of operations (self-reported)	2.0	3.0	5.2	1.1	2.3	-1.6
Pain experienced in last month	2.0	3.3	6.5	-1.6	2.6	-0.8
Impedance of arm (right)	1.9	8.7	14.4	-0.1	-3.4	-3.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.9	2.9	5.5	2.4	0.9	-1.5
Illnesses of father: None of the above (group 1)	1.9	2.4	6.7	-2.6	-0.3	0.5
Risk taking	1.9	2.8	3.6	1.6	1.9	1.6
Pack years of smoking	1.9	2.8	7.3	2.7	0.6	0.9
Bipolar Disorder (2011)	1.8	1.7	2.7	1.1	1.1	1.6
Smoking Status	1.8	4.3	8.1	2.2	-0.5	-2.8
Medication: Ramipril	1.8	2.3	6.9	2.6	0.2	-0.2
Standing height	1.8	18.3	47.8	-0.2	6.9	2.7
Forced vital capacity (FVC), Best measure	1.8	6.8	16.4	-0.3	4.1	1.9
Mood swings	1.8	3.3	8.8	3.0	-0.6	-0.9
Body Mass Index (BMI) (2010)	1.7	2.4	4.9	-0.5	2.2	1.4
Current tobacco smoking	1.7	2.8	6.6	2.6	0.2	-1.3
Serious illness, injury or assault to yourself	1.7	2.0	5.3	0.3	2.3	-0.8
Pulse wave Arterial Stiffness index	1.7	2.0	3.1	-0.3	-1.7	-1.8
Impedance of arm (left)	1.7	8.1	12.9	0.7	-3.3	-3.6
Medication: Paracetamol	1.7	2.8	5.9	-0.2	-2.4	-1.6
Leg pain on walking	1.7	2.1	4.5	1.4	2.1	0.2
Smoking status: Current	1.7	2.8	6.6	2.6	0.4	-1.2
Ever smoked	1.7	2.9	5.1	1.9	0.2	-2.3
Respiratory disease	1.6	3.5	8.1	-0.1	-2.9	-1.5
Past tobacco smoking	1.6	3.0	7.4	-1.3	-0.0	2.7
Forced vital capacity (FVC)	1.6	6.3	14.6	-1.1	3.8	1.8
Mouth/teeth dental problems: Bleeding gums	1.6	2.1	3.3	1.7	1.8	0.3
Migraine (self-reported)	1.6	2.0	2.8	1.4	-1.7	1.1
Medication: Blood pressure	1.6	3.1	8.0	0.1	-1.1	-2.8
Heart attack/myocardial infarction (self-reported)	1.6	2.0	5.8	2.4	0.4	-0.3
Breast Cancer	1.5	3.5	4.1	-1.9	-1.7	-2.0
Blood White Count	1.5	11.3	17.5	1.4	-3.8	-4.2
Hypothyroidism (self reported)	1.5	3.4	9.9	-0.4	3.1	0.1
Medication: Co-codamol	1.5	1.8	2.1	1.4	-1.2	-1.4
Fed-up feelings	1.5	2.7	7.7	2.8	-0.3	-0.5
Waist circumference	1.5	5.6	14.3	-0.0	3.8	1.6
Happiness	1.5	1.8	2.3	1.5	1.5	0.9
Chronic bronchitis/emphysema (mother)	1.5	1.8	3.6	1.2	-0.6	-1.9
Depressed Affect (Nagel 2018)	1.4	2.8	6.5	2.5	-0.2	-1.4
Pack years adult smoking proportion	1.4	2.1	6.0	2.4	0.6	0.4
Townsend deprivation index at recruitment	1.4	2.0	3.9	-0.5	1.4	-2.0
Number of incorrect matches in round	1.4	2.4	5.1	-2.3	-1.0	1.0
Worrier / anxious feelings	1.4	2.6	6.9	-0.3	-2.6	-0.9
Blood clot in the leg (DVT)	1.4	1.8	2.7	1.6	1.6	0.0
Headache pain in last month	1.4	2.4	4.9	1.0	-2.2	1.2
High blood pressure (siblings)	1.4	2.0	4.0	1.0	-1.1	-2.0
Arm fat mass (left)	1.4	5.6	14.8	-0.2	3.9	1.3
Medication: Bendroflumethiazide	1.4	2.2	4.4	0.8	-1.3	-2.1
Worry (Nagel 2018)	1.3	2.7	4.3	1.3	-1.4	-2.1
HDL Cholesterol	1.3	2.2	3.7	-1.4	-1.9	-0.9
Cardiovascular Disease	1.3	4.3	6.5	2.5	-2.1	-1.5
Alcohol usually taken with meals	1.3	2.1	4.3	-0.9	-2.1	1.1
Heart attack	1.3	1.7	4.7	2.2	0.6	-0.3
Number of full brothers	1.3	1.7	3.7	0.1	-1.1	-1.9
Number of children fathered	1.3	1.5	2.3	0.6	-1.4	-1.5
Eye problems/disorders: Cataract	1.3	1.5	3.4	1.8	-0.5	-0.9
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	4.4	-1.2	-2.1	-0.6
Ever taken oral contraceptive pill	1.3	1.5	2.1	-1.3	1.4	0.7
Irritability	1.3	2.2	2.8	1.4	-1.7	-1.4
Reaction Time	1.2	2.4	4.6	-1.6	-0.3	-2.1
Primary Biliary Cirrhosis	1.2	1.7	3.5	1.9	1.2	0.5
Ever had hysterectomy (womb removed)	1.2	1.3	2.2	1.5	-0.3	-1.3
Hayfever, allergic rhinitis or eczema	1.2	2.6	7.7	-2.8	-0.3	-0.2
Pain all over the body in last month	1.2	1.2	3.0	-1.7	-0.8	-0.1
Hip circumference	1.2	5.4	12.0	-0.6	3.5	1.9
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	3.9	1.2	-0.8	-2.0
Hair/balding pattern: Pattern 3	1.2	1.8	2.2	-1.1	-1.5	1.5
Arm fat mass (right)	1.2	5.1	14.0	-0.4	3.7	1.1
Ever highly irritable/argumentative for 2 days	1.2	1.4	2.9	1.7	0.8	-0.9
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	6.4	-0.7	2.5	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	2.5	1.1	0.7	1.6
Back pain experienced in last month	1.2	1.8	4.9	-0.2	-2.2	-0.6
Fractured/broken bones in last 5 years	1.2	1.5	3.9	0.7	2.0	0.3
Ever depressed for a whole week	1.2	1.5	3.2	0.7	0.8	-1.8
Cholesterol lowering medication	1.2	1.8	3.0	1.3	1.7	-0.9
Alzheimer’s Disease (including proxy)	1.1	1.5	3.3	1.8	0.4	1.1
Major Depression (MDD)	1.1	1.4	3.5	1.9	-0.7	-0.3
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	4.1	2.0	0.5	-1.0
Neuroticism score	1.1	2.4	4.5	1.5	-0.7	-2.1
Alcohol intake versus 10 years previously	1.1	1.6	2.0	1.4	-0.9	-1.4
Qualifications: A levels/AS levels or equivalent	1.1	2.4	4.4	-0.1	-1.7	-2.1
Medication: Lansoprazole	1.1	1.3	2.8	-1.7	-0.5	0.9
Exposure to tobacco smoke outside home	1.1	1.4	2.6	1.0	-0.7	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	2.8	1.7	1.1	-0.6
Qualifications: College or University degree	1.1	3.4	10.0	-0.2	3.2	0.3
Medication: Blood pressure	1.1	1.9	4.2	-0.3	-2.0	-1.2
Hypertension (Self-reported)	1.1	3.2	4.7	0.6	-2.2	-2.1
Smoking status: Previous	1.1	1.6	4.5	0.4	-0.4	-2.1
Medication: Aspirin	1.1	1.5	3.5	1.9	0.4	-0.9
Miserableness	1.1	1.8	2.4	1.6	0.9	-1.5
Medication: Paracetamol	1.1	1.6	3.3	0.9	-1.8	-0.9
Average weekly beer plus cider intake	1.1	1.5	4.3	2.1	-0.5	-0.2
Vascular/heart problems diagnosed by doctor	1.1	3.1	4.6	-0.8	2.0	2.1
Neuroticism (Nagel 2018)	1.0	2.3	3.1	1.8	-1.0	-1.7
Mean Putamen Volume	1.0	1.2	2.1	-0.9	0.8	1.4
LDL Cholesterol	1.0	1.6	4.2	-0.5	-0.5	2.1
Lung FVC	1.0	5.1	7.5	-1.7	2.7	2.2
Neuroticism	1.0	2.3	3.6	1.8	-0.4	-1.9
Number of treatments/medications taken	1.0	1.8	2.8	-0.7	-1.7	-1.4
Hand grip strength (right)	1.0	2.8	4.9	-0.5	1.8	2.2
High blood pressure	1.0	2.8	4.3	0.8	-1.9	-2.1
Hearing difficulty/problems with background noise	1.0	1.7	3.7	0.3	-1.9	1.1
Illnesses of siblings	1.0	1.4	3.5	-0.6	0.6	1.9
Gout (self-reported)	1.0	1.4	2.9	-0.4	-1.1	-1.7
Comparative body size at age 10	1.0	2.7	6.7	0.5	2.6	1.1
Number of full sisters	1.0	1.2	2.0	1.0	0.7	1.4
Osteoarthritis (self-reported)	1.0	1.4	2.0	1.0	-1.4	-1.0
Hearing aid user	1.0	1.1	2.9	0.0	1.7	0.6
Mother’s age at death	1.0	1.2	2.2	-1.5	0.9	0.8
Myopia	1.0	1.5	3.0	-0.2	1.7	1.2
Bipolar Disorder (2018)	0.9	1.4	3.7	0.5	1.9	0.5
Bipolar Disorder or Schizophrenia	0.9	2.1	4.7	1.2	2.2	-0.1
Blood Platelet Count	0.9	10.6	30.7	-0.2	-5.5	-1.1
BMI	0.9	5.0	11.6	-1.0	3.4	1.6
Hearing difficulty/problems: Yes	0.9	1.4	2.1	-0.5	-1.3	1.4
Supplements: Zinc	0.9	1.0	1.2	-1.1	-0.9	-0.9
Diabetes (father)	0.9	1.1	2.0	0.6	-1.0	-1.4
Stomach or abdominal pain in last month	0.9	1.1	3.1	1.8	0.2	-0.5
Medication: Atenolol	0.9	1.2	2.6	-0.9	-1.6	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	3.1	0.1	-1.8	0.4
Illnesses of mother	0.9	1.2	2.9	0.7	1.7	0.2
Birth weight of first child	0.9	1.6	2.5	1.1	-1.0	-1.6
Wheeze or whistling in the chest in last year	0.9	1.6	2.6	-0.3	-1.6	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	1.6	1.1	0.5	1.3
Eye problems/disorders: None of the above	0.9	1.0	1.6	-0.8	0.8	1.3
Medication: Omeprazole	0.9	1.1	3.0	0.3	-1.7	-0.6
Alcohol intake frequency.	0.9	2.1	3.1	1.3	1.2	-1.8
Comparative height size at age 10	0.9	4.8	13.4	-0.4	3.7	0.9
Suffer from ‘nerves’	0.9	1.4	3.1	1.0	0.4	-1.8
Overall health rating	0.9	1.9	3.2	1.3	-0.9	-1.8
Asthma (self-reported)	0.9	1.7	4.3	-0.0	-2.1	-1.0
Ever had prostate specific antigen (PSA) test	0.9	1.1	2.6	-1.6	-0.4	0.7
Basal cell carcinoma (self-reported)	0.9	1.1	1.6	-1.3	-0.4	-1.2
Alcohol drinker status: Previous	0.9	1.0	1.5	1.2	1.2	-0.4
Neuroticism (2016)	0.8	1.2	2.0	0.8	-0.9	-1.4
Rheumatoid Arthritis	0.8	1.1	3.0	0.2	1.7	0.6
Ulcerative Colitis	0.8	1.1	2.1	1.1	1.4	0.2
Relative age of first facial hair	0.8	1.6	2.6	1.4	1.6	0.5
Diabetes (mother)	0.8	1.0	2.6	-1.6	-0.3	-0.7
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	1.8	-0.2	-0.9	1.4
Chronic bronchitis/emphysema (father)	0.8	0.9	2.5	0.4	-1.6	0.1
Body mass index (BMI)	0.8	3.4	7.8	-0.5	2.8	1.5
Trunk fat mass	0.8	3.4	9.7	-0.0	3.1	0.8
Mouth/teeth dental problems	0.8	1.2	2.0	-1.2	-1.4	0.2
Depression (self-reported)	0.8	0.9	2.0	-0.2	1.4	-0.8
Health satisfaction	0.8	1.1	1.6	1.2	1.3	-0.5
Age at last live birth	0.8	1.2	2.2	-0.4	1.5	1.1
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	1.6	-1.1	-1.3	0.3
Medication: Aspirin	0.8	1.1	2.0	1.4	0.1	-1.2
Supplements: Vitamin C	0.8	0.9	1.5	-1.1	1.2	0.3
Medication for cholesterol	0.8	1.2	3.0	0.1	0.7	1.7
Financial situation satisfaction	0.8	0.9	1.4	1.2	1.1	-0.3
Pain type(s) experienced in last month: Hip pain	0.8	1.0	2.7	1.6	0.4	0.4
Medication: Lisinopril	0.8	1.0	2.6	-0.2	0.6	-1.6
Medication: Omeprazole (e.g. Zanprol)	0.8	0.9	2.2	0.3	-1.5	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	1.9	1.4	1.1	-0.1
Prostate Cancer	0.7	1.0	3.1	0.1	1.8	0.2
HbA1C	0.7	0.7	2.2	1.5	-0.1	0.2
Type 2 Diabetes (T2D) (2012)	0.7	0.8	1.6	-1.3	0.3	0.9
Blood Red Count	0.7	6.9	19.6	-0.7	-0.9	-4.4
Allergy or Eczema	0.7	1.9	4.6	-2.1	0.7	0.7
Chronotype (morning person)	0.7	1.6	3.8	1.0	-0.1	1.9
Frequency of depressed mood in last 2 weeks	0.7	1.0	1.4	1.0	0.8	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	1.4	1.2	-0.2	-1.2
Taking other prescription medications	0.7	1.1	2.2	-1.5	0.0	-1.0
Had menopause	0.7	0.8	1.4	1.0	1.2	0.4
Allergy	0.7	1.6	3.3	1.8	1.2	0.0
Medication: Simvastatin	0.7	1.0	2.0	1.4	0.8	-0.4
Asthma	0.7	1.4	3.2	-0.0	-1.8	-0.9
Length of working week for main job	0.7	0.7	1.0	-1.0	-0.7	0.9
Medication: Ibuprofen	0.7	0.8	1.7	0.6	-1.3	0.6
Mean time to correctly identify matches	0.7	1.4	2.8	-1.1	0.1	-1.7
Whole body fat mass	0.7	3.1	8.5	-0.2	2.9	0.9
Chest pain or discomfort	0.7	1.0	2.0	0.4	-1.0	-1.4
Had major operations	0.7	0.8	2.3	1.5	0.2	0.3
Ever had bowel cancer screening	0.7	0.8	1.8	-1.3	-0.8	0.3
Breast cancer (self-reported)	0.7	0.8	1.3	1.1	1.1	-0.2
Osteoporosis (self-reported)	0.7	0.9	1.6	-0.5	1.0	1.2
Number of self-reported non-cancer illnesses	0.7	1.2	3.0	-0.2	-0.8	-1.7
Commuting to job workplace: Cycle	0.7	0.8	2.0	-0.6	0.0	1.4
Depression (Nagel 2018)	0.6	0.8	1.6	1.3	-0.4	-0.9
Alzheimer’s Disease (in mother)	0.6	0.7	1.1	1.1	-0.9	-0.2
Ulcerative Colitis (UC)	0.6	1.1	2.8	1.7	0.7	-0.2
Ovarian Cancer	0.6	0.8	1.1	-1.0	-0.4	-1.0
Hand grip strength (left)	0.6	1.6	3.8	-0.9	0.3	2.0
Sensitivity / hurt feelings	0.6	1.1	3.1	-0.1	1.8	0.4
Nervous feelings	0.6	1.2	2.9	0.1	-1.7	-0.8
Financial difficulties in last 2 years	0.6	0.8	1.4	1.2	1.0	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.5	-0.6	1.2	0.4
Lung cancer (father)	0.6	0.8	1.7	-0.2	0.7	1.3
Exposure to tobacco smoke at home	0.6	0.6	1.2	-0.8	1.1	-0.1
Tense / ‘highly strung’	0.6	1.1	1.7	1.3	-0.8	-0.9
Hair/balding pattern: Pattern 4	0.6	1.4	3.9	0.2	-2.0	-0.6
Worry too long after embarrassment	0.6	1.1	1.5	0.6	-1.2	-1.2
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	2.2	-0.4	-1.5	0.1
Illnesses of siblings: Diabetes	0.6	0.7	1.1	-1.0	-1.1	-0.3
Average weekly red wine intake	0.6	0.9	1.7	0.5	1.3	0.9
Long-standing illness, disability or infirmity	0.6	0.9	2.2	-0.2	0.7	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.9	-0.1	-1.4	0.3
High cholesterol (Self-reported)	0.6	1.1	3.2	1.8	0.1	0.3
Schizophrenia (2018)	0.5	1.1	1.5	1.2	1.2	-0.5
Coronary Artery Disease (CAD)	0.5	0.6	0.6	-0.8	-0.8	-0.7
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.1	-0.3	-0.8	-1.1
Severe depression (siblings)	0.5	0.6	1.0	0.7	0.4	1.0
Qualifications: None of the above	0.5	1.0	2.5	1.6	0.4	0.6
Falls in the last year	0.5	0.7	1.6	0.5	1.3	0.6
Prospective memory result	0.5	0.6	1.1	0.1	-1.1	0.8
Shortness of breath walking on level ground	0.5	0.5	0.9	0.6	-1.0	-0.6
Commuting to job workplace: Car/motor vehicle	0.5	0.6	0.9	-0.4	-0.9	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.1	-0.7	-1.1	-0.4
Guilty feelings	0.5	0.8	2.2	0.4	0.2	-1.5
Wears glasses or contact lenses	0.5	0.5	1.1	0.5	-1.1	0.5
Leg fat mass (left)	0.5	1.9	4.6	-0.3	2.1	1.0
Intelligence (Savage-Jansen 2018)	0.4	1.3	2.3	0.7	1.0	-1.5
Schizophrenia (2014)	0.4	0.9	2.1	0.6	1.4	0.4
Ever used hormone-replacement therapy (HRT)	0.4	0.5	0.7	0.7	-0.8	-0.5
Medication: Metformin	0.4	0.6	1.0	-1.0	0.8	-0.3
Qualifications: CSEs or equivalent	0.4	0.5	1.0	0.1	0.7	-1.0
Supplements: Glucosamine	0.4	0.5	1.6	0.0	-0.2	1.2
Hair/balding pattern: Pattern 2	0.4	0.5	1.0	0.5	1.0	0.6
Time employed in main current job	0.4	0.5	1.5	0.1	-0.0	1.2
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.6	0.8	-0.5	-0.8
Medication: Allopurinol	0.4	0.6	1.0	-0.1	-0.8	-1.0
Leg fat mass (right)	0.4	1.7	4.2	-0.2	2.0	0.9
Illnesses of father: Heart disease	0.4	0.6	1.4	1.2	0.3	0.4
Illnesses of father: High blood pressure	0.4	0.5	1.0	1.0	-0.1	-0.7
Schizophrenia vs Biploar Disorder	0.3	0.3	0.7	-0.6	-0.8	0.1
Crohns Disease (2017)	0.3	0.6	1.6	-1.3	-0.4	0.1
Fasting Glucose	0.3	0.3	0.9	-1.0	-0.1	0.3
Vitamin and mineral supplements	0.3	0.4	1.0	1.0	0.4	-0.2
Age when periods started (menarche)	0.3	0.8	2.1	0.2	-0.4	1.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.0	-0.0	-0.3	1.0
Multivitamins +/- minerals	0.3	0.4	1.0	-0.6	-0.2	1.0
Diabetes (self-reported)	0.3	0.5	0.9	-1.0	0.8	0.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.2	-1.1	-0.2	-0.0
Mouth/teeth dental problems: Dentures	0.3	0.5	1.2	-0.1	1.1	0.7
Loud music exposure frequency	0.3	0.3	0.6	-0.8	-0.2	0.6
Leg fat percentage (right)	0.3	1.2	2.0	0.4	-1.4	-1.3
Age at first live birth	0.3	0.5	0.7	-0.6	0.7	0.9
Heart disease (mother)	0.3	0.4	1.1	-0.3	1.0	-0.3
Knee pain experienced in last month	0.3	0.5	0.8	0.9	0.2	0.8
Diabetes diagnosed by doctor	0.3	0.5	1.1	-1.0	0.7	-0.0
Qualifications: nursing, teaching	0.3	0.4	0.8	-0.9	0.4	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.5	-0.7	0.1	-0.6
Medication: Gliclazide	0.3	0.4	0.9	-0.4	0.4	-0.9
Average weekly champagne plus white wine intake	0.3	0.4	0.7	-0.8	0.1	0.7
Crohns Disease (2012)	0.2	0.3	0.6	0.4	-0.3	0.7
Lupus	0.2	0.2	0.3	-0.5	0.5	0.4
Type 2 Diabetes (T2D) (2018)	0.2	0.5	1.1	-1.0	-0.6	-0.1
Hair Pigment	0.2	4.3	7.5	-2.0	-2.7	-1.3
Average weekly spirits intake	0.2	0.2	0.5	-0.3	-0.2	0.7
Maternal smoking around birth	0.2	0.3	0.5	0.7	-0.6	-0.3
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	0.3	-0.7	-0.1
Fluid intelligence score	0.2	0.3	0.6	0.8	0.0	-0.6
Arm fat percentage (right)	0.2	0.8	2.3	-0.5	1.5	-0.1
Father’s age at death	0.2	0.3	0.6	0.0	0.5	-0.8
Noisy workplace	0.2	0.3	0.5	-0.5	-0.7	0.2
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.8	-0.6	0.9	-0.0
Arm fat percentage (left)	0.2	0.8	2.2	-0.2	1.5	0.1
Commuting to job workplace: Public transport	0.2	0.2	0.5	0.1	0.3	0.7
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.4	-0.2	-0.6	-0.6
Medication: Atorvastatin	0.2	0.3	0.4	0.5	0.3	0.7
Alcohol drinker status: Never	0.2	0.3	0.4	0.2	0.6	-0.6
Leg fat percentage (left)	0.2	0.9	1.6	0.2	-1.3	-1.0
Supplements: Calcium	0.2	0.2	0.4	-0.6	0.5	-0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.5	0.7	0.3	-0.2
Triglycerides	0.1	0.2	0.3	0.1	-0.5	0.4
Blood Eosinophil Count	0.1	0.7	1.3	0.6	-1.1	-0.7
Waist Hip Ratio (WHR)	0.1	0.7	1.4	0.7	0.2	-1.2
Tanning	0.1	1.1	1.6	0.9	-1.3	0.9
Angina	0.1	0.1	0.2	-0.3	0.2	-0.4
Medication for hormone replacement therapy	0.1	0.1	0.3	-0.3	-0.1	0.5
Trunk fat percentage	0.1	0.6	1.4	0.4	1.2	-0.4
Peak expiratory flow (PEF)	0.1	0.3	0.5	0.6	-0.3	0.7
Glaucoma (self-reported)	0.1	0.1	0.3	-0.1	0.0	0.5
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.4	0.6	0.1	-0.0
Angina (self-reported)	0.1	0.1	0.3	-0.3	0.2	-0.6
Medication: Seretide 50 evohaler	0.1	0.1	0.1	-0.1	0.4	-0.4
Loneliness, isolation	0.1	0.2	0.4	0.2	0.6	-0.3
Mineral and other dietary supplements	0.1	0.1	0.1	0.2	0.4	-0.3
Eye problems/disorders: Glaucoma	0.1	0.1	0.1	-0.3	-0.2	0.3
Unable to work because of sickness or disability	0.1	0.1	0.2	0.3	-0.1	-0.5
Irritable Bowel Disease (IBD)	0.0	0.1	0.1	0.3	0.3	-0.1
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.0	-0.2	0.1	0.1
Relative age voice broke	0.0	0.0	0.1	0.2	0.3	0.0
Medication: Cholesterol lowering	0.0	0.0	0.0	0.1	-0.0	-0.0
Body fat percentage	0.0	0.2	0.3	0.3	0.5	-0.4
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.1	-0.0	0.1	-0.2

Hub : Genes

KRT8P33

Models

Trait associations