Best TWAS P=8.11e-11 · Best GWAS P=2.58e-20 conditioned to 4.03e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | MXD3 | 0.47 | 0.20 | lasso | 10 | 0.22 | 7.7e-07 | -3.7 | -6.5 | 8.1e-11 | -0.49 | 0.02 | 0.82 | TRUE |
| 2 | GTEx | Lung | MXD3 | 0.20 | 0.12 | lasso | 10 | 0.12 | 1.8e-09 | -3.7 | -5.4 | 5.6e-08 | -0.33 | 0.95 | 0.04 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | RGS14 | 0.19 | 0.05 | enet | 16 | 0.05 | 6.6e-04 | -2.6 | 5.1 | 2.7e-07 | 0.42 | 0.12 | 0.34 | TRUE |