TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Blood Platelet Count
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chr5:157,991,815-160,235,125
Best TWAS P=2.28e-22 · Best GWAS P=6.78e-86 conditioned to 1.36e-62
158M
158.5M
159M
159.5M
160M
0
20
40
60
80
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Lung Adenocarcinoma
UBLCP1
0.04
0.03
lasso
2
0.03
2.1e-04
-9.4
-9.7
2.3e-22
0.02
0.17
0.37
TRUE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
PWWP2A
0.04
0.05
lasso
3
0.04
4.7e-05
-1.6
-7.2
5.7e-13
-0.14
0.48
0.24
TRUE
1
GTEx
Skin Not Sun Exposed Suprapubic
PWWP2A
0.18
0.13
lasso
2
0.11
1.4e-06
3.6
5.3
9.9e-08
0.11
0.88
0.00
TRUE
2
YFS
Blood
UBLCP1
0.07
0.03
bslmm
411
0.05
6.0e-17
4.0
-6.3
3.2e-10
0.04
0.86
0.13
FALSE