Best TWAS P=2.28e-22 · Best GWAS P=6.78e-86 conditioned to 1.36e-62
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | PWWP2A | 0.18 | 0.13 | lasso | 2 | 0.11 | 1.4e-06 | 3.6 | 5.3 | 9.9e-08 | 0.11 | 0.88 | 0.00 | TRUE |
| 2 | YFS | Blood | UBLCP1 | 0.07 | 0.03 | bslmm | 411 | 0.05 | 6.0e-17 | 4.0 | -6.3 | 3.2e-10 | 0.04 | 0.86 | 0.13 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | UBLCP1 | 0.04 | 0.03 | lasso | 2 | 0.03 | 2.1e-04 | -9.4 | -9.7 | 2.3e-22 | 0.02 | 0.17 | 0.37 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PWWP2A | 0.04 | 0.05 | lasso | 3 | 0.04 | 4.7e-05 | -1.6 | -7.2 | 5.7e-13 | -0.14 | 0.48 | 0.24 | TRUE |