Best TWAS P=2.17e-10 · Best GWAS P=4.01e-06 conditioned to 0.802
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | KANSL1 | 0.18 | 0.00 | lasso | 2 | 0.00 | 4.3e-01 | -5.0 | 6.3 | 2.2e-10 | -0.75 | 0.00 | 0.25 | TRUE |
| 2 | GTEx | Nerve Tibial | KANSL1 | 0.31 | 0.06 | lasso | 2 | 0.13 | 3.4e-09 | -1.6 | 5.5 | 4.8e-08 | -0.21 | 0.04 | 0.07 | FALSE |
| 3 | GTEx | Testis | KANSL1 | 0.19 | 0.05 | enet | 10 | 0.09 | 6.6e-05 | -5.0 | 5.3 | 8.6e-08 | -0.53 | 0.01 | 0.36 | FALSE |
| 4 | GTEx | Thyroid | KANSL1 | 0.26 | 0.02 | enet | 16 | 0.10 | 7.8e-08 | 1.9 | 6.0 | 1.7e-09 | -0.63 | 0.02 | 0.76 | FALSE |